Anjana Munshi

Summary

Country: India

Publications

  1. doi request reprint Genetic basis of stroke: an overview
    Anjana Munshi
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases OU, Begumpet, Hyderabad 500 016, India
    Neurol India 58:185-90. 2010
  2. doi request reprint Association of the -344C/T aldosterone synthase (CYP11B2) gene variant with hypertension and stroke
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    J Neurol Sci 296:34-8. 2010
  3. doi request reprint Interleukin-10-1082 promoter polymorphism and ischemic stroke risk in a South Indian population
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India
    Cytokine 52:221-4. 2010
  4. doi request reprint Association of 1347 G/A cytochrome P450 4F2 (CYP4F2) gene variant with hypertension and stroke
    Anjana Munshi
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Mol Biol Rep 39:1677-82. 2012
  5. doi request reprint Association of LPL gene variant and LDL, HDL, VLDL cholesterol and triglyceride levels with ischemic stroke and its subtypes
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    J Neurol Sci 318:51-4. 2012
  6. doi request reprint Genetic variation in MDR1, LPL and eNOS genes and the response to atorvastatin treatment in ischemic stroke
    Anjana Munshi
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Hum Genet 131:1775-81. 2012
  7. doi request reprint Association of SNP41, SNP56 and a novel SNP in PDE4D gene with stroke and its subtypes
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Gene 506:31-5. 2012
  8. doi request reprint Estrogen receptor α genetic variants and the risk of stroke in a South Indian population from Andhra Pradesh
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Clin Chim Acta 411:1817-21. 2010
  9. doi request reprint Depletion of serum zinc in ischemic stroke patients
    A Munshi
    Institute of Genetics and Hospital for Genetic Diseases, O U, Begumpet, Hyderabad, India
    Methods Find Exp Clin Pharmacol 32:433-6. 2010
  10. doi request reprint VNTR polymorphism in intron 4 of the eNOS gene and the risk of ischemic stroke in a South Indian population
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Brain Res Bull 82:247-50. 2010

Collaborators

  • Ali A Alshatwi
  • James Joseph
  • S Kaul
  • M P J S Anandraj
  • A Jyothy
  • Vandana Sharma
  • Gowhar Shafi
  • Sneha Dadheech
  • Amal Al-Hazzani
  • Uzma Shaheen
  • M Sai Babu
  • Mallemoggala Sai Babu
  • Jharna Puppala
  • Akka Jyothy
  • K Rajeshwar
  • N Balakrishna
  • Baddela M V Srikanth Babu
  • T Surya Prabha
  • Jyothy Akka
  • - Polugari Prem Kumar Manohar Rao
  • Tarique N Hasan
  • Yasovanthi Jeedigunta
  • V Sharma
  • T Suryaprabha
  • D K V Prasad
  • Y R Ahuja
  • Siva Prasad Siddapuram
  • Koppula Rajeshwar
  • A Venkateswara Rao
  • Mohammed Dyia Hussien
  • Suman Jain
  • Hanmathrao Surekha Rani
  • A Jyothi
  • Sitara Roy
  • Gaddam Suman Latha
  • Polugari Prem Kumar Manohar Rao
  • Bhomireddy Pulla Reddy
  • Vanacherla Hari Sai Priya
  • V Dayasagar Rao
  • Naveed Ahmed Syed
  • Amal A Al-Hazzani
  • - Potham Sampath Kumar
  • Ratnam Mullapudi
  • Murlidhar Sadhnani
  • Annam Sharath
  • - Gundala Anil Krishna
  • Venkateshwari Ananthapur
  • Pulla Reddy Bhoomi Reddy
  • Venkata Karunakar Kolla
  • Nishat Aliya
  • B Nehru
  • G Narasimulu
  • David Ky Lei

