Mohammad Reza Safarinejad

Summary

Affiliation: Shaheed Beheshti University of Medical Sciences
Country: Iran

Publications

  1. doi Relationship of omega-3 and omega-6 fatty acids with semen characteristics, and anti-oxidant status of seminal plasma: a comparison between fertile and infertile men
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Department of Urology, Shahid Modarress Hospital, Shahid Beheshti University MC, Tehran, Iran
    Clin Nutr 29:100-5. 2010
  2. doi Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double-blind, placebo controlled, randomized study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University, MC, Tehran, Islamic Republic of Iran
    J Urol 181:741-51. 2009
  3. doi Efficacy of coenzyme Q10 on semen parameters, sperm function and reproductive hormones in infertile men
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University, Tehran, Iran
    J Urol 182:237-48. 2009
  4. ncbi Safety and efficacy of escitalopram in the treatment of premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized study
    Mohammad Reza Safarinejad
    Department of Urology, Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Clin Psychopharmacol 27:444-50. 2007
  5. ncbi Erectile dysfunction: clinical guidelines (1)
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Urol J 1:133-47. 2004
  6. ncbi Once-daily high-dose pindolol for paroxetine-refractory premature ejaculation: a double-blind, placebo-controlled and randomized study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Clin Psychopharmacol 28:39-44. 2008
  7. ncbi The role of endothelial nitric oxide synthase (eNOS) T-786C, G894T, and 4a/b gene polymorphisms in the risk of idiopathic male infertility
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Centre, Shahid Beheshti University MC, Tehran, Iran
    Mol Reprod Dev 77:720-7. 2010
  8. doi An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment
    M R Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University MC, Tehran, Iran
    Int J Impot Res 22:240-50. 2010
  9. doi The association of glutathione-S-transferase gene polymorphisms (GSTM1, GSTT1, GSTP1) with idiopathic male infertility
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University MC, Tehran, Iran
    J Hum Genet 55:565-70. 2010
  10. ncbi The effects of the adjunctive bupropion on male sexual dysfunction induced by a selective serotonin reuptake inhibitor: a double-blind placebo-controlled and randomized study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University, Tehran, Iran
    BJU Int 106:840-7. 2010

Collaborators

  • Ali-Asghar kolahi
  • Alireza Farshi
  • Alireza Khoshdel
  • Alireza Babaei
  • Ali Asghari
  • A Basiri
  • Farid Dadkhah
  • Erfan Amini
  • S Y Hosseini
  • Mandana Mansour Ghanaie
  • Ladan Hosseini
  • Mohammad Soleimani
  • Elham Iran-Pour
  • Seyed Yousef Hosseini
  • Seyyed Yousof Hosseini
  • F Dadkhah
  • A R Naderi
  • Aliakbar Allahkhah
  • Seyyed Alaeddin Asgari
  • Nassrin Dadrass
  • Ali Reza Lashay
  • Alireza Lashay
  • Amir Hossein Farokhpey
  • A Lashay
  • M A Asgari
  • Hassan Hooshyar
  • Majid Ali Asgari
  • E Amini
  • Ahmad Tara
  • A Nahabedian
  • M Parvin
  • T Javadzadeh
  • A K Danesh

Detail Information

Publications91

  1. doi Relationship of omega-3 and omega-6 fatty acids with semen characteristics, and anti-oxidant status of seminal plasma: a comparison between fertile and infertile men
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Department of Urology, Shahid Modarress Hospital, Shahid Beheshti University MC, Tehran, Iran
    Clin Nutr 29:100-5. 2010
    ..The aim was to evaluate polyunsaturated fatty acid (PUFA) composition of the blood plasma and spermatozoa in infertile men with idiopathic oligoasthenoteratozoospermia (OAT)...
  2. doi Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double-blind, placebo controlled, randomized study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University, MC, Tehran, Islamic Republic of Iran
    J Urol 181:741-51. 2009
    ..We explored the efficacy of selenium and/or or N-acetyl-cysteine for improving semen parameters in infertile men, and the associations among semen quality and the concentrations of selenium and N-acetyl-cysteine in seminal plasma...
  3. doi Efficacy of coenzyme Q10 on semen parameters, sperm function and reproductive hormones in infertile men
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University, Tehran, Iran
    J Urol 182:237-48. 2009
    ..We determined the efficacy of coenzyme Q10 supplementation on semen parameters, sperm function and reproductive hormone profiles in infertile men...
  4. ncbi Safety and efficacy of escitalopram in the treatment of premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized study
    Mohammad Reza Safarinejad
    Department of Urology, Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Clin Psychopharmacol 27:444-50. 2007
    ..To evaluate the efficacy and safety of most selective serotonin reuptake inhibitor drug, escitalopram, in delaying ejaculation in patients with premature ejaculation (PE)...
  5. ncbi Erectile dysfunction: clinical guidelines (1)
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Urol J 1:133-47. 2004
    ..We present a framework for the evaluation, treatment, and follow-up of the male patient who presents with erectile dysfunction...
