A R Dehpour

Summary

Affiliation: National Research Center for Genetic Engineering and Biotechnology
Country: Iran

Publications

  1. ncbi Effect of chronic lithium administration on endothelium-dependent relaxation in rat aorta
    A R Dehpour
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    Clin Exp Pharmacol Physiol 27:55-9. 2000
  2. ncbi Subsensitivity to opioids is receptor-specific in isolated guinea pig ileum and mouse vas deferens after obstructive cholestasis
    A R Dehpour
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    J Pharmacol Exp Ther 293:946-51. 2000
  3. ncbi Time-dependent reduction of acetylcholine-induced relaxation in aortic rings of cholestatic rats
    H Rastegar
    Department of Pharmacology, School of Medicine, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Pharmacol Res 44:519-25. 2001
  4. ncbi Mesenteric vascular bed responsiveness in bile duct-ligated rats: roles of opioid and nitric oxide systems
    K Namiranian
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O.Box 13145-784, Tehran, Iran
    Eur J Pharmacol 423:185-93. 2001
  5. ncbi Endogenous nitric oxide modulates naloxone-precipitated withdrawal signs in a mouse model with acute cholestasis
    A R Dehpour
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    Behav Pharmacol 9:77-80. 1998
  6. ncbi Alpha 2-adrenoceptor and NO mediate the opioid subsensitivity in isolated tissues of cholestatic animals
    S Demehri
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145-784, Tehran, Iran
    Auton Autacoid Pharmacol 23:201-7. 2003
  7. ncbi Inhibition by L-NA, a nitric oxide synthase inhibitor, of naloxone-precipitated withdrawal signs in a mouse model of cholestasis
    P Ghafourifar
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    Life Sci 60:PL 265-70. 1997
  8. ncbi Effect of aminoguanidine in sperm DNA fragmentation in varicocelized rats: role of nitric oxide
    M Abbasi
    Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Iran
    Reprod Sci 18:545-50. 2011
  9. ncbi Clonidine attenuates naloxone-induced opioid-withdrawal syndrome in cholestatic mice
    A R Dehpour
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Pharmacol Toxicol 89:129-32. 2001
  10. ncbi Preconditioning of the rat random-pattern skin flap: modulation by opioids
    S Kiumehr
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran
    Br J Plast Surg 58:58-64. 2005

Collaborators

  • P Ghafourifar
  • A Ahmadiani
  • N Mirazi
  • K P Moore
  • M Ghazi-Khansari
  • A Nahavandi
  • K Amirshahrokhi
  • M Abbasi
  • M Ghasemi
  • H Homayoun
  • K Namiranian
  • H Rastegar
  • F Abolhassani
  • R Alizadeh
  • F Amidi
  • S Demehri
  • A R Mani
  • S Ejtemaei Mehr
  • H Sadeghipour
  • S Kiumehr
  • H Honar
  • S E Mehr
  • F Roushanzamir
  • M Samini
  • M Jorjani
  • M Shirazi
  • S Fazelipour
  • G Hassanzadeh
  • Kashani I Ragerdi
  • Y Hoshino
  • E Sato
  • M Raza
  • H Shafaroodi
  • B G Nezami
  • A R Hajrasouliha
  • S Tavakoli
  • T Gholipour
  • M Nobakht
  • M A Mohagheghi
  • S Amanpour
  • S Rabbani
  • M R Ebrahimkhani
  • K Riazi
  • N Rashidi
  • S Khavandgar
  • S A Gaskari
  • A H Mani
  • M Khosrowshahi

