Leelakumari Sreeja

Summary

Country: India

Publications

  1. ncbi request reprint Prognostic importance of DNA repair gene polymorphisms of XRCC1 Arg399Gln and XPD Lys751Gln in lung cancer patients from India
    Leelakumari Sreeja
    Division of Cancer Research, Regional Cancer Centre, Trivandrum, Kerala 695011, India
    J Cancer Res Clin Oncol 134:645-52. 2008
  2. ncbi request reprint Glutathione S-transferase M1, T1 and P1 polymorphisms: susceptibility and outcome in lung cancer patients
    Leelakumari Sreeja
    Division of Cancer Research, Regional Cancer Centre, Trivandrum 695011, India
    J Exp Ther Oncol 7:73-85. 2008
  3. ncbi request reprint Influence of germline polymorphisms of GSTT1, GSTM1, and GSTP1 in familial versus sporadic breast cancer susceptibility and survival
    Volga S Syamala
    Division of Cancer Research, Regional Cancer Centre, Trivandrum, 695011, Kerala, India
    Fam Cancer 7:213-20. 2008
  4. ncbi request reprint Hereditary breast/ovarian cancer: clinicopathological characteristics and survival of BRCA2 positive and negative cases
    Vani Syamala
    Division of Cancer Research, Regional Cancer Centre, Thiruvananthapuram 695011, Kerala, India
    J Exp Ther Oncol 7:227-36. 2008
  5. doi request reprint p53 Arg72Pro polymorphism predicts survival outcome in lung cancer patients in Indian population
    Leelakumari Sreeja
    Division of Cancer Research, Regional Cancer Centre, Kerala, India
    Cancer Invest 26:41-6. 2008
  6. ncbi request reprint Novel germline mutations in BRCA2 gene among 96 hereditary breast and breast-ovarian cancer families from Kerala, South India
    Vani Syamala
    Division of Cancer Research, Regional Cancer Centre, Thiruvananthapuram, Kerala, 695011, India
    J Cancer Res Clin Oncol 133:867-74. 2007
  7. ncbi request reprint Possible risk modification by CYP1A1, GSTM1 and GSTT1 gene polymorphisms in lung cancer susceptibility in a South Indian population
    Leelakumari Sreeja
    Division of Cancer Research, Regional Cancer Centre, Thiruvananthapuram, Kerala, 695011, India
    J Hum Genet 50:618-27. 2005

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Prognostic importance of DNA repair gene polymorphisms of XRCC1 Arg399Gln and XPD Lys751Gln in lung cancer patients from India
    Leelakumari Sreeja
    Division of Cancer Research, Regional Cancer Centre, Trivandrum, Kerala 695011, India
    J Cancer Res Clin Oncol 134:645-52. 2008
    ..Two of the genetic polymorphisms, XRCC1Arg399Gln and XPD Lys751Gln have been extensively studied in the association with lung cancer risk, although published studies have been inconclusive...
  2. ncbi request reprint Glutathione S-transferase M1, T1 and P1 polymorphisms: susceptibility and outcome in lung cancer patients
    Leelakumari Sreeja
    Division of Cancer Research, Regional Cancer Centre, Trivandrum 695011, India
    J Exp Ther Oncol 7:73-85. 2008
    ..The GSTT1 -/- genotype along with stage was significantly associated with overall survival and found to be an independent prognostic factors for shorter lung cancer survival...
  3. ncbi request reprint Influence of germline polymorphisms of GSTT1, GSTM1, and GSTP1 in familial versus sporadic breast cancer susceptibility and survival
    Volga S Syamala
    Division of Cancer Research, Regional Cancer Centre, Trivandrum, 695011, Kerala, India
    Fam Cancer 7:213-20. 2008
    ..It is also noticed that all the polymorphisms associated with sporadic breast cancer are not associated with familial breast cancer...
  4. ncbi request reprint Hereditary breast/ovarian cancer: clinicopathological characteristics and survival of BRCA2 positive and negative cases
    Vani Syamala
    Division of Cancer Research, Regional Cancer Centre, Thiruvananthapuram 695011, Kerala, India
    J Exp Ther Oncol 7:227-36. 2008
    ..Patients with hereditary breast/ovarian cancer resulting from a BRCA2 mutation have been conclusively shown to have a worse survival prognosis compared to the non mutated group of patients...
  5. doi request reprint p53 Arg72Pro polymorphism predicts survival outcome in lung cancer patients in Indian population
    Leelakumari Sreeja
    Division of Cancer Research, Regional Cancer Centre, Kerala, India
    Cancer Invest 26:41-6. 2008
    ..2; P = 0.02), suggesting Pro72Pro genotype to be a potential risk factor favoring the development of lung carcinoma and that Arg72Pro genotype is independently associated with a poorer prognosis of lung cancer...
  6. ncbi request reprint Novel germline mutations in BRCA2 gene among 96 hereditary breast and breast-ovarian cancer families from Kerala, South India
    Vani Syamala
    Division of Cancer Research, Regional Cancer Centre, Thiruvananthapuram, Kerala, 695011, India
    J Cancer Res Clin Oncol 133:867-74. 2007
    ..Aim of the present study was to identify the genetic heterogeneity, prevalence and frequency of germline mutations of BRCA2 gene in Hereditary Breast/Ovarian cancer patients from Kerala, South India...
  7. ncbi request reprint Possible risk modification by CYP1A1, GSTM1 and GSTT1 gene polymorphisms in lung cancer susceptibility in a South Indian population
    Leelakumari Sreeja
    Division of Cancer Research, Regional Cancer Centre, Thiruvananthapuram, Kerala, 695011, India
    J Hum Genet 50:618-27. 2005
    ..Hence our study-the first to analyse a South Indian population-suggests the importance of combined CYP1A1, GSTM1 and GSTT1 polymorphisms in the development of smoking-induced lung cancer...