Research Topics
Genomes and GenesSpecies | Zahra PourpakSummaryAffiliation: Asthma and Allergy Research Institute Country: Iran Publications
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Publications
Behavioral characteristics in 3- to 12-month-old infant with atopic dermatitis: a case-control studyZahra Pourpak
Department of Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, IR Iran
Pediatr Allergy Immunol 18:339-45. 2007..Theoretically, higher scores in Perceptual Sensitivity, Soothability, and High Pleasure are concordant with the pervious studies about adrenomedullary system over activity...
Serum concentration of selenium in healthy individuals living in TehranR Safaralizadeh
Immunology, Asthma and Allergy Research Institute, Children Medical Center, Tehran University of Medical Sciences, PO Box 14185 938, Tehran, Iran
Nutr J 4:32. 2005..To investigate whether daily diet provides adequate selenium intake in healthy men and women living in Tehran, Iran...
Effect of regular intravenous immunoglobulin therapy on prevention of pneumonia in patients with common variable immunodeficiencyZahra Pourpak
Department of Allergy and Clinical Immunology, Children Medical Center, Tehran University of Medical Sciences, Tehran, IR Iran
J Microbiol Immunol Infect 39:114-20. 2006..The aim of this study was to evaluate the effectiveness of IVIG treatment in reducing the incidence of pneumonia in patients with CVID...
Which cereal is a suitable substitute for wheat in children with wheat allergy?Zahra Pourpak
Immunology, Asthma and Allergy Research Institute, Children Medical Center, Tehran University of Medical Sciences, Tehran, IR Iran
Pediatr Allergy Immunol 16:262-6. 2005..Considering concordance of positive SPT to wheat flour and wheat bran, avoiding both of them is necessary in patients with wheat allergy...
A study of malnutrition in Iranian patients with primary antibody deficiencyAzam Kouhkan
Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 3:189-96. 2004..It is recommeded that clinical immunologists and nutritionists should make a collective effort to provide these patients with standard or specialized diets so as to decrease the risk of infection...
Wheat anaphylaxis in childrenZahra Pourpak
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Children Medical Center, Tehran, Iran
Immunol Invest 36:175-82. 2007..prevention of first wheat-induced anaphylaxis episodes is almost impossible. It would, however, probably be good practice to educate physicians to recognize the common clinical manifestations of this disease for early management...
Wheat allergy: clinical and laboratory findingsZahra Pourpak
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Int Arch Allergy Immunol 133:168-73. 2004..Food allergy affects 6-8% of infants and wheat allergy is one of the common food allergies among children. The clinical and laboratory manifestations of wheat allergy were evaluated in this study...
Purified aged garlic extract modulates allergic airway inflammation in BALB/c miceAhad Zare
Department of Immunology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Iran J Allergy Asthma Immunol 7:133-41. 2008..Our findings in the present research suggested that aged garlic extract has the potential of attenuation of inflammatory features of allergic airway inflammation in murine model...
Serum bactericidal antibody responses to meningococcal polysaccharide vaccination as a basis for clinical classification of common variable immunodeficiencyNima Rezaei
Immunology, Asthma and Allergy Research Institute, Medical Sciences University of Tehran, Tehran 14194, Iran
Clin Vaccine Immunol 15:607-11. 2008..Vaccination response may define subgroups of patients with CVID, enabling more effective monitoring and therapeutic strategies...
IgA deficiency: correlation between clinical and immunological phenotypesAsghar Aghamohammadi
Department of Pediatrics, Division of Immunology and Allergy, Children Medical Center Hospital, Tehran University of Medical Sciences, 62 Gharib St, Keshavarz Blvd, 14194, Tehran, Iran
J Clin Immunol 29:130-6. 2009..We aimed to investigate the clinical features in relation to immune function of Iranian patients with symptomatic IGAD...
Cow's milk anaphylaxis in children first report of Iranian Food Allergy RegistryPegah Teymourpour
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 11:29-36. 2012..6%).It is concluded that cow's milk anaphylaxis may happen early in life. Regarding the severity of attacks and remarkable number of patients with several attacks, poor knowledge about this disorder is evident...
Inheritance pattern and clinical aspects of 93 Iranian patients with chronic granulomatous diseaseFatemeh Fattahi
Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Tehran University of Medical Sciences, No 62, Dr Gharib Street, Keshavarz Blvd, Tehran, 14194, IR, Iran
J Clin Immunol 31:792-801. 2011..Chronic granulomatous disease (CGD) is a rare immunodeficiency due to a genetic defect in one of the NADPH-oxidase components. We studied CGD inheritance forms (autosomal recessive (AR) or X-linked (XL)) and AR-CGD subtypes in Iran...
