Asha Misra

Summary

Affiliation: Sanjay Gandhi Postgraduate Institute of Medical Sciences
Country: India

Publications

  1. pmc Gastric adenocarcinoma in a patient re-infected with H. pylori after regression of MALT lymphoma with successful anti-H. pylori therapy and gastric resection: a case report
    Uday C Ghoshal
    Department of Gastroenterology, Seth Sukhlal Karnani Memorial Hospital and Institute of Postgraduate Medical Education and Research, 244, AJC Bose Road, Kolkata 700020, India
    BMC Gastroenterol 2:6. 2002
  2. ncbi request reprint Strongyloides stercoralis infestation in a patient with severe ulcerative colitis
    Uday C Ghoshal
    Department of Gastroenterology, Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    Indian J Med Sci 60:106-10. 2006
  3. ncbi request reprint Interleukin-10 (-819 C/T) and tumor necrosis factor-alpha (-308 G/A) gene variants influence gastritis and lymphoid follicle development
    B R Achyut
    Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    Dig Dis Sci 53:622-9. 2008
  4. ncbi request reprint Epidemiological and clinical profile of irritable bowel syndrome in India: report of the Indian Society of Gastroenterology Task Force
    Uday C Ghoshal
    Department of Gastroenterology, SGPGI, Lucknow
    Indian J Gastroenterol 27:22-8. 2008
  5. ncbi request reprint Relationship of severity of gastroesophageal reflux disease with gastric acid secretory profile and esophageal acid exposure during nocturnal acid breakthrough: a study using 24-h dual-channel pH-metry
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Scand J Gastroenterol 43:654-61. 2008
  6. pmc Recurrent lower gastrointestinal bleeding from idiopathic ileocolonic varices: a case report
    Ravula Phani Krishna
    Department of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India
    J Med Case Reports 4:257. 2010
  7. pmc Spectrum and antibiotic sensitivity of bacteria contaminating the upper gut in patients with malabsorption syndrome from the tropics
    Ujjala Ghoshal
    Department of Microbiology Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow 226014, India
    BMC Gastroenterol 3:9. 2003
  8. ncbi request reprint Utility of hydrogen breath tests in diagnosis of small intestinal bacterial overgrowth in malabsorption syndrome and its relationship with oro-cecal transit time
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 25:6-10. 2006
  9. ncbi request reprint Malnutrition in inflammatory bowel disease patients in northern India: frequency and factors influencing its development
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, India
    Trop Gastroenterol 29:95-7. 2008
  10. ncbi request reprint Anti-Saccharomyces cerevisiae antibody is not useful to differentiate between Crohn's disease and intestinal tuberculosis in India
    U C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    J Postgrad Med 53:166-70. 2007

Collaborators

Detail Information

Publications91

  1. pmc Gastric adenocarcinoma in a patient re-infected with H. pylori after regression of MALT lymphoma with successful anti-H. pylori therapy and gastric resection: a case report
    Uday C Ghoshal
    Department of Gastroenterology, Seth Sukhlal Karnani Memorial Hospital and Institute of Postgraduate Medical Education and Research, 244, AJC Bose Road, Kolkata 700020, India
    BMC Gastroenterol 2:6. 2002
    ..Helicobacter pylori (H. pylori) has been etiologically linked with primary gastric lymphoma (PGL) and gastric carcinoma (GC). There are a few reports of occurrence of both diseases in the same patients with H. pylori infection...
  2. ncbi request reprint Strongyloides stercoralis infestation in a patient with severe ulcerative colitis
    Uday C Ghoshal
    Department of Gastroenterology, Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    Indian J Med Sci 60:106-10. 2006
    ..Difficulties in diagnosis and management of Strongyloides stercoralis infestation in patients with UC are discussed...
  3. ncbi request reprint Interleukin-10 (-819 C/T) and tumor necrosis factor-alpha (-308 G/A) gene variants influence gastritis and lymphoid follicle development
    B R Achyut
    Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    Dig Dis Sci 53:622-9. 2008
    ..pylori infection than without (58.5% versus 22.2%; p = 0.064). IL-10 -819 T and TNF-alpha -308 A alleles may increase risk of gastritis and lymphoid follicle formation...
  4. ncbi request reprint Epidemiological and clinical profile of irritable bowel syndrome in India: report of the Indian Society of Gastroenterology Task Force
    Uday C Ghoshal
    Department of Gastroenterology, SGPGI, Lucknow
    Indian J Gastroenterol 27:22-8. 2008
    ..To study the profile of irritable bowel syndrome (IBS), and the frequency of such symptoms among the general population, in India...
