Nima Rezaei

Summary

Affiliation: Asthma and Allergy Research Institute
Country: Iran

Publications

  1. ncbi request reprint Frequency and clinical manifestations of patients with primary immunodeficiency disorders in Iran: update from the Iranian Primary Immunodeficiency Registry
    Nima Rezaei
    Department of Allergy and Clinical Immunology of Children Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    J Clin Immunol 26:519-32. 2006
  2. ncbi request reprint Congenital neutropenia and primary immunodeficiency disorders: a survey of 26 Iranian patients
    Nima Rezaei
    From Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    J Pediatr Hematol Oncol 27:351-6. 2005
  3. ncbi request reprint Associated coronary anomalies in 135 Iranian patients with tetralogy of Fallot
    Manouchehr Hekmat
    Cardiac Surgery Ward, Modarres Hospital, Beheshti University of Medical Sciences, Saadat Abad, Tehran 19987, Iran
    Asian Cardiovasc Thorac Ann 13:307-10. 2005
  4. ncbi request reprint Laparoscopic cholecystectomy and open-heart surgery at the same time
    Manouchehr Hekmat
    Cardiac Surgery Ward of Modarres Hospital, Beheshti University of Medical Sciences, Tehran, Iran
    J Card Surg 20:557-9. 2005
  5. pmc Proinflammatory cytokine gene single nucleotide polymorphisms in common variable immunodeficiency
    N Rezaei
    Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    Clin Exp Immunol 155:21-7. 2009
  6. ncbi request reprint Therapeutic targeting of pattern-recognition receptors
    Nima Rezaei
    Division of Genomic Medicine, Royal Hallam shire Hospital, The University of Sheffield, Sheffield, UK
    Int Immunopharmacol 6:863-9. 2006
  7. ncbi request reprint Consanguinity in primary immunodeficiency disorders; the report from Iranian Primary Immunodeficiency Registry
    Nima Rezaei
    Department of Allergy and Clinical Immunology, Children Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Iran
    Am J Reprod Immunol 56:145-51. 2006
  8. ncbi request reprint The clinical and laboratory survey of Iranian patients with hyper-IgE syndrome
    Mostafa Moin
    Department of Allergy and Clinical Immunology of Children Medical Centre, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    Scand J Infect Dis 38:898-903. 2006
  9. ncbi request reprint The study of type 1 allergy prevalence among people of South-East of iran by skin prick test using common allergens
    H A Khazaei
    Department of Immunology and Internal Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
    Iran J Allergy Asthma Immunol 2:165-8. 2003
  10. ncbi request reprint Severe congenital neutropenia or hyper-IgM syndrome? A novel mutation of CD40 ligand in a patient with severe neutropenia
    Nima Rezaei
    Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Tehran, Iran
    Int Arch Allergy Immunol 147:255-9. 2008

Detail Information

Publications106 found, 100 shown here

  1. ncbi request reprint Frequency and clinical manifestations of patients with primary immunodeficiency disorders in Iran: update from the Iranian Primary Immunodeficiency Registry
    Nima Rezaei
    Department of Allergy and Clinical Immunology of Children Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    J Clin Immunol 26:519-32. 2006
    ..Construction of such registry is not only important for its epidemiological aspect but also for its role in increasing the physician's knowledge about such disorders...
  2. ncbi request reprint Congenital neutropenia and primary immunodeficiency disorders: a survey of 26 Iranian patients
    Nima Rezaei
    From Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    J Pediatr Hematol Oncol 27:351-6. 2005
    ..Although inherited neutropenias are rare, recurrent infections always deserves further evaluation for detecting such disorders...
  3. ncbi request reprint Associated coronary anomalies in 135 Iranian patients with tetralogy of Fallot
    Manouchehr Hekmat
    Cardiac Surgery Ward, Modarres Hospital, Beheshti University of Medical Sciences, Saadat Abad, Tehran 19987, Iran
    Asian Cardiovasc Thorac Ann 13:307-10. 2005
    ..Consideration of these anomalies during primary repair could decrease the risk of operation in such patients. However, it seems that the presence of anomalous coronary arteries does not affect incremental risk after surgical repair...
  4. ncbi request reprint Laparoscopic cholecystectomy and open-heart surgery at the same time
    Manouchehr Hekmat
    Cardiac Surgery Ward of Modarres Hospital, Beheshti University of Medical Sciences, Tehran, Iran
    J Card Surg 20:557-9. 2005
    ..Abdominal procedures in patients with coronary artery disease or severe valvular disease have high risk of mortality and morbidity...
  5. pmc Proinflammatory cytokine gene single nucleotide polymorphisms in common variable immunodeficiency
    N Rezaei
    Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    Clin Exp Immunol 155:21-7. 2009
    ..Cytokine single nucleotide polymorphisms could have a role in pathophysiology of CVID. High production of TNF-alpha is expected in some CVID patients based on the frequency of genotypes/haplotypes of these cytokine gene polymorphisms...
  6. ncbi request reprint Therapeutic targeting of pattern-recognition receptors
    Nima Rezaei
    Division of Genomic Medicine, Royal Hallam shire Hospital, The University of Sheffield, Sheffield, UK
    Int Immunopharmacol 6:863-9. 2006
    ..Further research on these receptors and their signalling pathways could help scientists to identify new candidates for therapeutic targeting...
  7. ncbi request reprint Consanguinity in primary immunodeficiency disorders; the report from Iranian Primary Immunodeficiency Registry
    Nima Rezaei
    Department of Allergy and Clinical Immunology, Children Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Iran
    Am J Reprod Immunol 56:145-51. 2006
    ..This study was accomplished in order to determine the frequency of consanguineous marriages in the families of patients with PiD...