Frequency and clinical manifestations of patients with primary immunodeficiency disorders in Iran: update from the Iranian Primary Immunodeficiency RegistryNima Rezaei
Department of Allergy and Clinical Immunology of Children Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
J Clin Immunol 26:519-32. 2006..Construction of such registry is not only important for its epidemiological aspect but also for its role in increasing the physician's knowledge about such disorders...
Consanguinity in primary immunodeficiency disorders; the report from Iranian Primary Immunodeficiency RegistryNima Rezaei
Department of Allergy and Clinical Immunology, Children Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Iran
Am J Reprod Immunol 56:145-51. 2006..This study was accomplished in order to determine the frequency of consanguineous marriages in the families of patients with PiD...
The clinical, immunohematological, and molecular study of Iranian patients with severe congenital neutropeniaNima Rezaei
Immunology, Asthma and Allergy Research Institute, Department of Allergy and Clinical Immunology of Children Medical Center, Medical Sciences University of Tehran, Tehran 14194, Iran
J Clin Immunol 27:525-33. 2007..Three patients died because of a severe infection. Although SCN is a rare disorder, early onset of severe and recurrent infections should always raise a suspicion, which deserves further evaluation for detecting such disorder...
The clinical and laboratory survey of Iranian patients with hyper-IgE syndromeMostafa Moin
Department of Allergy and Clinical Immunology of Children Medical Centre, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Scand J Infect Dis 38:898-903. 2006..Although HIES is a rare condition, the recurrent infections should always raise a suspicion, which deserves further evaluation for detecting the syndrome...
Adverse reactions of prophylactic intravenous immunoglobulin infusions in Iranian patients with primary immunodeficiencyAsghar Aghamohammadi
Department of Allergy and Clinical Immunology of Children's Medical Center, Immunology Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Ann Allergy Asthma Immunol 92:60-4. 2004..However, to prevent occurrence of immediate adverse reactions during infusion in these patients, physicians should perform a detailed history and proper physical examination and check the titer of anti-IgA...
Detection of six novel mutations in WASP gene in fifteen Iranian Wiskott-Aldrich patientsSepideh Safaei
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 11:345-8. 2012..Mutation analysis for 15 boys with Wiskott-Aldrich syndrome was performed. Five previously reported mutations and six novel mutations including G8X, R41X, D283E, P412fsX446, E464X, and AfsX358 were detected...
Follow-up of the wheat allergy in children; consequences and outgrowing the allergyMahboubeh Mansouri
Department of Immunology and Allergy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 11:157-63. 2012..These patients were at risk for developing chronic allergic symptoms such as asthma. We also found that oral tolerance to wheat was happening in a minority of our patients...
Serum bactericidal antibody response 1 year after meningococcal polysaccharide vaccination of patients with common variable immunodeficiencyNima Rezaei
Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran
Clin Vaccine Immunol 17:524-8. 2010....
X-linked agammaglobulinemia: a survey of 33 Iranian patientsMostafa Moin
Department of Allergy and Clinical Immunology of Children s Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Immunol Invest 33:81-93. 2004..9%, 75.8%, 33.3%, and 21.2% of XLA patients, respectively. The most common complications of these patients were chronic infections in 75.8% of them, including: chronic otitis media, chronic sinusitis, chronic diarrhea, and bronchiectasis...
Chronic granulomatous disease: a clinical survey of 41 patients from the Iranian primary immunodeficiency registryMasoud Movahedi
Immunology, Asthma and Allergy Research Institute, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Int Arch Allergy Immunol 134:253-9. 2004..CONCLUSIONS: Early diagnosis of the disease is crucial. In view of the possibility of timely treatment, i.e. prophylactic treatment of infection, CGD should be excluded in any patient with unexplained infections or granulomas...
Clinical and immunological features of 65 Iranian patients with common variable immunodeficiencyAsghar Aghamohammadi
Department of Clinical Immunology of Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Clin Diagn Lab Immunol 12:825-32. 2005..CVID should be considered in any patient with a history of recurrent infections and decreased levels of all serum immunoglobulin isotypes...
