Bhushan Patwardhan

Summary

Country: India

Publications

  1. ncbi request reprint Genetic polymorphism of CYP2C19 in Maharashtrian population
    Yogita Ghodke
    Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune, 411007, Maharashtra, India
    Eur J Epidemiol 22:907-15. 2007
  2. doi request reprint Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward?
    Bhushan Patwardhan
    Interdisciplinary School of Health Sciences, University of Pune, Pune 411 007, India
    Drug Discov Today 14:804-11. 2009
  3. pmc Cassia auriculata: Aspects of Safety Pharmacology and Drug Interaction
    Amrutesh S Puranik
    Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
    Evid Based Complement Alternat Med 2011:915240. 2011
  4. pmc The assessment of osteoporosis risk factors in Iranian women compared with Indian women
    Afsaneh Keramat
    Shahroud University of Medical Sciences, Hafte Tir Avenue, Shahroud, Iran
    BMC Musculoskelet Disord 9:28. 2008
  5. ncbi request reprint Ethnopharmacology and drug discovery
    Bhushan Patwardhan
    Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
    J Ethnopharmacol 100:50-2. 2005
  6. ncbi request reprint Classification of human population based on HLA gene polymorphism and the concept of Prakriti in Ayurveda
    Patwardhan Bhushan
    Interdisciplinary School of Health Sciences, University of Pune, Pune, India
    J Altern Complement Med 11:349-53. 2005
  7. ncbi request reprint Botanical immunodrugs: scope and opportunities
    Bhushan Patwardhan
    Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
    Drug Discov Today 10:495-502. 2005
  8. ncbi request reprint Natural products drug discovery: accelerating the clinical candidate development using reverse pharmacology approaches
    Bhushan Patwardhan
    Interdisciplinary School of Health Sciences, University of Pune, Pune 411 007, India
    Indian J Exp Biol 48:220-7. 2010
  9. doi request reprint Ayurvedic genomics: establishing a genetic basis for mind-body typologies
    Bhushan Patwardhan
    University of Pune, Interdisciplinary School of Health Sciences, Pune, India
    J Altern Complement Med 14:571-6. 2008
  10. doi request reprint Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial
    Arvind Chopra
    Center for Rheumatic Diseases, 1988 Convent Street, CAMP, Pune, India
    Rheumatology (Oxford) 52:1408-17. 2013