  8. ncbi request reprint The clinical and laboratory survey of Iranian patients with hyper-IgE syndrome
    Mostafa Moin
    Department of Allergy and Clinical Immunology of Children Medical Centre, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    Scand J Infect Dis 38:898-903. 2006
    ..Although HIES is a rare condition, the recurrent infections should always raise a suspicion, which deserves further evaluation for detecting the syndrome...
  9. ncbi request reprint The study of type 1 allergy prevalence among people of South-East of iran by skin prick test using common allergens
    H A Khazaei
    Department of Immunology and Internal Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
    Iran J Allergy Asthma Immunol 2:165-8. 2003
    ..The prevalence of SPT-positive to common allergens is high among Iranian patients with allergic disorders. So, it should be recognized in the diagnosis of allergic diseases as well as in allergen-reduction programs...
  10. ncbi request reprint Severe congenital neutropenia or hyper-IgM syndrome? A novel mutation of CD40 ligand in a patient with severe neutropenia
    Nima Rezaei
    Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Tehran, Iran
    Int Arch Allergy Immunol 147:255-9. 2008
    ....
  11. doi request reprint Association of HAX1 deficiency with neurological disorder
    N Rezaei
    Immunology, Asthma and Allergy Research Institute, Medical Sciences, University of Tehran, Tehran, Iran
    Neuropediatrics 38:261-3. 2007
    ..She also suffered from psychomotor retardation and recurrent seizures. This case illustrates that HAX1 deficiency may be associated with a neurological phenotype...
  12. pmc Serum bactericidal antibody responses to meningococcal polysaccharide vaccination as a basis for clinical classification of common variable immunodeficiency
    Nima Rezaei
    Immunology, Asthma and Allergy Research Institute, Medical Sciences University of Tehran, Tehran 14194, Iran
    Clin Vaccine Immunol 15:607-11. 2008
    ..Vaccination response may define subgroups of patients with CVID, enabling more effective monitoring and therapeutic strategies...
  13. ncbi request reprint Increased serum levels of soluble CD30 in patients with common variable immunodeficiency and its clinical implications
    Nima Rezaei
    Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Medical Sciences University of Tehran, No 62, Dr Gharib st, Keshavarz Blvd, P O Box 14185 863 Tehran, 14194, Iran
    J Clin Immunol 28:78-84. 2008
    ..010). High levels of sCD30 in the CVID patients with splenomegaly and the presence of lymphoma in a patient with the highest level of sCD30 may suggest a soluble form of this marker as a prognostic tool in such diseases...
  14. ncbi request reprint The clinical, immunohematological, and molecular study of Iranian patients with severe congenital neutropenia
    Nima Rezaei
    Immunology, Asthma and Allergy Research Institute, Department of Allergy and Clinical Immunology of Children Medical Center, Medical Sciences University of Tehran, Tehran 14194, Iran
    J Clin Immunol 27:525-33. 2007
    ..Three patients died because of a severe infection. Although SCN is a rare disorder, early onset of severe and recurrent infections should always raise a suspicion, which deserves further evaluation for detecting such disorder...
  15. doi request reprint Association of IL-4 and IL-10 gene promoter polymorphisms with common variable immunodeficiency
    Nima Rezaei
    Immunology, Asthma and Allergy Research Institute, Children s Medical Center Hospital, Tehran University of Medical Sciences, Iran
    Immunobiology 215:81-7. 2010
    ..High production of IL-4 could also be expected based on haplotypes frequencies of this cytokine gene polymorphisms...
  16. ncbi request reprint Serum bactericidal antibody response to serogroup C polysaccharide meningococcal vaccination in children with primary antibody deficiencies
    Nima Rezaei
    Department of Allergy and Clinical Immunology of Children Medical Center, Immunology, Asthma and Allergy Research Institute, Medical Sciences University of Tehran, Tehran, Iran
    Vaccine 25:5308-14. 2007
    ..This supports the use of polysaccharide-containing vaccines in these patients...
  17. ncbi request reprint T- helper 1 and 2 cytokine assay in patients with common variable immunodeficiency
    N Rezaei
    Immunology, Asthma and Allergy Research Institute, Children s Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran
    J Investig Allergol Clin Immunol 18:449-53. 2008
    ..The pathogenesis of CVID is still unknown...
  18. doi request reprint Cytokine gene polymorphisms in common variable immunodeficiency
    Nima Rezaei
    Immunology, Asthma and Allergy Research Institute, Children s Medical Center Hospital, Tehran University of Medical Sciences 62 Qarib St, Keshavarz Blvd, PO Box 14185 863, Tehran 14194, Iran
    Int Arch Allergy Immunol 150:1-7. 2009
    ..Considering the significantly lower frequency of the high production haplotype (TG) and the higher frequency of the low production halplotype (TC) of TGF-beta, low production of this cytokine is expected in some CVID patients...
  19. ncbi request reprint The prevalence of penoscrotal abnormalities and inguinal hernia in elementary-school boys in the west of Iran
    Rooh Allah Yegane
    Department of Surgery, Logham Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Int J Urol 12:479-83. 2005
    ..We designed a cross-sectional study in order to determine the prevalence of inguinal hernia and penoscrotal abnormalities in the Lorestan province, situated in the west of Iran...
  20. ncbi request reprint T-helper 1, T-helper 2, and T-regulatory cytokines gene polymorphisms in irritable bowel syndrome
    Elham Barkhordari
    Molecular Immunology Research Center and Immunogenetic Laboratory, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Inflammation 33:281-6. 2010
    ..001). While production of cytokines could be affected by genetic polymorphisms within coding and promoter regions of cytokine genes, IL-4 and IL-10 gene polymorphisms could affect individual susceptibility to IBS...