Congenital neutropenia and primary immunodeficiency disorders: a survey of 26 Iranian patientsNima Rezaei
From Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
J Pediatr Hematol Oncol 27:351-6. 2005..Although inherited neutropenias are rare, recurrent infections always deserves further evaluation for detecting such disorders...
Quality of life in the Iranian adults with allergic rhinitisMansoureh Shariat
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 11:324-8. 2012..Therefore, nasal congestion was associated with sleep-disordered breathing, nocturnal sleep impairment, day time fatigue and somnolence which finally lead to QOL impairment...
Molecular analysis of four cases of chronic granulomatous disease caused by defects in NCF-2: the gene encoding the p67-phoxMohsen Badalzadeh
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 11:340-4. 2012..Although a gross deletion in other exons of NCF2 has been previously reported, a large deletion encompassing exon 2 has been not reported yet. This abstract was also presented in ESID 2012, Florence, Italy...
The cumulative activity of benzo(a)pyrene on systemic immune responses with mite allergen extract after intranasal instillation and ex vivo response to ovalbumin in miceKamran Kadkhoda
Department of Immunology, School of Medical Sciences, Tarbiat Modarres University, P O Box 14115 331, Tehran, Iran
Toxicol Lett 157:31-9. 2005..Thus, it may be another evidence on immunomodulatory effect of dendritic cells...
Autosomal recessive chronic granulomatous disease, IgA deficiency and refractory autoimmune thrombocytopenia responding to Anti-CD20 monoclonal antibodyBibi Shahin Shamsian
Department of Pediatric Hematology Oncology, Immunology, Pathology, Mofid Children s Hospital, Tehran, Iran
Iran J Allergy Asthma Immunol 7:181-4. 2008..Patients with primary immunodeficiencies may have variable autoimmune manifestations. So for early detection and appropriate treatment, autoimmune diseases should always be suspected in such patients...
Gastrointestinal manifestations of patients with chronic granulomatous diseaseMasoud Movahedi
Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 3:83-7. 2004..Also, failure to thrive was detected in 6 patients (10.5%). Four patients died (7%). CGD should be excluded in any patient with gastrointestinal manifestations especially chronic diarrhea, hepatic abscess, and gastric outlet obstruction...
Severe cutaneous reactions caused by barbiturates in seven Iranian childrenSetareh Mamishi
Department of Infectious Diseases, Immunology, Asthma and Allergy Research Institute, Children Medical Center, Medical Sciences University of Tehran, Tehran, Iran
Int J Dermatol 48:1254-61. 2009..In this article, we present seven children with severe adverse cutaneous reactions caused by barbiturates...
Evaluation of the effect of IL-22 on human cord blood CD4+ T cellsJavad Arasteh
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 9:59-67. 2010..Moreover, the results of suppression assay did not show any suppression effect on the cultured T cells. Thus, it seems that umbilical cord blood T cells probably do not express IL-22R1 on their surface...
Severe combined immunodeficiency: a cohort of 40 patientsMehdi Yeganeh
Immunology, Asthma and Allergy Research Institute, Division of Allergy and Clinical Immunology, Children s Medical Centre, Medical Sciences University of Tehran, Tehran, Iran
Pediatr Allergy Immunol 19:303-6. 2008..A complete blood count of cord blood could reveal lymphocytopenia at birth; this helps early diagnosis. Genetic consultation would help the families with affected members preventing new SCID offspring...
Synbiotics could not reduce the scoring of childhood atopic dermatitis (SCORAD): a randomized double blind placebo-controlled trialAlireza Shafiei
Department of Allergy and Immunology, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 10:21-8. 2011..This study could not confirm synbiotic as an effective treatment for childhood atopic dermatitis and further studies are needed. These findings challenge the role of synbiotics in the treatment of childhood atopic dermatitis...
Prevention and control of infections in patients with severe congenital neutropenia; a follow up studyTahmineh Salehi
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 11:51-6. 2012..Treatment with GCSF significantly reduced the duration and the frequency of hospitalization. Because of plausible progression to AML/MDS, regular follow-up of patients should be continued...
Efficacy of intravenous immunoglobulin on the prevention of pneumonia in patients with agammaglobulinemiaAsghar Aghamohammadi
Department of Allergy of Children's Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
FEMS Immunol Med Microbiol 40:113-8. 2004..001). Treatment of agammaglobulinemia with IVIG significantly reduced the incidence of pneumonia and hospital admission. Intensive management and regular monitoring is required in order to fully prevent severe respiratory complications...