  5. ncbi request reprint Relationship of severity of gastroesophageal reflux disease with gastric acid secretory profile and esophageal acid exposure during nocturnal acid breakthrough: a study using 24-h dual-channel pH-metry
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Scand J Gastroenterol 43:654-61. 2008
    ..The aims of this study were to investigate the relationship between gastric acid and the severity of GERD and the esophageal acidification and symptoms during NAB...
  6. pmc Recurrent lower gastrointestinal bleeding from idiopathic ileocolonic varices: a case report
    Ravula Phani Krishna
    Department of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India
    J Med Case Reports 4:257. 2010
    ..Idiopathic colonic varices are extremely rare. Recognition of this condition is important as idiopathic colonic varices may be a cause of recurrent lower gastrointestinal bleeding...
  7. pmc Spectrum and antibiotic sensitivity of bacteria contaminating the upper gut in patients with malabsorption syndrome from the tropics
    Ujjala Ghoshal
    Department of Microbiology Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow 226014, India
    BMC Gastroenterol 3:9. 2003
    ..Frequency, nature and antibiotic sensitivity of SIBO in patients with MAS are not well understood...
  8. ncbi request reprint Utility of hydrogen breath tests in diagnosis of small intestinal bacterial overgrowth in malabsorption syndrome and its relationship with oro-cecal transit time
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 25:6-10. 2006
    ..Quantitative culture of upper gut aspirate is used as a gold standard for the diagnosis of SIBO. Studies on diagnosis of SIBO using non-invasive hydrogen breath tests are contradictory...
  9. ncbi request reprint Malnutrition in inflammatory bowel disease patients in northern India: frequency and factors influencing its development
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, India
    Trop Gastroenterol 29:95-7. 2008
    ..Though there are several studies evaluating nutrition in patients with IBD from the developed world, the data from developing countries are scanty, where under nutrition is predominant...
  10. ncbi request reprint Anti-Saccharomyces cerevisiae antibody is not useful to differentiate between Crohn's disease and intestinal tuberculosis in India
    U C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    J Postgrad Med 53:166-70. 2007
    ..Anti- Saccharomyces cerevisiae antibody (ASCA), which is often present in the sera of patients with CD, may be potentially useful to differentiate CD from IT...
  11. pmc Models for prediction of mortality from cirrhosis with special reference to artificial neural network: a critical review
    Uday Chand Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226014, India
    Hepatol Int 2:31-8. 2008
    ..More studies are needed on ANN-based models for prediction of mortality of patients with cirrhosis of liver and its value in prioritization of organ allocation for treatment of patients with cirrhosis of liver...
  12. ncbi request reprint Colonic transit study by radio-opaque markers to investigate constipation: validation of a new protocol for a population with rapid gut transit
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, Uttar Pradesh, India
    Natl Med J India 20:225-9. 2007
    ....
  13. doi request reprint Frequency of Helicobacter pylori and CagA antibody in patients with gastric neoplasms and controls: the Indian enigma
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Dig Dis Sci 53:1215-22. 2008
    ..Despite association between H. pylori and gastric neoplasm (GN) from the developed world, studies from India, where infection is more common and acquired early, are scant and contradictory...
  14. ncbi request reprint Review of pathogenesis and management of constipation
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014
    Trop Gastroenterol 28:91-5. 2007
    ..Biofeedback is useful in faecal evacuation disorders. Surgery may also rarely be necessary to correct anatomical abnormalities...
  15. ncbi request reprint Antroduodenal manometry: experience from a tertiary care center
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Indian J Gastroenterol 27:53-7. 2008
    ..Though antroduodenal manometry (ADM) is an important research tool, experience on its clinical utility is scanty...
  16. ncbi request reprint Cholangiocarcinoma presenting with severe gastroparesis and pseudoachalasia
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow 226 014, India
    Indian J Gastroenterol 24:167-8. 2005
    ..Cholangiocarcinoma was detected on CT scan performed after the patient developed jaundice two months later. The lesion was deemed surgically unresectable. She died four months later...
  17. ncbi request reprint Esophageal motility changes after endoscopic intravariceal sclerotherapy with absolute alcohol
    U C Ghoshal
    Department of Gastroenterology, Seth Sukhlal Karnani Memorial Hospital and Institute of Postgraduate Medical Education and Research, 244, Acharya JC Bose Road, Calcutta 700020, India
    Dis Esophagus 13:148-51. 2000
    ..This study shows frequent occurrence of esophageal dysmotility after EST with AA; however, esophageal dysmotility after EST was infrequently associated with motor dysphagia...
  18. ncbi request reprint Pneumatic dilation versus intrasphincteric botulinum toxin injection in the treatment of achalasia cardia in India: an economic analysis
    U C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 21:193-6. 2002
    ..However, it is likely to be a costly treatment as repeated injections are often needed due to its short-lasting effect. No economic analysis of PD and BT strategies has been done in India...