  21. doi request reprint Cytokine single nucleotide polymorphisms in Iranian populations
    Ali Akbar Amirzargar
    Immunogenetic Laboratory, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Iran
    Eur Cytokine Netw 19:104-12. 2008
    ..Although some significant differences were observed for some cytokines, it seems that the cytokine gene polymorphism profile of the Iranian population is similar to that of Caucasians, particularly the Italian population...
  22. ncbi request reprint IL-10, TGF-beta, IL-2, IL-12, and IFN-gamma cytokine gene polymorphisms in asthma
    Masoud Movahedi
    Department of Allergy and Clinical Immunology of Children s Medical Center Hospital, Immunology, Asthma and Allergy Research Institute, Medical Sciences University of Tehran, Tehran, Iran
    J Asthma 45:790-4. 2008
    ..Considering the high frequency of presence of IL-10 ATA haplotype and the IL-2 GT genotype, it seems that the production of IL-10 and IL-2 in the asthmatic patients could be lower than normal subjects...
  23. doi request reprint Proinflammatory cytokine gene polymorphisms among Iranian patients with asthma
    Seyed Alireza Mahdaviani
    Department of Allergy and Clinical Immunology, Children s Medical Center Hospital, Immunology, Asthma, and Allergy Research Institute, Tehran University of Medical Sciences, 62 Gharib St, Keshavarz Blvd, P O Box 14185 863, Tehran, 14194, Iran
    J Clin Immunol 29:57-62. 2009
    ..Proinflammatory cytokines could contribute to this inflammatory process. This study was performed in order to analyze the genetic profile of proinflammatory cytokines in Iranian asthmatic patients...
  24. pmc Proinflammatory cytokine gene polymorphisms in irritable bowel syndrome
    Elham Barkhordari
    Department of Gastroenterology and Hepatology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
    J Clin Immunol 30:74-9. 2010
    ..Proinflammatory cytokines can play an important role in intestinal inflammation, while their production is under genetic control...
  25. ncbi request reprint Presence of Idiopathic Thrombocytopenic Purpura and autoimmune hemolytic anemia in the patients with common variable immunodeficiency
    Asghar Ramyar
    Department of Pediatrics, Division of Hematology, Children Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 7:169-75. 2008
    ..Chronic and recurrent ITP, especially in the presence of propensity to respiratory and gastrointestinal infections mandate the evaluation for an underlying immune dysregulation such as CVID...
  26. doi request reprint Neutropenia associated with X-linked Agammaglobulinemia in an Iranian referral center
    Asghar Aghamohammadi
    Department of Pediatrics, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 8:43-7. 2009
    ..Neutropenia in XLA is mainly associated with infection and is resolved with intravenous immunoglobulin replacement and antibiotics therapy...
  27. ncbi request reprint X-linked agammaglobulinemia: a survey of 33 Iranian patients
    Mostafa Moin
    Department of Allergy and Clinical Immunology of Children s Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    Immunol Invest 33:81-93. 2004
    ..9%, 75.8%, 33.3%, and 21.2% of XLA patients, respectively. The most common complications of these patients were chronic infections in 75.8% of them, including: chronic otitis media, chronic sinusitis, chronic diarrhea, and bronchiectasis...
  28. doi request reprint Analysis of switched memory B cells in patients with IgA deficiency
    Asghar Aghamohammadi
    Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Sciences, 62 Gharib Street, Tehran, Iran
    Int Arch Allergy Immunol 156:462-8. 2011
    ..Despite several investigations into the nature of the disease, the exact pathophysiology of SIGAD is still unknown...
  29. doi request reprint Immunologic evaluation of patients with recurrent ear, nose, and throat infections
    Asghar Aghamohammadi
    Department of Pediatrics, Children s Medical Center Hospital, Immunology, Asthma and Allergy Research Institute, Medical Sciences University of Tehran, Tehran, Iran
    Am J Otolaryngol 29:385-92. 2008
    ..In this study, we aimed to study the frequency of possible underlying immunodeficiency responsible for susceptibility to ear, nose, and throat (ENT) infection...
  30. doi request reprint IgA deficiency: correlation between clinical and immunological phenotypes
    Asghar Aghamohammadi
    Department of Pediatrics, Division of Immunology and Allergy, Children Medical Center Hospital, Tehran University of Medical Sciences, 62 Gharib St, Keshavarz Blvd, 14194, Tehran, Iran
    J Clin Immunol 29:130-6. 2009
    ..We aimed to investigate the clinical features in relation to immune function of Iranian patients with symptomatic IGAD...
  31. doi request reprint Comparison of pulmonary diseases in common variable immunodeficiency and X-linked agammaglobulinaemia
    Asghar Aghamohammadi
    Department of Pediatrics, Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Respirology 15:289-95. 2010
    ..Early diagnosis and appropriate treatment reduces the incidence of pulmonary infections in both groups of patients. However, CVID patients are prone to progressive lung disease despite optimal immunoglobulin therapy...
  32. ncbi request reprint Gastrointestinal manifestations in patients with common variable immunodeficiency
    Ahmad Khodadad
    Department of Pediatrics, Division of Gastroenterology, Children s Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Dig Dis Sci 52:2977-83. 2007
    ..CVID patients are at increased risk of infectious and inflammatory conditions in the GI tract. Early diagnosis of these complications improves the quality of life and well-being of patients...
