Ramendra K Singh

Summary

Country: India

Publications

  1. ncbi request reprint Anti-HIV drug development: structural features and limitations of present day drugs and future challenges in the successful HIV/AIDS treatment
    Garima Kumari
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211002, India
    Curr Pharm Des 19:1767-83. 2013
  2. ncbi request reprint Curcumin bioconjugates: studies on structure-activity relationship and antibacterial properties against clinically isolated strains
    Diwakar Rai
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211002, India
    Med Chem 9:999-1005. 2013
  3. doi request reprint Synthesis, structure-activity relationship and antiviral activity of 3'-N,N-dimethylamino-2',3'-dideoxythymidine and its prodrugs
    Ramendra K Singh
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211002, India
    Eur J Med Chem 45:3787-93. 2010
  4. doi request reprint Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid
    Ramendra K Singh
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211002, India
    Eur J Med Chem 45:1078-86. 2010
  5. ncbi request reprint Synthesis and antimicrobial activity of some novel nucleoside analogues of adenosine and 1,3-dideazaadenosine
    Richa Srivastava
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211 002, India
    Bioorg Med Chem Lett 17:6239-44. 2007
  6. doi request reprint Rhodium(II) acetate-catalyzed stereoselective synthesis, SAR and anti-HIV activity of novel oxindoles bearing cyclopropane ring
    Garima Kumari
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211002, India
    Eur J Med Chem 46:1181-8. 2011
  7. ncbi request reprint Synthesis and antiviral properties of arabino and ribonucleosides of 1,3-dideazaadenine, 4-nitro-1,3-dideazapurine and diketopiperazine
    Sarika Sinha
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad, India
    Nucleosides Nucleotides Nucleic Acids 23:1815-24. 2004
  8. ncbi request reprint Some novel adenosine mimics: synthesis and anticancer potential against cervical cancer caused by human papilloma virus
    Sarika Sinha
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad, India
    Nucleosides Nucleotides Nucleic Acids 26:773-7. 2007

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Anti-HIV drug development: structural features and limitations of present day drugs and future challenges in the successful HIV/AIDS treatment
    Garima Kumari
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211002, India
    Curr Pharm Des 19:1767-83. 2013
    ....
  2. ncbi request reprint Curcumin bioconjugates: studies on structure-activity relationship and antibacterial properties against clinically isolated strains
    Diwakar Rai
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211002, India
    Med Chem 9:999-1005. 2013
    ..Thus, the bioconjugate 2, having folic acid attached at active methylene site of curcumin with free phenolic hydroxyls, showed the best result. ..
  3. doi request reprint Synthesis, structure-activity relationship and antiviral activity of 3'-N,N-dimethylamino-2',3'-dideoxythymidine and its prodrugs
    Ramendra K Singh
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211002, India
    Eur J Med Chem 45:3787-93. 2010
    ..Molecular docking studies with HIV-1 RT using DS 2.5 and pymol softwares have shown marked differences in the interaction patterns between the lead compound 4 and AZT...
  4. doi request reprint Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid
    Ramendra K Singh
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211002, India
    Eur J Med Chem 45:1078-86. 2010
    ..011 microM and 0.029 microM against VSV and FIPV/FHV, respectively. However, the molecules did not show expected results against HIV-1 III(B) and ROD strains in MTT assay...
  5. ncbi request reprint Synthesis and antimicrobial activity of some novel nucleoside analogues of adenosine and 1,3-dideazaadenosine
    Richa Srivastava
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211 002, India
    Bioorg Med Chem Lett 17:6239-44. 2007
    ..Further, the results suggest that the molecules 4, 6, and 7 would be potent antifungal agents as they show substantial degree of inhibition toward the growth of pathogenic fungi with MICs of 0.75, 0.38, and 0.38 microM, respectively...
  6. doi request reprint Rhodium(II) acetate-catalyzed stereoselective synthesis, SAR and anti-HIV activity of novel oxindoles bearing cyclopropane ring
    Garima Kumari
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad 211002, India
    Eur J Med Chem 46:1181-8. 2011
    ....
  7. ncbi request reprint Synthesis and antiviral properties of arabino and ribonucleosides of 1,3-dideazaadenine, 4-nitro-1,3-dideazapurine and diketopiperazine
    Sarika Sinha
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad, India
    Nucleosides Nucleotides Nucleic Acids 23:1815-24. 2004
    ..It was observed that arabinosides had greater inhibitory action than ribosides. The compound 7 or Ara-NDDP has shown maximum inhibition of HIV-1 replication than the rest of the molecules with an IC50 of 79.4 microg/mL...
  8. ncbi request reprint Some novel adenosine mimics: synthesis and anticancer potential against cervical cancer caused by human papilloma virus
    Sarika Sinha
    Nucleic Acids Research Laboratory, Department of Chemistry, University of Allahabad, Allahabad, India
    Nucleosides Nucleotides Nucleic Acids 26:773-7. 2007
    ....