Sanjeev Galande

Summary

Affiliation: National Centre for Cell Science
Country: India

Publications

  1. ncbi request reprint Chromatin (dis)organization and cancer: BUR-binding proteins as biomarkers for cancer
    Sanjeev Galande
    National Center for Cell Science, Ganeshkhind, Pune 411 007, India
    Curr Cancer Drug Targets 2:157-90. 2002
  2. ncbi request reprint The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1
    Sanjeev Galande
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Curr Opin Genet Dev 17:408-14. 2007
  3. ncbi request reprint Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo
    P Pavan Kumar
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Mol Cell 22:231-43. 2006
  4. pmc Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1
    Prabhat Kumar Purbey
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    Mol Cell Biol 29:1321-37. 2009
  5. pmc SATB1-binding sequences and Alu-like motifs define a unique chromatin context in the vicinity of human immunodeficiency virus type 1 integration sites
    Pavan P Kumar
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    J Virol 81:5617-27. 2007
  6. pmc PDZ domain-mediated dimerization and homeodomain-directed specificity are required for high-affinity DNA binding by SATB1
    Prabhat Kumar Purbey
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Nucleic Acids Res 36:2107-22. 2008
  7. pmc Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Pune, India
    PLoS Biol 8:e1000296. 2010
  8. ncbi request reprint Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus
    Pavan P Kumar
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Nat Cell Biol 9:45-56. 2007
  9. doi request reprint Phosphorylation-dependent regulation of SATB1, the higher-order chromatin organizer and global gene regulator
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Maharashtra, India
    Methods Mol Biol 647:317-35. 2010
  10. ncbi request reprint N-terminal PDZ-like domain of chromatin organizer SATB1 contributes towards its function as transcription regulator
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Pune 411 007, India
    J Biosci 36:461-9. 2011

Collaborators

  • Debashis Mitra
  • Samit Chattopadhyay
  • Henning Urlaub
  • Manoj Kumar Bhat
  • Jomon Joseph
  • Prabhat Kumar Purbey
  • Dimple Notani
  • P Pavan Kumar
  • Ranveer S Jayani
  • Pavan P Kumar
  • Amita S Limaye
  • Sameet Mehta
  • Amita Limaye
  • Kamalvishnu P Gottimukkala
  • Praveena L Ramanujam
  • Sunita Singh
  • Hemant J Purohit
  • Dyavar S Ravi
  • P Cyril Jayakumar
  • Milind S Patole
  • Sharmila Bapat
  • Shravanti Rampalli
  • Ruchika Kaul
  • Chandan Kumar-Sinha
  • Madhujit V Damle
  • Atya Kapley
  • Giridhar M Taori
  • Rajpal S Kashyap
  • K N Ganesh
  • Hatim F Daginawala
  • Dhananjay V Raje
  • Ramesh R Bhonde
  • Oliver Bischof
  • Anne Dejean
  • Chandan Kumar Sinha
  • P D Deepalakshmi
  • Asavari Kulkarni
  • Pavan Kumar
  • Sujoy Mukherjee
  • Farid Ahmed
  • Devraj Mogare
  • Rishiraj Chhipa