  6. ncbi Once-daily high-dose pindolol for paroxetine-refractory premature ejaculation: a double-blind, placebo-controlled and randomized study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Clin Psychopharmacol 28:39-44. 2008
    ..To evaluate the efficacy and safety of pindolol 7.5 mg/d in delaying of ejaculation in paroxetine-refractory patients...
  7. ncbi The role of endothelial nitric oxide synthase (eNOS) T-786C, G894T, and 4a/b gene polymorphisms in the risk of idiopathic male infertility
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Centre, Shahid Beheshti University MC, Tehran, Iran
    Mol Reprod Dev 77:720-7. 2010
    ..01). We also found an association between the eNOS "-786C," "894T," and "a" alleles and an increased risk of poor semen parameters. Our data revealed a significant relationship between eNOS genotypes and the phenotype of infertility...
  8. doi An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment
    M R Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University MC, Tehran, Iran
    Int J Impot Res 22:240-50. 2010
    ..4 vs 25.4, P=0.001). Mean per patient 'yes' responses to GEQ was 91.2 and 4.2% for sildenafil and saffron, respectively (P=0.0001). These findings do not support a beneficial effect of saffron administration in men with ED...
  9. doi The association of glutathione-S-transferase gene polymorphisms (GSTM1, GSTT1, GSTP1) with idiopathic male infertility
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University MC, Tehran, Iran
    J Hum Genet 55:565-70. 2010
    ..44; 95% CI: 0.29-0.78, P=0.004). These results support the hypothesis of increased risk of GSTM1 or GSTT1null genotypes for developing infertility, but the nondeletion GSTM1 and GSTT1genotypes emerged as protective factors...
  10. ncbi The effects of the adjunctive bupropion on male sexual dysfunction induced by a selective serotonin reuptake inhibitor: a double-blind placebo-controlled and randomized study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University, Tehran, Iran
    BJU Int 106:840-7. 2010
    ....
  11. doi Midodrine for the treatment of organic anejaculation but not spinal cord injury: a prospective randomized placebo-controlled double-blind clinical study
    M R Safarinejad
    Department of Urology, Urology and Nephrology Research Center, Shahid Beheshti University MC, Tehran, Iran
    Int J Impot Res 21:213-20. 2009
    ..In patients with organic anejaculation but without SCI midodrine can reverse anejaculation in more than 50% of patients. Further studies are needed, however, for the evaluation of different treatment regimens in anejaculation therapy...
  12. ncbi A randomized, double-blind, placebo-controlled study of the efficacy and safety of bupropion for treating hypoactive sexual desire disorder in ovulating women
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Centre, Shahid Modarress Hospital, Shahid Beheshti University, Tehran, Iran
    BJU Int 106:832-9. 2010
    ..To compare the efficacy of sustained-release (SR) bupropion to placebo in treating hypoactive sexual desire disorder (HSDD) in ovulating women...
  13. ncbi The effects of intensive, long-term treadmill running on reproductive hormones, hypothalamus-pituitary-testis axis, and semen quality: a randomized controlled study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University MC, Tehran, Iran
    J Endocrinol 200:259-71. 2009
    ..These parameters improved to their pre-exercise level during the recovery period. Long-term strenuous treadmill exercises (overtraining syndrome) have a deleterious effect on reproduction...
  14. doi Evaluation of endocrine profile, hypothalamic-pituitary-testis axis and semen quality in multiple sclerosis
    M R Safarinejad
    Urology and Nephrology Research Centre, Shahid Beheshti University, Tehran, Iran
    J Neuroendocrinol 20:1368-75. 2008
    ..It appears that the damage to HPT axis is both in pituitary and testicular levels. Further studies are needed to better elucidate the underlying pathophysiology of HPT axis dysregulation...
  15. ncbi A double-blind placebo-controlled study of the efficacy and safety of pentoxifylline in early chronic Peyronie's disease
    Mohammad Reza Safarinejad
    Department of Urology, Shaheed Modarress Hospital, Shahid Beheshti University, Tehran, Iran
    BJU Int 106:240-8. 2010
    ..To analyse the safety and efficacy of pentoxifylline sustained-release (PTX-SR) treatment in patients with early chronic Peyronie's disease (PD)...
  16. doi Polymorphisms of the serotonin transporter gene and their relation to premature ejaculation in individuals from Iran
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University MC, Tehran, Iran
    J Urol 181:2656-61. 2009
    ....
  17. doi Analysis of association between the 5-HTTLPR and STin2 polymorphisms in the serotonin-transporter gene and clinical response to a selective serotonin reuptake inhibitor (sertraline) in patients with premature ejaculation
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Centre, Shahid Beheshti University MC, Tehran, Iran
    BJU Int 105:73-8. 2010
    ....