  19. ncbi request reprint Tropical sprue is associated with contamination of small bowel with aerobic bacteria and reversible prolongation of orocecal transit time
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 18:540-7. 2003
    ..In tropical sprue (TS), response to antibiotics may suggest a role for bacterial contamination of the small bowel, which is known in diseases with prolonged orocecal transit time (OCTT)...
  20. ncbi request reprint Management strategies for duodenal ulcer in India in the helicobacter pylori era: an economic analysis
    Uday C Ghoshal
    Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
    Natl Med J India 15:140-4. 2002
    ..Western investigators recommend initial empirical anti-H. pylori therapy for such patients. However, in India similar recommendations are lacking due to the absence of appropriate clinical studies...
  21. ncbi request reprint Randomized controlled trial of intrasphincteric botulinum toxin A injection versus balloon dilatation in treatment of achalasia cardia
    U C Ghoshal
    Department of Gastroenterology, Seth Sukhlal Karnani Memorial Hospital and Institute of Postgraduate Medical Education and Research, Calcutta, India
    Dis Esophagus 14:227-31. 2001
    ..It is also effective in patients with tortuous megaesophagus and previous failed pneumatic dilatation. However, dysphagia often recurs during 1-year follow up...
  22. ncbi request reprint Recurrent duodenal ulcer haemorrhage: a pharmacoeconomic comparison of various management strategies
    Uday Chand Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, India
    Expert Opin Pharmacother 4:1593-603. 2003
    ..Prevention of recurrence is, therefore, an important goal. Eradication of Helicobacter pylori or maintenance treatment with a proton pump inhibitor (PPI) may reduce recurrent DU bleeding. Economic comparison of these options is sparse...
  23. ncbi request reprint Strongyloides stercoralis infestation associated with septicemia due to intestinal transmural migration of bacteria
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, India
    J Gastroenterol Hepatol 17:1331-3. 2002
    ..This supports the hypothesis of migration of bacteria from the intestinal lumen as a cause of septicemia in patients with fulminant S. stercoralis infestation...
  24. ncbi request reprint Plasmodium falciparum and hepatitis E virus co-infection in fulminant hepatic failure
    U C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 20:111. 2001
    ..Peripheral smear was positive for Plasmodium falciparum, and IgM anti-HEV was positive. She died despite antimalarial drugs and supportive management. Postmortem liver tissue showed changes suggestive of acute viral hepatitis...
  25. ncbi request reprint Colonic mucosal changes in portal hypertension
    U C Ghoshal
    Department of Gastroenterology, Seth Sukhlal Karnani Memorial Hospital and Institute of Postgraduate Medical Education and Research, 244, Acharya JC Bose Road, Calcutta 700020, India
    Trop Gastroenterol 22:25-7. 2001
    ..Detection of colorectal varices but not portal hypertensive colopathy was associated with occurrence of hematochezia...
  26. pmc Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    BMC Gastroenterol 4:10. 2004
    ..A study described 15 cases of celiac disease unresponsive to GFD in whom small intestinal bacterial overgrowth (SIBO) or lactose intolerance was the cause for unresponsiveness...
  27. ncbi request reprint Is immunoproliferative small intestinal disease uncommon in India?
    U C Ghoshal
    Department of Gastroenterology, Institute of Postgraduate Medical Education and Research, 244, AJC Bose Road, Calcutta 700020
    Trop Gastroenterol 22:14-7. 2001
    ..One other patient was misdiagnosed and treated as intestinal tuberculosis. Early diagnosis and administration of chemotherapy may improve survival in this disease...
  28. ncbi request reprint Genotypic and functional roles of IL-1B and IL-1RN on the risk of gastroesophageal reflux disease: the presence of IL-1B-511*T/IL-1RN*1 (T1) haplotype may protect against the disease
    Dipti Chourasia
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
    Am J Gastroenterol 104:2704-13. 2009
    ....
  29. doi request reprint Abnormal small intestinal permeability in patients with idiopathic malabsorption in tropics (tropical sprue) does not change even after successful treatment
    Sunil Kumar
    Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow, 226014, India
    Dig Dis Sci 56:161-9. 2011
    ..Though tropical sprue (TS) is common in tropics, studies on small intestinal permeability (SIP) in TS are scant...
  30. ncbi request reprint Association of Toll-like receptor-4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions
    B R Achyut
    Department of Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Hum Immunol 68:901-7. 2007
    ..CagA positivity may be a risk factor for lymphoid follicle development but not for other precancerous lesions in a northern Indian population...