Detail Information

Publications18

  1. ncbi request reprint Chromatin (dis)organization and cancer: BUR-binding proteins as biomarkers for cancer
    Sanjeev Galande
    National Center for Cell Science, Ganeshkhind, Pune 411 007, India
    Curr Cancer Drug Targets 2:157-90. 2002
    ..Experimental strategies by which these proteins can be exploited as carcinoma-specific diagnostic markers and as targets for antineoplastic therapy are discussed...
  2. ncbi request reprint The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1
    Sanjeev Galande
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Curr Opin Genet Dev 17:408-14. 2007
    ..At genome-wide level, SATB1 seems to play a role in organization of the transcriptionally poised chromatin...
  3. ncbi request reprint Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo
    P Pavan Kumar
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Mol Cell 22:231-43. 2006
    ....
  4. pmc Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1
    Prabhat Kumar Purbey
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    Mol Cell Biol 29:1321-37. 2009
    ..Collectively, these results provide a mechanistic insight into the role of SATB1-CtBP1 interaction in the repression and derepression of SATB1 target genes during Wnt signaling in T cells...
  5. pmc SATB1-binding sequences and Alu-like motifs define a unique chromatin context in the vicinity of human immunodeficiency virus type 1 integration sites
    Pavan P Kumar
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    J Virol 81:5617-27. 2007
    ..We propose that definitive sequence features such as the Alu-like motifs and SATB1-binding sites provide a unique chromatin context in vivo which is preferentially targeted by the HIV-1 integration machinery...
  6. pmc PDZ domain-mediated dimerization and homeodomain-directed specificity are required for high-affinity DNA binding by SATB1
    Prabhat Kumar Purbey
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Nucleic Acids Res 36:2107-22. 2008
    ..These studies provide mechanistic insights into the mode of DNA binding and its effect on the regulation of transcription by SATB1...
  7. pmc Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Pune, India
    PLoS Biol 8:e1000296. 2010
    ....
  8. ncbi request reprint Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus
    Pavan P Kumar
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Nat Cell Biol 9:45-56. 2007
    ..Our studies identify PML and SATB1 as a regulatory complex that governs transcription by orchestrating dynamic chromatin-loop architecture...
  9. doi request reprint Phosphorylation-dependent regulation of SATB1, the higher-order chromatin organizer and global gene regulator
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Maharashtra, India
    Methods Mol Biol 647:317-35. 2010
    ..Finally, we describe a functional assay to monitor the effect of phosphorylation on transcription activity of SATB1 in vivo using MAR-linked reporter assay, in the presence and absence of PKC inhibitors...
  10. ncbi request reprint N-terminal PDZ-like domain of chromatin organizer SATB1 contributes towards its function as transcription regulator
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Pune 411 007, India
    J Biosci 36:461-9. 2011
    ..These studies clearly demonstrated the role of PDZ domain of SATB1 in global gene regulation presumably through its interaction with other cellular proteins...
  11. pmc Displacement of SATB1-bound histone deacetylase 1 corepressor by the human immunodeficiency virus type 1 transactivator induces expression of interleukin-2 and its receptor in T cells
    P Pavan Kumar
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    Mol Cell Biol 25:1620-33. 2005
    ..These results suggest a novel mechanism by which HIV-1 Tat might overcome SATB1-mediated repression in T cells...
  12. ncbi request reprint pC6-2/caspase-6 system to purify glutathione-S-transferase-free recombinant fusion proteins expressed in Escherichia coli
    Prabhat Kumar Purbey
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    Nat Protoc 1:1820-7. 2006
    ..Here, we describe the detailed protocol for purifying proteins using our pC6-2/caspase-6 expression and purification system. The cleavage by caspase-6 occurs in <30 min and the entire procedure can be completed in 2 d...
  13. doi request reprint Studying histone modifications and their genomic functions by employing chromatin immunoprecipitation and immunoblotting
    Ranveer S Jayani
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Methods Cell Biol 98:35-56. 2010
    ..We also describe the protocol for immunoblot analysis of histones using antibodies against key histone modifications. This chapter will serve as a useful resource in the study of histones and their posttranslational modifications...
  14. ncbi request reprint Association by guilt: identification of DLX5 as a target for MeCP2 provides a molecular link between genomic imprinting and Rett syndrome
    Sharmila Bapat
    National Centre for Cell Science, Ganeshkhind, Pune, India
    Bioessays 27:676-80. 2005
    ..This altered expression of Dlx5 through loss of silent chromatin loop formation provides a molecular mechanism underlying RTT and proposes a novel role for MeCP2 in chromatin organization and imprinting...
  15. doi request reprint Modulation of signal transduction pathways in lymphocytes due to sub-lethal toxicity of chlorinated phenol
    Amita Limaye
    National Centre for Cell Science, NCCS Complex, University of Pune Campus, Ganeshkhind, Pune, India
    Toxicol Lett 179:23-8. 2008
    ..We propose that PCP, a potent pollutant, imparts its cytotoxicity by evading the immune response by simultaneously affecting multiple signaling pathways in lymphocytes...
  16. pmc Stimulation of Tat-independent transcriptional processivity from the HIV-1 LTR promoter by matrix attachment regions
    Shravanti Rampalli
    National Center for Cell Science, Pune University Campus, Ganeshkhind, Pune 411007, India
    Nucleic Acids Res 31:3248-56. 2003
    ....
  17. ncbi request reprint GST fusion vector with caspase-6 cleavage site for removal of fusion tag during column purification
    Prabhat Kumar Purbey
    National Centre for Cell Science, Ganeshkhind, Pune, India
    Biotechniques 38:360, 362, 364 passim. 2005
  18. ncbi request reprint Direct interaction with and activation of p53 by SMAR1 retards cell-cycle progression at G2/M phase and delays tumor growth in mice
    Ruchika Kaul
    National Center for Cell Science, Pune University Campus, Pune, India
    Int J Cancer 103:606-15. 2003
    ..These data together suggest that SMAR1 is the only known MARBP that delays tumor progression via direct activation and interaction with tumor-suppressor p53...