Screening of the Bruton Tyrosine Kinase (BTK) Gene Mutations in 13 Iranian Patients with Presumed X-Linked AgammaglobulinemiaAsghar Aghamohammadi
Department of Clinical Pediatric Immunology of Children s Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 3:175-9. 2004..The results of this study further support the notion that molecular genetic testing represents an important tool for definitive and early diagnosis of XLA and may allow accurate carrier detection and prenatal diagnosis...
Increased serum levels of soluble CD30 in patients with common variable immunodeficiency and its clinical implicationsNima Rezaei
Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Medical Sciences University of Tehran, No 62, Dr Gharib st, Keshavarz Blvd, P O Box 14185 863 Tehran, 14194, Iran
J Clin Immunol 28:78-84. 2008..010). High levels of sCD30 in the CVID patients with splenomegaly and the presence of lymphoma in a patient with the highest level of sCD30 may suggest a soluble form of this marker as a prognostic tool in such diseases...
Adverse drug reactions in patients in an Iranian department of internal medicineSara Pourseyed
Immunology, Asthma and Allergy Research Institute, Children Medical Center, Medical Sciences University of Tehran, Tehran, IR Iran
Pharmacoepidemiol Drug Saf 18:104-10. 2009..The department of internal medicine is not an exception to this issue. This study was performed to determine the nature and frequency of ADRs in an internal medicine ward in Iran...
Behavioral characteristics in 18- to 36-month-old toddlers with atopic dermatitis compared with healthy childrenLeyla Sedighipour
Immunology, Asthma and Allergy Research Institute, Medical Sciences University of Tehran, Tehran, Iran
Pediatr Dermatol 27:314-5. 2010..They tended to be more energetic and impulsive, and also showed more excitement when subjected to novel stimuli...
Different pattern of gene mutations in Iranian patients with severe congenital neutropenia (including 2 new mutations)Zahra Alizadeh
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 12:86-92. 2013....
Assessment of sensitization to insect aeroallergens among patients with allergic rhinitis in Yazd City, IranMohammad Hassan Bemanian
Immunology, Asthma and Allergy Research Institute, Children Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 11:253-8. 2012..Our study could highlight the importance of insect aeroallergens for clinicians for better diagnosis and management of patients with allergic rhinitis...
Selective immunoglobulin A deficiency in Iranian blood donors: prevalence, laboratory and clinical findingsShiva Saghafi
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 7:157-62. 2008..Our study suggests that; due to high frequency of IgA deficiency in Iran, it seems necessary to measure IgA levels for every blood donor and blood recipient to find IgA deficient cases...
Serum selenium concentration in healthy children living in TehranReza Safaralizadeh
Immunology, Asthma and Allergy Research Institute, Medical Sciences University of Tehran, Tehran, I R Iran
Biofactors 31:127-31. 2007..Reliable age-specific reference values for selenium in children in Iran are not clear and are important for the identification of selenium deficiency and some other researches that is the aim of this study...
Clinical and laboratory findings in Iranian patients with leukocyte adhesion deficiency (study of 15 cases)Masoud Movahedi
Immunology, Asthma and Allergy Research Institute, Children Medical Center, Tehran University of Medical Sciences, IR, Iran
J Clin Immunol 27:302-7. 2007..Furthermore, because of considerable rate of consanguineous marriages in parents of LAD patients, we suggested more genetic studies on this disease and genetic consultation for these families...
Mortality and morbidity in common variable immunodeficiencyAsghar Aghamohammadi
Children s Medical Center, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
J Trop Pediatr 53:32-8. 2007..Based on our observation, it can be highlighted that all patients with CVID, even under regular immunoglobulin replacement, need close monitoring for early detection of complications and introduction of appropriate management...
Mortality in primary immunodeficient patients, registered in Iranian primary immunodeficiency registryBahram Mir Saeid Ghazi
Immunology, Asthma and Allergy Research Institute, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 3:31-6. 2004..6%) and salmonella in 1 (3.1%).Based on our study, delay in diagnosis in patients with PID results in tissue and organ damage and several complications. Mortality and morbidity are increased in undiagnosed patients...
Primary hemophagocytic lymphohistiocytosis in Iran: report from a single referral centerBibi Shahin Shamsian
Department of Pediatric Hematology Oncology, Mofid Children s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Pediatr Hematol Oncol 29:215-9. 2012..Herein the authors report 6 Iranian patients with primary HLH and their outcome from a single tertiary-care center...