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Genetic polymorphism of CYP2C19 in Maharashtrian population
    Yogita Ghodke
    Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune, 411007, Maharashtra, India
    Eur J Epidemiol 22:907-15. 2007
    ..Meta-analysis revealed that the study population is distinct from Caucasians, Africans and some of the Asian populations and significant heterogeneity exists among Indian subpopulations...
  2. doi request reprint Traditional medicine-inspired approaches to drug discovery: can Ayurveda show the way forward?
    Bhushan Patwardhan
    Interdisciplinary School of Health Sciences, University of Pune, Pune 411 007, India
    Drug Discov Today 14:804-11. 2009
    ....
  3. pmc Cassia auriculata: Aspects of Safety Pharmacology and Drug Interaction
    Amrutesh S Puranik
    Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
    Evid Based Complement Alternat Med 2011:915240. 2011
    ..Our results indicate the need to include pharmacokinetic herb-drug interaction studies as evidence for safety especially for technology-based extracts...
  4. pmc The assessment of osteoporosis risk factors in Iranian women compared with Indian women
    Afsaneh Keramat
    Shahroud University of Medical Sciences, Hafte Tir Avenue, Shahroud, Iran
    BMC Musculoskelet Disord 9:28. 2008
    ..In this study we aimed to assess the risk factors for osteoporosis in postmenopausal women from selected BMD centers of two developing Asian countries (Iran and India)...
  5. ncbi request reprint Ethnopharmacology and drug discovery
    Bhushan Patwardhan
    Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
    J Ethnopharmacol 100:50-2. 2005
    ..The ethnopharmacology knowledge, its holistic and systems approach supported by experiential base can serve as an innovative and powerful discovery engine for newer, safer and affordable medicines...
  6. ncbi request reprint Classification of human population based on HLA gene polymorphism and the concept of Prakriti in Ayurveda
    Patwardhan Bhushan
    Interdisciplinary School of Health Sciences, University of Pune, Pune, India
    J Altern Complement Med 11:349-53. 2005
    ..This means that current approaches for identifying phenotypes associated with haplotypes may be inadequate...
  7. ncbi request reprint Botanical immunodrugs: scope and opportunities
    Bhushan Patwardhan
    Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
    Drug Discov Today 10:495-502. 2005
    ..Here, the importance of traditional medicine in natural product drug discovery related to immunodrugs is reviewed...
  8. ncbi request reprint Natural products drug discovery: accelerating the clinical candidate development using reverse pharmacology approaches
    Bhushan Patwardhan
    Interdisciplinary School of Health Sciences, University of Pune, Pune 411 007, India
    Indian J Exp Biol 48:220-7. 2010
    ..Relevant case studies from India and other countries where such approaches have expedited the drug discovery and development process by reducing time and economizing investments with better safety are discussed...
  9. doi request reprint Ayurvedic genomics: establishing a genetic basis for mind-body typologies
    Bhushan Patwardhan
    University of Pune, Interdisciplinary School of Health Sciences, Pune, India
    J Altern Complement Med 14:571-6. 2008
    ..Subsequently, Chen et al. (2007) reported a similar study in this journal using a classification based on Traditional Chinese Medicine (TCM) theory...
  10. doi request reprint Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial
    Arvind Chopra
    Center for Rheumatic Diseases, 1988 Convent Street, CAMP, Pune, India
    Rheumatology (Oxford) 52:1408-17. 2013
    ..To demonstrate clinical equivalence between two standardized Ayurveda (India) formulations (SGCG and SGC), glucosamine and celecoxib (NSAID)...
  11. doi request reprint Immunomodulatory activity of Asparagus racemosus on systemic Th1/Th2 immunity: implications for immunoadjuvant potential
    Manish Gautam
    Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, Maharashtra, India
    J Ethnopharmacol 121:241-7. 2009
    ..Various studies have indicated immunomodulatory properties of Shatavari root extracts and formulations...
  12. doi request reprint Physicochemical stability and biological activity of Withania somnifera extract under real-time and accelerated storage conditions
    Dada Patil
    Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune, India
    Planta Med 76:481-8. 2010
    ..Thus, adequate control of temperature and humidity is important for WSE containing formulations. This study may help in proposing suitable guidance for storage conditions and shelf life of ashwagandha formulations...
  13. doi request reprint Comparable efficacy of standardized Ayurveda formulation and hydroxychloroquine sulfate (HCQS) in the treatment of rheumatoid arthritis (RA): a randomized investigator-blind controlled study
    Arvind Chopra
    Centre for Rheumatic Diseases CRD, 1988 Convent Street, Hermes Elegance, CAMP, Pune, 411001, India
    Clin Rheumatol 31:259-69. 2012
    ..This preliminary drug trial controlled for HCQS demonstrated a standardized Ayurvedic polyherb drug to be effective and safe in controlling active RA. A better-designed study with a longer evaluation period is recommended...
