Abolfazl Akbarzadeh

Summary

Affiliation: Tabriz University of Medical Sciences
Country: Iran

Publications

  1. ncbi request reprint PLGA-based nanoparticles as cancer drug delivery systems
    Fatemeh Sadat Tabatabaei Mirakabad
    Department of Medical Hematology, Faculty of Advanced Medical Science, Tabriz University of Medical Science, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 15:517-35. 2014
  2. ncbi request reprint Physicochemical characteristics of Fe3O4 magnetic nanocomposites based on Poly(N-isopropylacrylamide) for anti-cancer drug delivery
    Soodabeh Davaran
    Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 15:49-54. 2014
  3. pmc Liposome: classification, preparation, and applications
    Abolfazl Akbarzadeh
    Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    Nanoscale Res Lett 8:102. 2013
  4. pmc Quantum dots: synthesis, bioapplications, and toxicity
    Alireza Valizadeh
    Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, 51664, Iran
    Nanoscale Res Lett 7:480. 2012
  5. pmc Synthesis, characterization and in vitro studies of doxorubicin-loaded magnetic nanoparticles grafted to smart copolymers on A549 lung cancer cell line
    Abolfazl Akbarzadeh
    Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, Iran
    J Nanobiotechnology 10:46. 2012
  6. ncbi request reprint Comparison of inhibitory effect of 17-DMAG nanoparticles and free 17-DMAG in HSP90 gene expression in lung cancer
    Hassan Mellatyar
    Department of Medical Biotechnology, Faculty of Advance Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 15:8693-8. 2014
  7. doi request reprint Synthesis, characterization, and in vitro studies of PLGA-PEG nanoparticles for oral insulin delivery
    Sara Hosseininasab
    Department of Medicinal Chemistry and Drug Applied Research Center, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, 51368, Iran
    Chem Biol Drug Des 84:307-15. 2014
  8. ncbi request reprint Inhibitory effects of β-cyclodextrin-helenalin complexes on H-TERT gene expression in the T47D breast cancer cell line - results of real time quantitative PCR
    Samaneh Ghasemali
    Drug Applied Research Center, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 14:6949-53. 2013
  9. doi request reprint Up regulation of liver-enriched transcription factors HNF4a and HNF6 and liver-specific microRNA (miR-122) by inhibition of let-7b in mesenchymal stem cells
    Effat Alizadeh
    Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
    Chem Biol Drug Des 85:268-79. 2015
  10. ncbi request reprint PAMAM dendrimers augment inhibitory effects of curcumin on cancer cell proliferation: possible inhibition of telomerase
    Mahdie Mollazade
    Tuberculosis and Lung Research Center, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 14:6925-8. 2013

Collaborators

  • Sang Woo Joo
  • Mohamadreza Baghaban Eslaminejad
  • Abolfazl Barzegar
  • Kazem Nejati-Koshki
  • Nosratollah Zarghami
  • Soodabeh Davaran
  • Effat Alizadeh
  • Masoud Gandomkar Ghalhar
  • Hassan Mellatyar
  • Hassan Dariushnejad
  • Amir Ahmad Khandaghi
  • Amin Barkhordari
  • Zahra Davoudi
  • Nosratallah Zarghami
  • Sara Hosseininasab
  • Younes Hanifehpour
  • Somayeh Alimohammadi
  • Mohammad Rahmati
  • Fariba Badrzadeh
  • Jalil Karnoosh-Yamchi
  • Fatemeh Sadat Tabatabaei Mirakabad
  • Mohammad Rahmati Yamchi
  • Mahdie Mollazade
  • Samaneh Ghasemali
  • Alireza Valizadeh
  • Shahryar Hashemzadeh
  • Hamid Tayefi Nasrabadi
  • Hamed Hamishehkar
  • Roya Salehi
  • Ali Akbar Movassaghpour
  • Ali Reza Ostad-Rahimi
  • Vahideh Zeighamian
  • Mojtaba Abbasian
  • Mehran Mesgari
  • Mozhgan Abasi
  • Akbar Darbin
  • Farhad Abbasalizadeh
  • Ali Etemadi
  • Mortaza Milani
  • Hossein Samadi Kafil
  • Vahide Zeighamian
  • Morteza Taheri
  • Samira Alimirzalu
  • Majid Mobasseri
  • Mohammad Rahmatiyamchi
  • Mohammad Rahmati-Yamchi
  • Eommolbanin Ebrahimi
  • Roghiyeh Pashaei-Asl
  • Mohammad Pourhasan-Moghaddam
  • Sedigeh Fekri Aval
  • Alireza Abhari
  • Zohre Sadeghi
  • Amirbahman Rahimzadeh
  • Zahra Bahmani
  • Fateme Sadate Tabatabae
  • Mohsen Alipour
  • Hamid Tayef Nasrabadi
  • Mohamad Rahmati-Yamchi
  • Elham Tafsiri
  • Rana Jahanban-Esfahlan
  • Marzieh Nasiri
  • Abbas Alibakhshi
  • Mozhgan Abbasi
  • Majid Tozihi
  • Shirafkan Kordi
  • Mohammad Samiei
  • Samad Mussa Farkhani
  • Nosratalah Zarghami
  • Mohammad Kouhi
  • Haleh Mikaeili