Health-related quality of life in primary immune deficient patientsHabibeh Mozaffari
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 5:23-7. 2006..PI patients may need psychological consultation for better coping with their illness...
Quality of life in atopic dermatitis patientsHabibeh Mozaffari
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, IR, Iran
J Microbiol Immunol Infect 40:260-4. 2007..Atopic dermatitis (AD) is a common skin condition. The aim of this study was to evaluate the impact of AD on the quality of life of children or adults and to identify the area of patients' lives most affected by the disease...
Adverse reactions to antibiotics in hospitalized Iranian childrenGhamar Taj Khotaei
Department of Infectious Diseases, Children s Medical Center, Medical Sciences University of Tehran, Tehran, Iran
J Microbiol Immunol Infect 41:160-4. 2008..The aim of this study was to determine the frequency of adverse reactions to antibiotics by organ system in hospitalized children in the infectious ward of a pediatric diseases referral center in Iran...
Cytokine gene polymorphism and asthma susceptibility, progress and control levelSaeed Daneshmandi
Department of Immunology, Tarbiat Modares University, Faculty of Medical Sciences, Tehran, Iran
Mol Biol Rep 39:1845-53. 2012..To achieve an appropriate schema for asthma management, further studies with consideration of different aspects in a larger group of patients would be more elucidative...
Two cases of syndromic neutropenia with a report of novel mutation in G6PC3Zahra Alizadeh
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 10:227-30. 2011..It can be concluded that G6PC3 is one of the responsible gene for SCN in Iranian patients. Based on the results, a new mutation in G6PC3 observed in one patient...
Adenosine deaminase in patients with primary immunodeficiency syndromes: the analysis of serum ADA1 and ADA2 activitiesPegah Poursharifi
Department of Biology, Faculty of Basic Sciences, Payame Noor University, Tehran, Iran
Clin Biochem 42:1438-43. 2009..We aimed to investigate the activity of ADA and its isoenzymes in serum of patients with various primary immunodeficiency (PID) syndromes...
Clinical, immunological and molecular characteristics of 37 Iranian patients with X-linked agammaglobulinemiaAsghar Aghamohammadi
Division of Clinical Pediatric Immunology, Children s Medical Center, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Int Arch Allergy Immunol 141:408-14. 2006..Eighty-five percent of the patients with this phenotype have mutations in Bruton's tyrosine kinase (BTK) gene...
Identification of an SH2D1A mutation in a hypogammaglobulinemic male patient with a diagnosis of common variable immunodeficiencyAsghar Aghamohammadi
Department of Clinical Pediatric Immunology, Children's Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran
Int J Hematol 78:45-7. 2003..The results support the notion that the possibility of a SH2D1A gene mutation should be considered in hypogammaglobulinemic male patients before a diagnosis of CVID is made...
Asthma knowledge, attitude, and self-efficacy in Iranian asthmatic patientsLaleh Sharifi
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Arch Iran Med 14:315-20. 2011..Therefore, this study examined the relationship between knowledge, attitudes, and self-efficacy with socio-economic factors in Iranian asthmatic patients during 2006-2008...
Low magnesium concentration in erythrocytes of children with acute asthmaMostafa Sedighi
Immunology, Asthma and Allergy Research Institute, Children Medical Center, No. 62, Dr. Gharib St, Keshavarz Blvd, Tehran 14194, Iran
Iran J Allergy Asthma Immunol 5:183-6. 2006..There are recommendations for using intravenous Mg sulfate in acute asthma, and this study supports the rational for using it in emergency departments for acute severe asthma...
FcepsilonRI-alpha siRNA inhibits the antigen-induced activation of mast cellsReza Safaralizadeh
Department of Biochemistry, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran
Iran J Allergy Asthma Immunol 8:177-83. 2009..In conclusion, knock-down of FcepsilonRI-alpha by siRNA could be a promising method for inhibition of the mast cell-mediated allergic reactions...
Prevalence of IgA deficiency in children with juvenile rheumatoid arthritisMohammad Hasan Moradinejad
Department of Rheumatology, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 10:35-40. 2011..Hence, future epidemiological studies are warranted to make it clear...
