Research Topics
| Kakali MukherjeeSummaryCountry: India Publications
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Publications
Integrated approaches towards drug development from Ayurveda and other Indian system of medicinesPulok K Mukherjee
School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India
J Ethnopharmacol 103:25-35. 2006..The plant species mentioned in the ancient texts of these Ayurveda and other Indian systems of medicines may be explored with the modern scientific approaches for better leads in the health care...
Curcumin-phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in ratsKuntal Maiti
School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700 032, India
Int J Pharm 330:155-63. 2007..The result proved that curcumin-phospholipid complex has better hepatoprotective activity, owe to its superior antioxidant property, than free curcumin at the same dose level...
Enhancing bioavailability and hepatoprotective activity of andrographolide from Andrographis paniculata, a well-known medicinal food, through its herbosomeKuntal Maiti
School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700 032, India
J Sci Food Agric 90:43-51. 2010..The aim of this study was to formulate a herbosome of andrographolide with a naturally occurring phospholipid in order to enhance the bioavailability and hepatoprotective activity of andrographolide in rats...
Exploring the effect of Hesperetin-HSPC complex--a novel drug delivery system on the in vitro release, therapeutic efficacy and pharmacokineticsKuntal Maiti
Department of Pharmaceutical Technology, Faculty of Engineering and Technology, School of Natural Product Studies, Jadavpur University, Kolkata 700 032, India
AAPS PharmSciTech 10:943-50. 2009....
Antioxidant effect of Cytisus scoparius against carbon tetrachloride treated liver injury in ratsS Raja
School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India
J Ethnopharmacol 109:41-7. 2007..Based on these results, it was observed that Cytisus scoparius extract protects liver from oxidative stress induced by CCl(4) in rats and thus helps in evaluation of the traditional claim on this plant...
Enhanced oral bioavailability and antioxidant profile of ellagic acid by phospholipidsVenkatesh Murugan
Department of Pharmaceutical Technology, Faculty of Engineering and Technology, School of Natural Product Studies, Jadavpur University, Kolkata, India
J Agric Food Chem 57:4559-65. 2009..The experimental outcome highlighted better hepatoprotective activity of the EA complex due to its potential antioxidant property compared with the free EA tested at the same dose level...
Enhanced therapeutic potential of naringenin-phospholipid complex in ratsKuntal Maiti
School of Natural Product Studies, Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Kolkata - 700 032, India
J Pharm Pharmacol 58:1227-33. 2006..Phospholipid complex of naringenin produced better antioxidant activity than the free compound with a prolonged duration of action, which may be helpful in reducing the fast elimination of the molecule from body...
Cytisus scoparius link--a natural antioxidantRaja Sundararajan
Department of Pharmaceutical Technology, Jadavpur University, School of Natural Product Studies, Kolkata 700 032, India
BMC Complement Altern Med 6:8. 2006..The plant Cytisus scoparius contains the main constituent of flavone and flavonals. The present study was undertaken to evaluate the in vitro antioxidant activities of extract of aerial part of Cytisus scoparius...
Protective effect of biflavones from Araucaria bidwillii Hook in rat cerebral ischemia/reperfusion induced oxidative stressPulok K Mukherjee
School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India
Behav Brain Res 178:221-8. 2007..In conclusion the biflavone rich fraction from A. bidwillii was found to protect rat brain against I/R induced oxidative stress, and attributable to its antioxidant properties...
Determination of 6-gingerol in ginger (Zingiber officinale) using high-performance thin-layer chromatographySujay Rai
School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India
J Sep Sci 29:2292-5. 2006..79 to 99.84% showed the excellent reliability and reproducibility of the method. The proposed HPTLC method for quantitative monitoring of 6-gingerol in ginger can be used for routine quality testing of ginger extracts...
Validation of HPTLC method for the analysis of taraxerol in Clitoria ternateaVenkatesan Kumar
School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India
Phytochem Anal 19:244-50. 2008..The proposed HPTLC method for quantitative monitoring of taraxerol in C. ternatea can be used for routine quality testing of C. ternatea extract used in Ayurvedic formulations...
Plants of Indian origin in drug discoveryPulok K Mukherjee
Jadavpur University, School of Natural Product Studies, Department of Pharmaceutical Technology, Kolkata 700 032, India 91 33 24298313 91 33 2414 6046
Expert Opin Drug Discov 2:633-57. 2007..This review aims at highlighting aspects of drug development from Indian medicinal plants through the use of ethnobotany, ethnopharmacology and systems biology, with different approaches using metabolomics and allied fields...
Botanicals as medicinal food and their effects on drug metabolizing enzymesPulok K Mukherjee
School of Natural Product Studies, Dept of Pharmaceutical Technology, Jadavpur University, Kolkata 700 032, India
Food Chem Toxicol 49:3142-53. 2011..This article reviews the potential for drug interactions by herbal extracts through drug metabolizing enzymes...
Antioxidant activity of Nelumbo nucifera (sacred lotus) seedsSujay Rai
School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, 188 Raja S C Mullick Road, Kolkata 700 032, India
J Ethnopharmacol 104:322-7. 2006..Nelumbo nucifera seeds contain alkaloids, saponins, phenolics and carbohydrates. The results support significant antioxidant nature of HANN...
