P A Thomas

Summary

Country: India

Publications

  1. pmc Spectrum of bacterial keratitis at a tertiary eye care centre in India
    Jayaraman Kaliamurthy
    Department of Ocular Microbiology, Institute of Ophthalmology, Joseph Eye Hospital, Trichy, Tamil Nadu 620001, India
    Biomed Res Int 2013:181564. 2013
  2. pmc Expression of genes of the aflatoxin biosynthetic pathway in Aspergillus flavus isolates from keratitis
    George Leema
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tamil Nadu, India
    Mol Vis 17:2889-97. 2011
  3. pmc Keratitis due to Chaetomium sp
    Jayaraman Kaliamurthy
    Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli 620 001, India
    Case Rep Ophthalmol Med 2011:696145. 2011
  4. doi request reprint PCR for the molecular diagnosis of mycotic keratitis
    Philip A Thomas
    Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli 620001, India
    Expert Rev Mol Diagn 12:703-18. 2012
  5. ncbi request reprint Mycotic keratitis: epidemiology, diagnosis and management
    P A Thomas
    Department of Ocular Microbiology, Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli, India
    Clin Microbiol Infect 19:210-20. 2013
  6. doi request reprint Pleurotus ostreatus, an oyster mushroom, decreases the oxidative stress induced by carbon tetrachloride in rat kidneys, heart and brain
    T Jayakumar
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu, India
    Chem Biol Interact 176:108-20. 2008
  7. doi request reprint Green tea catechins, alleviate hepatic lipidemic-oxidative injury in Wistar rats fed an atherogenic diet
    E Ramesh
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India
    Chem Biol Interact 180:10-9. 2009
  8. ncbi request reprint Acetyl-L-carnitine prevents selenite-induced cataractogenesis in an experimental animal model
    R Elanchezhian
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tamil Nadu, India
    Curr Eye Res 32:961-71. 2007
  9. doi request reprint Anticataractogenic effect of an extract of the oyster mushroom, Pleurotus ostreatus, in an experimental animal model
    M Isai
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India
    Curr Eye Res 34:264-73. 2009
  10. doi request reprint Epigallocatechin gallate improves serum lipid profile and erythrocyte and cardiac tissue antioxidant parameters in Wistar rats fed an atherogenic diet
    E Ramesh
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India
    Fundam Clin Pharmacol 22:275-84. 2008

Collaborators

  • E Ramesh
  • P Geraldine
  • R Elanchezhian
  • M Sakthivel
  • M Isai
  • T Annadurai
  • Jayaraman Kaliamurthy
  • J Kaliamurthy
  • C Nelson Jesudasan
  • George Leema
  • M Rajamohan
  • T Jayakumar
  • A Salman
  • C M Kalavathy
  • P Parmar
  • C A Nelson Jesudasan
  • Catti Muniswamy Kalavathy
  • Pragya Parmar
  • Christadas Arul Nelson Jesudasan
  • A R Muralidharan
  • T Joseph
  • M J Hsu
  • Christadoss Arul Nelson Jesudasan
  • Duen Suey Chou
  • Catti Munuswamy Kalavathy
  • Pitchairaj Geraldine
  • Christadoss A Nelson Jesudasan
  • A Chinnakkaruppan
  • C G Vanila
  • B Brijit Sneha

