Research Topics
Species | Aleyamma MathewSummaryAffiliation: Regional Cancer Centre Country: India Publications
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Detail Information
Publications
Multi-center feasibility study evaluating recruitment, variability in risk factors and biomarkers for a diet and cancer cohort in IndiaRashmi Sinha
National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
BMC Public Health 11:405. 2011..The aim of this feasibility study was to evaluate whether a diet-focused cohort study of cancer could be established in India, providing insight into potentially unique diet and lifestyle exposures...
Trends in incidence and mortality rates of squamous cell carcinoma and adenocarcinoma of cervix--worldwideAleyamma Mathew
Regional Cancer Center, Trivandrum, Kerala, India
Asian Pac J Cancer Prev 10:645-50. 2009..In conclusion, cytology screening in combination with HPV screening for high-risk HPV types may maximize the possibilities of having early cervical lesions detected and treated...
Attributing death to cancer: cause-specific survival estimationA Mathew
Division of Epidemiology and Clinical Research, Regional Cancer Centre, Medical College P O, Trivandrum 695 011, India
J Postgrad Med 48:322-6. 2002..Rothman's confidence interval gives the most satisfactory result for survival estimate...
Assessment of follow-up, and the completeness and accuracy of cancer case ascertainment in three areas of IndiaAleyamma Mathew
Regional Cancer Center, Trivandrum, Kerala, India
Cancer Epidemiol 35:334-41. 2011..A prospective study of diet and cancer has not been conducted in India; consequently, little is known regarding follow-up rates or the completeness and accuracy of cancer case ascertainment...
Physical activity levels among urban and rural women in south India and the risk of breast cancer: a case-control studyAleyamma Mathew
Regional Cancer Center, Kerala, India
Eur J Cancer Prev 18:368-76. 2009..The proportion of BC avoided because of moderate or high PA was estimated to be 19% in urban women and 38% in rural women...
Fat, fiber, fruits, vegetables, and risk of colorectal adenomasAleyamma Mathew
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
Int J Cancer 108:287-92. 2004..Increased intake of dietary fiber was associated with a moderately decreased risk of adenomas...
Anthropometric factors and breast cancer risk among urban and rural women in South India: a multicentric case-control studyA Mathew
Regional Cancer Center, Trivandrum, India
Br J Cancer 99:207-13. 2008..05-1.69 for 25.0-29.9 kg/m(2) and OR=1.56, 95% CI: 1.03-2.35 for 30+ kg/m(2)) were associated with pre-menopausal BC risk. Our data support the hypotheses that increased anthropometric factors are risk factors of BC in India...
Meat intake and the recurrence of colorectal adenomasA Mathew
Nutritional Epidemiology Branch, Division of Epidemiologya nd Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Eur J Cancer Prev 13:159-64. 2004....
A cross-sectional investigation of regional patterns of diet and cardio-metabolic risk in IndiaCarrie R Daniel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
Nutr J 10:12. 2011..The role of diet in India's rapidly progressing chronic disease epidemic is unclear; moreover, diet may vary considerably across North-South regions...
Common genetic variants and central adiposity among Asian-IndiansSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
Obesity (Silver Spring) 20:1902-8. 2012....
Assessment of nicotine dependence among smokers in a selected rural population in Kerala, IndiaR Jayakrishnan
Regional Cancer Centre, Trivandrum, Kerala, India
Asian Pac J Cancer Prev 13:2663-7. 2012..An attempt was made to understand the nicotine dependence of smokers selected for an ongoing smoking cessation intervention programme in rural Kerala, India...
Measurement of spices and seasonings in India: opportunities for cancer epidemiology and preventionLeah M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Asian Pac J Cancer Prev 11:1621-9. 2010....
Cancer incidence rates among South Asians in four geographic regions: India, Singapore, UK and USTanuja Rastogi
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
Int J Epidemiol 37:147-60. 2008..Examining such rates may provide us with insights into future aetiological research possibilities as well as screening and prevention...