  18. doi Relationship between three polymorphisms of methylenetetrahydrofolate reductase (MTHFR C677T, A1298C, and G1793A) gene and risk of prostate cancer: a case-control study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University MC, Tehran, Iran
    Prostate 70:1645-57. 2010
    ..We hypothesized that genetic polymorphisms in methylenetetrahydrofolate reductase (MTHFR) gene are associated with prostate cancer risk...
  19. ncbi Comparison of dapoxetine versus paroxetine in patients with premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized study
    Mohammad Reza Safarinejad
    Urology Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Clin Neuropharmacol 29:243-52. 2006
    ..To compare the efficacy and safety of dapoxetine, paroxetine, and placebo for the oral pharmacotherapy of premature ejaculation...
  20. ncbi Female sexual dysfunction in a population-based study in Iran: prevalence and associated risk factors
    M R Safarinejad
    Urology Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Int J Impot Res 18:382-95. 2006
    ..05) menopause status (P<or=0.01) and spousal erectile dysfunction (P=0.01) were significantly associated with FSD. This study provides a quantitative estimate of the prevalence and the main risk factors for FSD in Iranian women...
  21. ncbi Salvage of sildenafil failures with cabergoline: a randomized, double-blind, placebo-controlled study
    M R Safarinejad
    Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Int J Impot Res 18:550-8. 2006
    ..001). Cabergoline is moderately effective salvage therapy for sildenafil nonresponse. Further studies with different dosages and treatment regimens are necessary to draw final conclusions on the efficacy of this drug in ED...
  22. ncbi Safety and efficacy of citalopram in the treatment of premature ejaculation: a double-blind placebo-controlled, fixed dose, randomized study
    M R Safarinejad
    Urology Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Int J Impot Res 18:164-9. 2006
    ..Further studies with different dosages and treatment regimens are necessary to draw final conclusions on the efficacy of this drug in PE and to prolong the efficacy...
  23. ncbi Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study
    Mohammad Reza Safarinejad
    Department of Urology, Urology Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Herb Pharmacother 5:1-11. 2005
    ..To determine the effects of therapy with Urtica dioica for symptomatic relief of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH)...
  24. ncbi Population-based screening for prostate cancer by measuring free and total serum prostate-specific antigen in Iran
    M R Safarinejad
    Urology Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Ann Oncol 17:1166-71. 2006
    ..To evaluate the natural background of prostate cancer in Iran a large population-based study of screening using total prostate-specific antigen (tPSA) and per cent free PSA (fPSA) as the initial test was performed...
  25. ncbi Safety and efficacy of tamsulosin in the treatment of painful ejaculation: a randomized, double-blind, placebo-controlled study
    M R Safarinejad
    Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Int J Impot Res 18:527-33. 2006
    ..8 and 1.6 to 1.9 and 1.7, for tamsulosin and placebo, respectively (P=0.08). Mean number of adverse events was 11 for tamsulosin and 5 for placebo (P<0.05). Tamsulosin is no better than placebo in improvement of PE as a sole entity...
  26. ncbi Safety and efficacy of tramadol in the treatment of premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized study
    Mohammad Reza Safarinejad
    Urology Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Clin Psychopharmacol 26:27-31. 2006
    ..To evaluate the efficacy and safety of a new serotonergic centrally acting drug tramadol in delaying ejaculation in patients with premature ejaculation...
  27. doi Safety and efficacy of sildenafil citrate in treating erectile dysfunction in patients with combat-related post-traumatic stress disorder: a double-blind, randomized and placebo-controlled study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Centre, Shahid Beheshti University Research Centre, Tehran, Iran
    BJU Int 104:376-83. 2009
    ..To evaluate the safety and efficacy of sildenafil citrate for treating erectile dysfunction (ED) in patients with combat-related post-traumatic stress disorder (PTSD)...
  28. ncbi Polymorphisms in aryl hydrocarbon receptor gene are associated with idiopathic male factor infertility
    Mohammad Reza Safarinejad
    1Clinical Center for Urological Disease Diagnosis and Private Clinic Specialized in Urological and Andrological Genetics, Tehran, Iran
    Reprod Sci 20:1423-32. 2013
    ..62, 95% CI: 2.77-52.74; P = .00001). Homozygosity for the rs2066853 A allele and rs2282885 C allele decreases and increases the risk of developing male infertility, respectively. ..
  29. doi The effect of coenzyme Q₁₀ supplementation on partner pregnancy rate in infertile men with idiopathic oligoasthenoteratozoospermia: an open-label prospective study
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis, Private Clinic Specialized in Urological and Andrological Genetics, PO Box 19395 1849, Tehran, Iran
    Int Urol Nephrol 44:689-700. 2012
    ..In present study, we evaluated the effects of coenzyme CoQ(10) supplementation on semen parameters and pregnancy rates in infertile men with idiopathic OAT...
  30. ncbi Sperm DNA damage and semen quality impairment after treatment with selective serotonin reuptake inhibitors detected using semen analysis and sperm chromatin structure assay
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University, Tehran, Iran
    J Urol 180:2124-8. 2008
    ..Semen parameters and sperm DNA were evaluated in patients receiving selective serotonin reuptake inhibitors...