Detail Information

Publications24

  1. pmc Spectrum of bacterial keratitis at a tertiary eye care centre in India
    Jayaraman Kaliamurthy
    Department of Ocular Microbiology, Institute of Ophthalmology, Joseph Eye Hospital, Trichy, Tamil Nadu 620001, India
    Biomed Res Int 2013:181564. 2013
    ..To report the aetiological spectrum and susceptibility patterns of bacteria isolated from patients with corneal ulceration...
  2. pmc Expression of genes of the aflatoxin biosynthetic pathway in Aspergillus flavus isolates from keratitis
    George Leema
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tamil Nadu, India
    Mol Vis 17:2889-97. 2011
    ..To document transcriptional activation (expression) of key aflatoxin biosynthetic pathway genes in corneal isolates of Aspergillus flavus...
  3. pmc Keratitis due to Chaetomium sp
    Jayaraman Kaliamurthy
    Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli 620 001, India
    Case Rep Ophthalmol Med 2011:696145. 2011
    ..Conclusion. Fungi of the genus Chaetomium, which are rare causes of human disease (systemic mycosis, endocarditis, subcutaneous lesions), may also cause ocular lesions...
  4. doi request reprint PCR for the molecular diagnosis of mycotic keratitis
    Philip A Thomas
    Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli 620001, India
    Expert Rev Mol Diagn 12:703-18. 2012
    ..An expert assessment is also made of studies that have used PCR for the diagnosis of mycotic keratitis. The review concludes with a Five-year view of the potential impact of PCR in management of mycotic keratitis...
  5. ncbi request reprint Mycotic keratitis: epidemiology, diagnosis and management
    P A Thomas
    Department of Ocular Microbiology, Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli, India
    Clin Microbiol Infect 19:210-20. 2013
    ..Therapeutic surgery, such as therapeutic penetrating keratoplasty, is needed when medical therapy fails. Increased awareness of the importance of this condition is likely to spur future research initiatives...
  6. doi request reprint Pleurotus ostreatus, an oyster mushroom, decreases the oxidative stress induced by carbon tetrachloride in rat kidneys, heart and brain
    T Jayakumar
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu, India
    Chem Biol Interact 176:108-20. 2008
    ..ostreatus. These results suggest that an extract of P. ostreatus is able to alleviate the oxidative damage caused by CCl4 in the kidneys, heart and brain of Wistar rats...
  7. doi request reprint Green tea catechins, alleviate hepatic lipidemic-oxidative injury in Wistar rats fed an atherogenic diet
    E Ramesh
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India
    Chem Biol Interact 180:10-9. 2009
    ..These results suggest that EGCG as a major component of green tea catechins may protect against the hepatic abnormalities occurring in Wistar rats fed an atherogenic diet...
  8. ncbi request reprint Acetyl-L-carnitine prevents selenite-induced cataractogenesis in an experimental animal model
    R Elanchezhian
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tamil Nadu, India
    Curr Eye Res 32:961-71. 2007
    ..To investigate whether acetyl-L-carnitine (ALCAR) retards selenite-induced cataractogenesis in vivo...
  9. doi request reprint Anticataractogenic effect of an extract of the oyster mushroom, Pleurotus ostreatus, in an experimental animal model
    M Isai
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India
    Curr Eye Res 34:264-73. 2009
    ..To evaluate the efficacy of Pleurotus ostreatus extract in preventing selenite-induced cataractogenesis...
  10. doi request reprint Epigallocatechin gallate improves serum lipid profile and erythrocyte and cardiac tissue antioxidant parameters in Wistar rats fed an atherogenic diet
    E Ramesh
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India
    Fundam Clin Pharmacol 22:275-84. 2008
    ..Thus, EGCG appears to ameliorate disruptions of serum lipid profile and of antioxidant parameters in erythrocyte and cardiac tissue of Wistar rats fed an atherogenic diet; these results may be relevant to treating human atherosclerosis...
  11. ncbi request reprint Prevention of selenite-induced cataractogenesis in Wistar rats by the polyphenol, ellagic acid
    M Sakthivel
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India
    Exp Eye Res 86:251-9. 2008
    ..This protective effect in rat lenses appears to occur by maintaining the antioxidant defense system and inhibition of lipid peroxidation...
  12. pmc Prevention of selenite-induced cataractogenesis by rutin in Wistar rats
    M Isai
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tamil Nadu, India
    Mol Vis 15:2570-7. 2009