Detail Information

Publications20

  1. ncbi Effect of chronic lithium administration on endothelium-dependent relaxation in rat aorta
    A R Dehpour
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    Clin Exp Pharmacol Physiol 27:55-9. 2000
    ..6. These data support evidence for a possible increase in endothelium-dependent relaxation induced by ACh during long-term administration of lithium in rat aortic rings...
  2. ncbi Subsensitivity to opioids is receptor-specific in isolated guinea pig ileum and mouse vas deferens after obstructive cholestasis
    A R Dehpour
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    J Pharmacol Exp Ther 293:946-51. 2000
    ..Significant accumulation of endogenous opioids in plasma of cholestatic animals has been shown in several studies and this may account for a significant development of subsensitivity to inhibitory effects of opioid agonists...
  3. ncbi Time-dependent reduction of acetylcholine-induced relaxation in aortic rings of cholestatic rats
    H Rastegar
    Department of Pharmacology, School of Medicine, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Pharmacol Res 44:519-25. 2001
    ....
  4. ncbi Mesenteric vascular bed responsiveness in bile duct-ligated rats: roles of opioid and nitric oxide systems
    K Namiranian
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O.Box 13145-784, Tehran, Iran
    Eur J Pharmacol 423:185-93. 2001
    ..This study also provided evidence for the involvement of increased opioidergic tone and NO overproduction in cholestasis-induced vascular hyporesponsiveness...
  5. ncbi Endogenous nitric oxide modulates naloxone-precipitated withdrawal signs in a mouse model with acute cholestasis
    A R Dehpour
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    Behav Pharmacol 9:77-80. 1998
    ..The results of this study support the involvement of the L-arginine/nitric oxide pathway in the opioidergic-dependent manifestation of cholestasis in an animal model...
  6. ncbi Alpha 2-adrenoceptor and NO mediate the opioid subsensitivity in isolated tissues of cholestatic animals
    S Demehri
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145-784, Tehran, Iran
    Auton Autacoid Pharmacol 23:201-7. 2003
    ....
  7. ncbi Inhibition by L-NA, a nitric oxide synthase inhibitor, of naloxone-precipitated withdrawal signs in a mouse model of cholestasis
    P Ghafourifar
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    Life Sci 60:PL 265-70. 1997
    ..The results of this study support evidence for the involvement of the L-arg-nitric oxide pathway in opioidergic-dependent manifestation of cholestasis in an animal model...
  8. ncbi Effect of aminoguanidine in sperm DNA fragmentation in varicocelized rats: role of nitric oxide
    M Abbasi
    Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Iran
    Reprod Sci 18:545-50. 2011
    ..The aim of this study was to determine the effects of AG on sperm chromatin in varicocelized rats...
  9. ncbi Clonidine attenuates naloxone-induced opioid-withdrawal syndrome in cholestatic mice
    A R Dehpour
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Pharmacol Toxicol 89:129-32. 2001
    ..before clonidine blocked this ameliorative effect of clonidine. The results of this study support the evidence for involvement of the alpha2-adrenoceptors in the withdrawal syndrome of cholestasis in a mouse model...
  10. ncbi Preconditioning of the rat random-pattern skin flap: modulation by opioids
    S Kiumehr
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, P.O. Box 13145-784, Tehran, Iran
    Br J Plast Surg 58:58-64. 2005
    ..Furthermore naloxone significantly decreased the anti-ischaemic effect of the IPC. Systemic administrations of morphine had no significant effect on flap survival area in compare with the control group...
  11. ncbi Role of nitric oxide in hypodipsia of rats with obstructive cholestasis
    A R Mani
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Iran
    J Pharm Pharmacol 53:277-81. 2001
    ....
  12. ncbi NMDA receptor antagonists augment antidepressant-like effects of lithium in the mouse forced swimming test
    M Ghasemi
    Department of Pharmacology, School of Medicine, Medical Sciences, University of Tehran, Tehran, Iran
    J Psychopharmacol 24:585-94. 2010
    ..We for the first time suggested a role for NMDAR signalling in the antidepressant-like effects of lithium, providing a new approach for treatment of depression...
  13. ncbi Ultra-low dose naltrexone potentiates the anticonvulsant effect of low dose morphine on clonic seizures
    H Honar
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, PO Box 13145-784, Tehran, Iran
    Neuroscience 129:733-42. 2004
    ..The present data suggest that ultra-low doses of opioid receptor antagonists may provide a potent strategy to modulate seizure susceptibility, especially in conjunction with very low doses of opioids...
  14. ncbi Aminoguanidine improves epididymal sperm parameters in varicocelized rats
    M Abbasi
    Department of Anatomy, Tehran University of Medical Sciences, Poursina Street, Tehran, Iran
    Urol Int 86:302-6. 2011
    ..But there is no study to discriminate the subtype of catalytic enzyme for synthesis of NO. In this study, aminoguanidine (AG), an inducible NO synthase inhibitor, has been used to investigate its effect on sperm parameters...
  15. ncbi Methadone ameliorates multiple-low-dose streptozotocin-induced type 1 diabetes in mice
    K Amirshahrokhi
    Department of Pharmacology School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Toxicol Appl Pharmacol 232:119-24. 2008
    ..It seems that methadone as an opioid agonist may have a protective effect against destruction of beta cells and insulitis in the MLDS model of type 1 diabetes...
  16. ncbi Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats
    M Ghasemi
    Department of Pharmacology, School of Medicine, Medical Sciences University of Tehran, Tehran, Iran
    Br J Pharmacol 151:591-601. 2007
    ..The aim of the present study was to investigate the effect of biliary cirrhosis on NANC-mediated relaxation of rat corpus cavernosum and the possible roles of endocannabinoid and nitric oxide systems in this model...
  17. ncbi Possible evidence for involvement of new subtype of P1-purinoceptors in rat isolated uterus
    A R Dehpour
    Department of Pharmacology, Faculty of Medicine, Tehran University of Medical Sciences, Iran
    Gen Pharmacol 25:515-9. 1994
    ..5. The agonist potency order for the relaxation of contractions elicited by direct muscle stimulation was: CHA > L-PIA > 2-chloroadenosine > D-PIA > Ado. 6. The present data may propose the presence of a new subtype of P1-purinoceptor...
  18. ncbi High sensitivity of chicken's skeletal muscle sarcoplasmatic reticulum to effects of diltiazem or verapamil on calcium uptake and release
    N Mirazi
    Department of Biology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Pharmazie 61:625-30. 2006
    ..Chicken SR is about 1000 times more sensitive to the effects of diltiazem on Ca2+ uptake and release than rabbit SR as shown previously...
  19. ncbi The effect of chronic renal insufficiency on orthodontic tooth movement in rats
    M Shirazi
    Department of Orthodontics, School of Dentistry, Tehran University of Medical Sciences, Iran
    Angle Orthod 71:494-8. 2001
    ..The results suggest that an increase of bone-remodeling activities, as evident from a significantly higher level of PTH, may be responsible for increase in tooth movement...
  20. ncbi The effects of FK506 on the development and expression of morphine tolerance and dependence in mice
    H Homayoun
    Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Behav Pharmacol 14:121-7. 2003
    ..These data show the effectiveness of FK506 on morphine tolerance and dependence and suggest an additive effect between FK506 and the inhibition of constitutive NO synthesis in this regard...