  31. ncbi Glutathione S-transferase polymorphisms (GSTM1, GSTT1, GSTP1) and male factor infertility risk: a pooled analysis of studies
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis and Private Clinic Specialized in Urological and Andrological Genetics, Tehran, Iran
    Urol J 9:541-8. 2012
    ..To determine the role of glutathione S-transferases (GSTs; GSTM1, GSTT1, and GSTP1) gene polymorphisms in susceptibility to male factor infertility...
  32. doi Evaluation of endocrine profile and hypothalamic-pituitary-testis axis in selective serotonin reuptake inhibitor-induced male sexual dysfunction
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University MS, Tehran, Iran
    J Clin Psychopharmacol 28:418-23. 2008
    ..To evaluate endocrine profile and hypothalamic-pituitary-testis (HPT) axis in male depressed patients with selective serotonin reuptake inhibitor (SSRI)-induced sexual dysfunction (SDF)...
  33. doi The effects of opiate consumption on serum reproductive hormone levels, sperm parameters, seminal plasma antioxidant capacity and sperm DNA integrity
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis and Private Clinic Specialized in Urological and Andrological Genetics, Tehran, Iran
    Reprod Toxicol 36:18-23. 2013
    ..Opiate consumption has significant adverse effects on semen quality. In cases of unexplained infertility in men, opium consumption should be considered as a possible factor...
  34. ncbi Salvage of sildenafil failures with bremelanotide: a randomized, double-blind, placebo controlled study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shaheed Modarress Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Urol 179:1066-71. 2008
    ..We evaluated the safety and efficacy of intranasal bremelanotide in men with erectile dysfunction who did not respond to sildenafil...
  35. doi Effects of the reduced form of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility: a double-blind, placebo controlled, randomized study
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis, Tehran, Iran
    J Urol 188:526-31. 2012
    ..We investigated the effects of the administration of ubiquinol (a reduced form of coenzyme Q(10)) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasthenoteratozoospermia...
  36. doi G-protein β3 subunit gene 825C/T polymorphism and its association with the presence, severity, and duration of vasculogenic erectile dysfunction
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis and Private Clinic Specialized in Urological and Andrological Genetics, Tehran, Iran
    Fertil Steril 99:69-75. 2013
    ..To investigate the association between G-protein β3 (GNB3) subunit gene 825C/T polymorphism and vasculogenic ED (VED)...
  37. ncbi G Protein β3 subunit gene C825T polymorphism and its association with the presence and clinicopathological characteristics of prostate cancer
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis and Private Clinic Specialized in Urological and Andrological Genetics, Tehran, Iran
    J Urol 188:287-93. 2012
    ..This splice variant is associated with various malignant diseases. We investigated the possible association of GNB3 gene polymorphism with prostate cancer and its clinicopathological characteristics...
  38. doi Opium consumption is negatively associated with serum prostate-specific antigen (PSA), free PSA, and percentage of free PSA levels
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis, Tehran, Iran
    J Addict Med 7:58-65. 2013
    ..06, 95% CI, -0.04 to -0.08, P = 0.0001; and r = -0.05, 95% CI, -0.03 to -0.07, P = 0.0001, respectively). Opium consumption is independently and negatively associated with serum tPSA, fPSA, and % fPSA levels...
  39. doi Estrogen receptors alpha (rs2234693 and rs9340799), and beta (rs4986938 and rs1256049) genes polymorphism in prostate cancer: evidence for association with risk and histopathological tumor characteristics in Iranian men
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis and Private Clinic Specialized in Urological and Andrological Genetics, Tehran, Iran
    Mol Carcinog 51:E104-17. 2012
    ..05 pg/ml). Genotypes which confer susceptibility for developing PCa, accompanied with lowest serum levels of free E2. In the Iranian population, genetic polymorphisms of the ER-α and ER-β genes may be involved in the etiology of PCa...
  40. doi Reproductive hormones and hypothalamic-pituitary-ovarian axis in female patients with homozygous beta-thalassemia major
    Mohammad Reza Safarinejad
    Department of Urology, Urology and Nephrology Research Centre, Shahid Beheshti University MC, Tehran, Iran
    J Pediatr Hematol Oncol 32:259-66. 2010
    ..Our aims were to evaluate reproductive hormones, hypothalamic-pituitary-ovarian axis, and fertility in female patients with hbeta-TM...
  41. doi Evaluation of semen variables, sperm chromosomal abnormalities and reproductive endocrine profile in patients with chronic hepatitis C
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Faculty of Medicine, Shahid Beheshti University MC, Tehran, Iran
    BJU Int 105:79-86. 2010
    ..To evaluate reproductive endocrine profile, sperm chromosomal abnormalities, and semen quality in patients with chronic hepatitis C...