  14. pmc Evaluating higher doses of Shunthi - Guduchi formulations for safety in treatment of osteoarthritis knees: A Government of India NMITLI arthritis project
    Arvind Chopra
    Centre for Rheumatic Diseases, Pune, Maharashtra, India
    J Ayurveda Integr Med 3:38-44. 2012
    ..This paper reports safety of these formulations when used in higher doses (1.5-2 times) along with Sallaki Guggul and Bhallataka Parpati (a Semecarpus anacardium preparation)...
  15. pmc Profiling single nucleotide polymorphisms (SNPs) across intracellular folate metabolic pathway in healthy Indians
    Yogita Ghodke
    Interdisciplinary School of Health Sciences, University of Pune, Pune, India
    Indian J Med Res 133:274-9. 2011
    ..These SNPs may be subjected to racial and ethnic differences. We carried out a study to determine the allelic frequencies of these SNPs in an Indian ethnic population...
  16. ncbi request reprint Immunoadjuvant potential of Asparagus racemosus aqueous extract in experimental system
    Manish Gautam
    Interdisciplinary School of Health Sciences, University of Pune, Pune, Maharastra 411007, India
    J Ethnopharmacol 91:251-5. 2004
    ..pertussis indicating development of protective immune response. Present study indicates applications of test material as potential immunoadjuvant that also offers direct therapeutic benefits resulting in less morbidity and mortality...
  17. doi request reprint Effect of botanical immunomodulators on human CYP3A4 inhibition: implications for concurrent use as adjuvants in cancer therapy
    Dada Patil
    Serum Institute of India Research Foundation, Hadapsar, Pune, India
    Integr Cancer Ther 13:167-75. 2014
    ....
  18. doi request reprint Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?
    Yogita Ghodke
    Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
    Clin Rheumatol 27:787-9. 2008
    ..Although a small sample study, our findings do not suggest a significant association of MTHFR/TS allele/genotype with MTX response in our ethnically distinct Indian (Asian) RA patients...
  19. pmc Traditional Medicine to Modern Pharmacogenomics: Ayurveda Prakriti Type and CYP2C19 Gene Polymorphism Associated with the Metabolic Variability
    Yogita Ghodke
    Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, India
    Evid Based Complement Alternat Med 2011:249528. 2011
    ..These observations are likely to have significant impact on phenotype-genotype correlation, drug discovery, pharmacogenomics and personalized medicine...
  20. ncbi request reprint High-performance liquid chromatographic fingerprint for quality control of Terminalia arjuna containing Ayurvedic churna formulation
    Sohan S Chitlange
    Dr D Y Patil Institute of Pharmaceutical Science and Research, Pimpri, Pune, Maharashtra, India
    J AOAC Int 92:1016-20. 2009
    ....
  21. ncbi request reprint Immunoprotection by botanical drugs in cancer chemotherapy
    Sham Diwanay
    Department of Microbiology, Abasaheb Garware College, Pune, India
    J Ethnopharmacol 90:49-55. 2004
    ..Treatment with these candidate drugs will be important in development of supportive treatment with cancer chemotherapy...
  22. pmc Chondroprotective Potential of Fruit Extracts of Phyllanthus emblica in Osteoarthritis
    Venil N Sumantran
    Interactive Research School for Health Affairs IRSHA, Bhartiya Vidyapeeth Deemed University Medical College Campus, Dhankawadi, Pune 411043, Director, Interdisciplinary School of Health Sciences, Pune University, Pune 411007 and Director, Center for Rheumatic Diseases, CAMP, Pune 411001, India
    Evid Based Complement Alternat Med 5:329-35. 2008
    ..emblica fruits. These data provide pilot pre-clinical evidence for the use of P. emblica fruits as a chondroprotective agent in osteoarthritis therapy...
  23. ncbi request reprint Development of SCAR (sequence-characterized amplified region) markers as a complementary tool for identification of ginger (Zingiber officinale Roscoe) from crude drugs and multicomponent formulations
    Preeti Chavan
    Bioprospecting Laboratory, Interdisciplinary School of Health Sciences, University of Pune, Pune 411007, India
    Biotechnol Appl Biochem 50:61-9. 2008
    ..One of the markers, P3, was found to be specific for Z. officinale and was successfully applied for detection of Z. officinale from Trikatu, a multicomponent formulation...
  24. ncbi request reprint Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD)
    Kalpana Joshi
    Interdisciplinary School of Health Sciences, University of Pune, Ganeshkhind, Pune 411007, Maharashtra, India
    Prostaglandins Leukot Essent Fatty Acids 74:17-21. 2006
    ..There was significant improvement in the symptoms of ADHD reflected by reduction in total hyperactivity scores of ADHD children derived from ADHD rating scale...
  25. ncbi request reprint Cytoprotection and immunomodulation in cancer therapy
    Sham Diwanay
    Department of Microbiology, Abasaheb Garware College, Pune 411004, India
    Curr Med Chem Anticancer Agents 4:479-90. 2004
    ..This article describes chemical agents presently employed in clinical practice and reviews ethnopharmacological agents reported to have chemoprotective, radioprotective, immunomodulating, adaptogenic and antitumour activities...