Sanjeev Galande

Summary

Affiliation: National Centre for Cell Science
Country: India

Publications

  1. ncbi request reprint Chromatin (dis)organization and cancer: BUR-binding proteins as biomarkers for cancer
    Sanjeev Galande
    National Center for Cell Science, Ganeshkhind, Pune 411 007, India
    Curr Cancer Drug Targets 2:157-90. 2002
  2. pmc PDZ domain-mediated dimerization and homeodomain-directed specificity are required for high-affinity DNA binding by SATB1
    Prabhat Kumar Purbey
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Nucleic Acids Res 36:2107-22. 2008
  3. pmc Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Pune, India
    PLoS Biol 8:e1000296. 2010
  4. ncbi request reprint The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1
    Sanjeev Galande
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Curr Opin Genet Dev 17:408-14. 2007
  5. ncbi request reprint Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo
    P Pavan Kumar
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Mol Cell 22:231-43. 2006
  6. pmc Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1
    Prabhat Kumar Purbey
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    Mol Cell Biol 29:1321-37. 2009
  7. pmc SATB1-binding sequences and Alu-like motifs define a unique chromatin context in the vicinity of human immunodeficiency virus type 1 integration sites
    Pavan P Kumar
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    J Virol 81:5617-27. 2007
  8. ncbi request reprint Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus
    Pavan P Kumar
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Nat Cell Biol 9:45-56. 2007
  9. pmc Displacement of SATB1-bound histone deacetylase 1 corepressor by the human immunodeficiency virus type 1 transactivator induces expression of interleukin-2 and its receptor in T cells
    P Pavan Kumar
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    Mol Cell Biol 25:1620-33. 2005
  10. doi request reprint Phosphorylation-dependent regulation of SATB1, the higher-order chromatin organizer and global gene regulator
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Maharashtra, India
    Methods Mol Biol 647:317-35. 2010

Collaborators

  • Debashis Mitra
  • Samit Chattopadhyay
  • Henning Urlaub
  • Manoj Kumar Bhat
  • Jomon Joseph
  • Prabhat Kumar Purbey
  • Dimple Notani
  • P Pavan Kumar
  • Ranveer S Jayani
  • Pavan P Kumar
  • Amita S Limaye
  • Sameet Mehta
  • Amita Limaye
  • Mithila Burute
  • Praveena L Ramanujam
  • Kamalvishnu P Gottimukkala
  • Sunita Singh
  • Hemant J Purohit
  • Dyavar S Ravi
  • P Cyril Jayakumar
  • Milind S Patole
  • Sharmila Bapat
  • Shravanti Rampalli
  • Ruchika Kaul
  • Kamal Gottimukkala
  • Chandan Kumar-Sinha
  • Madhujit V Damle
  • Atya Kapley
  • K N Ganesh
  • Hatim F Daginawala
  • Giridhar M Taori
  • Rajpal S Kashyap
  • Ramesh R Bhonde
  • Dhananjay V Raje
  • Oliver Bischof
  • Anne Dejean
  • Chandan Kumar Sinha
  • P D Deepalakshmi
  • Asavari Kulkarni
  • Pavan Kumar
  • Sujoy Mukherjee
  • Farid Ahmed
  • Rishiraj Chhipa
  • Devraj Mogare