  33. ncbi request reprint Ataxia-telangiectasia in Iran: clinical and laboratory features of 104 patients
    Mostafa Moin
    Department of Allergy and Clinical Immunology, Children s Medical Center, and Immunology, Asthma and Allergy Research Institute, Tehran, Iran
    Pediatr Neurol 37:21-8. 2007
    ..Average serum alpha-fetoprotein level was 149 +/- 137 ng/dL. The incidence of ataxia-telangiectasia in Iran is high, possibly due to familial marriages. Treatment should be focused on supportive management to prolong survival...
  34. ncbi request reprint Association of interleukin-2, interleukin-4 and transforming growth factor-beta gene polymorphisms with Behcet's disease
    Farhad Shahram
    Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Clin Exp Rheumatol 29:S28-31. 2011
    ..Cytokine single nucleotide polymorphisms could play a role in the pathophysiology of BD. The results of this study could suggest a tendency towards higher production of IL-2 and lower production of IL-4 in the patients with BD...
  35. pmc Serum bactericidal antibody response 1 year after meningococcal polysaccharide vaccination of patients with common variable immunodeficiency
    Nima Rezaei
    Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Clin Vaccine Immunol 17:524-8. 2010
    ....
  36. ncbi request reprint Autosomal recessive chronic granulomatous disease, IgA deficiency and refractory autoimmune thrombocytopenia responding to Anti-CD20 monoclonal antibody
    Bibi Shahin Shamsian
    Department of Pediatric Hematology Oncology, Immunology, Pathology, Mofid Children s Hospital, Tehran, Iran
    Iran J Allergy Asthma Immunol 7:181-4. 2008
    ..Patients with primary immunodeficiencies may have variable autoimmune manifestations. So for early detection and appropriate treatment, autoimmune diseases should always be suspected in such patients...
  37. doi request reprint B-cell-T-cell activation and interaction in common variable immunodeficiency
    Nima Rezaei
    Department of Infection and Immunity, The University of Sheffield, Sheffield, UK
    Hum Immunol 71:355-62. 2010
    ..In conclusion, this sample of CVID patients exhibits a defect of T-cell "help" to B cells, and/or B-cell response to T-cell help...
  38. ncbi request reprint Mannose-binding lectin polymorphisms in common variable immunodeficiency
    Asghar Aghamohammadi
    Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Clin Exp Med 9:285-90. 2009
    ..Mutant and low-producing MBL alleles and haplotypes might reflect as an associated genetic factor in CVID patients, which could play as a susceptibility factor in CVID...
  39. ncbi request reprint Clinical and laboratory findings in hyper-IgM syndrome with novel CD40L and AICDA mutations
    Asghar Aghamohammadi
    Center of Excellence for Pediatrics, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    J Clin Immunol 29:769-76. 2009
    ..These patients have immunoglobulin class switch recombination defects, caused by mutations in several genes...
  40. ncbi request reprint Primary immunodeficiency in Iran: first report of the National Registry of PID in Children and Adults
    Asghar Aghamohammadi
    Department of Clinical Pediatric Immunology, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    J Clin Immunol 22:375-80. 2002
    ..A comparative study shows some differences between our results and other registries...
  41. ncbi request reprint Effect of regular intravenous immunoglobulin therapy on prevention of pneumonia in patients with common variable immunodeficiency
    Zahra Pourpak
    Department of Allergy and Clinical Immunology, Children Medical Center, Tehran University of Medical Sciences, Tehran, IR Iran
    J Microbiol Immunol Infect 39:114-20. 2006
    ..The aim of this study was to evaluate the effectiveness of IVIG treatment in reducing the incidence of pneumonia in patients with CVID...
  42. pmc Clinical and immunological features of 65 Iranian patients with common variable immunodeficiency
    Asghar Aghamohammadi
    Department of Clinical Immunology of Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Clin Diagn Lab Immunol 12:825-32. 2005
    ..CVID should be considered in any patient with a history of recurrent infections and decreased levels of all serum immunoglobulin isotypes...
  43. ncbi request reprint Adverse reactions of prophylactic intravenous immunoglobulin infusions in Iranian patients with primary immunodeficiency
    Asghar Aghamohammadi
    Department of Allergy and Clinical Immunology of Children s Medical Center, Immunology Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    Ann Allergy Asthma Immunol 92:60-4. 2004
    ..Although long-term intravenous immunoglobulin infusion is an effective treatment for children with antibody deficiencies, it can be complicated by systemic adverse reactions...
  44. doi request reprint Health-related quality of life in primary antibody deficiency
    Asghar Aghamohammadi
    Research Center for Immunodeficiency, Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 10:47-51. 2011
    ..However, the patients with severe phenotypes and long delay in diagnosis showed lower QoL, even in medical management...
  45. ncbi request reprint Cutaneous granulomas in common variable immunodeficiency: case report and review of literature
    Asghar Aghamohammadi
    Department of Allergy and Clinical Immunology Children s Medical Center, No 62 Dr Gharib St, Keshavarz Blvd, Tehran, Iran
    Acta Dermatovenerol Croat 18:107-13. 2010
    ..In conclusion, taking history of recurrent infections and measuring immunoglobulin levels can be suggested in patients with granulomatous lesions instead of other expensive tests...
  46. ncbi request reprint Chronic granulomatous disease: a clinical survey of 41 patients from the Iranian primary immunodeficiency registry
    Masoud Movahedi
    Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Int Arch Allergy Immunol 134:253-9. 2004
    ..The present study was accomplished in order to determine the clinical spectrum of Iranian patients with CGD...
  47. ncbi request reprint IL-2, IFN-gamma, and IL-12 gene polymorphisms and susceptibility to multiple sclerosis
    Mohammad Ali Shokrgozar
    National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran
    J Clin Immunol 29:747-51. 2009
    ..In order to investigate the role of some proinflammatory cytokines (interleukin (IL)-2, IL-12, and interferon-gamma (IFN-gamma)) as a risk factor for MS, this study was performed...
