Leon R Ochiai

Summary

Affiliation: International Vaccine Institute

Publications

  1. pmc Vivax malaria and bacteraemia: a prospective study in Kolkata, India
    Sujit Kumar Bhattacharya
    Society for Applied Studies, Kolkata, India
    Malar J 12:176. 2013
  2. pmc Replacing paper data collection forms with electronic data entry in the field: findings from a study of community-acquired bloodstream infections in Pemba, Zanzibar
    Kamala Thriemer
    International Vaccine Institute, SNU Research Park, San 4 8, Nakseongdae dong, Gwanak Gu, Seoul, Republic of Korea 151 600
    BMC Res Notes 5:113. 2012
  3. pmc Schools as potential vaccination venue for vaccines outside regular EPI schedule: results from a school census in Pakistan
    Sajid Bashir Soofi
    Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan
    BMC Res Notes 5:6. 2012
  4. pmc Decreasing incidence of severe malaria and community-acquired bacteraemia among hospitalized children in Muheza, north-eastern Tanzania, 2006-2010
    George Mtove
    National Institute for Medical Research Amani Centre, Tanga, Tanzania
    Malar J 10:320. 2011
  5. pmc Spatial risk for gender-specific adult mortality in an area of southern China
    Mohammad Ali
    International Vaccine Institute, Seoul, Korea
    Int J Health Geogr 6:31. 2007
  6. pmc A mass vaccination campaign targeting adults and children to prevent typhoid fever in Hechi; expanding the use of Vi polysaccharide vaccine in southeast China: a cluster-randomized trial
    Jin Yang
    Division of Bacterial Diseases, Guangxi Center for Disease Control, 80 Taoyuan Road, Nanning 530021, Guangxi, China
    BMC Public Health 5:49. 2005
  7. pmc Salmonella paratyphi A rates, Asia
    R Leon Ochiai
    International Vaccine Institute, Kwanak PO Box 14, Seoul, South Korea 151 600
    Emerg Infect Dis 11:1764-6. 2005
  8. pmc A study of typhoid fever in five Asian countries: disease burden and implications for controls
    R Leon Ochiai
    International Vaccine Institute, Seoul, Republic of Korea
    Bull World Health Organ 86:260-8. 2008
  9. ncbi The use of typhoid vaccines in Asia: the DOMI experience
    R Leon Ochiai
    International Vaccine Institute, Kwanak gu, Seoul, Korea
    Clin Infect Dis 45:S34-8. 2007
  10. ncbi A multi-country cluster randomized controlled effectiveness evaluation to accelerate the introduction of Vi polysaccharide typhoid vaccine in developing countries in Asia: rationale and design
    Camilo J Acosta
    International Vaccine Institute, Seoul, South Korea
    Trop Med Int Health 10:1219-28. 2005