  42. doi Relationship between genetic polymorphisms of methylenetetrahydrofolate reductase (C677T, A1298C, and G1793A) as risk factors for idiopathic male infertility
    Mohammad Reza Safarinejad
    Private Practice of Urology and Andrology, POBox 19395 1849, Tehran, Iran
    Reprod Sci 18:304-15. 2011
    ..We determined associations between 3 MTHFR gene polymorphisms (C677T, A1298C, and G1793A), serum folate, and total homocysteine (tHcy) levels, with male fertility status and semen parameters...
  43. doi Association of the T-786C, G894T and 4a/4b polymorphisms of the endothelial nitric oxide synthase gene with vasculogenic erectile dysfunction in Iranian subjects
    Mohammad Reza Safarinejad
    Private Practice of Urology and Andrology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran
    BJU Int 107:1994-2001. 2011
    ..To investigate the association of the T-786C, G894T and variable number of tandem repeats (VNTRs) in intron 4 (a/b) polymorphisms of the eNOS gene in Iranian subjects with vasculogenic erectile dysfunction (ED)...
  44. doi Effects of EPA, γ-linolenic acid or coenzyme Q10 on serum prostate-specific antigen levels: a randomised, double-blind trial
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis and Private Clinic Specialized in Urological and Andrological Genetics, PO Box 19395 1849, Tehran, Iran
    Br J Nutr 110:164-71. 2013
    ..The present study demonstrates that dietary supplements containing EPA, GLA or CoQ10 may significantly affect serum PSA levels...
  45. ncbi Sexual function of primiparous women after elective cesarean section and normal vaginal delivery
    Ladan Hosseini
    School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
    Urol J 9:498-504. 2012
    ..To compare sexual function between two groups of women who had normal vaginal delivery (NVD) and planned cesarean section (PCS)...
  46. ncbi Infertility among couples in a population-based study in Iran: prevalence and associated risk factors
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Int J Androl 31:303-14. 2008
    ..Yet, further studies on the cause of primary and secondary infertility and geographical variations in the incidence and prevalence of infertility in Iran are needed...
  47. doi Prevalence of benign prostatic hyperplasia in a population-based study in Iranian men 40 years old or older
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, P O Box 19395 1849, Tehran, Iran
    Int Urol Nephrol 40:921-31. 2008
    ..03), and marital status (P = 0.01). The prevalence of BPH is relatively high in Iran. The provided bothersome due to BPH did not correlate to symptom severity and should be considered independently in clinical decision-making...
  48. ncbi Endocrine profiles and semen quality in spinal cord injured men
    A R Naderi
    Department of Urology, Military University of Medical Sciences, Tehran, Iran
    Clin Endocrinol (Oxf) 58:177-84. 2003
    ..To evaluate the hypothalamic-pituitary-testis (HPT) axis, endocrine profiles and semen quality in men with spinal cord injury (SCI)...
  49. doi Comparison of macroscopic one-layer over number 1 nylon suture vasovasostomy with the standard two-layer microsurgical procedure
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis and Private Clinic Specializing in Urological and Andrological Genetics, Tehran, Iran
    Hum Fertil (Camb) 16:194-9. 2013
    ..To compare the outcomes of macroscopic one-layer vasovasostomy (MOLVV) with those of two-layer microsurgical vasovasostomy (TLMVV)...
  50. doi Quality of life and sexual functioning in young women with early-stage breast cancer 1 year after lumpectomy
    Mohammad Reza Safarinejad
    Clinical Centre for Urological and Gynecological Disease Diagnosis, Tehran, Iran
    Psychooncology 22:1242-8. 2013
    ..This study evaluated sexual functioning, quality of life, and self-esteem in young women with early-stage BC...
  51. ncbi Comparison of vitamin E and propionyl-L-carnitine, separately or in combination, in patients with early chronic Peyronie's disease: a double-blind, placebo controlled, randomized study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Faculty of Medicine, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Urol 178:1398-403; discussion 1403. 2007
    ..We compared the efficacy and safety of oral vitamin E and propionyl-L-carnitine, separately or in combination, for the treatment of Peyronie's disease...
  52. doi Evaluation of the safety and efficacy of sildenafil citrate for erectile dysfunction in men with multiple sclerosis: a double-blind, placebo controlled, randomized study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University, Tehran, Iran
    J Urol 181:252-8. 2009
    ..We evaluated the safety and efficacy of sildenafil citrate for treating erectile dysfunction in patients with multiple sclerosis...
  53. doi A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasthenoteratozoospermia
    Mohammad Reza Safarinejad
    Private Practice of Urology and Andrology, Tehran, Iran
    Phytother Res 25:508-16. 2011
    ..If medical professionals want to prescribe herbal remedies for male infertility, previous rigorous scientific investigations, documenting their safety and efficacy are required...
  54. doi Effect of pentoxifylline on semen parameters, reproductive hormones, and seminal plasma antioxidant capacity in men with idiopathic infertility: a randomized double-blind placebo-controlled study
    Mohammad Reza Safarinejad
    Private Practice of Urology and Andrology, P O Box 19395 1849, Tehran, Iran
    Int Urol Nephrol 43:315-28. 2011
    ..To determine the safety and efficacy of oral pentoxifylline (PTX) administration in improving semen parameters in infertile men with idiopathic OAT...