  48. pmc Evaluation of antibody response to polysaccharide vaccine and switched memory B cells in pediatric patients with inflammatory bowel disease
    Gholamhossein Fallahi
    Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Gut Liver 8:24-8. 2014
    ..Inflammatory bowel disease (IBD) is a chronic disease of the gastrointestinal tract, whose etiologies are still unknown. This study was performed to evaluate the humoral immune response in terms of B cell functions in selected IBD patients...
  49. doi request reprint Association of human leukocyte antigen class I antigens in Iranian patients with pemphigus vulgaris
    Hossein Mortazavi
    Autoimmune Bullous Diseases Research Center, Department of Dermatology, Razi Hospital, Tehran, Iran
    J Dermatol 40:244-8. 2013
    ....
  50. doi request reprint The approach to children with recurrent infections
    Asghar Aghamohammadi
    Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 11:89-109. 2012
    ..If indicated, appropriate laboratory studies including simple screening and advanced tests must be performed...
  51. doi request reprint Study of programmed cell death 1 (PDCD1) gene polymorphims in Iranian patients with ankylosing spondylitis
    Narjes Soleimanifar
    Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Inflammation 34:707-12. 2011
    ..There was no evidence of association for PDCD1 SNPs with AS in our study, but CT genotype (PD-1.9) seems to be associated with HLA-B27 positivity in the patients with AS...
  52. doi request reprint BAK, BAX, and NBK/BIK proapoptotic gene alterations in Iranian patients with ataxia telangiectasia
    Anna Isaian
    National Institute of Genetic Engineering and Biotechnology, Tehran, Iran
    J Clin Immunol 30:132-7. 2010
    ..This study was designed to study the role of proapoptotic BAK, BAX, and NBK/BIK genes in a group of patients with AT to elucidate the possible role of these genes in progression of malignancies in this disease...
  53. ncbi request reprint Response to polysaccharide vaccination amongst pediatric patients with common variable immunodeficiency correlates with clinical disease
    Nima Rezaei
    Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 7:231-4. 2008
    ..In contrast, low populations of memory B-cells do not correlate with these sequelae. The results of this study could help pediatricians plan strategies for prevention of sequelae in children presenting with CVID...
  54. doi request reprint Progression of selective IgA deficiency to common variable immunodeficiency
    Asghar Aghamohammadi
    Department of Allergy and Clinical Immunology, Children s Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    Int Arch Allergy Immunol 147:87-92. 2008
    ..Early diagnosis of this conversion and institution of immunoglobulin therapy is effective in preventing severe bacterial infections and pulmonary insufficiency...
  55. doi request reprint HLA-B27 subtypes and tumor necrosis factor alpha promoter region polymorphism in Iranian patients with ankylosing spondylitis
    Mohammad Hossein Nicknam
    Molecular Immunology Research Center, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran, Rheumatology Research Centre, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Eur Cytokine Netw 20:17-20. 2009
    ..This study was performed to determine HLA-B27 subtypes among Iranian patients with AS, and to investigate TNF-alpha gene polymorphisms in the patient groups...
  56. doi request reprint Antibody response to pneumococcal capsular polysaccharide vaccination in patients with chronic kidney disease
    Majid Mahmoodi
    Cancer Research Center, Tehran University of Medical Sciences, Tehran, Iran
    Eur Cytokine Netw 20:69-74. 2009
    ..Nevertheless, this vaccination policy should be administered as it could prevent infection in responder patients...
  57. ncbi request reprint Severe combined immunodeficiency: a cohort of 40 patients
    Mehdi Yeganeh
    Immunology, Asthma and Allergy Research Institute, Division of Allergy and Clinical Immunology, Children s Medical Centre, Medical Sciences University of Tehran, Tehran, Iran
    Pediatr Allergy Immunol 19:303-6. 2008
    ..A complete blood count of cord blood could reveal lymphocytopenia at birth; this helps early diagnosis. Genetic consultation would help the families with affected members preventing new SCID offspring...
  58. doi request reprint Association of CTLA4 gene polymorphism in Iranian patients with ankylosing spondylitis
    Esfandiar Azizi
    Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Clin Immunol 30:268-71. 2010
    ..This study was performed to investigate the allele and genotype frequencies of CTLA4 gene polymorphisms in Iranian patients with ankylosing spondylitis (AS)...
  59. doi request reprint Behavior abnormality following intravenous immunoglobulin treatment in patients with primary antibody deficiencies
    Sepide Saroukhani
    Research Center for Immunodeficiencies, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Hum Psychopharmacol 25:419-22. 2010
    ..Meantime behavioral disorders reactions have not been reported yet. In this study, we describe for the first time a group of patients with PADs, who were under IVIG therapy and experienced some behavioral disorders...
  60. ncbi request reprint The clinical and laboratory manifestations of Iranian patients with cystic fibrosis
    Gholamhossein Fallahi
    Department of Pediatrics, Pediatrics Center of Excellence, Children s Medical Center, Tehran, Iran
    Turk J Pediatr 52:132-8. 2010
    ....
  61. ncbi request reprint Evaluation of liver diseases in Iranian patients with primary antibody deficiencies
    Farzaneh Motamed
    Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Ann Hepatol 8:196-202. 2009
    ..Patients with primary antibody deficiency (PAD) can complicate with liver disease. This study was performed in order to study the prevalence and causes of hepatobiliary diseases in Iranian patients with PAD...
