Sankar K Guchhait

Summary

Affiliation: National Institute of Pharmaceutical Education and Research
Country: India

Publications

  1. Guchhait S, Chaudhary V, Madaan C. A chemoselective Ugi-type reaction in water using TMSCN as a functional isonitrile equivalent: generation of heteroaromatic molecular diversity. Org Biomol Chem. 2012;10:9271-7 pubmed publisher
    ..This reaction coupling with cascade cyclization provides various privileged tetracyclic heteroaromatic scaffolds. ..
  2. Priyadarshani G, Amrutkar S, Nayak A, Banerjee U, Kundu C, Guchhait S. Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of topoisomerase II?. Eur J Med Chem. 2016;122:43-54 pubmed publisher
  3. Guchhait S, Saini M, Sumkaria D, Chaudhary V. A nitrile-stabilized ammonium ylide as a masked C-C[double bond, length as m-dash]N synthon in heterocyclization with amidine-imine: 3-component assembly to fused pyrimidine scaffolds. Chem Commun (Camb). 2017;53:6941-6944 pubmed publisher
    ..Its reaction with 2-aminopyridine-derived aldimine undergoes electronically-assisted nucleophilic additions and Hofmann elimination, and provides a new method to access fused pyrimidines. ..