Detail Information

Publications18

  1. ncbi request reprint PLGA-based nanoparticles as cancer drug delivery systems
    Fatemeh Sadat Tabatabaei Mirakabad
    Department of Medical Hematology, Faculty of Advanced Medical Science, Tabriz University of Medical Science, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 15:517-35. 2014
    ..Increasing experience in the application of PLGA nanoparticles has provided a promising future for use of these nanoparticles in cancer treatment, with high efficacy and few side effects. ..
  2. ncbi request reprint Physicochemical characteristics of Fe3O4 magnetic nanocomposites based on Poly(N-isopropylacrylamide) for anti-cancer drug delivery
    Soodabeh Davaran
    Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 15:49-54. 2014
    ..The incorporation of nanoparticulates into a hydrogel matrix can result in unique material characteristics such as enhanced mechanical properties, swelling response, and capability of remote controlled actuation...
  3. pmc Liposome: classification, preparation, and applications
    Abolfazl Akbarzadeh
    Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz 51664, Iran
    Nanoscale Res Lett 8:102. 2013
    ....
  4. pmc Quantum dots: synthesis, bioapplications, and toxicity
    Alireza Valizadeh
    Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, 51664, Iran
    Nanoscale Res Lett 7:480. 2012
    ..Due to the small structures of QDs, some physical properties such as optical and electron transport characteristics are quite different from those of the bulk materials...
  5. pmc Synthesis, characterization and in vitro studies of doxorubicin-loaded magnetic nanoparticles grafted to smart copolymers on A549 lung cancer cell line
    Abolfazl Akbarzadeh
    Department of Medical Nanotechnology, Faculty of Advanced Medical Science, Tabriz University of Medical Sciences, Tabriz, Iran
    J Nanobiotechnology 10:46. 2012
    ..These modified SPIONs were used for encapsulation of anticancer drug doxorubicin...
  6. ncbi request reprint Comparison of inhibitory effect of 17-DMAG nanoparticles and free 17-DMAG in HSP90 gene expression in lung cancer
    Hassan Mellatyar
    Department of Medical Biotechnology, Faculty of Advance Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 15:8693-8. 2014
    ..The purpose of this study was to examine whether nanocapsulating 17DMAG improves the anti cancer effect over free 17DMAG in the A549 lung cancer cell line...
  7. doi request reprint Synthesis, characterization, and in vitro studies of PLGA-PEG nanoparticles for oral insulin delivery
    Sara Hosseininasab
    Department of Medicinal Chemistry and Drug Applied Research Center, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, 51368, Iran
    Chem Biol Drug Des 84:307-15. 2014
    ..The focus of this research is synthetization and characterization of hydrogels PLGA-PEG insulin nanoparticles and also pH sensitivity of insulin nanoparticles was investigated. ..
  8. ncbi request reprint Inhibitory effects of β-cyclodextrin-helenalin complexes on H-TERT gene expression in the T47D breast cancer cell line - results of real time quantitative PCR
    Samaneh Ghasemali
    Drug Applied Research Center, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 14:6949-53. 2013
    ..Cyclodextrin (β-CD) is a cyclic oligosaccharide comprising seven D-glucopyranoside units, linked through 1,4-glycosidic bonds...
  9. doi request reprint Up regulation of liver-enriched transcription factors HNF4a and HNF6 and liver-specific microRNA (miR-122) by inhibition of let-7b in mesenchymal stem cells
    Effat Alizadeh
    Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
    Chem Biol Drug Des 85:268-79. 2015
    ..The findings of this work might help optimization of in vitro hepatogenic differentiation utilizing microRNAs and hAT-MSCs that could be used for therapeutic purposes...
  10. ncbi request reprint PAMAM dendrimers augment inhibitory effects of curcumin on cancer cell proliferation: possible inhibition of telomerase