Collaborators

Detail Information

Publications25

  1. pmc Vivax malaria and bacteraemia: a prospective study in Kolkata, India
    Sujit Kumar Bhattacharya
    Society for Applied Studies, Kolkata, India
    Malar J 12:176. 2013
    ..Data from a prospective fever surveillance study in Kolkata, India were reanalysed for the potential association between Plasmodium vivax malaria and bacteraemia...
  2. pmc Replacing paper data collection forms with electronic data entry in the field: findings from a study of community-acquired bloodstream infections in Pemba, Zanzibar
    Kamala Thriemer
    International Vaccine Institute, SNU Research Park, San 4 8, Nakseongdae dong, Gwanak Gu, Seoul, Republic of Korea 151 600
    BMC Res Notes 5:113. 2012
    ..It is gaining in popularity and has replaced the paper-based data entry system in many studies. We report our experiences with paper- and PDA-based data collection during a fever surveillance study in Pemba Island, Zanzibar, Tanzania...
  3. pmc Schools as potential vaccination venue for vaccines outside regular EPI schedule: results from a school census in Pakistan
    Sajid Bashir Soofi
    Department of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan
    BMC Res Notes 5:6. 2012
    ..abstract:..
  4. pmc Decreasing incidence of severe malaria and community-acquired bacteraemia among hospitalized children in Muheza, north-eastern Tanzania, 2006-2010
    George Mtove
    National Institute for Medical Research Amani Centre, Tanga, Tanzania
    Malar J 10:320. 2011
    ..The annual incidence and temporal trend of severe malaria and community-acquired bacteraemia during a four-year period in Muheza, Tanzania was assessed...
  5. pmc Spatial risk for gender-specific adult mortality in an area of southern China
    Mohammad Ali
    International Vaccine Institute, Seoul, Korea
    Int J Health Geogr 6:31. 2007
    ..We constructed spatially smoothed risk maps for gender-specific adult mortality in an area of southern China comprising both urban and rural areas and identified ecological factors of gender-specific mortality across societies...
  6. pmc A mass vaccination campaign targeting adults and children to prevent typhoid fever in Hechi; expanding the use of Vi polysaccharide vaccine in southeast China: a cluster-randomized trial
    Jin Yang
    Division of Bacterial Diseases, Guangxi Center for Disease Control, 80 Taoyuan Road, Nanning 530021, Guangxi, China
    BMC Public Health 5:49. 2005
    ....
  7. pmc Salmonella paratyphi A rates, Asia
    R Leon Ochiai
    International Vaccine Institute, Kwanak PO Box 14, Seoul, South Korea 151 600
    Emerg Infect Dis 11:1764-6. 2005
    ..Paratyphi A. We compared their incidences by using standardized methods from population-based studies in China, Indonesia, India, and Pakistan...
  8. pmc A study of typhoid fever in five Asian countries: disease burden and implications for controls
    R Leon Ochiai
    International Vaccine Institute, Seoul, Republic of Korea
    Bull World Health Organ 86:260-8. 2008
    ..To inform policy-makers about introduction of preventive interventions against typhoid, including vaccination...
  9. ncbi The use of typhoid vaccines in Asia: the DOMI experience
    R Leon Ochiai
    International Vaccine Institute, Kwanak gu, Seoul, Korea
    Clin Infect Dis 45:S34-8. 2007
    ..The Diseases of the Most Impoverished (DOMI) Program was initiated to provide evidence to decide on the introduction of typhoid vaccines in Asian countries...
  10. ncbi A multi-country cluster randomized controlled effectiveness evaluation to accelerate the introduction of Vi polysaccharide typhoid vaccine in developing countries in Asia: rationale and design
    Camilo J Acosta
    International Vaccine Institute, Seoul, South Korea
    Trop Med Int Health 10:1219-28. 2005
    ..Preliminary results are presented that determined the final planning of the trial before immunization. Important methodological and practical issues regarding vaccine cluster randomized designs are illustrated...
  11. ncbi The role of epidemiology in the introduction of vi polysaccharide typhoid fever vaccines in Asia
    Camilo J Acosta
    International Vaccine Institute, Seoul, Republic of Korea
    J Health Popul Nutr 22:240-5. 2004
    ..Epidemiological studies contribute to all stages of development of vaccine evaluation and introduction...
  12. pmc Assessment and comparative analysis of a rapid diagnostic test (Tubex®) for the diagnosis of typhoid fever among hospitalized children in rural Tanzania
    Benedikt Ley
    Translational Research Division, International Vaccine Institute, Seoul, Korea
    BMC Infect Dis 11:147. 2011
    ..A rapid diagnostic test for typhoid fever, Tubex®, is commercially available that uses particle separation to detect immunoglobulin M directed towards Salmonella Typhi O9 lipopolysaccharide in sera...
  13. ncbi Implementation of good clinical practice guidelines in vaccine trials in developing countries
    Camilo J Acosta
    International Vaccine Institute, Seoul, Republic of Korea
    Vaccine 25:2852-7. 2007
    ..The ICH GCP principles are discussed below within the framework of this recent typhoid fever vaccine study experience...