  55. ncbi Testicular effect of mustard gas
    M R Safarinejad
    Department of Urology, Military University of Medical Sciences, Tehran, Iran
    Urology 58:90-4. 2001
    ..Testicular biopsy showed selective atrophy of the germinal epithelium, intact Sertoli cells, and normal-appearing Leydig cells. CONCLUSIONS: Mustard gas can cause defective spermatogenesis years after exposure...
  56. doi Association between polymorphisms in osteopontin gene (SPP1) and first episode calcium oxalate urolithiasis
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis and Private Clinic Specialized in Urological and Andrological Genetics, P O Box 19395 1849, Tehran, Iran
    Urolithiasis 41:303-13. 2013
    ..Of 28 constructed haplotypes, 6 demonstrated significant association with COU risk. There was no sex difference in the obtained results. The SPP1 gene polymorphisms are associated with the COU susceptibility. ..
  57. doi Genetic susceptibility of methylenetetrahydrofolate reductase (MTHFR) gene C677T, A1298C, and G1793A polymorphisms with risk for bladder transitional cell carcinoma in men
    Mohammad Reza Safarinejad
    Private Practice of Urology and Andrology, PO Box 19395 1849, Tehran, Iran
    Med Oncol 28:S398-412. 2011
    ..01). There was no significant correlation between serum levels of tHcy and folate and bladder cancer risk. Further studies in larger samples size and different ethnicity are required to confirm our findings...
  58. doi Association of the (TAAAA)n repeat and Asp327Asn polymorphisms in the sex hormone-binding globulin (SHBG) gene with idiopathic male infertility and relation to serum SHBG concentrations
    Mohammad Reza Safarinejad
    Private Practice of Urology and Andrology, Tehran, Iran
    J Steroid Biochem Mol Biol 123:37-45. 2011
    ..Multicenter large scale studies are warranted to better elucidate the role of SHBG gene polymorphism in male infertility...
  59. ncbi Adult urolithiasis in a population-based study in Iran: prevalence, incidence, and associated risk factors
    Mohammad Reza Safarinejad
    Department of Urology, Urology Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Urol Res 35:73-82. 2007
    ..Further studies are warranted in order to determine the incidence and prevalence of urolithiasis in different ethnic groups...
  60. ncbi Is bowel preparation necessary before kidney-ureter-bladder radiography and intravenous urography?
    Farid Dadkhah
    Department of Urology, Shahid Modarress Hospital, Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Urol J 9:600-5. 2012
    ..To assess whether bowel preparation prior to kidney-ureter-bladder (KUB) radiography and intravenous urography (IVU) are of value in improving visualization of the urinary system...
  61. doi Penile vascular indices in surgically treated and conservatively treated penile fracture: does conventional immediate repair matter?
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis and Private Clinic Specialized in Urological and Andrological Genetics, P O Box 19395 1849, Tehran, Iran
    Int Urol Nephrol 44:1631-40. 2012
    ..To investigate the impact of immediate surgical repair and conservative treatment of penile fracture (PF) on penile vascular indices...
  62. doi Relationship between premature ejaculation and genetic polymorphisms of the dopamine transporter gene (SLC6A3)
    Mohammad Reza Safarinejad
    Private Practice of Urology and Andrology, Tehran, Iran
    BJU Int 108:292-6. 2011
    ....
  63. doi Efficacy and safety of omega-3 for treatment of early-stage Peyronie's disease: A prospective, randomized, double-blind placebo-controlled study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University, Tehran, Iran
    J Sex Med 6:1743-54. 2009
    ..However, there is a lack of evidence to show a clear clinical benefit of omega-3 in patients with PD...
  64. ncbi The epidemiology of adult chronic kidney disease in a population-based study in Iran: prevalence and associated risk factors
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Centre, Shahid Beheshti University MC, Tehran, Iran
    J Nephrol 22:99-108. 2009
    ..The prevalence of chronic kidney disease (CKD) varies greatly between countries. In a community-based study, our aims were to determine the prevalence and associated risk factors of adult CKD in Iran...
  65. doi Evaluation of the safety and efficacy of bremelanotide, a melanocortin receptor agonist, in female subjects with arousal disorder: a double-blind placebo-controlled, fixed dose, randomized study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Sex Med 5:887-97. 2008
    ..Sexual arousal disorder affects about 30% of women worldwide and there are no effective drug treatments for the disorder...
  66. doi Evaluation of semen quality, endocrine profile and hypothalamus-pituitary-testis axis in male patients with homozygous beta-thalassemia major
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University M C, Tehran, Iran
    J Urol 179:2327-32. 2008
    ..The endocrine profile, hypothalamus-pituitary-testis axis and semen quality were evaluated in male patients with homozygous beta-thalassemia major...
