Ipsita Roy

Summary

Affiliation: National Institute of Pharmaceutical Education and Research
Country: India

Publications

  1. ncbi request reprint Biomedical applications of polyhydroxyalkanoates: an overview of animal testing and in vivo responses
    Sabeel P Valappil
    Department of Molecular and Applied Biosciences, University of Westminster, 115 New Cavendish Street, London, UK
    Expert Rev Med Devices 3:853-68. 2006
  2. ncbi request reprint Therapeutic applications of aptamers
    Gurjot Kaur
    National Institute of Pharmaceutical Education and Research NIPER, Department of Biotechnology, Sector 67, SAS Nagar, Punjab 160 062, India
    Expert Opin Investig Drugs 17:43-60. 2008
  3. doi request reprint Coumarin 6 and 1,6-diphenyl-1,3,5-hexatriene (DPH) as fluorescent probes to monitor protein aggregation
    Pinakin K Makwana
    Department of Biotechnology, National Institute of Pharmaceutical Education and Research, S A S Nagar, Punjab, India
    Analyst 136:2161-7. 2011
  4. doi request reprint Design and development of antisense drugs
    Ravinder Malik
    National Institute of Pharmaceutical Education and Research NIPER, Department of Biotechnology, Sector 67, SAS Nagar, 160 062 Punjab, India 91 172 2214 682 91 172 2214 692
    Expert Opin Drug Discov 3:1189-207. 2008
  5. ncbi request reprint Making sense of therapeutics using antisense technology
    Ravinder Malik
    National Institute of Pharmaceutical Education and Research NIPER, Department of Biotechnology, Sector 67, S A S Nagar, Punjab 160 062, India
    Expert Opin Drug Discov 6:507-26. 2011
  6. pmc Effect of chemical chaperones in improving the solubility of recombinant proteins in Escherichia coli
    Shivcharan Prasad
    Department of Biotechnology, National Institute of Pharmaceutical Education and Research NIPER, Sector 67, S A S Nagar, Punjab 160 062, India
    Appl Environ Microbiol 77:4603-9. 2011
  7. ncbi request reprint Smart polymeric materials: emerging biochemical applications
    Ipsita Roy
    Chemistry Department, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi 11 00 16, India
    Chem Biol 10:1161-71. 2003
  8. ncbi request reprint Smart biocatalysts: design and applications
    Ipsita Roy
    Chemistry Department, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi 110016, India
    Adv Biochem Eng Biotechnol 86:159-89. 2004

Collaborators

  • Ravinder Malik
  • Pinakin K Makwana
  • Shivcharan Prasad
  • Gurjot Kaur
  • Sabeel P Valappil
  • Prashant B Khadatare
  • Prashant N Jethva
  • Aldo R Boccaccini
  • Superb K Misra

Detail Information

Publications8

  1. ncbi request reprint Biomedical applications of polyhydroxyalkanoates: an overview of animal testing and in vivo responses
    Sabeel P Valappil
    Department of Molecular and Applied Biosciences, University of Westminster, 115 New Cavendish Street, London, UK
    Expert Rev Med Devices 3:853-68. 2006
    ..This review summarizes the animal testing, tissue response, in vivo molecular stability and challenges of using PHAs for medical applications. In future, PHAs may become the materials of choice for various medical applications...
  2. ncbi request reprint Therapeutic applications of aptamers
    Gurjot Kaur
    National Institute of Pharmaceutical Education and Research NIPER, Department of Biotechnology, Sector 67, SAS Nagar, Punjab 160 062, India
    Expert Opin Investig Drugs 17:43-60. 2008
    ..Cases of other aptamers, which show promise as drugs, are discussed in slightly greater detail. Comparison with antibodies and small molecules, which have hitherto held monopoly in this area, is also made...
  3. doi request reprint Coumarin 6 and 1,6-diphenyl-1,3,5-hexatriene (DPH) as fluorescent probes to monitor protein aggregation
    Pinakin K Makwana
    Department of Biotechnology, National Institute of Pharmaceutical Education and Research, S A S Nagar, Punjab, India
    Analyst 136:2161-7. 2011
    ..Coumarin 6 can distinguish between both types of aggregates. It also exhibits the characteristic sigmoidal curve of amyloid formation, with higher sensitivity for detection of fibrillation than the conventionally used Thioflavin T...
  4. doi request reprint Design and development of antisense drugs
    Ravinder Malik
    National Institute of Pharmaceutical Education and Research NIPER, Department of Biotechnology, Sector 67, SAS Nagar, 160 062 Punjab, India 91 172 2214 682 91 172 2214 692
    Expert Opin Drug Discov 3:1189-207. 2008
    ..Conclusion: Although specificity and selectivity are the key features of antisense oligonucleotides, the need to target the right tissues and reach the nucleus remains a challenge to overcome...
  5. ncbi request reprint Making sense of therapeutics using antisense technology
    Ravinder Malik
    National Institute of Pharmaceutical Education and Research NIPER, Department of Biotechnology, Sector 67, S A S Nagar, Punjab 160 062, India
    Expert Opin Drug Discov 6:507-26. 2011
    ..The main problem lies in designing ASOs which are stable in in vivo milieu. The delivery and bioavailability of the oligonucleotide to the site of action continue to be hurdles in the development of ASOs and therapeutic molecules...
  6. pmc Effect of chemical chaperones in improving the solubility of recombinant proteins in Escherichia coli
    Shivcharan Prasad
    Department of Biotechnology, National Institute of Pharmaceutical Education and Research NIPER, Sector 67, S A S Nagar, Punjab 160 062, India
    Appl Environ Microbiol 77:4603-9. 2011
    ..Instead of forming inclusion bodies, HypF-N could be expressed as a soluble protein in the presence of sorbitol, arginine, and trehalose in the expression medium...
  7. ncbi request reprint Smart polymeric materials: emerging biochemical applications
    Ipsita Roy
    Chemistry Department, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi 11 00 16, India
    Chem Biol 10:1161-71. 2003
    ..The versatility and untapped potential of smart polymeric materials makes them one of the most exciting interfaces of chemistry and biology...
  8. ncbi request reprint Smart biocatalysts: design and applications
    Ipsita Roy
    Chemistry Department, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi 110016, India
    Adv Biochem Eng Biotechnol 86:159-89. 2004
    ..All the above applications involve hydrolysis and are hence carried out in aqueous media. For synthetic applications such as synthesis of peptides, some photoresponsive polymers linked to proteases have recently been described...