Research Topics
| K DhawanSummaryAffiliation: Postgraduate Institute of Medical Education and Research Country: India Publications
| Collaborators |
Detail Information
Publications
Aphrodisiac activity of methanol extract of leaves of Passiflora incarnata Linn in miceKamaldeep Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences Panjab University, Chandigarh-160014, India
Phytother Res 17:401-3. 2003..e. 75, 100 and 150 mg/kg. Amongst these, the highest activity was observed with the 100 mg/kg dose when the mountings were calculated about 95 min after the administration of the test extracts...
Passiflora: a review updateKamaldeep Dhawan
Department of Drugs Control Administration, Government of Haryana State, Sector 6, Panchkula 134109, India
J Ethnopharmacol 94:1-23. 2004....
Restoration of chronic-Delta 9-THC-induced decline in sexuality in male rats by a novel benzoflavone moiety from Passiflora incarnata LinnKamaldeep Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
Br J Pharmacol 138:117-20. 2003..4 Upon discontinuation of THC, treatment with BZF (10 and 20 mg kg(-1) p.o.) also facilitated the early restoration chronic-THC-induced decline in libido, sperm count and sexual fertility within 7 days...
Attenuation of benzodiazepine dependence in mice by a tri-substituted benzoflavone moiety of Passiflora incarnata Linneaus: a non-habit forming anxiolyticKamaldeep Dhawan
Department of Drugs Control, Government of Haryana, Panchkula, India
J Pharm Pharm Sci 6:215-22. 2003....
Prevention of chronic alcohol and nicotine-induced azospermia, sterility and decreased libido, by a novel tri-substituted benzoflavone moiety from Passiflora incarnata Linneaus in healthy male ratsKamaldeep Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, 160014, Chandigarh, India
Life Sci 71:3059-69. 2002..BZF, the strongest inhibitor of aromatase enzyme, when administered concurrently with substances like alcohol and nicotine restores sexual virility, libido and vigour in male rats by maintaining the blood-testosterone levels to be high...
Antitussive activity of the methanol extract of Passiflora incarnata leavesKamaldeep Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, 160014, Chandigarh, India
Fitoterapia 73:397-9. 2002..o.) exhibited significant antitussive activity on sulfur dioxide-induced cough in mice, the cough inhibition (39.4 and 65.0%, respectively) being comparable to that of codeine phosphate (10 and 20 mg/kg, p.o., respectively)...
Comparative anxiolytic activity profile of various preparations of Passiflora incarnata linneaus: a comment on medicinal plants' standardizationKamaldeep Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
J Altern Complement Med 8:283-91. 2002..incarnata (standard) for their anxiolytic activity in mice using the elevated plus-maze model of anxiety...
Nicotine reversal effects of the benzoflavone moiety from Passiflora incarnata Linneaus in miceKamaldeep Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160 014, India
Addict Biol 7:435-41. 2002..These studies, although preliminary, suggest that the BZF may have value in treating nicotine addiction...
Drug/substance reversal effects of a novel tri-substituted benzoflavone moiety (BZF) isolated from Passiflora incarnata Linn.--a brief perspectiveKamaldeep Dhawan
University Institute of Pharmaceutical Sciences, Panjab Univesity, Chandigarh, India
Addict Biol 8:379-86. 2003....
Anxiolytic activity of aerial and underground parts of Passiflora incarnataK Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences Panjab University, Chandigarh 160014, India
Fitoterapia 72:922-6. 2001..incarnata act as natural adulterants by causing a significant increase in the anxiolytic dose. Therefore, separation of these parts is recommended prior to any pharmacological, phytochemical and standardization studies on P. incarnata...
Nifedipine loaded chitosan microspheres prepared by emulsification phase-separationS Dhawan
University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India 160014
Biotech Histochem 78:243-54. 2003..As the polymer content increased in the microspheres, the value of n (diffusional exponent characteristic of the release mechanism) approached one, which is indicative of zero order...
Antiasthmatic activity of the methanol extract of leaves of Passiflora incarnataKamaldeep Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
Phytother Res 17:821-2. 2003..e. 200 mg/kg, the preventive effects against Ach-chloride-induced-dyspnoea were also reduced. This may be due to defective alpha-adrenoceptor function reported after excessive or continuous administration of an alpha-receptor agonist...
Comparative biological activity study on Passiflora incarnata and P. edulisK Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
Fitoterapia 72:698-702. 2001..The methanol extract of P. incarnata exhibited significant anxiolytic activity at an oral dose of 125 mg/kg, whereas P. edulis was devoid of any significant activity...
Anti-anxiety studies on extracts of Passiflora incarnata LinneausK Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, 160014, Chandigarh, India
J Ethnopharmacol 78:165-70. 2001..The possibility of a phytoconstituent having benzoflavone nucleus as the basic moiety being responsible for the bioactivity of P. incarnata is highly anticipated...
Reversal of cannabinoids (delta9-THC) by the benzoflavone moiety from methanol extract of Passiflora incarnata Linneaus in mice: a possible therapy for cannabinoid addictionKamaldeep Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
J Pharm Pharmacol 54:875-81. 2002..Even an acute administration of the benzoflavone moiety (20 mg kg(-1), p.o.) significantly blocked the expression of withdrawal effects in delta9-THC-dependent mice...
Suppression of alcohol-cessation-oriented hyper-anxiety by the benzoflavone moiety of Passiflora incarnata Linneaus in miceKamaldeep Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
J Ethnopharmacol 81:239-44. 2002..incarnata. The chronic administration of P. incarnata with alcohol had better preventive effects than the single acute treatment with P. incarnata in alcohol-dependent mice...
Beneficial effects of chrysin and benzoflavone on virility in 2-year-old male ratsKamaldeep Dhawan
Pharmacognosy Division, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh-160014, India
J Med Food 5:43-8. 2002..Plant flavonoids have great potential for clinical and therapeutic applications against the physiological and biochemical effects of aging...