  62. doi request reprint Co-administration of chenopodium album allergens and CpG oligodeoxynucleotides effects on peripheral blood mononuclear cells of patients with Allergic Rhinitis treated with intranasal corticosteroids and antihistamines
    Shokrollah Farrokhi
    Department of Immunology, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 10:101-10. 2011
    ..a or CpG/rCh.a that showed intracellular assay could be more sensitive than ELISA. Also, treatment with intranasal corticosteroids and antihistamines could enhance this CpG effect, in vitro...
  63. ncbi request reprint Efficacy of intravenous immunoglobulin on the prevention of pneumonia in patients with agammaglobulinemia
    Asghar Aghamohammadi
    Department of Allergy of Children s Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    FEMS Immunol Med Microbiol 40:113-8. 2004
    ..001). Treatment of agammaglobulinemia with IVIG significantly reduced the incidence of pneumonia and hospital admission. Intensive management and regular monitoring is required in order to fully prevent severe respiratory complications...
  64. ncbi request reprint Gastrointestinal manifestations of patients with chronic granulomatous disease
    Masoud Movahedi
    Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 3:83-7. 2004
    ..Also, failure to thrive was detected in 6 patients (10.5%). Four patients died (7%). CGD should be excluded in any patient with gastrointestinal manifestations especially chronic diarrhea, hepatic abscess, and gastric outlet obstruction...
  65. doi request reprint Impact of delayed diagnosis in children with primary antibody deficiencies
    Asghar Aghamohammadi
    Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    J Microbiol Immunol Infect 44:229-34. 2011
    ..To evaluate the diagnostic delay in Iranian PADs in association with their infections, we scored such manifestations to find an association between such delay and the scoring system...
  66. ncbi request reprint Screening of the Bruton Tyrosine Kinase (BTK) Gene Mutations in 13 Iranian Patients with Presumed X-Linked Agammaglobulinemia
    Asghar Aghamohammadi
    Department of Clinical Pediatric Immunology of Children s Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 3:175-9. 2004
    ..The results of this study further support the notion that molecular genetic testing represents an important tool for definitive and early diagnosis of XLA and may allow accurate carrier detection and prenatal diagnosis...
  67. doi request reprint Evaluation of immunoglobulin levels and infection rate in patients with common variable immunodeficiency after immunoglobulin replacement therapy
    Mahin Salehzadeh
    Department of Pediatrics, Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    J Microbiol Immunol Infect 43:11-7. 2010
    ..Common variable immunodeficiency (CVID) is characterized by decreased serum levels of IgG and increased susceptibility to recurrent infections. The aim of this study was to evaluate the IgG subclass levels of CVID patients...
  68. ncbi request reprint HLA class II (DRB, DQA1 and DQB1) allele and haplotype frequencies in the patients with pemphigus vulgaris
    Sheida Shams
    Department of Dermatology, Razi Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Clin Immunol 29:175-9. 2009
    ..Pemphigus vulgaris (PV), an autoimmune disease affecting the skin and mucous membranes, is associated with some human leukocyte antigen (HLA) class II alleles and haplotypes...
  69. ncbi request reprint Successful management of neutropenia in a patient with CD40 ligand deficiency by immunoglobulin replacement therapy
    Lida Atarod
    Department of Allergy and Clinical Immunology, Immunology, Asthma and Allergy Research Institute Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 6:37-40. 2007
    ..It seems that regular administration of sufficient doses of IVIG can be useful in the management of neutropenia in CD40 ligand deficiency, which results in better quality of life with decreasing occurrence of infection...
  70. ncbi request reprint Mortality in primary immunodeficient patients, registered in Iranian primary immunodeficiency registry
    Bahram Mir Saeid Ghazi
    Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 3:31-6. 2004
    ..6%) and salmonella in 1 (3.1%).Based on our study, delay in diagnosis in patients with PID results in tissue and organ damage and several complications. Mortality and morbidity are increased in undiagnosed patients...
  71. ncbi request reprint HAX1 mutation in an infant with severe congenital neutropenia
    Aziz Eghbali
    Department of Pediatric Hematology Oncology, Mofid Children s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    Turk J Pediatr 52:81-4. 2010
    ..Severe congenital neutropenia should be considered in children with early-onset recurrent infections and neutropenia, since early diagnosis and appropriate treatment can prevent further complications...
  72. ncbi request reprint Neutropenia and primary immunodeficiency diseases
    Nima Rezaei
    Center of Excellence for Pediatrics, Children s Medical Center, Tehran University of Medical Sciences, Tehran 14194, Iran rezaei
    Int Rev Immunol 28:335-66. 2009
    ..g., p14-deficiency, HAX1-deficiency, AK2-deficiency) has shed light on the pathophysiology of congenital neutropenia. This review summarizes the clinical, immunological, and genetic features of congenital neutropenia syndromes...
  73. ncbi request reprint Cytokine gene polymorphism in Iranian patients with chronic myelogenous leukaemia
    A A Amirzargar
    Immunogenetics Laboratory, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Int J Immunogenet 32:167-71. 2005
    ..The results suggest that production of TGF-beta in CML patients is higher and production of IL-4 and IL-10 is lower than in normal subjects...
  74. ncbi request reprint Polymorphisms in IL4 and iLARA confer susceptibility to asthma
    A A Amirzargar
    Immunogenetic Laboratory, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Investig Allergol Clin Immunol 19:433-8. 2009
    ..The production of interleukin (IL)-4, which can influence mast cell responsiveness to immunoglobulin (Ig) E--mediated signaling, could be modified by genetic variants in the IL-4 promoter...
  75. ncbi request reprint Cytokine single nucleotide polymorphisms in Iranian patients with pulmonary tuberculosis
    Ali Akbar Amirzargar
    Immunogenetic Laboratory, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    Eur Cytokine Netw 17:84-9. 2006
    ..Several genes coding for different cytokines may affect host susceptibility to tuberculosis...