  67. doi The influence of promoter -202 A/C polymorphism (rs2854744) of the IGFBP-3 gene on erectile dysfunction risk and serum levels of IGF-I and IGFBP-3
    Mohammad Reza Safarinejad
    Clinical Center for Urological Disease Diagnosis and Private Clinic Specialized in Urological and Andrological Genetics, Tehran, Iran
    J Urol 189:374-9. 2013
    ..We studied whether the IGFBP-3 gene polymorphism rs2854744 is associated with erectile dysfunction...
  68. ncbi Combination chemotherapy with docetaxel, estramustine and suramin for hormone refractory prostate cancer
    Mohammad Reza Safarinejad
    Department of Urology, Urology Nephrology Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Urol Oncol 23:93-101. 2005
    ..To investigate more effective chemotherapy against hormone refractory prostate cancer (HRPC) with the combination of estramustine (EM), docetaxel, and suramin...
  69. ncbi Level of injury and hormone profiles in spinal cord-injured men
    M R Safarinejad
    Department of Urology, Division of Urology and Renal Transplantation, Military University of Medical Sciences, Air Force Hospital, Tehran, Iran
    Urology 58:671-6. 2001
    ..CONCLUSIONS: The results of our study indicate that subjects with SCI have an altered central neurotransmitter tone, and the likelihood of these abnormalities (hypogonadotropism) are higher in men with low thoracic SCI...
  70. ncbi Atorvastatin improves the response to sildenafil in hypercholesterolemic men with erectile dysfunction not initially responsive to sildenafil
    F Dadkhah
    Department of Urology, Shahid Modarress Hospital, Shahid Beheshti University, MC, Tehran, Iran
    Int J Impot Res 22:51-60. 2010
    ..Further investigation is needed to test the usefulness of long-term atorvastatin administration to restore erectile function in sildenafil nonresponders...
  71. ncbi Prevalence and risk factors for erectile dysfunction in a population-based study in Iran
    M R Safarinejad
    Department of Urology, Military University of Medical Sciences, Tehran, Iran
    Int J Impot Res 15:246-52. 2003
    ..71, 95% CI, 2.51-6.76 and OR 2.80, 95% CI, 1.47-4.32, respectively). This study provides a quantitative estimate of the prevalence and main risk factors for ED in Iranian men...
  72. doi Influence of opioid consumption on serum prostate-specific antigen levels in men without clinical evidence of prostate cancer
    Seyed Yousef Hosseini
    Urology and Nephrology Research Center, Department of Urology, Shahid Modarress Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Urology 80:169-73. 2012
    ..To determine the effect of opioid consumption on the serum prostate-specific antigen (PSA) level...
  73. doi The association between bladder cancer and a single nucleotide polymorphism (rs2854744) in the insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) gene
    Mohammad Reza Safarinejad
    Private Practice of Urology and Andrology, Tehran, Iran
    Arch Toxicol 85:1209-18. 2011
    ..10, P = 0.87). Genetic polymorphism of the IGFBP-3 gene may be involved in the etiology of bladder TCC, and our results need further confirmation by larger studies...
  74. ncbi Antisperm antibodies in hydroceles before and after surgery
    Mohammad Reza Safarinejad
    Department of Urology, Military University of Medical Sciences, Tehran, Iran
    Fertil Steril 79:457-8. 2003
  75. doi The effect of the mode of delivery on the quality of life, sexual function, and sexual satisfaction in primiparous women and their husbands
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University, Tehran, Iran
    J Sex Med 6:1645-67. 2009
    ..Exploring the hypothesis that "sexual function" is associated with mode of delivery is important, because sexual health is an integral part of general health...
  76. ncbi Penile revascularization for erectile dysfunction: a systematic review and meta-analysis of effectiveness and complications
    Ali Reza Babaei
    Department of Plastic Surgery, AJA University of Medical Sciences, Tehran, Iran
    Urol J 6:1-7. 2009
    ..We aimed to determine the subjective and objective outcomes of PR surgery in patients with arteriogenic ED...
  77. ncbi Opium consumption and risk of bladder cancer: A case-control analysis
    Seyyed Yousof Hosseini
    Departments of Urology, Shaheed Modarress Hospital, and Urology and Nephrology Research Center, Shahid Beheshti University MC, Teheran, Iran
    Urol Oncol 28:610-6. 2010
    ..We evaluated the relationship between opium consumption and bladder cancer (BC) in a case-control study of an Iranian population...
  78. ncbi Modified ureteroneocystostomy in kidney transplantation to facilitate endoscopic management of subsequent urological complications
    Farid Dadkhah
    Department of Urology, Shaheed Modarress Hospital, Shahid Beheshti University MC, Tehran, Iran
    Int Urol Nephrol 42:285-93. 2010
    ..Endourology has allowed for a less-invasive approach to dealing with these transplant complications. Access to the upper urinary tract in traditionally anterior extravesical ureteroneocystostomy is usually difficult if not impossible...