Obesity and kidney cancer risk in men: a meta-analysis (1992-2008)Grata Ildaphonse
Regional Cancer Center, Trivandrum, Kerala, India
Asian Pac J Cancer Prev 10:279-86. 2009..04-1.06) per unit increase in BMI based on the cohort studies. The present analysis confirmed the evidence of kidney cancer risk with increased BMI in men and obesity may be responsible at least in part for the rising incidence rates...
Assessment of confounding and interaction using the mantel-haenszel risk estimation methodSachin Jose
Regional Cancer Center, Trivandrum 695 011 Kerala, India
Asian Pac J Cancer Prev 9:323-5. 2008..In the present paper, assessment of the level of confounding and interaction between risk factors are illustrated using a case-control study of lung cancer conducted at the Regional Cancer Centre, Trivandrum...
A community based smoking cessation intervention trial for rural Kerala, IndiaR Jayakrishnan
Regional Cancer Centre, Trivandrum, Kerala, India
Asian Pac J Cancer Prev 12:3191-5. 2011..An attempt was made to compare tobacco prevalence and socioeconomic factors of two groups (intervention and control) from a selected rural community in Thiruvananthapuram, Kerala, India...
Comparison of quality of life between voice rehabilitated and nonrehabilitated laryngectomies in a developing world communityBipin Thomas Varghese
Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India
Acta Otolaryngol 131:310-5. 2011..Quality of life (QOL) scores were significantly higher among voice rehabilitated patients although this was accompanied by significant immediate and long-term morbidity and a cost implication for the patient...
The role of selective neck dissection (I-III) in the treatment of node negative (N0) neck in oral cancerElizabeth Mathew Iype
Department of Surgical Oncology, Regional Cancer Center, Medical College Campus, Trivandrum 695 003, Kerala, India
Oral Oncol 44:1134-8. 2008..It probably has a therapeutic role in the selected cases of squamous cell carcinoma of the oral cavity with N1 neck, and in these cases an extension of dissection to levels IV and V is beneficial...
Diet and stomach cancer: a case-control study in South IndiaA Mathew
Division of Epidemiology and Clinical Research, Regional Cancer Centre, Medical College PO, Trivandrum, Kerala, India
Eur J Cancer Prev 9:89-97. 2000..0-13.5) and consumption of high-temperature food (OR 7.0; 95% CI 3.7-12.9). On multivariate analysis, high consumption of rice, high consumption of chilli and consumption of high-temperature food were found to be independent risk factors...
Malignant tumours of the minor salivary glands: a survival analysis of 17 years from a tertiary referral cancer centreM Pandey
Department of Surgical Oncology, Regional Cancer Centre, Medical College P O Thiruvananthapuram 695 011, India
J Postgrad Med 49:25-8. 2003..Malignant tumours of the minor salivary glands are rare and constitute less than 0.5% of all malignant neoplasms...
Soft tissue sarcoma of the head and neck region in adultsM Pandey
Division of Surgical Oncology, Regional Cancer Centre, Medical College, Thiruvananthapuram, Kerala, 695 011, India
Int J Oral Maxillofac Surg 32:43-8. 2003..The overall survival rate for patients with soft tissue sarcoma of the head and neck is good, however, disease-free survival is poor as the majority of these fail within 2 years of completing treatment...
Obesity and kidney cancer risk in women: a meta-analysis (1992-2008)Aleyamma Mathew
Regional Cancer Center, Trivandrum, Kerala, India
Asian Pac J Cancer Prev 10:471-8. 2009..Increasing prevalence of obesity with higher proportion among women may be responsible for the rising incidence rates in women...
Treatment outcome in patients undergoing surgery for carcinoma larynx and hypopharynx: a follow-up studyBipin T Varghese
Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, India
Acta Otolaryngol 129:1480-5. 2009..Hypopharyngeal cancers therefore warrant a closer follow-up after an organ preservation protocol, to detect recurrence at the earliest stage and plan for an effective salvage surgery...