Detail Information

Publications33

  1. doi request reprint Genetic basis of stroke: an overview
    Anjana Munshi
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases OU, Begumpet, Hyderabad 500 016, India
    Neurol India 58:185-90. 2010
    ..Further studies will hopefully tell us how far the genetic information will assist us to tailor clinical and therapeutic decisions to an individual's genotype...
  2. doi request reprint Association of the -344C/T aldosterone synthase (CYP11B2) gene variant with hypertension and stroke
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    J Neurol Sci 296:34-8. 2010
    ..In conclusion our study suggests that -344T allele of CYP11B2 gene is an important risk factor for hypertension and ischemic stroke. However, this is a preliminary study and the results need to be confirmed in a larger cohort...
  3. doi request reprint Interleukin-10-1082 promoter polymorphism and ischemic stroke risk in a South Indian population
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India
    Cytokine 52:221-4. 2010
    ..001). Moreover, hypertensive and diabetic individuals bearing A allele of IL-10 gene in high frequency were found to be more predisposed to stroke...
  4. doi request reprint Association of 1347 G/A cytochrome P450 4F2 (CYP4F2) gene variant with hypertension and stroke
    Anjana Munshi
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Mol Biol Rep 39:1677-82. 2012
    ..001). In conclusion our study suggests that 1347A allele of CYP4F2 gene is an important risk factor for hypertension and ischemic stroke...
  5. doi request reprint Association of LPL gene variant and LDL, HDL, VLDL cholesterol and triglyceride levels with ischemic stroke and its subtypes
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    J Neurol Sci 318:51-4. 2012
    ..Further, this polymorphism is significantly associated with intracranial large artery atherosclerosis which is the most frequent subtype in our region...
  6. doi request reprint Genetic variation in MDR1, LPL and eNOS genes and the response to atorvastatin treatment in ischemic stroke
    Anjana Munshi
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Hum Genet 131:1775-81. 2012
    ..In conclusion the individuals with HindIII (-/-) genotype of LPL and CC genotype of MDR1 gene would benefit more from atorvastatin therapy...
  7. doi request reprint Association of SNP41, SNP56 and a novel SNP in PDE4D gene with stroke and its subtypes
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Gene 506:31-5. 2012
    ..In conclusion PDE4D gene plays a key part in the pathogenesis of ischemic stroke in the South Indian population from Andhra Pradesh...
  8. doi request reprint Estrogen receptor α genetic variants and the risk of stroke in a South Indian population from Andhra Pradesh
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Clin Chim Acta 411:1817-21. 2010
    ..Recent findings have suggested that stroke has a strong genetic component. Evidence suggests that variations in the estrogen receptor α (ESR1) gene may influence stroke risk...
  9. doi request reprint Depletion of serum zinc in ischemic stroke patients
    A Munshi
    Institute of Genetics and Hospital for Genetic Diseases, O U, Begumpet, Hyderabad, India
    Methods Find Exp Clin Pharmacol 32:433-6. 2010
    ..Zinc may represent an independent risk factor for stroke and therefore a possible target for prevention. Additional studies are needed to further examine the role of zinc in the pathogenesis of stroke...
  10. doi request reprint VNTR polymorphism in intron 4 of the eNOS gene and the risk of ischemic stroke in a South Indian population
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Brain Res Bull 82:247-50. 2010
    ..We did not find significant association of this polymorphism with any specific stroke subtype. Further hypertensives bearing 4a allele in high frequency are more predisposed to stroke...
  11. pmc Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativa
    Gowhar Shafi
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Hyderabad, India
    Cancer Cell Int 9:29. 2009
    ....
  12. doi request reprint Phosphodiesterase 4D (PDE4D) gene variants and the risk of ischemic stroke in a South Indian population
    Anjana Munshi
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Begumpet, Hyderabad 500016, India
    J Neurol Sci 285:142-5. 2009
    ..The association with other subtypes was found to be insignificant. Further, SNP 83 was found to be associated significantly with some conventional stroke risk factors like diabetes and smoking...
  13. doi request reprint Histone modifications dictate specific biological readouts
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Begumpet, Hyderabad, India
    J Genet Genomics 36:75-88. 2009
    ..Increasing evidence suggests that many proteins bear multiple, distinct modifications, and the ability of one modification to antagonize or synergize the deposition of another can have significant biological consequences...
  14. doi request reprint Inherited hemoglobin disorders in Andhra Pradesh, India: a population study
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Begumpet Hyderabad 500016, AP, India
    Clin Chim Acta 400:117-9. 2009
    ..Beta-thalassemia is the most common monogenic disorder in India. Molecular characterization of this disease has revealed an extremely heterogeneous picture...
  15. doi request reprint Stroke genetics--focus on PDE4D gene
    Anjana Munshi
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Begumpet, Hyderabad, India
    Int J Stroke 3:188-92. 2008
    ..Replication studies in non-Icelanders have yielded variable results. There may be obvious racial differences in the prevalence of these mutations but still many questions remain unsolved regarding the role of PDE4D in stroke development...
  16. doi request reprint Angiotensin-converting enzyme insertion/deletion polymorphism and the risk of ischemic stroke in a South Indian population
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Begumpet, Hyderabad 500016, India
    J Neurol Sci 272:132-5. 2008
    ..Moreover, ACE gene polymorphism was found to contribute to the risk of developing intracranial large artery atherosclerosis, which is the most frequent subtype in this region...
  17. doi request reprint Lack of association of G779A ZHX-2 gene variant with HbF levels in β-thalassemia major
    Anjana Munshi
