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Genomes and GenesSpecies | Anjana MunshiSummaryCountry: India Publications
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Publications
Association of the -344C/T aldosterone synthase (CYP11B2) gene variant with hypertension and strokeAnjana Munshi
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
J Neurol Sci 296:34-8. 2010..In conclusion our study suggests that -344T allele of CYP11B2 gene is an important risk factor for hypertension and ischemic stroke. However, this is a preliminary study and the results need to be confirmed in a larger cohort...
Interleukin-10-1082 promoter polymorphism and ischemic stroke risk in a South Indian populationAnjana Munshi
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India
Cytokine 52:221-4. 2010..001). Moreover, hypertensive and diabetic individuals bearing A allele of IL-10 gene in high frequency were found to be more predisposed to stroke...
Association of LPL gene variant and LDL, HDL, VLDL cholesterol and triglyceride levels with ischemic stroke and its subtypesAnjana Munshi
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
J Neurol Sci 318:51-4. 2012..Further, this polymorphism is significantly associated with intracranial large artery atherosclerosis which is the most frequent subtype in our region...
Genetic variation in MDR1, LPL and eNOS genes and the response to atorvastatin treatment in ischemic strokeAnjana Munshi
Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
Hum Genet 131:1775-81. 2012..In conclusion the individuals with HindIII (-/-) genotype of LPL and CC genotype of MDR1 gene would benefit more from atorvastatin therapy...
Association of SNP41, SNP56 and a novel SNP in PDE4D gene with stroke and its subtypesAnjana Munshi
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
Gene 506:31-5. 2012..In conclusion PDE4D gene plays a key part in the pathogenesis of ischemic stroke in the South Indian population from Andhra Pradesh...
Estrogen receptor α genetic variants and the risk of stroke in a South Indian population from Andhra PradeshAnjana Munshi
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
Clin Chim Acta 411:1817-21. 2010..Recent findings have suggested that stroke has a strong genetic component. Evidence suggests that variations in the estrogen receptor α (ESR1) gene may influence stroke risk...
Depletion of serum zinc in ischemic stroke patientsA Munshi
Institute of Genetics and Hospital for Genetic Diseases, O U, Begumpet, Hyderabad, India
Methods Find Exp Clin Pharmacol 32:433-6. 2010..Zinc may represent an independent risk factor for stroke and therefore a possible target for prevention. Additional studies are needed to further examine the role of zinc in the pathogenesis of stroke...
Lack of association of G779A ZHX-2 gene variant with HbF levels in β-thalassemia majorAnjana Munshi
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India
Eur J Haematol 86:502-6. 2011....
Association of 1347 G/A cytochrome P450 4F2 (CYP4F2) gene variant with hypertension and strokeAnjana Munshi
Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
Mol Biol Rep 39:1677-82. 2012..001). In conclusion our study suggests that 1347A allele of CYP4F2 gene is an important risk factor for hypertension and ischemic stroke...
Genetic basis of stroke: an overviewAnjana Munshi
Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases OU, Begumpet, Hyderabad 500 016, India
Neurol India 58:185-90. 2010..Further studies will hopefully tell us how far the genetic information will assist us to tailor clinical and therapeutic decisions to an individual's genotype...
VNTR polymorphism in intron 4 of the eNOS gene and the risk of ischemic stroke in a South Indian populationAnjana Munshi
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
Brain Res Bull 82:247-50. 2010..We did not find significant association of this polymorphism with any specific stroke subtype. Further hypertensives bearing 4a allele in high frequency are more predisposed to stroke...
Angiotensin-converting enzyme insertion/deletion polymorphism and the risk of ischemic stroke in a South Indian populationAnjana Munshi
Institute of Genetics and Hospital for Genetic Diseases, Begumpet, Hyderabad 500016, India
J Neurol Sci 272:132-5. 2008..Moreover, ACE gene polymorphism was found to contribute to the risk of developing intracranial large artery atherosclerosis, which is the most frequent subtype in this region...
Stroke genetics--focus on PDE4D geneAnjana Munshi
Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Begumpet, Hyderabad, India
Int J Stroke 3:188-92. 2008..Replication studies in non-Icelanders have yielded variable results. There may be obvious racial differences in the prevalence of these mutations but still many questions remain unsolved regarding the role of PDE4D in stroke development...
Inherited hemoglobin disorders in Andhra Pradesh, India: a population studyAnjana Munshi
Institute of Genetics and Hospital for Genetic Diseases, Begumpet Hyderabad 500016, AP, India
Clin Chim Acta 400:117-9. 2009..Beta-thalassemia is the most common monogenic disorder in India. Molecular characterization of this disease has revealed an extremely heterogeneous picture...