Cancer pain intensity measurements in outpatients: preferences and comparison of pain scales among patients, caregivers, physicians and nurses in southern IndiaRachel C Koshy
Regional Cancer Centre, Trivandrum, Kerala, 695 011, India
J Pain Palliat Care Pharmacother 18:5-13. 2004..Proxy reports were found to equally representative of patient's pain. VAS was the preferred pain assessment tool. In the absence of VAS scale, VDS also could be used. Proxy reports could be relied upon for management of pain...
Urinary bladder cancer risk among motor vehicle drivers: a meta-analysis of the evidence, 1977-2008L Manju
Regional Cancer Center, Trivandrum, Kerala, India
Asian Pac J Cancer Prev 10:287-94. 2009..The aim of the study was to summarize bladder cancer risk in motor vehicle drivers and railroad workers using meta-analysis techniques...
Squamous cell cancer of the buccal mucosa in young adultsE Mathew Iype
Division of Surgical Oncology, Regional Cancer Centre, Medical College P.O, Trivandrum 695011, Kerala, India
Br J Oral Maxillofac Surg 42:185-9. 2004..The 3 and 5 years disease-free survival were 72 and 61%, respectively. Non-smokers and patients with an advanced T stage at presentation had significantly worse prognoses...
Primary malignant mucosal melanoma of the head and neck region: pooled analysis of 60 published cases from India and review of literatureM Pandey
Department of Surgical Oncology, Regional Cencer Centre, Medical College PO, Trivandrum, Kerala, 695 011, India
Eur J Cancer Prev 11:3-10. 2002..Malignant mucosal melanoma has aggressive biological behaviour and poor outcome. Radical surgery and adjuvant radiotherapy may provide a better local control and may help in improving survival...
Primary sarcoma of the breastManoj Pandey
Division of Surgical Oncology, Regional Cancer Centre, Medical College, Trivandrum, Kerala, India
J Surg Oncol 87:121-5. 2004..Primary sarcoma occurring in breast is rare and comprises 0.5-1% of all breast neoplasm. Majority of the series include both stromal and cystosarcoma phyllodes, only a few hundred cases of sarcomas other then cystosarcoma are reported...
Secondary cytoreduction in epithelial ovarian cancer recurrence: a perspective from a regional cancer center in IndiaPrabhakaran Nair Rema
Division of Surgical Oncology, Regional Cancer Centre, Medical College Campus, Thiruvanandapuram, Kerala, India
J Reprod Med 54:506-10. 2009..To assess the impact of secondary cytoreduction on survival in our patients with recurrent epithelial ovarian cancer...
Oral cancer among patients under the age of 35 yearsE M Iype
Department of Surgical Oncology, Epidemiology and Clinical studies, Community Oncology and Radiation Oncology, Regional Cancer Centre, Medical College, Thiruvananthapuram 695 011, India
J Postgrad Med 47:171-6. 2001..Cancer of the oral cavity is one of the commonest cancers among males...
Cadherins as predictive markers of nodal metastasis in breast cancerM Madhavan
Division of Cancer Research, Regional Cancer Centre, Trivandrum, Kerala, India
Mod Pathol 14:423-7. 2001..5873), which requires further evaluation for confirmation of a common regulatory pathway that could be activated in the early onset of nodal metastasis...
Survival analysis: caveats and pitfallsA Mathew
Division of Epidemiology and Clinical Research, Regional Cancer Centre, Trivandrum, Kerala, India
Ann Chir Gynaecol 88:336-44. 1999..The problem is compounded in papers from third-world countries where bio-statisticians may not be available in all institutions to guide clinicians as to the selection of proper techniques...