  31. pmc Spectrum of malabsorption syndrome among adults & factors differentiating celiac disease & tropical malabsorption
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Indian J Med Res 136:451-9. 2012
    ..This study was undertaken to investigate the spectrum of MAS among Indian adults and to find out the features that may help to differentiate between TM and celiac disease...
  32. ncbi request reprint Etiological spectrum of sporadic malabsorption syndrome in northern Indian adults at a tertiary hospital
    Piyush Ranjan
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 23:94-8. 2004
    ..CONCLUSIONS: Tropical sprue, celiac disease and Crohn's disease are common causes of MAS in Indian adults. Inappropriate anti-tubercular treatment is common in them and needs to be discouraged...
  33. doi request reprint Patients with Helicobacter pylori infection have less severe gastroesophageal reflux disease: a study using endoscopy, 24-hour gastric and esophageal pH metry
    Dipti Chourasia
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Indian J Gastroenterol 30:12-21. 2011
    ..We evaluated endoscopic, 24-h gastric and esophageal acid profile among patients with GERD in relation to H. pylori, as the latter might alter gastric acid secretion...
  34. doi request reprint Functional polymorphisms of cyclooxygenase-2 (COX-2) gene and risk for esophageal squmaous cell carcinoma
    Rohit Upadhyay
    Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Mutat Res 663:52-9. 2009
    ..Interaction of COX-2 -1195GA and -765C carrier genotypes also modulates ESCC risk...
  35. ncbi request reprint Evaluation of MTHFR677C>T polymorphism in prediction and prognosis of esophageal squamous cell carcinoma: a case-control study in a northern Indian population
    Meenakshi Umar
    Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareilly Road, Lucknow, India
    Nutr Cancer 62:743-9. 2010
    ..In conclusion, MTHFR677C>T polymorphism does not seem to have significant role either in susceptibility or survival of ESCC in a northern Indian population...
  36. doi request reprint CASP8 -652 6N del and CASP8 IVS12-19G>A gene polymorphisms and susceptibility/prognosis of ESCC: a case control study in northern Indian population
    Meenakshi Umar
    Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareilly Road, Lucknow, India
    J Surg Oncol 103:716-23. 2011
    ..Role of genetic variations in caspase8 has been explored in various cancers; however, their predictive and prognostic role in esophageal cancer is poorly understood...
  37. ncbi request reprint Lactose hydrogen breath test versus lactose tolerance test in the tropics: does positive lactose tolerance test reflect more severe lactose malabsorption?
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Trop Gastroenterol 30:86-90. 2009
    ..We compared the lactose hydrogen breath (lactose HBT) and lactose tolerance tests (LTT) in their ability to diagnose lactose malabsorption (LM)...
  38. ncbi request reprint Lactose intolerance in patients with irritable bowel syndrome from northern India: a case-control study
    Dinesh Gupta
    Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 22:2261-5. 2007
    ....
  39. pmc Polymorphism of -765G > C COX-2 is a risk factor for gastric adenocarcinoma and peptic ulcer disease in addition to H pylori infection: a study from northern India
    Ashish Saxena
    Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    World J Gastroenterol 14:1498-503. 2008
    ..To investigate -765G > C COX-2 polymorphism and H pylori infection in patients with gastric adenocarcinoma, peptic ulcer disease (PUD) and non-ulcer dyspepsia (NUD)...
  40. doi request reprint Gastric carcinogenesis: Possible role of polymorphisms of GSTM1, GSTT1, and GSTP1 genes
    Shweta Tripathi
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Scand J Gastroenterol 43:431-9. 2008
    ..The aim of this study was to investigate the role of polymorphisms of GSTM1, GSTT1, and GSTP1 genes, which encode for carcinogen-detoxifying enzymes, in gastric mutagenesis...
  41. doi request reprint Potential influence of interleukin-1 haplotype IL-1 beta-511*T-IL-1RN*1 in conferring low risk to middle third location of esophageal cancer: a case-control study
    Rohit Upadhyay
    Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raibareilly Road, Lucknow 226014, India
    Hum Immunol 69:179-86. 2008
    ..002; OR = 0.462; 95% CI = 0.253-0.845, p = 0.01). In conclusion, subjects with IL-1 beta -511TT genotype or IL-1 beta*T-IL-1RN*1 (T1) haplotype had lower risk for middle third tumor location of EC in a northern Indian population...
  42. doi request reprint Pneumatic dilation for achalasia cardia: reduction in lower esophageal sphincter pressure in assessing response and factors associated with recurrence during long-term follow up
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Dig Endosc 24:7-15. 2012
    ..Data on utility of post-pneumatic dilation (PD) lower esophageal sphincter (LES) pressure measurement in evaluating short and long-term efficacy of dilation, which tears the non-relaxing LES in achalasia, are scanty...
