Affiliation: Shahid Beheshti University
- Quality by design: optimization of a liquid filled pH-responsive macroparticles using Draper-Lin composite designHasan Rafati
Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G C, Evin, Tehran, Iran
J Pharm Sci 98:2401-11. 2009..The optimized macroparticles were predicted to yield 93.4% encapsulation efficiency and 72.8% PO loading, which were remarkably close to the experimental values of 89.2% and 69.5%, consequently...
- Experimental design and desirability function approach for development of novel anticancer nanocarrier delivery systemsH Rafati
Department of Chemical Engineering, Medicinal Plants and Drugs Research Institute, Shahid Beheshti Univ, G C, Evin, Tehran, Iran
Pharmazie 66:31-6. 2011..The overall results demonstrate the implication of desirability functionin experimental design as a beneficial approach in nanoparticle drug delivery design...
- Investigation of the solid state properties of amoxicillin trihydrate and the effect of powder pHAlireza Ghassempour
Medicinal Plants and Drugs Research Institute MPDRI, Shahid Beheshti University, Evin, PO Box 19835 389, Tehran, Iran
AAPS PharmSciTech 8:E93. 2007..Recrystallization studies confirmed that the powder pH could be controlled by adjusting the pH of the crystallization...
- Determination of N-vinyl-2-pyrrolidone and N-methyl-2-pyrrolidone in drugs using polypyrrole-based headspace solid-phase microextraction and gas chromatography-nitrogen-phosphorous detectionAli Mehdinia
Department of Chemistry, Faculty of Science, Tarbiat Modares University, Tehran, Iran
Anal Chim Acta 587:82-8. 2007..In addition, the method was used for simultaneous detection of NVP, 2-pyrrolidone (2-Pyr), gamma-butyrolactone (GBL) and ethanolamine (EA) compounds...
- A new solution for a chronic problem; aqueous enteric coatingHasan Rafati
Medicinal Plants and Drugs Research Institute MPDRI, Shahid Beheshti University, Evin 19835 389, Tehran, Iran
J Pharm Sci 95:2432-7. 2006..The enteric tablets maintain their shapes in acid medium and passed the USP dissolution test for DR ASA tablets...
- Preconcentration and determination of ultra-traces of platinum in human serum using the combined electrodeposition-electrothermal atomic absorption spectroscopy (ED-ETAAS) and chemometric methodNahid Mashkouri Najafi
Department of Chemistry, Faculty of Science, Shahid Beheshti Uinversity, Evin, Tehran, Iran
J Pharm Biomed Anal 53:58-61. 2010..A relatively good reproducibility %RSD=2.44, low limit of detection LOD=2.54 microg/L and promising characteristic mass m(o)=91.30 pg were obtained using this technique...