    Mahdie Mollazade
    Tuberculosis and Lung Research Center, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 14:6925-8. 2013
    ..In this study, we investigated the comparative antiproliferative effect of PAMAM encapsulating curcumin with naked curcumin on the T47D breast cancer cell line...
  11. ncbi request reprint Molecular target therapy of AKT and NF-kB signaling pathways and multidrug resistance by specific cell penetrating inhibitor peptides in HL-60 cells
    Zahra Davoudi
    Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 15:4353-8. 2014
    ..We therefore used cell penetrating inhibitor peptides to define the contributions of AKT and NF-kB to survival and multi drug resistance (MDR) in HL-60 cells...
  12. ncbi request reprint Comparison of inhibitory effects of 17-AAG nanoparticles and free 17-AAG on HSP90 gene expression in breast cancer
    Masoud Gandomkar Ghalhar
    Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 15:7113-8. 2014
    ..17-AAG has poor water-solubility which is a potential problem for clinical practice. In this study for improving the stability and solubility of molecules in drug delivery systems we used a β-cyclodextrin- 17AAG complex...
  13. pmc Preparation and in vitro evaluation of doxorubicin-loaded Fe₃O₄ magnetic nanoparticles modified with biocompatible copolymers
    Abolfazl Akbarzadeh
    Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Int J Nanomedicine 7:511-26. 2012
    ..The magnetic properties conferred by superparamagnetic iron oxide nanoparticles could help to maintain the nanoparticles in the joint with an external magnet...
  14. doi request reprint Preparation of pH sensitive insulin-loaded nano hydrogels and evaluation of insulin releasing in different pH conditions
    Jalil Karnoosh-Yamchi
    Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    Mol Biol Rep 41:6705-12. 2014
    ..8 is the most. Results showed that by opting suitable polymerization method and selecting the best nanohydrogels, we could obtain a suitable insulin loaded nanohydrogels for oral administration...
  15. doi request reprint Synthesis and in vitro study of cisplatin-loaded Fe3O4 nanoparticles modified with PLGA-PEG6000 copolymers in treatment of lung cancer
    Kazem Nejati-Koshki
    Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
    J Microencapsul 31:815-23. 2014
    ..This approach has the prospective to overcome some major limitations of conventional chemotherapy and may be a promising strategy for future applications in lung cancer therapy...
  16. ncbi request reprint Comparison between effects of free curcumin and curcumin loaded NIPAAm-MAA nanoparticles on telomerase and PinX1 gene expression in lung cancer cells
    Fariba Badrzadeh
    Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 15:8931-6. 2014
    ..In this article, we compared the effects of pure curcumin and curcumin-loaded NIPAAm-MAA nanoparticles on telomerase and PinX1 gene expression in a lung cancer cell line...
  17. ncbi request reprint Inhibition of leptin and leptin receptor gene expression by silibinin-curcumin combination
    Kazem Nejati-Koshki
    Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran E mail
    Asian Pac J Cancer Prev 14:6595-9. 2014
    ..In conclusion, these herbal compounds inhibit the expression and secretion of leptin and it could probably be used as drug candidates for breast cancer therapy through leptin targeting in the future. ..
  18. pmc Magnetic nanoparticles: preparation, physical properties, and applications in biomedicine
    Abolfazl Akbarzadeh
    Faculty of Pharmacy, Department of Medicinal Chemistry and Drug Applied Research Center Tabriz University of Medical Sciences, Tabriz, 51368, Iran
    Nanoscale Res Lett 7:144. 2012
    ..Then, different methodologies for the functionalization of the prepared MNPs together with the characterization techniques are explained. Theorical views on the magnetism of nanoparticles are considered...