  43. ncbi request reprint Malabsorption syndrome due to various causes is associated with antroduodenal hypomotility
    Kshaunish Das
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Indian J Gastroenterol 25:58-61. 2006
    ..There are no data on antroduodenal manometry in malabsorption syndrome (MAS) due to causes other than celiac disease...
  44. doi request reprint Frequency and factors associated with small intestinal bacterial overgrowth in patients with cirrhosis of the liver and extra hepatic portal venous obstruction
    C P Lakshmi
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226014, India
    Dig Dis Sci 55:1142-8. 2010
    ..Patients with EHPVO do not have higher frequency of SIBO than healthy subjects. SIBO in cirrhosis is not related to the degree of derangement in liver function or of portal hypertension...
  45. doi request reprint Chronic diarrhea and malabsorption due to hypogammaglobulinemia: a report on twelve patients
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Indian J Gastroenterol 30:170-4. 2011
    ..Approximately 4% patients with MAS have hypogammaglobulinemia, which is often associated with infection and is diagnosed late...
  46. doi request reprint Capsule endoscopy for obscure gastrointestinal bleeding in the tropics: report from India
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Dig Endosc 23:17-23. 2011
    ..Capsule endoscopy (CE) is useful in patients with obscure gastrointestinal bleeding (OGIB). Experience in CE in OGIB in the tropics is limited...
  47. ncbi request reprint Malabsorption syndrome with and without small intestinal bacterial overgrowth: a study on upper-gut aspirate using 1H NMR spectroscopy
    Lakshmi Bala
    Center of Biomedical Magnetic Resonance, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Magn Reson Med 56:738-44. 2006
    ..05: 0.46 and 0.52, respectively). This study demonstrates the bacterial production of metabolites and deconjugation of bile acids in patients with MAS...
  48. ncbi request reprint Interaction of EGFR 497Arg>Lys with EGF +61A>G polymorphism: modulation of risk in esophageal cancer
    Rohit Upadhyay
    Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India
    Oncol Res 17:167-74. 2008
    ..In conclusion, EGF +61A>G gene polymorphisms influenced EC susceptibility and its clinical characteristics. Gene-gene interaction of EGFR 497Arg>Lys and EGF +61A>G polymorphisms enhanced risk for EC, indicating additive effects...
  49. doi request reprint Transforming growth factor-B1 and matrix metalloproteinase-7 promoter variants induce risk for Helicobacter pylori-associated gastric precancerous lesions
    B R Achyut
    Department of Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    DNA Cell Biol 28:295-301. 2009
    ..027, OR = 2.30). Thus, the present study revealed significant association of functional MMP-7 and TGF-B1 gene variants toward susceptibility to H. pylori-induced precancerous gastric lesions...
  50. ncbi request reprint Hepatitis E virus is responsible for decompensation of chronic liver disease in an endemic region
    Arvind Kumar
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226 014
    Indian J Gastroenterol 23:59-62. 2004
    ..Hepatitis A virus infection in patients with previously stable chronic liver disease is associated with liver decompensation. Whether infection with hepatitis E virus (HEV) also does so is not known...
  51. doi request reprint Lactose malabsorption diagnosed by 50-g dose is inferior to assess clinical intolerance and to predict response to milk withdrawal than 25-g dose in an endemic area
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 28:1462-8. 2013
    ..In LM-endemic areas, clinically significant malabsorption (lactose intolerance) may be better diagnosed using a lesser dose, and positive results so obtained may predict response to milk withdrawal more effectively...
  52. pmc Pathogenesis of tropical sprue: a pilot study of antroduodenal manometry, duodenocaecal transit time & fat-induced ileal brake
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Indian J Med Res 137:63-72. 2013
    ..We evaluated effect of infusion of fat or placebo in duodenum randomly in patients with TS and healthy controls on antroduodenal manometry (ADM) and mediators of ileal brake, and duodenocaecal transit time (DCTT)...
  53. ncbi request reprint Manometric and symptomatic spectrum of motor dysphagia in a tertiary referral center in northern India
    Asha Misra
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226 014, India
    Indian J Gastroenterol 29:12-6. 2010
    ..We studied the spectrum of motor dysphagia in a northern Indian tertiary referral center...
  54. ncbi request reprint GSTT1, GSTM1 and GSTP1 genetic polymorphisms and interaction with tobacco, alcohol and occupational exposure in esophageal cancer patients from North India
    Meenu Jain
    Department of Medical Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareily Road, Lucknow 226014, India
    Cancer Lett 242:60-7. 2006
    ..However, interaction of smoking or alcohol with GSTM1 null or GSTP1 ile/ile moderately increases the risk for esophageal cancer in North Indian population...