Primary malignant melanoma of the mucous membranesM Pandey
Department of Surgical Oncology, Regional Cancer Centre, Kerala, India
Eur J Surg Oncol 24:303-7. 1998..To investigate malignant mucosal melanoma (MMM), a rare disease and one which has, till lately, remained unrecognized. Incidence of MMM ranges from 2 to 10% in various series...
Malignant phyllodes tumorM Pandey
Division of Surgical Oncology, Regional Cancer Center, Medical College PO, Thiruvananthapuram, Kerala, India
Breast J 7:411-6. 2001..7) showed a decreased hazards. Cystosarcoma phyllodes is a rare malignancy of the female breast. Surgery with adequate margins is the primary treatment. Adjuvant radiotherapy appears to improve the disease-free survival...
Squamous cell carcinoma of the tongue among young Indian adultsE Mathew Iype
Division of Surgical Oncology, Regional Cancer Centre, Trivandrum, Kerala, 695001 India
Neoplasia 3:273-7. 2001..Results of the present study suggest that contrary to the belief, the survival among young patients is almost similar to that in older patients...
Cancer vaccines: a step towards prevention and treatment of cancerM Pandey
Department of Surgical Oncology, Regional Cancer Centre, Medical College P O, Trivandrum, Kerala, India
Eur J Surg Oncol 25:209-14. 1999..This novel concept may help scientist to overcome the immunological tolerance and anti-tumour ineffectiveness induced by many human cancer cells and may lead to generation of tumour-specific vaccines...
Primary intraosseous carcinoma of the jaw: pooled analysis of world literature and report of two new casesG Thomas
Division of Community Oncology, Regional Cancer Centre, Trivandrum, Kerala, India
Int J Oral Maxillofac Surg 30:349-55. 2001..The tumour is locally aggressive and metastasizes to regional nodes. The overall and disease free survival is poor with almost 50% patients failing loco-regionally within the first 2 years of follow-up...
Childhood and adolescent meningiomas: a report of 38 cases and review of literatureG Menon
Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, 695011, India
Acta Neurochir (Wien) 151:239-44; discussion 244. 2009..The aim is to study the clinical, radiological and pathological features of childhood and adolescent meningiomas and analyse outcome prognosticators...
Primary malignant melanoma of the upper aero-digestive tractM Pandey
Department of Surgical Oncology, Regional Cancer Centre, Medical College PO, Thiruvananthapuram, Kerala, India
Int J Oral Maxillofac Surg 28:45-9. 1999..One patient was lost to follow-up. We suggest that data from various centres be pooled together in order to carry out a meta-analysis to address the question of optimal treatment for malignant melanoma of the upper aero-digestive tract...
Global increases in kidney cancer incidence, 1973-1992A Mathew
Division of Cancer Epidemiology and Clinical Research, Regional Cancer Center, Medical College, Trivandrum, 695 011, Kerala, India
Eur J Cancer Prev 11:171-8. 2002..Incidence trends for renal parenchyma cancer tracked those for total kidney cancers, and appeared to result from increases in the prevalence of risk factors and in use of diagnostic imaging procedures...
Independent and combined effects of tobacco smoking, chewing and alcohol drinking on the risk of oral, pharyngeal and esophageal cancers in Indian menAriana Znaor
Unit of Environmental Cancer Epidemiology, International Agency for Research on Cancer, 150 cours Albert-Thomas, 69372 Lyon Cedex 08, France
Int J Cancer 105:681-6. 2003..41 (95% CI 1.46-7.99). Furthermore, significant decreases in risks for all 3 cancer sites were observed in subjects who quit smoking even among those who had quit smoking 2-4 years before the interview...
Tobacco smoking and chewing, alcohol drinking and lung cancer risk among men in southern IndiaVendhan Gajalakshmi
Epidemiological Research Center, Chennai, India
Int J Cancer 107:441-7. 2003..67, 95%CI=1.02-7.02). Bidi smoking seems to have a stronger carcinogenic effect than cigarette smoking: this difference holds no matter which aspect of smoking was considered...
