Anjali Shiras

Summary

Affiliation: National Centre for Cell Science
Country: India

Publications

  1. ncbi A unique model system for tumor progression in GBM comprising two developed human neuro-epithelial cell lines with differential transforming potential and coexpressing neuronal and glial markers
    Anjali Shiras
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune, India
    Neoplasia 5:520-32. 2003
  2. ncbi Spontaneous transformation of human adult nontumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma
    Anjali Shiras
    National Centre for Cell Science NCCS, NCCS Complex, University of Pune Campus, Ganeshkhind, Pune 411007, Maharashtra, India
    Stem Cells 25:1478-89. 2007
  3. ncbi Independent activation of Akt and NF-kappaB pathways and their role in resistance to TNF-alpha mediated cytotoxicity in gliomas
    P Sudheerkumar
    National Centre for Cell Science NCCS, Ganeshkhind, Pune, India
    Mol Carcinog 47:126-36. 2008
  4. ncbi Differential expression and role of p21cip/waf1 and p27kip1 in TNF-alpha-induced inhibition of proliferation in human glioma cells
    Pabbisetty Sudheer Kumar
    National Centre for Cell Science, NCCS, Ganeshkhind, Pune, India
    Mol Cancer 6:42. 2007
  5. ncbi Dlxin-1, a MAGE family protein, induces accelerated neurite outgrowth and cell survival by enhanced and early activation of MEK and Akt signalling pathways in PC12 cells
    E Maheswara Reddy
    National Centre for Cell Science NCCS, NCCS Complex, University of Pune Campus, Ganeshkhind, Pune 411007, Maharashtra, India
    Exp Cell Res 316:2220-36. 2010
  6. ncbi Rictor regulates MMP-9 activity and invasion through Raf-1-MEK-ERK signaling pathway in glioma cells
    Gowry Das
    National Centre for Cell Science NCCS, Ganeshkhind, Pune, Maharashtra, India
    Mol Carcinog 50:412-23. 2011
  7. ncbi Cytotoxicity of sophorolipid-gellan gum-gold nanoparticle conjugates and their doxorubicin loaded derivatives towards human glioma and human glioma stem cell lines
    Sheetal Dhar
    Materials Chemistry Division, National Chemical Laboratory, Pune, 411 008, India
    Nanoscale 3:575-80. 2011
  8. ncbi Porphyran capped gold nanoparticles as a novel carrier for delivery of anticancer drug: in vitro cytotoxicity study
    Vinod Venkatpurwar
    Department of Pharmaceutics, Bharati Vidyapeeth University, Poona College of Pharmacy, Erandwane, Pune 411038, Maharashtra, India
    Int J Pharm 409:314-20. 2011
  9. ncbi Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas
    Ganeshkumar Rajendran
    National Centre for Cell Science NCCS, Pune, India
    J Neurooncol 104:483-94. 2011
  10. ncbi Differential expression of CD44(S) and variant isoforms v3, v10 in three-dimensional cultures of mouse melanoma cell lines
    Anjali Shiras
    National Centre for Cell Science NCCS, NCCS Complex, Ganeshkhind, Pune 411007, India
    Clin Exp Metastasis 19:445-55. 2002

Collaborators

  • Varsha Pokharkar
  • Navjot Kaur
  • Pabbisetty Sudheer Kumar
  • E Maheswara Reddy
  • Sheetal Dhar
  • Gowry Das
  • Padma Shastry
  • Kasturi Joshi-Navare
  • Asmita Prabhune
  • Vinod Venkatpurwar
  • Ganeshkumar Rajendran
  • Karthik Shanmuganandam
  • S Mruthyunjaya
  • B L V Prasad
  • P Sudheerkumar
  • Abhay Goel
  • Dattatraya Muzumdar
  • Ameya Bendre
  • Dattatreya Mujumdar
  • Rumma Manchanda
  • Radha Pujari
  • Sivarajan T Chettiar
  • Ravibhushan Godbole
  • Varsha Shepal
  • Jayashree C Jagtap
  • Vandna Prasad