  55. doi request reprint Frequency of lactose malabsorption among healthy southern and northern Indian populations by genetic analysis and lactose hydrogen breath and tolerance tests
    Janaki Babu
    Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Am J Clin Nutr 91:140-6. 2010
    ..Lactose malabsorption (LM), the inability to break down lactose into glucose and galactose, is due to a deficiency in the small intestinal lactase phlorizin hydrolase enzyme. Ethnic and geographic variations of LM are known...
  56. pmc The enigma of Helicobacter pylori infection and gastric cancer
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Science, Lucknow, India
    Indian J Gastroenterol 29:95-100. 2010
    ..The mechanisms involved in reducing the risk of cancer in infected individuals are explored in this article, which may lead to the design of effective prevention strategies...
  57. ncbi request reprint Respiratory dysfunction is common in patients with achalasia and improves after pneumatic dilation
    Mahesh Gupta
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226014, India
    Dig Dis Sci 59:744-52. 2014
    ..Pneumatic dilation (PD) may improve pulmonary function. Data on pulmonary dysfunction among achalasia patients are scanty, and the effect of PD is unknown...
  58. ncbi request reprint Assessment of small intestinal permeability using 1H-NMR spectroscopy
    Kamaiah Jayalakshmi
    Centre of Biomedical Magnetic Resonance, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    J Gastrointestin Liver Dis 18:27-32. 2009
    ..Evaluation of small intestinal permeability (SIP) is based on the estimation of the urinary excretion ratio of a large and a small molecule (lactulose and mannitol, L/M) after oral administration. We evaluated SIP using 1H-NMR spectroscopy...
  59. doi request reprint Role of survivin gene promoter polymorphism (-31G>C) in susceptibility and survival of esophageal cancer in northern India
    Rohit Upadhyay
    Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Ann Surg Oncol 18:880-7. 2011
    ..We aim to explore the role of survivin -31G>C polymorphism in susceptibility and survival of EC patients in northern Indian population...
  60. doi request reprint Role of p53 and p73 genes polymorphisms in susceptibility to esophageal cancer: a case control study in a northern Indian population
    Meenakshi Umar
    Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareilly Road, Lucknow 226014, India
    Mol Biol Rep 39:1153-62. 2012
    ..In summary, p73 G4C14-to-A4T14 polymorphism but not the p53 intron3 16 bp duplication polymorphism is associated with EC and its clinical characteristics in northern Indian population...
  61. ncbi request reprint Primary gastric lymphoma and Helicobacter pylori infection with gastric amyloidosis
    Kshaunish Das
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 24:220-2. 2005
    ..pylori. Rectal biopsy was negative for amyloid. He remained well on follow-up after surgery and eradication of H. pylori...
  62. ncbi request reprint Gastric atrophy and intestinal metaplasia in a patient on long-term proton pump inhibitor therapy
    Dipti Chourasia
    Departments of Gastroenterology ABSTRACT and Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    Trop Gastroenterol 29:172-4. 2008
    ..76). The patient remained well after discontinuing proton pump inhibitors and continuing prokinetics and vitamin B12 injections...
  63. ncbi request reprint Manometric spectrum of fecal incontinence in a tertiary care center in northern India
    Arun T Korah
    Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226104, India
    Trop Gastroenterol 31:165-8. 2010
    ..Since, there is scanty data on manometric spectrum of fecal incontinence (FI) from India, ano-rectal manometry (ARM) parameters of patients with FI attending a tertiary care hospital were analyzed retrospectively...
  64. ncbi request reprint Causal role of Helicobacter pylori infection in gastric cancer: an Asian enigma
    Kartar Singh
    Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    World J Gastroenterol 12:1346-51. 2006
    ..Host's genetic make-up and dietary and environmental factors might explain this enigma. Studies are urgently needed to solve this issue...
  65. ncbi request reprint Role of BCL2 (ala43thr), CCND1 (G870A) and FAS (A-670G) polymorphisms in modulating the risk of developing esophageal cancer
    Meenu Jain
    Department of Medical Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareilly Road, Lucknow 226014, India
    Cancer Detect Prev 31:225-32. 2007
    ..A study of BCL2 ala43thr, CCND1 G870A and FAS A-670G gene polymorphisms was undertaken to explore their role in influencing the susceptibility for development of esophageal cancer...
  66. ncbi request reprint IL-1 receptor antagonist (IL-1Ra) gene polymorphism in patients with inflammatory bowel disease in India
    Rama D Mittal
    Department of Urology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
    Scand J Gastroenterol 40:827-31. 2005
    ....