  76. doi request reprint Echocardiographic abnormalities and their correlation with bronchiectasis score in primary antibody deficiencies
    Ali Akbar Zeinaloo
    Growth and Development Research Center, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    J Cardiovasc Med (Hagerstown) 11:244-9. 2010
    ..Our aim was to assess noninvasively the cardiac complications due to pulmonary disease in patients with primary antibody deficiency...
  77. ncbi request reprint Epidemiology of tuberculosis in the Southeastern Iran
    Hossein Ali Khazaei
    Zabol Medical Sciences College, Zahedan University of Medical Sciences, Zabol, Sistan and Baluchistan, Iran
    Eur J Epidemiol 20:879-83. 2005
    ..46. This region remains high TB rates. It is necessary to pay attention to the detection of TB, by making their register in order to enhance the effectiveness and to reduce the cost of existing methods...
  78. ncbi request reprint Necrosis of nasal cartilage due to mucormycosis in a patient with severe congenital neutropenia due to HAX1 deficiency
    A Fahimzad
    Pediatric Infections Research Center, Mofid Children Hospital, Shaheed Beheshti University of Sciences, Tehran, Iran
    J Investig Allergol Clin Immunol 18:469-72. 2008
    ..Recurrent and severe infections should alert physicians to possible immunodeficiency disease. Early diagnosis and appropriate treatment are the most important keys to preventing irreversible organ damage...
  79. ncbi request reprint Adverse reactions of prophylactic intravenous immunoglobulin; a 13-year experience with 3004 infusions in Iranian patients with primary immunodeficiency diseases
    S Dashti-Khavidaki
    Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
    J Investig Allergol Clin Immunol 19:139-45. 2009
    ..Adverse reactions to IVIG infusions are occasionally encountered; therefore, physicians and nurses should be aware of these reactions in order to manage and prevent them...
  80. ncbi request reprint ENT manifestations in Iranian patients with primary antibody deficiencies
    A Aghamohammadi
    Department of Allergy and Clinical Immunology, Children s Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    J Laryngol Otol 122:409-13. 2008
    ..One hundred and nine patients with primary antibody deficiencies were selected in order to determine the frequency of ENT complications...
  81. ncbi request reprint The association of HLA-DRB, DQA1, DQB1 alleles and haplotype frequency in Iranian patients with pulmonary tuberculosis
    A A Amirzargar
    Immunogenetic Laboratory, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran
    Int J Tuberc Lung Dis 8:1017-21. 2004
    ..To investigate HLA-DRB1, DQA1 and DQB1 allelic polymorphism in Iranian patients with pulmonary tuberculosis (PTB)...
  82. ncbi request reprint CD40 ligand expression on stimulated T-helper lymphocytes in patients with common variable immunodeficiency
    Masoud Ravanbakhsh
    Department of Immunology, School of Public Health and Institute of Public Health Research, Medical Sciences, University of Tehran, Tehran, Iran
    Iran J Allergy Asthma Immunol 6:129-35. 2007
    ..The results of this study are in agreement with some other studies, indicating that CD40 ligand expression on stimulated T-helper lymphocytes of Common variable immunodeficiency patients is similar to normal controls...
  83. ncbi request reprint Mortality and morbidity in common variable immunodeficiency
    Asghar Aghamohammadi
    Children s Medical Center, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
    J Trop Pediatr 53:32-8. 2007
    ..Based on our observation, it can be highlighted that all patients with CVID, even under regular immunoglobulin replacement, need close monitoring for early detection of complications and introduction of appropriate management...
  84. ncbi request reprint Lymphoma of mucosa-associated lymphoid tissue in common variable immunodeficiency
    Asghar Aghamohammadi
    Department of Clinical Pediatric Immunology, Children s Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Leuk Lymphoma 47:343-6. 2006
    ..Open lung biopsy showed a MALT lymphoma. Although a rare complication, pulmonary low grade B-cell lymphoma is a diagnosis that must be kept in mind in CVID patients with chronic pulmonary symptoms unresponsive to conventional therapies...
  85. ncbi request reprint Evaluation of humoral immune function in patients with bronchiectasis
    Parviz Tabatabaie
    Department of Infectious Diseases of Children s Medical Center Hospital, Medical Sciences University of Tehran, Tehran, Iran
    Iran J Allergy Asthma Immunol 7:69-77. 2008
    ..Early diagnosis and appropriate treatment will prevent the subsequent complications and improve quality of life of affected individuals...
  86. doi request reprint Cytokine response following transthoracic and transhiatal esophagectomy in patients with esophageal cancer
    Majid Mahmoodi
    Cancer Research Center, Medical Sciences University of Tehran, Tehran, Iran
    Eur Cytokine Netw 19:92-8. 2008
    ..Post-operatively, a significantly reduced production of Th1 and Th2 cytokines, except for IFN-gamma, was observed only in patients who had undergone surgical esophageal resection using the TT method...
  87. ncbi request reprint Effect of anti-epileptic drugs on serum immunoglobulin levels in children
    Mahmoudreza Ashrafi
    Department of Pediatrics, Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Acta Neurol Belg 110:65-70. 2010
    ..No patient at all showed significant decrease in serum IgM level. This study suggests that anti-epileptic drugs could reduce serum immunoglobulins, especially IgA and IgG; among them carbamazepine effect is of more concern...
