Research Topics
| M SayyahSummaryAffiliation: Pasteur Institute of Iran Country: Iran Publications
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Detail Information
Publications
Anti-epileptogenic effect of beta-carotene and vitamin A in pentylenetetrazole-kindling model of epilepsy in miceMohammad Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Pasteur Avenue, Tehran 13164, Iran
Epilepsy Res 63:11-6. 2005..Non-genomic and genomic mechanisms could be involved in the anti-epileptogenic effect of Vit A and beta-carotene...- Anticonvulsant activity of the leaf essential oil of Laurus nobilis against pentylenetetrazole- and maximal electroshock-induced seizuresM Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Tehran
Phytomedicine 9:212-6. 2002..This effect seems to be related in part to cineol, eugenol and methyleugenol. Although the essential oil had an acceptable acute toxicity, further studies are required before any absolute conclusions can be drawn... - Analgesic and anti-inflammatory activity of Lactuca sativa seed extract in ratsMohammad Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Tehran, Iran
J Ethnopharmacol 92:325-9. 2004..No abnormal behavior and lethality was observed by the extract up to 6 g/kg. Preliminary phytochemical analysis showed the presence of triterpenoids, saponins and simple phenols in the extract... - Anticonvulsant activity of Heracleum persicum seedMohammad Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Tehran, Iran
J Ethnopharmacol 98:209-11. 2005..Preliminary phytochemical analysis showed the presence of alkaloids, terpenoids, triterpenes and steroids in the extract. The observed pharmacological effects could be due to alkaloids, terpenoids and triterpenes present in the plant... - Intra-amygdala all-trans retinoic acid inhibits amygdala-kindled seizures in ratsMohammad Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Pasteur Avenue, Tehran 1316943551, Iran
Epilepsy Res 75:97-103. 2007..ATRA administered intra-BLA prevented the proconvulsant effect of TMA. The reduction of gap junctional conductance might be involved in the observed anticonvulsant effect of ATRA... - Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oilMohammad Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Tehran
J Ethnopharmacol 94:283-7. 2004..8%), alpha-terpinolene (0.5%), bornyl acetate (0.5%) and bicyclogermacrene (0.5%) as the main components. The observed anticonvulsant and sedative effects could be related to the presence of monoterpenoids in the essential oil... - Lipopolysaccharide retards development of amygdala kindling but does not affect fully-kindled seizures in ratsMohammad Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Pasteur Avenue, Tehran 13164, Iran
Epilepsy Res 57:175-80. 2003..This antiepileptogenic effect could be due to the release of inflammatory mediators from microglia and the related morphological and functional changes in synaptic neurotransmission... - The bacterial endotoxin lipopolysaccharide enhances seizure susceptibility in mice: involvement of proinflammatory factors: nitric oxide and prostaglandinsM Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Pasteur Avenue, Tehran 13164, Iran
Neuroscience 122:1073-80. 2003..These results indicate that NO, PGs and endogenous opioid peptides seem to be involved in LPS-induced decrease in seizure threshold... - Evaluation of the anticonvulsant activity of the seed acetone extract of Ferula gummosa Boiss. against seizures induced by pentylenetetrazole and electroconvulsive shock in miceMohammad Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Tehran, Iran
J Ethnopharmacol 82:105-9. 2002..The acceptable acute toxicity of the extract recommends further studies to determine the mechanism(s) and compound(s) involved in the anticonvulsant activity... - Analgesic and anti-inflammatory activity of the leaf essential oil of Laurus nobilis LinnM Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Pasteur Avenue, Tehran, Iran
Phytother Res 17:733-6. 2003..Present results make the essential oil worthy of further investigations... - Pharmacokinetics, efficacy, and safety of Iminoral compared with Neoral in healthy volunteers and renal transplant recipientsM Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Tehran, Iran
Transplant Proc 39:1214-8. 2007..This study sought to evaluate the bioequivalence of Iminoral (test) versus Neoral (reference) in healthy volunteers, as well as safety and efficacy of Iminoral treatment in renal transplant recipients following conversion from Neoral... - Antiepileptogenic and anticonvulsant activity of interleukin-1 beta in amygdala-kindled ratsM Sayyah
Department of Physiology and Pharmacology, Institute Pasteur of Iran, Tehran, Iran
Exp Neurol 191:145-53. 2005..Although most of the previous studies indicate a proconvulsant or convulsant property of IL-1, our results support a protective and antiepileptogenic role of IL-1beta... - Eugenol depresses synaptic transmission but does not prevent the induction of long-term potentiation in the CA1 region of rat hippocampal slicesA Ardjmand
Department of Physiology, School of Medical Sciences, Tarbiat Modarres University, Tehran, Iran
Phytomedicine 13:146-51. 2006..Eugenol had no effect on PBs-induced LTP of PS. It is concluded that while eugenol depresses synaptic transmission it does not affect the ability of CA1 synapses for tetanus-induced LTP and plasticity... - Anticonvulsant effect of flutamide on seizures induced by pentylenetetrazole: involvement of benzodiazepine receptorsAbolhassan Ahmadiani
Neuroscience Center, Shaheed Beheshti University of Medical Sciences, Tehran 13164, Iran
Epilepsia 44:629-35. 2003..8 mg/kg was obtained for Flut. CONCLUSIONS: Flut both blocks PTZ-induced clonic seizures and elevates the threshold of PTZ or bicuculline-induced clonic seizures, through interaction with BZD receptors... - A preliminary randomized double blind clinical trial on the efficacy of aqueous extract of Echium amoenum in the treatment of mild to moderate major depressionMehdi Sayyah
Department of Psychiatry, Psychiatric and Clinical Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran
Prog Neuropsychopharmacol Biol Psychiatry 30:166-9. 2006..In this study, efficacy of an aqueous extract of E. amoenum in patients with mild to moderate major depressive disorder (a score > or =18 on the Hamilton depression rating scale) was evaluated...