Detail Information

Publications19

  1. ncbi request reprint Chromatin (dis)organization and cancer: BUR-binding proteins as biomarkers for cancer
    Sanjeev Galande
    National Center for Cell Science, Ganeshkhind, Pune 411 007, India
    Curr Cancer Drug Targets 2:157-90. 2002
    ..Experimental strategies by which these proteins can be exploited as carcinoma-specific diagnostic markers and as targets for antineoplastic therapy are discussed...
  2. pmc PDZ domain-mediated dimerization and homeodomain-directed specificity are required for high-affinity DNA binding by SATB1
    Prabhat Kumar Purbey
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Nucleic Acids Res 36:2107-22. 2008
    ..These studies provide mechanistic insights into the mode of DNA binding and its effect on the regulation of transcription by SATB1...
  3. pmc Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Pune, India
    PLoS Biol 8:e1000296. 2010
    ....
  4. ncbi request reprint The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1
    Sanjeev Galande
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Curr Opin Genet Dev 17:408-14. 2007
    ..At genome-wide level, SATB1 seems to play a role in organization of the transcriptionally poised chromatin...
  5. ncbi request reprint Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo
    P Pavan Kumar
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Mol Cell 22:231-43. 2006
    ....
  6. pmc Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1
    Prabhat Kumar Purbey
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    Mol Cell Biol 29:1321-37. 2009
    ..Collectively, these results provide a mechanistic insight into the role of SATB1-CtBP1 interaction in the repression and derepression of SATB1 target genes during Wnt signaling in T cells...
  7. pmc SATB1-binding sequences and Alu-like motifs define a unique chromatin context in the vicinity of human immunodeficiency virus type 1 integration sites
    Pavan P Kumar
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    J Virol 81:5617-27. 2007
    ..We propose that definitive sequence features such as the Alu-like motifs and SATB1-binding sites provide a unique chromatin context in vivo which is preferentially targeted by the HIV-1 integration machinery...
  8. ncbi request reprint Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus
    Pavan P Kumar
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Nat Cell Biol 9:45-56. 2007
    ..Our studies identify PML and SATB1 as a regulatory complex that governs transcription by orchestrating dynamic chromatin-loop architecture...
  9. pmc Displacement of SATB1-bound histone deacetylase 1 corepressor by the human immunodeficiency virus type 1 transactivator induces expression of interleukin-2 and its receptor in T cells
    P Pavan Kumar
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    Mol Cell Biol 25:1620-33. 2005
    ..These results suggest a novel mechanism by which HIV-1 Tat might overcome SATB1-mediated repression in T cells...
  10. doi request reprint Phosphorylation-dependent regulation of SATB1, the higher-order chromatin organizer and global gene regulator
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Maharashtra, India
    Methods Mol Biol 647:317-35. 2010
    ..Finally, we describe a functional assay to monitor the effect of phosphorylation on transcription activity of SATB1 in vivo using MAR-linked reporter assay, in the presence and absence of PKC inhibitors...
  11. ncbi request reprint N-terminal PDZ-like domain of chromatin organizer SATB1 contributes towards its function as transcription regulator
    Dimple Notani
    National Centre for Cell Science, Ganeshkhind, Pune 411 007, India
    J Biosci 36:461-9. 2011
    ..These studies clearly demonstrated the role of PDZ domain of SATB1 in global gene regulation presumably through its interaction with other cellular proteins...
  12. ncbi request reprint pC6-2/caspase-6 system to purify glutathione-S-transferase-free recombinant fusion proteins expressed in Escherichia coli
    Prabhat Kumar Purbey
    National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411007, India
    Nat Protoc 1:1820-7. 2006
    ..Here, we describe the detailed protocol for purifying proteins using our pC6-2/caspase-6 expression and purification system. The cleavage by caspase-6 occurs in <30 min and the entire procedure can be completed in 2 d...
  13. doi request reprint Chromatin organizer SATB1 is an important determinant of T-cell differentiation
    Mithila Burute
    Centre of Excellence in Epigenetics, Indian Institute of Science Education and Research, Pune, India
    Immunol Cell Biol 90:852-9. 2012
    ..We discuss how regulation of the activity of SATB1 has a critical role in driving these two important differentiation pathways in T cells...
  14. doi request reprint Studying histone modifications and their genomic functions by employing chromatin immunoprecipitation and immunoblotting
    Ranveer S Jayani
    National Centre for Cell Science, Ganeshkhind, Pune 411007, India
    Methods Cell Biol 98:35-56. 2010
    ..We also describe the protocol for immunoblot analysis of histones using antibodies against key histone modifications. This chapter will serve as a useful resource in the study of histones and their posttranslational modifications...
  15. ncbi request reprint GST fusion vector with caspase-6 cleavage site for removal of fusion tag during column purification
    Prabhat Kumar Purbey
    National Centre for Cell Science, Ganeshkhind, Pune, India
    Biotechniques 38:360, 362, 364 passim. 2005
  16. ncbi request reprint Association by guilt: identification of DLX5 as a target for MeCP2 provides a molecular link between genomic imprinting and Rett syndrome
    Sharmila Bapat
    National Centre for Cell Science, Ganeshkhind, Pune, India
    Bioessays 27:676-80. 2005
    ..This altered expression of Dlx5 through loss of silent chromatin loop formation provides a molecular mechanism underlying RTT and proposes a novel role for MeCP2 in chromatin organization and imprinting...
  17. pmc Stimulation of Tat-independent transcriptional processivity from the HIV-1 LTR promoter by matrix attachment regions
    Shravanti Rampalli
    National Center for Cell Science, Pune University Campus, Ganeshkhind, Pune 411007, India
    Nucleic Acids Res 31:3248-56. 2003
    ....
  18. doi request reprint Modulation of signal transduction pathways in lymphocytes due to sub-lethal toxicity of chlorinated phenol
    Amita Limaye
    National Centre for Cell Science, NCCS Complex, University of Pune Campus, Ganeshkhind, Pune, India
    Toxicol Lett 179:23-8. 2008
    ..We propose that PCP, a potent pollutant, imparts its cytotoxicity by evading the immune response by simultaneously affecting multiple signaling pathways in lymphocytes...
  19. ncbi request reprint Direct interaction with and activation of p53 by SMAR1 retards cell-cycle progression at G2/M phase and delays tumor growth in mice
    Ruchika Kaul
    National Center for Cell Science, Pune University Campus, Pune, India
    Int J Cancer 103:606-15. 2003
    ..These data together suggest that SMAR1 is the only known MARBP that delays tumor progression via direct activation and interaction with tumor-suppressor p53...