A latex-induced allergic airway inflammation model in miceParvaneh Farzaneh
Immunology Department, School of Medical Sciences, Tarbiat Modarres University, Tehran, Iran
Basic Clin Pharmacol Toxicol 99:405-11. 2006..These studies demonstrate that sensitization and subsequent aerosol inhalational challenge of latex allergen extract promotes allergic airway inflammation characterized by elevated IL-5 and IL-13 and eosinophils...
The study of egg allergy in children with atopic dermatitisTahmineh Salehi
From the 1Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran 2Department of Immunology, Children s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
World Allergy Organ J 2:123-7. 2009..Food allergy plays a significant pathogenic role among children with atopic dermatitis (AD)...
Normal range determination of lymphocytes subsets in normal adults in IranRaheleh Shokouhi Shoormasti
Children Medical Center, Tehran, Iran
Iran J Allergy Asthma Immunol 10:295-8. 2011....
Understanding adverse drug reactions and drug allergies: principles, diagnosis and treatment aspectsZahra Pourpak
Immunology, Asthma and Allergy Research Institute, Medical Sciences University of Tehran, Tehran, IR, Iran
Recent Pat Inflamm Allergy Drug Discov 2:24-46. 2008..Priorities in the evaluation and management of the conditions of patients who have experienced allergic and non-allergic drug reactions also will be discussed...
Serum bactericidal antibody response to serogroup C polysaccharide meningococcal vaccination in children with primary antibody deficienciesNima Rezaei
Department of Allergy and Clinical Immunology of Children Medical Center, Immunology, Asthma and Allergy Research Institute, Medical Sciences University of Tehran, Tehran, Iran
Vaccine 25:5308-14. 2007..This supports the use of polysaccharide-containing vaccines in these patients...
Adverse drug reactions in hospitalized children in a department of infectious diseasesFatemeh Fattahi
Immunology, Asthma and Allergy Research Institute, Children Medical Center, Tehran University of Medical Sciences, Tehran 14194, Iran
J Clin Pharmacol 45:1313-8. 2005
Frequency of asthma as the cause of dyspnea in pregnancyKatayoon Bidad
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran
Int J Gynaecol Obstet 111:140-3. 2010..To estimate the prevalence of asthma among pregnant women with dyspnea...
Primary immunodeficiency in Iran: first report of the National Registry of PID in Children and AdultsAsghar Aghamohammadi
Department of Clinical Pediatric Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
J Clin Immunol 22:375-80. 2002..A comparative study shows some differences between our results and other registries...
Anterior chest wall protrusion as initial presentation of chronic granulomatous disease: a case reportSetareh Mamishi
Department of Pediatric Infectious Disease, Children Medical Center, Tehran University of Medical Sciences, Tehran, I R Iran
Pediatr Allergy Immunol 16:685-7. 2005..We report a 4-month-old girl with CGD, was firstly presented with an anterior chest wall protrusion because of an aspergillosis mass...
Osteomyelitis as a late complication of Bacille Calmette-Guérin vaccinationGhamar Taj Khotaei
Department of Infectious Disease, Children Medical Center, Tehran University of Medical Sciences, Tehran, IR Iran
J Microbiol Immunol Infect 39:169-72. 2006..He had no evidence of immunodeficiency. After antituberculous therapy and surgical treatment, the bone lesions disappeared and he was discharged from hospital without any sequela during 11 months of follow-up...
Comparative study of the pollen protein contents in two major varieties of Cupressus arizonica planted in TehranYoucef Shahali
Immunology, Asthma and Allergy Research Institute, Medical Sciences, University of Tehran, Iran
Iran J Allergy Asthma Immunol 6:123-7. 2007..The confirmation of these aspects would facilitate the preparation of an effective extract, improving the diagnosis of the allergy to the Cupressus arizonica pollen...
Cutaneous manifestations of primary immunodeficiency diseases in childrenAthar Moin
Department of Dermatology, Faculty of Medicine, Shahed University, Tehran, Iran
Iran J Allergy Asthma Immunol 5:121-6. 2006..Our findings support the results of other studies that most PIDs have cutaneous features which being their typical aspects are highly suggestive for the diagnosis of PIDs...
Selenium and intractable epilepsy: is there any correlation?Mahmood Reza Ashrafi
Tehran University of Medical Sciences, Children s Medical Center, Tehran, Iran
Pediatr Neurol 36:25-9. 2007..Measurement of serum selenium in patients with intractable epilepsy should be considered...