  14. pmc Community participation in two vaccination trials in slums of Kolkata, India: a multi-level analysis
    Mohammad Ali
    International Vaccine Institute, Seoul, Korea
    J Health Popul Nutr 28:450-7. 2010
    ..The results illustrated that participation in the trial was mostly influenced by various individual and community-level factors, which need to be addressed for a successful vaccination campaign...
  15. doi Typhoid vaccination: the Asian experience
    Denise DeRoeck
    Social Science Research and Institutional Development, International Vaccine Institute, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul 151 818, Republic of Korea
    Expert Rev Vaccines 7:547-60. 2008
    ..This review also describes recent typhoid Vi vaccine demonstration projects that were conducted in five Asian countries...
  16. doi Population impact of Vi capsular polysaccharide vaccine
    M Imran Khan
    International Vaccine Institute, Seoul, 151 919, Republic of Korea
    Expert Rev Vaccines 9:485-96. 2010
    ..The large-scale use of this vaccine can yield protective benefits to a larger population and can reduce the epidemiologic and economic burden of typhoid fever in endemic countries...
  17. doi Impact of Vi vaccination on spatial patterns of typhoid fever in the slums of Kolkata, India
    Mohammad Ali
    International Vaccine Institute, Gwanak Gu, Seoul, Republic of Korea
    Vaccine 29:9051-6. 2011
    ..Understanding and mapping the disease risk could be useful for designing a community-based vaccination strategy to control disease...
  18. ncbi Isolation of Salmonella enterica subspecies enterica serovar Paratyphi B dT+, or Salmonella Java, from Indonesia and alteration of the d-tartrate fermentation phenotype by disrupting the ORF STM 3356
    Kyung Ho Han
    International Vaccine Institute, San 4 8 Bongcheon 7 Dong, Kwanak gu, Seoul, 151 818, Republic of Korea
    J Med Microbiol 55:1661-5. 2006
    ..The results show that the dT+ phenotype requires a functional product encoded by STM 3356, and support the use of the PCR-based discrimination method for S. Paratyphi B and S. Java as the standard differentiation method...
  19. pmc Evaluation of the Widal tube agglutination test for the diagnosis of typhoid fever among children admitted to a rural hdospital in Tanzania and a comparison with previous studies
    Benedikt Ley
    International Vaccine Institute, Seoul, Korea
    BMC Infect Dis 10:180. 2010
    ..typhi). However, a more rapid, simpler, and cheaper diagnostic method would be very useful especially in developing countries. The Widal test is widely used in Africa but little information exists about its reliability...
  20. ncbi Efficacy of a locally produced, Chinese Vi polysaccharide typhoid fever vaccine during six years of follow-up
    Camilo J Acosta
    International Vaccine Institute, SNU Research Park, San 4 8 Bong Cheon 7 Dong Kwanak Ku, Seoul 151 818, South Korea
    Vaccine 23:5618-23. 2005
    ..These results confirm that this vaccine protects for at least 2 years, and are consistent with the assertion that the vaccine protects for at least 3 years...
  21. doi Emergence of highly fluoroquinolone-resistant Salmonella enterica serovar Typhi in a community-based fever surveillance from Kolkata, India
    Shanta Dutta
    Int J Antimicrob Agents 31:387-9. 2008
  22. ncbi The feasibility of a school-based VI polysaccharide vaccine mass immunization campaign in Hue City, central Vietnam: streamlining a typhoid fever preventive strategy
    Vu Dinh Thiem
    National Institute of Hygiene and Epidemiology, Hanoi, People s Republic of Vietnam
    Southeast Asian J Trop Med Public Health 37:515-22. 2006
    ..The lessons learned, together with cost-effectiveness results to be obtained by the end of follow-up period, will hopefully accelerate the introduction of Vi typhoid fever vaccine in Vietnam...
  23. pmc Adults' perceived prevalence of enteric fever predicts laboratory-validated incidence of typhoid fever in children
    Xinguang Chen
    Carman and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI 48201, USA
    J Health Popul Nutr 25:469-78. 2007
    ..01; R2=0.992). Using adults' perception of prevalence of disease as the basis for estimating its incidence in children provides a cost-effective behavioural epidemiologic method to facilitate prevention and control of the disease...
  24. ncbi The malaria and typhoid fever burden in the slums of Kolkata, India: data from a prospective community-based study
    Dipika Sur
    National Institute of Cholera and Enteric Diseases, P 33 CIT Rd Scheme XM, Beliaghata, Kolkata 700010, India
    Trans R Soc Trop Med Hyg 100:725-33. 2006
    ..Focal interventions to minimise human-vector contact and improved personal hygiene and targeted vaccination campaigns could help to prevent malaria and typhoid fever in this site...
  25. pmc Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones
    Tran Thuy Chau
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, Ho Chi Minh City, Vietnam
    Antimicrob Agents Chemother 51:4315-23. 2007
    ..The 8-methoxy fluoroquinolone gatifloxacin showed rapid killing of serovar Typhi harboring both the single- and double-amino-acid substitutions...