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India
    Eur J Haematol 86:502-6. 2011
    ....
  18. doi request reprint Association of genetic variants of fibrinolytic system with stroke and stroke subtypes
    M Sai Babu
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Gene 495:76-80. 2012
    ....
  19. doi request reprint Association of COX-2 rs20417 with aspirin resistance
    Vandana Sharma
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, 500016, India
    J Thromb Thrombolysis 35:95-9. 2013
    ..Therefore, the carriers of C allele of COX-2 -765G/C polymorphism are more prone to AR in comparison with non-carriers. These results support a potential role of -765G/C COX-2 gene polymorphism with AR in ischemic stroke patients...
  20. doi request reprint Association of ALOX5AP1 SG13S114T/A variant with ischemic stroke, stroke subtypes and aspirin resistance
    Vandana Sharma
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    J Neurol Sci 331:108-13. 2013
    ..Our results indicate that the individuals bearing AA genotype of ALOX5AP1 SG13S114T/A polymorphism are more prone to stroke and bad outcome as well as with aspirin resistance than TA and TT genotypes...
  21. doi request reprint Association of C3435T multi drug resistance gene-1 polymorphism with aspirin resistance in ischemic stroke and its subtypes
    Vandana Sharma
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    J Neurol Sci 315:72-6. 2012
    ..Our results indicate that the risk of aspirin resistance is more in patients with 3435TT genotype than in those with CC genotype. However, this is a preliminary study and a large study of replication is needed to confirm our results...
  22. doi request reprint C-reactive protein and nitric oxide levels in ischemic stroke and its subtypes: correlation with clinical outcome
    K Rajeshwar
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India
    Inflammation 35:978-84. 2012
    ..In conclusion, hsCRP and NO levels predict the incidence of ischemic stroke and hsCRP is an independent prognostic factor of poor outcome at 3 months...
  23. doi request reprint Serum albumin levels in ischemic stroke and its subtypes: correlation with clinical outcome
    Mallemoggala Sai Babu
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, India
    Nutrition 29:872-5. 2013
    ..The present study was carried out to investigate the association of serum albumin levels with outcome in ischemic stroke and its subtypes...
  24. doi request reprint Three most common nonsynonymous UGT1A6*2 polymorphisms (Thr181Ala, Arg184Ser and Ser7Ala) and therapeutic response to deferiprone in β-thalassemia major patients
    Sneha Dadheech
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad 500016, India Dr NTR University of Health Sciences, Vijayawada, A P, India
    Gene 531:301-5. 2013
    ..In addition to this haplotype analysis was also carried out. However, we did not find any specific haplotype to be significantly associated with the deferiprone response in β-thalassemia major patients...
  25. doi request reprint Association of estrogen receptor alpha gene polymorphisms with BMD and their affect on estradiol levels in pre- and postmenopausal women in south Indian population from Andhra Pradesh
    Yasovanthi Jeedigunta
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, A P, India
    Clin Chim Acta 411:597-600. 2010
    ..Therefore the present study is aimed to investigate the role of ESR1 gene polymorphisms and its influence on estradiol levels and BMD in osteoporotic women of Indian ethnicity...
  26. ncbi request reprint Genomic imprinting - the story of the other half and the conflicts of silencing
    Anjana Munshi
    Department of Genetics, Shadan PG Centre for Biosciences, Khairtabad Hyderabad 500016, India
    J Genet Genomics 34:93-103. 2007
    ..Post genomic technologies might ultimately lead to a better understanding of the 'imprinting effects'...
  27. doi request reprint Significance of MDR1 gene polymorphism C3435T in predicting drug response in epilepsy
    Uzma Shaheen
    Institute of Genetics and Hospital for Genetic Diseases, OU, Begumpet 500016, India Dr NTR University of Health Sciences, Vijayawada, India
    Epilepsy Res 108:251-6. 2014
    ....
  28. doi request reprint Cytokine gene polymorphisms in the susceptibility to acute coronary syndrome
    Baddela M V Srikanth Babu
    Institute of Genetics and Hospital for Genetic Disease, Osmania University, Hyderabad, India
    Genet Test Mol Biomarkers 16:359-65. 2012
    ....
  29. doi request reprint Artemisia absinthium (AA): a novel potential complementary and alternative medicine for breast cancer
    Gowhar Shafi
    Department of Molecular Biology, Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, 500016 Andhra Pradesh, India
    Mol Biol Rep 39:7373-9. 2012
    ..This might lead to its possible development as a therapeutic agent for breast cancer following further investigations...
  30. ncbi request reprint MicroRNA signatures in neurological disorders
    Gowhar Shafi
    Institute of Genetics and Hospital for Genetic Diseases, Begumpet Hyderabad AP, India
    Can J Neurol Sci 37:177-85. 2010
    ....
  31. doi request reprint The M235T polymorphism of the angiotensinogen gene in South Indian patients of hypertrophic cardiomyopathy
    - Polugari Prem Kumar Manohar Rao
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India
    J Renin Angiotensin Aldosterone Syst 12:238-42. 2011
    ..The PCR products were subjected to restriction digestion with the enzyme SfaNI...
  32. doi request reprint Genetics of nonalcoholic Fatty liver disease: an overview
    Jharna Puppala
    Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India
    J Genet Genomics 40:15-22. 2013
    ..Specific variants of different genes have been shown to present a risk for NAFLD. Genetic studies might be helpful in the management of the disease by developing novel treatment strategies based on individual's genotype...
  33. doi request reprint Antioxidant potential of curcumin against oxidative insult induced by pentylenetetrazol in epileptic rats
    V Sharma
    Institute of Genetics and Hospital for Genetic Diseases, O U, Hyderabad, India
    Methods Find Exp Clin Pharmacol 32:227-32. 2010
    ..Combined treatment with curcumin and carbamazepine (3.6 mg/kg orally) also gave similar results, indicating that the potent antioxidant curcumin can be used as an adjuvant in antiepileptic therapy...