Purification and refolding of Escherichia coli-expressed recombinant human interleukin-2Samaneh Esfandiar
Biotechnology Group, Chemical Engineering Department, Tarbiat Modares University, P O Box 14115 143, Tehran, Iran
Biotechnol Appl Biochem 55:209-14. 2010..Using this method, rhIL-2 was collected at 97% purity and its activity was measured by the lymphocyte transformation test. The measured activity was identical with commercial human interleukin-2...
The effect of IL-28A on human cord blood CD4+ T cellsJavad Arasteh
Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
Immunopharmacol Immunotoxicol 32:339-47. 2010..The aim of this study was to identify biological activity of IL-28 on cord blood CD4(+) T cells...
Determination of HLA-B27 subtypes in Iranian patients with ankylosing spondylitisMohamad Hossein Nicknam
Molecular Immunology Research Center, Faculty of Medicine, Medical Sciences University of Tehran, Tehran, Iran
Iran J Allergy Asthma Immunol 7:19-24. 2008..6%). Our results showed a restricted number of HLA-B27 subtypes associated with AS in Iran and an elevated frequency of the B*2705 allele in these patients similar to other Euro-Caucasoid (Aryan) groups in the world...
Prevalence of asthma related to BMI in adolescents in Tehran, Iran, 2004-2005Katayoon Bidad
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, No 62, Dr Gharib st, Keshavarz Blvd, Tehran, 14194, Iran
Eur J Pediatr 166:453-4. 2007..Both asthma and obesity have become more common in affluent societies during the recent decades, and several studies have shown a correlation between the presence of asthma and obesity...
CYBB Gene Mutation Detection in an Iranian Patient with Chronic Granulomatous DiseaseZahra Rezvani
Immunology, Asthma and Allergy Research Institute, Children Medical Center, Tehran University of Medical Sciences, Tehran, Iran
Iran J Allergy Asthma Immunol 4:103-6. 2005..We also observed a change (-270 CA) in the promoter region which needs further investigation.We would like to pursue this study by analyzing more X-CGD patients to find out the CYBB mutation spectrum in Iranian patients...
The ex vivo study of synergistic effects of polycyclic aromatic hydrocarbon, benzo(a)pyrene with ovalbumin on systemic immune responses by oral routeKamran Kadkhoda
Department of Immunology, School of Medical Sciences, Tarbiat Modarres University, P O Box 14115 331, Tehran, Iran
Toxicology 199:261-5. 2004..These results suggest that BP may act as a mucosal adjuvant in the gut enhancing systemic Th1 and Th2 immune responses and might play a role in oral immunization and food allergy...
Systemic and local reactions of bee venom immunotherapy in IranMohammad Hassan Bemanian
Department of Pediatrics, Shahid Sadoughi Hospital, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Iran J Allergy Asthma Immunol 6:203-6. 2007..No patient experienced severe systemic reaction. Cluster protocol for hymenoptera immunotherapy is a reliable method for the treatment of anaphylactic reactions to bee venom. It is safe with low cost and do not need hospitalization...
Neutropenia in Iranian patients with primary immunodeficiency disordersNima Rezaei
Haematologica 90:554-6. 2005..The most common disorders were Shwachman-Diamond syndrome, cyclic neutropenia, Kostmann disease, Chediak-Higashi syndrome, hyper IgM syndromes, severe combined immunodeficiency, hyper IgE syndrome, and common variable immunodeficiency...
Prevalence of type I allergy to natural rubber latex and type IV allergy to latex and rubber additives in operating room staff with glove-related symptomsSara Miri
Department of Laboratory Medicine, Harborview Medical Center, University of Washington, Seattle, WA 98104, USA
Allergy Asthma Proc 28:557-63. 2007..Based on this study, we recommend eliminating powdered latex gloves from the operating rooms of the 13 studied general hospitals and support the substitution of powder-free latex gloves...
Adverse drug reactions in a department of pediatric surgeryShockrollah Farrokhi
J Trop Pediatr 52:72-3. 2006
DNA banking of primary immunodeficiency disorders in iranAnna Isaian
Iran J Allergy Asthma Immunol 5:201-2. 2006..DNA banking is a useful method for further detection of mutation in immunodeficient patients and prenatal diagnosis for presence or absence of the disorder in the fetus which can be confirmed by molecular genetics testing...
Toxic epidermal necrolysis associated with concomitant use of lamotrigine and carbamazepine: a case reportParvin Mansouri
Arch Dermatol 141:788-9. 2005