  79. doi Safety and efficacy of sorafenib in patients with castrate resistant prostate cancer: a Phase II study
    Mohammad Reza Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University MS, Teheran, Iran
    Urol Oncol 28:21-7. 2010
    ..We determined the safety and efficacy of sorafenib in patients with castrate resistant prostate cancer (CRPC)...
  80. doi Prevalence of the overactive bladder among Iranian women based on the International Continence Society definition: a population-based study
    Mohammad Reza Safarinejad
    Urology Nephrology Research Center, Shaheed Beheshti University MS, Tehran, Iran
    Int Urol Nephrol 41:35-45. 2009
    ..Our results reveal that OAB is a highly prevalent condition among Iranian women and that is has a serious impact on quality of life and sexual function...
  81. ncbi Incidental prostatic adenocarcinoma in patients with PSA less than 4 ng/mL undergoing radical cystoprostatectomy for bladder cancer in Iranian men
    S Y Hosseini
    Urology and Nephrology Research Center, Shaheed Modarress and Shaheed Labbafinejad Hospitals, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Int Braz J Urol 33:167-73; discussion 173-5. 2007
    ..To assess the incidence of prostate adenocarcinoma in patients undergoing radical cystoprostatectomy due to bladder cancer in Iranian men...
  82. ncbi Therapeutic effects of colchicine in the management of Peyronie's disease: a randomized double-blind, placebo-controlled study
    M R Safarinejad
    Department of Urology, Medicine Faculty, Military University of Medical Sciences, Tehran, Iran
    Int J Impot Res 16:238-43. 2004
    ..Colchicine is no better than placebo in improvement of pain, curvature angle, or plaque size in patients with Peyronie's disease...
  83. ncbi Safety and efficacy of venlafaxine in the treatment of premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomised study
    M R Safarinejad
    Urology and Nephrology Research Center, Shahid Beheshti University MS, Tehran, Iran
    Andrologia 40:49-55. 2008
    ..07). Mean number of adverse events was 32 for venlafaxine and 8 for placebo (P = 0.02). Venlafaxine is not better than placebo in treatment of PE...
  84. ncbi Effects of varicocele repair on spontaneous first trimester miscarriage: a randomized clinical trial
    Mandana Mansour Ghanaie
    Urology Research Center, Guilan University of Medical Sciences, Rasht, Iran
    Urol J 9:505-13. 2012
    ..To evaluate the effects of varicocelectomy on semen parameters, pregnancy rates, and live birth in couples with first term recurrent miscarriage...
  85. ncbi The frequency of prostatic involvement in radical cystectomy specimens for transitional cell carcinoma of the bladder
    Abbas Basiri
    Urology and Nephrology Research Center, Department of Urology, Shaheed Labbafinejad Hospital, Shahid Beheshti University MS, Tehran, Iran
    J Pak Med Assoc 58:479-81. 2008
    ..To evaluate the frequency of prostatic involvement in pathologic samples of the patients who had undergone radical cystectomy due to transitional cell carcinoma (TCC) of the bladder...
  86. ncbi Penile replantation, science or myth? A systematic review
    Ali Reza Babaei
    Urology and Nephrology Research Center, Shaheed Beheshti Medical University, 19395 1849 Tehran, Iran
    Urol J 4:62-5. 2007
    ..The surgical technique used for repair has been modified and refined. Our aim was to assess the effects of several interventions and management for amputated penis after replantation...
  87. ncbi Penile reconstruction: evaluation of the most accepted techniques
    Alireza Babaei
    Department of Plastic Surgery, AJA University of Medical Sciences, Tehran, Iran
    Urol J 7:71-8. 2010
    ..The objective of this review was to determine the efficacy, advantages and disadvantages of the most popular penile reconstruction (PR) and phallus construction techniques...
  88. ncbi Ocular injuries caused by mustard gas: diagnosis, treatment, and medical defense
    M R Safarinejad
    Department of Ophthalmology, Military University of Medical Sciences and Air Force Hospitals, Tehran, Iran
    Mil Med 166:67-70. 2001
    ..In conclusion, the eye is the organ most sensitive to sulfur mustard vapor. Ocular injuries generally heal completely. In severe cases, blindness may occur. The need for corneal transplantation is rare...
  89. ncbi Therapeutic effects of high-dose isoxsuprine in the management of mixed-type impotence
    M R Safarinejad
    Department of Urology, Military University of Medical Sciences, Tehran, Iran
    Urology 58:95-7. 2001
    ..To determine the effectiveness and safety of high-dose isoxsuprine for the treatment of mixed-type erectile dysfunction...
  90. pmc Safety and efficacy of tramadol in the treatment of idiopathic detrusor overactivity: a double-blind, placebo-controlled, randomized study
    M R Safarinejad
    Urology Nephrology Research Centre, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Br J Clin Pharmacol 61:456-63. 2006
    ..To evaluate the efficacy and safety of tramadol in patients with idiopathic detrusor overactivity (IDO)...
  91. ncbi Editorial independence: surrounding controversies
    Mohammad Reza Safarinejad
    Urol J 4:191. 2007