    ..To investigate whether rutin retards selenite-induced cataractogenesis in Wistar rat pups...
  13. pmc Evaluation of lenticular antioxidant and redox system components in the lenses of acetyl-L-carnitine treatment in BSO-induced glutathione deprivation
    R Elanchezhian
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tamil Nadu, India
    Mol Vis 15:1485-91. 2009
    ..To investigate whether acetyl-L-carnitine (ALCAR) retards L-buthionine-(S,R)-sulfoximine (BSO)-induced cataractogenesis in Wistar rat pups...
  14. doi request reprint Regulatory effect of acetyl-l-carnitine on expression of lenticular antioxidant and apoptotic genes in selenite-induced cataract
    R Elanchezhian
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu, India
    Chem Biol Interact 184:346-51. 2010
    ..These results suggest that ALCAR may prevent selenite-induced cataractogenesis by preventing abnormal expression of lenticular genes governing apoptosis...
  15. doi request reprint The effect of acetyl-L-carnitine on lenticular calpain activity in prevention of selenite-induced cataractogenesis
    R Elanchezhian
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tamil Nadu, India
    Exp Eye Res 88:938-44. 2009
    ..These findings may stimulate further efforts to develop ALCAR as a novel drug for prevention of cataract...
  16. doi request reprint Regulatory effect of epigallocatechin gallate on the expression of C-reactive protein and other inflammatory markers in an experimental model of atherosclerosis
    E Ramesh
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620 024, Tamil Nadu, India
    Chem Biol Interact 183:125-32. 2010
    ..These results suggest that EGCG, a major component of green tea catechins, may decrease the risk of cardiovascular disease by reducing inflammatory markers in rats fed an atherogenic diet...
  17. ncbi request reprint Prevention of selenite-induced cataractogenesis by acetyl-L-carnitine: an experimental study
    P Geraldine
    Department of Animal Science, Bharathidasan University, Tiruchirapalli, India
    Exp Eye Res 83:1340-9. 2006
    ..5% of those receiving subcutaneous selenite and intraperitoneal ALCAR. These data suggest that ALCAR is able to significantly retard experimental selenite-induced cataractogenesis...
  18. ncbi request reprint Ameliorative effect of naringenin on hyperglycemia-mediated inflammation in hepatic and pancreatic tissues of Wistar rats with streptozotocin- nicotinamide-induced experimental diabetes mellitus
    T Annadurai
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India
    Free Radic Res 47:793-803. 2013
    ..These results suggest that naringenin possibly alleviates hyperglycemia-mediated inflammation in experimental STZ-nicotinamide-induced DM in Wistar rats...
  19. doi request reprint Antihyperglycemic and antioxidant effects of a flavanone, naringenin, in streptozotocin-nicotinamide-induced experimental diabetic rats
    T Annadurai
    Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli 620024 Tamil Nadu, India
    J Physiol Biochem 68:307-18. 2012
    ..These results suggest that naringenin exhibits antihyperglycemic and antioxidant effects in experimental diabetic rats...
  20. ncbi request reprint Disseminated aspergillosis due to Aspergillus flavus in an experimental model: efficacy of azole therapy
    J Kaliamurthy
    Department of Microbiology, Joseph Eye Hospital, Bharathidasan University, Tiruchirappalli, India
    Mycoses 46:174-82. 2003
    ..These data suggest that administration of itraconazole or fluconazole sufficiently early may prevent, or retard, progression of lesions in disseminated aspergillosis...
  21. ncbi request reprint Comparison of in vitro susceptibilities of ocular bacterial isolates to gatifloxacin and other topical antibiotics
    J Kaliamurthy
    Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli, India
    Ophthalmic Res 37:117-22. 2005
    ..To compare the in vitro activity of gatifloxacin with that of other topical antibiotics against fresh bacterial isolates from various types of human ocular infections...
  22. ncbi request reprint Fungal infections of the cornea
    P A Thomas
    Department of Microbiology, Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli, India
    Eye (Lond) 17:852-62. 2003
    ..To describe key aspects of fungal infections of the cornea, which constitute an important eye problem in outdoor workers in tropical and subtropical regions...
  23. ncbi request reprint Is ultrasonography essential before surgery in eyes with advanced cataracts?
    A Salman
    The Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirapalli 620 001, India
    J Postgrad Med 52:19-22. 2006
    ..Ultrasonography is an important tool for evaluating the posterior segment in eyes with opaque media...