Detail Information

Publications14

  1. ncbi A unique model system for tumor progression in GBM comprising two developed human neuro-epithelial cell lines with differential transforming potential and coexpressing neuronal and glial markers
    Anjali Shiras
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune, India
    Neoplasia 5:520-32. 2003
    ..This in vitro model system assumes importance in unraveling the cellular and molecular mechanisms in differentiation, transformation, and gliomagenesis...
  2. ncbi Spontaneous transformation of human adult nontumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma
    Anjali Shiras
    National Centre for Cell Science NCCS, NCCS Complex, University of Pune Campus, Ganeshkhind, Pune 411007, Maharashtra, India
    Stem Cells 25:1478-89. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  3. ncbi Independent activation of Akt and NF-kappaB pathways and their role in resistance to TNF-alpha mediated cytotoxicity in gliomas
    P Sudheerkumar
    National Centre for Cell Science NCCS, Ganeshkhind, Pune, India
    Mol Carcinog 47:126-36. 2008
    ..The findings thus underscore the relevance of spheroids as appropriate in vitro models for studying the signaling pathways in drug induced resistance...
  4. ncbi Differential expression and role of p21cip/waf1 and p27kip1 in TNF-alpha-induced inhibition of proliferation in human glioma cells
    Pabbisetty Sudheer Kumar
    National Centre for Cell Science, NCCS, Ganeshkhind, Pune, India
    Mol Cancer 6:42. 2007
    ..The study was done with human glioma cell lines -LN-18 and LN-229 cells, using monolayer cultures and Multicellular Spheroids (MCS) as in vitro models...
  5. ncbi Dlxin-1, a MAGE family protein, induces accelerated neurite outgrowth and cell survival by enhanced and early activation of MEK and Akt signalling pathways in PC12 cells
    E Maheswara Reddy
    National Centre for Cell Science NCCS, NCCS Complex, University of Pune Campus, Ganeshkhind, Pune 411007, Maharashtra, India
    Exp Cell Res 316:2220-36. 2010
    ....
  6. ncbi Rictor regulates MMP-9 activity and invasion through Raf-1-MEK-ERK signaling pathway in glioma cells
    Gowry Das
    National Centre for Cell Science NCCS, Ganeshkhind, Pune, Maharashtra, India
    Mol Carcinog 50:412-23. 2011
    ..Our findings identify a role for Rictor in bridging two major pathways-Akt (PKB)/mTOR and Raf-1-MEK-ERK in regulating MMP-9 activity and invasion of glioma tumor cells...
  7. ncbi Cytotoxicity of sophorolipid-gellan gum-gold nanoparticle conjugates and their doxorubicin loaded derivatives towards human glioma and human glioma stem cell lines
    Sheetal Dhar
    Materials Chemistry Division, National Chemical Laboratory, Pune, 411 008, India
    Nanoscale 3:575-80. 2011
    ..The cytotoxic effects became more prominent once the anti cancer drug doxorubicin hydrochloride was also conjugated to these gold nanoparticles...
  8. ncbi Porphyran capped gold nanoparticles as a novel carrier for delivery of anticancer drug: in vitro cytotoxicity study
    Vinod Venkatpurwar
    Department of Pharmaceutics, Bharati Vidyapeeth University, Poona College of Pharmacy, Erandwane, Pune 411038, Maharashtra, India
    Int J Pharm 409:314-20. 2011
    ..4). Further, the DOX loaded AuNps demonstrated higher cytotoxicity on LN-229 cell line as compared with an equal dose of native DOX solution. This established the potential of these AuNps as a carrier for anticancer drug delivery...
  9. ncbi Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas
    Ganeshkumar Rajendran
    National Centre for Cell Science NCCS, Pune, India
    J Neurooncol 104:483-94. 2011
    ....
  10. ncbi Differential expression of CD44(S) and variant isoforms v3, v10 in three-dimensional cultures of mouse melanoma cell lines
    Anjali Shiras
    National Centre for Cell Science NCCS, NCCS Complex, Ganeshkhind, Pune 411007, India
    Clin Exp Metastasis 19:445-55. 2002
    ....
  11. ncbi Wnt3a mediated activation of Wnt/β-catenin signaling promotes tumor progression in glioblastoma
    Navjot Kaur
    National Centre for Cell Science NCCS, NCCS Complex, University of Pune Campus, Ganeshkhind, Pune 411007, Maharashtra, India Electronic address
    Mol Cell Neurosci 54:44-57. 2013
    ....
  12. ncbi Laminin-1 induces neurite outgrowth in human mesenchymal stem cells in serum/differentiation factors-free conditions through activation of FAK-MEK/ERK signaling pathways
    S Mruthyunjaya
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Biochem Biophys Res Commun 391:43-8. 2010
    ..Our study demonstrates the involvement of integrin alpha6beta1 and FAK-MEK/ERK signaling pathways in laminin-1-induced neurite outgrowth in MSCs in the absence of serum and differentiation factors...
  13. ncbi Differentiation-inducing ability of sophorolipids of oleic and linoleic acids using a glioma cell line
    Kasturi Joshi-Navare
    Biochemical Sciences Division, National Chemical Laboratory, Pune, India
    Biotechnol J 6:509-12. 2011
    ..In this study we present the morphological evidence of the potential of sophorolipids as differentiation inducers...
  14. ncbi Natural gum reduced/stabilized gold nanoparticles for drug delivery formulations
    Sheetal Dhar
    Materials Chemistry Division, National Chemical Laboratory, Pune, India
    Chemistry 14:10244-50. 2008
    ..Subsequently these have been used to load anthracycline ring antibiotic doxorubicin hydrochloride. The drug loaded on these nanoparticles showed enhanced cytotoxic effects on human glioma cell lines LN-18 and LN-229...