  88. ncbi request reprint High production of IL-18 by dendritic cells induced by sera from patients with primary antibody deficiency
    Maryam Nourizadeh
    Immunology, Asthma and Allergy Research Institute, Medical Sciences Tehran University, Tehran, Iran
    Iran J Allergy Asthma Immunol 6:59-65. 2007
    ..55+/-0.68) ng/ml. These results suggest that the sera of patients with predominantly antibody deficiencies may contain soluble factor(s) that can induce a significant increase in IL-18 production by DCs...
  89. ncbi request reprint Study of alpha1-antitrypsin phenotypes frequencies in patients with primary antibody deficiency
    Mohammad Reza Fazlollahi
    Department of Allergy and Clinical Immunology, Children Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    Iran J Allergy Asthma Immunol 5:69-74. 2006
    ..Larger studies will be required to clarify the relationship between alpha-1-antitrypsin genotype and susceptibility to bronchiectasis in patients with antibody deficiency...
  90. ncbi request reprint Cytokine production by activated T cells in common variable immunodeficiency
    N Rezaei
    Research Group for Immunodeficiencies, Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    J Investig Allergol Clin Immunol 20:244-51. 2010
    ..Common variable immunodeficiency (CVID) is the most common symptomatic antibody deficiency. It is characterized by hypogammaglobulinemia, increased susceptibility to recurrent infections, autoimmunity, and malignancies...
  91. ncbi request reprint Distribution of primary immunodeficiency disorders diagnosed in the Children's Medical Center in Iran
    A Farhoudi
    Department of Allergy and Clinical Immunology, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    J Investig Allergol Clin Immunol 15:177-82. 2005
    ..A comparative study shows some differences between our results and other registries. This article also indicates that immunodeficiency disorders should be considered in patients with recurrent infections...
  92. ncbi request reprint Analysis of class-switched memory B cells in patients with common variable immunodeficiency and its clinical implications
    M Vodjgani
    Department of Immunology, School of Medicine, Medical Sciences University of Tehran, Tehran, Iran
    J Investig Allergol Clin Immunol 17:321-8. 2007
    ..It has been suggested that memory B cells, characterized by CD27 expression, can be used as a means to classify subsets of CVID patients...
  93. ncbi request reprint Severe congenital neutropenia in 2 siblings of consanguineous parents. The role of HAX1 deficiency
    S Mamishi
    Department of Pediatrics, Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
    J Investig Allergol Clin Immunol 19:500-3. 2009
    ..HAX1 deficiency should be considered in any child with severe infections and neutropenia, especially in children of consanguineous parents. Early diagnosis and appropriate treatment could prevent complications in this group of patients...
  94. ncbi request reprint Major histocompatibility complex class I and II antigens frequencies in Baloch ethnic group living in the southeast region of Iran
    H A Khazaei
    Department of Allergy and Clinical Immunology of Children s Medical Center Immunology, Asthma and Allergy Research Institute, Tehran, Iran
    Transplant Proc 36:1302-4. 2004
    ..Human leukocyte antigens have become key components to investigate the genetic relationships between populations...
  95. ncbi request reprint Pulmonary complications in primary hypogammaglobulinemia: a survey by high resolution CT scan
    M Gharagozlou
    Department of Allergy and Clinical Immunology, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
    Monaldi Arch Chest Dis 65:69-74. 2006
    ..Primary hypogammaglobulinemia disorders are a group of heterogeneous immunodeficiency syndromes with an increased susceptibility to pulmonary complications...
  96. ncbi request reprint Optic neuritis, multiple sclerosis and human leukocyte antigen: results of a 4-year follow-up study
    A A Amirzargar
    Immunogenetic Laboratory, Department of Immunology, Tehran University of Medical Sciences, Tehran, Iran
    Eur J Neurol 12:25-30. 2005
    ..In DQB1, the frequency of DQB1*0602 increased significantly in the MS patients. In conclusion existence of common genetic basis for early manifestations of MS could be suggested...
  97. doi request reprint Altered dendritic cell function in response to sera of common variable immunodeficiency patients
    M Nourizadeh
    Immunology, Asthma and Allergy Research Institute, Medical Sciences University of Tehran, Tehran, Iran
    Inflamm Res 56:527-32. 2007
    ..We evaluated the effects of CVID patient's sera as a source of microenvironmental factors on monocyte-derived DCs (MDCs)...
  98. ncbi request reprint HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease)
    Christoph Klein
    Department of Pediatric Hematology Oncology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Nat Genet 39:86-92. 2007
    ..Our findings suggest that HAX1 is a major regulator of myeloid homeostasis and underline the significance of genetic control of apoptosis in neutrophil development...
  99. ncbi request reprint Distribution of primary immunodeficiency diseases in the Turk ethnic group, living in the northwestern Iran
    Mahnaz Sadeghi Shabestari
    Division of Immunology Allergy, Tabriz Pediatrics Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
    J Clin Immunol 27:510-6. 2007
    ..The high incidence of severe combined immunodeficiency and ataxia-telangiectasia could be due to the genetic backgrounds in the Turk ethnic group...
  100. doi request reprint Novel HAX1 mutations in patients with severe congenital neutropenia reveal isoform-dependent genotype-phenotype associations
    Manuela Germeshausen
    Department of Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany
    Blood 111:4954-7. 2008
    ..Therefore, our findings suggest that HAX1 isoforms may play a distinctive role in the neuronal system...
  101. ncbi request reprint Neutropenia in Iranian patients with primary immunodeficiency disorders
    Nima Rezaei
    Haematologica 90:554-6. 2005
    ..The most common disorders were Shwachman-Diamond syndrome, cyclic neutropenia, Kostmann disease, Chediak-Higashi syndrome, hyper IgM syndromes, severe combined immunodeficiency, hyper IgE syndrome, and common variable immunodeficiency...