Research Topics
Species | Bhushan PatwardhanSummaryCountry: India Publications
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Publications
Genetic polymorphism of CYP2C19 in Maharashtrian populationYogita Ghodke
Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune, 411007, Maharashtra, India
Eur J Epidemiol 22:907-15. 2007..Meta-analysis revealed that the study population is distinct from Caucasians, Africans and some of the Asian populations and significant heterogeneity exists among Indian subpopulations...- The assessment of osteoporosis risk factors in Iranian women compared with Indian womenAfsaneh Keramat
Shahroud University of Medical Sciences, Hafte Tir Avenue, Shahroud, Iran
BMC Musculoskelet Disord 9:28. 2008..In this study we aimed to assess the risk factors for osteoporosis in postmenopausal women from selected BMD centers of two developing Asian countries (Iran and India)... - Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward?Bhushan Patwardhan
Interdisciplinary School of Health Sciences, University of Pune, Pune 411 007, India
Drug Discov Today 14:804-11. 2009.... - Ethnopharmacology and drug discoveryBhushan Patwardhan
Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
J Ethnopharmacol 100:50-2. 2005..The ethnopharmacology knowledge, its holistic and systems approach supported by experiential base can serve as an innovative and powerful discovery engine for newer, safer and affordable medicines... - Classification of human population based on HLA gene polymorphism and the concept of Prakriti in AyurvedaPatwardhan Bhushan
Interdisciplinary School of Health Sciences, University of Pune, Pune, India
J Altern Complement Med 11:349-53. 2005..This means that current approaches for identifying phenotypes associated with haplotypes may be inadequate... - Botanical immunodrugs: scope and opportunitiesBhushan Patwardhan
Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
Drug Discov Today 10:495-502. 2005..Here, the importance of traditional medicine in natural product drug discovery related to immunodrugs is reviewed... - Natural products drug discovery: accelerating the clinical candidate development using reverse pharmacology approachesBhushan Patwardhan
Interdisciplinary School of Health Sciences, University of Pune, Pune 411 007, India
Indian J Exp Biol 48:220-7. 2010..Relevant case studies from India and other countries where such approaches have expedited the drug discovery and development process by reducing time and economizing investments with better safety are discussed... - Ayurvedic genomics: establishing a genetic basis for mind-body typologiesBhushan Patwardhan
University of Pune, Interdisciplinary School of Health Sciences, Pune, India
J Altern Complement Med 14:571-6. 2008..Accordingly, new horizons have opened for collaborative East-East research and for an individualized approach to disease management and activation of the full range of human potential, as articulated in Ayurveda and TCM... - Immunomodulatory activity of Asparagus racemosus on systemic Th1/Th2 immunity: implications for immunoadjuvant potentialManish Gautam
Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, Maharashtra, India
J Ethnopharmacol 121:241-7. 2009..Various studies have indicated immunomodulatory properties of Shatavari root extracts and formulations... - Physicochemical stability and biological activity of Withania somnifera extract under real-time and accelerated storage conditionsDada Patil
Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune, India
Planta Med 76:481-8. 2010..Thus, adequate control of temperature and humidity is important for WSE containing formulations. This study may help in proposing suitable guidance for storage conditions and shelf life of ashwagandha formulations... - Comparable efficacy of standardized Ayurveda formulation and hydroxychloroquine sulfate (HCQS) in the treatment of rheumatoid arthritis (RA): a randomized investigator-blind controlled studyArvind Chopra
Centre for Rheumatic Diseases CRD, 1988 Convent Street, Hermes Elegance, CAMP, Pune, 411001, India
Clin Rheumatol 31:259-69. 2012..This preliminary drug trial controlled for HCQS demonstrated a standardized Ayurvedic polyherb drug to be effective and safe in controlling active RA. A better-designed study with a longer evaluation period is recommended... - Evaluating higher doses of Shunthi - Guduchi formulations for safety in treatment of osteoarthritis knees: A Government of India NMITLI arthritis projectArvind Chopra
Centre for Rheumatic Diseases, Pune, Maharashtra, India