  67. ncbi request reprint Infection with cytomegalovirus in patients with inflammatory bowel disease: prevalence, clinical significance and outcome
    Janak Kishore
    Departments of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    J Med Microbiol 53:1155-60. 2004
    ..003). CMV infection in patients with IBD may be common and is associated with poor outcome. PCR of rectal biopsy was the most sensitive method of detection followed by IgM antibody for diagnosis...
  68. ncbi request reprint Analysis of polymorphisms of tumor necrosis factor-alpha and polymorphic xenobiotic metabolizing enzymes in inflammatory bowel disease: study from northern India
    Rama D Mittal
    Department of Urology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
    J Gastroenterol Hepatol 22:920-4. 2007
    ..The present study aimed to evaluate the effect of polymorphism of the TNF-alpha promoter at the -308 site, GSTM1 and GSTT1 in patients with IBD and healthy controls from northern India...
  69. ncbi request reprint Assessment of cost-effectiveness of universal hepatitis B immunization in a low-income country with intermediate endemicity using a Markov model
    Rakesh Aggarwal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    J Hepatol 38:215-22. 2003
    ..We performed a cost-effectiveness analysis of universal childhood HB immunization in such countries using India as an example, since available data on this aspect are limited...
  70. doi request reprint Intestinal strongyloidiasis: a diagnosis frequently missed in the tropics
    Vinita Agrawal
    Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, Uttar Pradesh, India
    Trans R Soc Trop Med Hyg 103:242-6. 2009
    ..In endemic regions, patients with systemic Gram-negative bacterial infections without an obvious cause should be tested for strongyloidiasis...
  71. ncbi request reprint Small intestinal bacterial overgrowth is common both among patients with alcoholic and idiopathic chronic pancreatitis
    Kundan Kumar
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raibareily Road, Lucknow, UP 226014, India
    Pancreatology 14:280-3. 2014
    ..There are, however, scanty data on frequency of SIBO in patients with chronic idiopathic pancreatitis and factors associated with its occurrence...
  72. ncbi request reprint Breath tests in the diagnosis of small intestinal bacterial overgrowth in patients with irritable bowel syndrome in comparison with quantitative upper gut aspirate culture
    Uday C Ghoshal
    Departments of aGastroenterology bMicrobiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
    Eur J Gastroenterol Hepatol 26:753-60. 2014
    ..We also studied the clinical parameters that are associated with SIBO among them...
  73. ncbi request reprint Epstein-Barr virus DNA load and its association with Helicobacter pylori infection in gastroduodenal diseases
    Sanket Kumar Shukla
    Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Braz J Infect Dis 15:583-90. 2011
    ..Helicobacter pylori and Epstein-Barr virus (EBV) infections are common worldwide. Although H. pylori infection is a major factor in gastroduodenal diseases, its role in association with EBV infection is unknown...
  74. ncbi request reprint Pathogenesis of gastro-oesophageal reflux disease: what role do Helicobacter pylori and host genetic factors play?
    Dipti Chourasia
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Trop Gastroenterol 29:13-9. 2008
    ..There is scant data on the relationship between gastro-oesophageal reflux disease and H. pylori in India, and therefore, further studies are directly required to explore this issue...
  75. doi request reprint Bugs and irritable bowel syndrome: The good, the bad and the ugly
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 25:244-51. 2010
    ..How do we make sense of the apparently diverse roles that 'bugs' may play in IBS? To address this question, we have conducted an in-depth review, attempting where possible to draw lessons from Asian studies...
  76. ncbi request reprint Role of GSTM3 polymorphism in the risk of developing esophageal cancer
    Meenu Jain
    Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareilly Road, Lucknow 226014, India
    Cancer Epidemiol Biomarkers Prev 16:178-81. 2007
    ..2-5.6; P = 0.01) was also documented. Our results suggest that GSTM3 polymorphism may influence esophageal cancer susceptibility, in particular modulating the risk for adenocarcinoma histology and tumors of the mid and lower third region...
  77. ncbi request reprint Gastric adenocarcinoma presenting with intestinal pseudoobstruction, successfully treated with octreotide
    Sanjay Sharma
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Indian J Med Sci 60:467-70. 2006
    ..We report a 65-year-old man with carcinoma stomach presenting with intestinal pseudoobstruction, which responded to octreotide...
  78. pmc Physiological and functional evaluation of the transposed human pylorus as a distal sphincter
    Abhijit Chandra
    Department of Surgical Gastroenterology, CSM Medical University, Lucknow, India
    J Neurogastroenterol Motil 18:269-77. 2012
    ..This unique cohort of patients provided us an opportunity to study the sphincter properties of the pylorus in its ectopic position...