Histone modifications dictate specific biological readoutsAnjana Munshi
Institute of Genetics and Hospital for Genetic Diseases, Begumpet, Hyderabad, India
J Genet Genomics 36:75-88. 2009..Increasing evidence suggests that many proteins bear multiple, distinct modifications, and the ability of one modification to antagonize or synergize the deposition of another can have significant biological consequences...
Phosphodiesterase 4D (PDE4D) gene variants and the risk of ischemic stroke in a South Indian populationAnjana Munshi
Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Begumpet, Hyderabad 500016, India
J Neurol Sci 285:142-5. 2009..The association with other subtypes was found to be insignificant. Further, SNP 83 was found to be associated significantly with some conventional stroke risk factors like diabetes and smoking...
Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativaGowhar Shafi
Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Hyderabad, India
Cancer Cell Int 9:29. 2009....
Association of genetic variants of fibrinolytic system with stroke and stroke subtypesM Sai Babu
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
Gene 495:76-80. 2012....
Association of C3435T multi drug resistance gene-1 polymorphism with aspirin resistance in ischemic stroke and its subtypesVandana Sharma
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
J Neurol Sci 315:72-6. 2012..Our results indicate that the risk of aspirin resistance is more in patients with 3435TT genotype than in those with CC genotype. However, this is a preliminary study and a large study of replication is needed to confirm our results...
C-reactive protein and nitric oxide levels in ischemic stroke and its subtypes: correlation with clinical outcomeK Rajeshwar
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
Inflammation 35:978-84. 2012..In conclusion, hsCRP and NO levels predict the incidence of ischemic stroke and hsCRP is an independent prognostic factor of poor outcome at 3 months...
Association of COX-2 rs20417 with aspirin resistanceVandana Sharma
Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, 500016, India
J Thromb Thrombolysis 35:95-9. 2013..Therefore, the carriers of C allele of COX-2 -765G/C polymorphism are more prone to AR in comparison with non-carriers. These results support a potential role of -765G/C COX-2 gene polymorphism with AR in ischemic stroke patients...
Association of estrogen receptor alpha gene polymorphisms with BMD and their affect on estradiol levels in pre- and postmenopausal women in south Indian population from Andhra PradeshYasovanthi Jeedigunta
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, A P, India
Clin Chim Acta 411:597-600. 2010..Therefore the present study is aimed to investigate the role of ESR1 gene polymorphisms and its influence on estradiol levels and BMD in osteoporotic women of Indian ethnicity...
Serum albumin levels in ischemic stroke and its subtypes: Correlation with clinical outcomeMallemoggala Sai Babu
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, India Dr NTR University of Health Sciences, Vijayawada, Andhra Pradesh
Nutrition 29:872-5. 2013..The present study was carried out to investigate the association of serum albumin levels with outcome in ischemic stroke and its subtypes...
Genomic imprinting - the story of the other half and the conflicts of silencingAnjana Munshi
Department of Genetics, Shadan PG Centre for Biosciences, Khairtabad Hyderabad 500016, India
J Genet Genomics 34:93-103. 2007..Post genomic technologies might ultimately lead to a better understanding of the 'imprinting effects'...
Cytokine gene polymorphisms in the susceptibility to acute coronary syndromeBaddela M V Srikanth Babu
Institute of Genetics and Hospital for Genetic Disease, Osmania University, Hyderabad, India
Genet Test Mol Biomarkers 16:359-65. 2012....
Artemisia absinthium (AA): a novel potential complementary and alternative medicine for breast cancerGowhar Shafi
Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, 500016 Andhra Pradesh, India
Mol Biol Rep 39:7373-9. 2012..This might lead to its possible development as a therapeutic agent for breast cancer following further investigations...
The M235T polymorphism of the angiotensinogen gene in South Indian patients of hypertrophic cardiomyopathy- Polugari Prem Kumar Manohar Rao
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India
J Renin Angiotensin Aldosterone Syst 12:238-42. 2011..The PCR products were subjected to restriction digestion with the enzyme SfaNI...
MicroRNA signatures in neurological disordersGowhar Shafi
Institute of Genetics and Hospital for Genetic Diseases, Begumpet Hyderabad AP, India
Can J Neurol Sci 37:177-85. 2010....
Genetics of nonalcoholic Fatty liver disease: an overviewJharna Puppala
Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
J Genet Genomics 40:15-22. 2013..Specific variants of different genes have been shown to present a risk for NAFLD. Genetic studies might be helpful in the management of the disease by developing novel treatment strategies based on individual's genotype...
Antioxidant potential of curcumin against oxidative insult induced by pentylenetetrazol in epileptic ratsV Sharma
Institute of Genetics and Hospital for Genetic Diseases, O U, Hyderabad, India
Methods Find Exp Clin Pharmacol 32:227-32. 2010..Combined treatment with curcumin and carbamazepine (3.6 mg/kg orally) also gave similar results, indicating that the potent antioxidant curcumin can be used as an adjuvant in antiepileptic therapy...