J Ayurveda Integr Med 3:38-44. 2012..This paper reports safety of these formulations when used in higher doses (1.5-2 times) along with Sallaki Guggul and Bhallataka Parpati (a Semecarpus anacardium preparation)... - Immunoadjuvant potential of Asparagus racemosus aqueous extract in experimental systemManish Gautam
Interdisciplinary School of Health Sciences, University of Pune, Pune, Maharastra 411007, India
J Ethnopharmacol 91:251-5. 2004..pertussis indicating development of protective immune response. Present study indicates applications of test material as potential immunoadjuvant that also offers direct therapeutic benefits resulting in less morbidity and mortality... - Profiling single nucleotide polymorphisms (SNPs) across intracellular folate metabolic pathway in healthy IndiansYogita Ghodke
Interdisciplinary School of Health Sciences, University of Pune, Pune, India
Indian J Med Res 133:274-9. 2011..These SNPs may be subjected to racial and ethnic differences. We carried out a study to determine the allelic frequencies of these SNPs in an Indian ethnic population... - Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?Yogita Ghodke
Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
Clin Rheumatol 27:787-9. 2008..Although a small sample study, our findings do not suggest a significant association of MTHFR/TS allele/genotype with MTX response in our ethnically distinct Indian (Asian) RA patients... - Traditional Medicine to Modern Pharmacogenomics: Ayurveda Prakriti Type and CYP2C19 Gene Polymorphism Associated with the Metabolic VariabilityYogita Ghodke
Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, India
Evid Based Complement Alternat Med 2011:249528. 2011..These observations are likely to have significant impact on phenotype-genotype correlation, drug discovery, pharmacogenomics and personalized medicine... - High-performance liquid chromatographic fingerprint for quality control of Terminalia arjuna containing Ayurvedic churna formulationSohan S Chitlange
Dr D Y Patil Institute of Pharmaceutical Science and Research, Pimpri, Pune, Maharashtra, India
J AOAC Int 92:1016-20. 2009.... - Immunoprotection by botanical drugs in cancer chemotherapySham Diwanay
Department of Microbiology, Abasaheb Garware College, Pune, India
J Ethnopharmacol 90:49-55. 2004..Treatment with these candidate drugs will be important in development of supportive treatment with cancer chemotherapy... - Chondroprotective Potential of Fruit Extracts of Phyllanthus emblica in OsteoarthritisVenil N Sumantran
Interactive Research School for Health Affairs IRSHA, Bhartiya Vidyapeeth Deemed University Medical College Campus, Dhankawadi, Pune 411043, Director, Interdisciplinary School of Health Sciences, Pune University, Pune 411007 and Director, Center for Rheumatic Diseases, CAMP, Pune 411001, India
Evid Based Complement Alternat Med 5:329-35. 2008..emblica fruits. These data provide pilot pre-clinical evidence for the use of P. emblica fruits as a chondroprotective agent in osteoarthritis therapy... - Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD)Kalpana Joshi
Interdisciplinary School of Health Sciences, University of Pune, Ganeshkhind, Pune 411007, Maharashtra, India
Prostaglandins Leukot Essent Fatty Acids 74:17-21. 2006..There was significant improvement in the symptoms of ADHD reflected by reduction in total hyperactivity scores of ADHD children derived from ADHD rating scale... - Development of SCAR (sequence-characterized amplified region) markers as a complementary tool for identification of ginger (Zingiber officinale Roscoe) from crude drugs and multicomponent formulationsPreeti Chavan
Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
Biotechnol Appl Biochem 50:61-9. 2008..One of the markers, P3, was found to be specific for Z. officinale and was successfully applied for detection of Z. officinale from Trikatu, a multicomponent formulation... - Cassia auriculata: Aspects of Safety Pharmacology and Drug InteractionAmrutesh S Puranik
Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
Evid Based Complement Alternat Med 2011:915240. 2011..Our results indicate the need to include pharmacokinetic herb-drug interaction studies as evidence for safety especially for technology-based extracts... - Cytoprotection and immunomodulation in cancer therapySham Diwanay
Department of Microbiology, Abasaheb Garware College, Pune - 411004, India
Curr Med Chem Anticancer Agents 4:479-90. 2004..This article describes chemical agents presently employed in clinical practice and reviews ethnopharmacological agents reported to have chemoprotective, radioprotective, immunomodulating, adaptogenic and antitumour activities...