  79. pmc Frequency of small intestinal bacterial overgrowth in patients with irritable bowel syndrome and chronic non-specific diarrhea
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Post Graduate, Institute of Medical Sciences, Lucknow, India
    J Neurogastroenterol Motil 16:40-6. 2010
    ..Small intestinal bacterial overgrowth (SIBO) occurs in varying frequency in irritable bowel syndrome (IBS). We studied the frequency of SIBO in IBS and chronic non-specific diarrhea (CNSD)...
  80. ncbi request reprint Esophageal function tests in clinical practice: a review
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute Medical Sciences, Raebareli Road, Lucknow 226014, India
    Trop Gastroenterol 31:145-54. 2010
    ..Esophageal transit study is useful in understanding functional correlates of abnormalities in manometry and is particularly useful during follow up studies and in research...
  81. pmc Patients with irritable bowel syndrome exhale more hydrogen than healthy subjects in fasting state
    Sunil Kumar
    Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    J Neurogastroenterol Motil 16:299-305. 2010
    ....
  82. doi request reprint Association of interleukin-6 (-174G>C) promoter polymorphism with risk of squamous cell esophageal cancer and tumor location: an exploratory study
    Rohit Upadhyay
    Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareilly Road, Lucknow 226014, India
    Clin Immunol 128:199-204. 2008
    ..34; P=0.034). Patients having IL-6 -174C non-carrier genotype were at elevated risk of metastasis (OR=2.49; P=0.005). In conclusion, IL-6 -174G>C gene polymorphism may confer high risk for EC and its clinical characteristics...
  83. ncbi request reprint Helicobacter pylori-induced apoptosis in pathogenesis of gastric carcinoma
    Shridhar Tiwari
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
    Indian J Gastroenterol 24:193-6. 2005
    ..pylori and CagA antibody. Therefore, we studied gastric epithelial apoptosis in GC and non-ulcer dyspepsia (NUD) with or without H. pylori infection, and the degree of apoptosis in relation to CagA antibody status...
  84. ncbi request reprint Severe ulcerative colitis: prospective study of parameters determining outcome
    Sanjay Kumar
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 19:1247-52. 2004
    ..Although several studies have reported parameters associated with failure of medical treatment, studies using multivariate analysis of various predictors are scanty...
  85. ncbi request reprint Gut flora in health and small intestinal bacterial overgrowth syndrome
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    Trop Gastroenterol 28:140-2. 2007
  86. pmc Slow transit constipation associated with excess methane production and its improvement following rifaximin therapy: a case report
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences Lucknow, India
    J Neurogastroenterol Motil 17:185-8. 2011
    ....
  87. ncbi request reprint Colonoscopic management of roundworm in cecum
    Uday C Ghoshal
    Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226 014, India
    Indian J Gastroenterol 23:158. 2004
  88. doi request reprint Association of ECRG2 TCA short tandem repeat polymorphism with the risk of oesophageal cancer in a North Indian population
    Meenu Jain
    Department of Medical Genetics, Sanjay Gandhi Post Graduate, Institute of Medical Sciences, Raebareilly Road, Lucknow, 226014, India
    Clin Exp Med 8:73-8. 2008
    ..In conclusion, the ECRG2 TCA (3)/TCA (4) genotype is associated with the risk of oesophageal carcinoma in a North Indian population...
  89. ncbi request reprint CYP1A1 Msp1 T/C polymorphism in esophageal cancer: no association and risk modulation
    Meenu Jain
    Department of Medical Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India
    Oncol Res 16:437-43. 2007
    ..61-10.6, p = 0.19). In conclusion, CYP1A1 genotype did not influence the susceptibility of developing esophageal cancer. The presence of variant CYP1A1 genotypes together with environmental exposures also did not modulate the cancer risk...
  90. ncbi request reprint Influence of apoptosis (BCL2, FAS), cell cycle (CCND1) and growth factor (EGF, EGFR) genetic polymorphisms on survival outcome: an exploratory study in squamous cell esophageal cancer
    Meenu Jain
    Department of Medical Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Cancer Biol Ther 6:1553-8. 2007
    ..EGF +61AG genotype was associated with improved survival, however +61GG genotype adversely affected the outcome in patients particularly with upper third location of tumor and lower dose (< or =50) of radiotherapy...
  91. ncbi request reprint Infrequency of colonization with Oxalobacter formigenes in inflammatory bowel disease: possible role in renal stone formation
    Ritu Kumar
    Department of Urology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 19:1403-9. 2004
    ..The aim of the present study was to examine: (i) the colonization of O. formigenes in patients with IBD and controls and to correlate its presence with urinary oxalate excretion; and (ii) urinary analytes contributing to RS in IBD...