Research Topics
Genomes and Genes
| Viswanathan MohanSummaryCountry: India Publications
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Publications
Glucose challenge increases circulating progenitor cells in Asian Indian male subjects with normal glucose tolerance which is compromised in subjects with pre-diabetes: A pilot studyAbel A Nathan
Laboratory of Vascular Biology, Department of Biotechnology, Indian Institute of Technology Madras IIT Madras, Chennai, India
BMC Endocr Disord 11:2. 2011..abstract:..
Obesity and abdominal obesity in Asian IndiansV Mohan
Madras Diabetes Research Foundation and Dr Mohan's Diabetes Specialities Centre 4, Conran Smith Road, Gopalapuram, Chennai 600086, India
Indian J Med Res 123:593-6. 2006
Pneumococcal infections and immunization in diabetic patientsV Mohan
Dr Mohan s Diabetes Specialities Centre, Chennai, India
J Postgrad Med 57:78-81. 2011..This article tries to provide a balanced review of the place of pneumococcal vaccination in Indian diabetic patients...
Anthropometric cut points for identification of cardiometabolic risk factors in an urban Asian Indian populationViswanathan Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai 600 086, India
Metabolism 56:961-8. 2007....
Prevalence and clinical profile of autosomal dominant type 2 diabetes from a diabetes centre in IndiaViswanathan Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, 4, Conran Smith Road, Gopalapuram, Chennai, India
Prim Care Diabetes 3:233-8. 2009..To study the prevalence, and clinical profile of autosomal dominant (AD) inherited forms of type 2 diabetes mellitus (T2DM)...
Screening with OGTT alone or in combination with the Indian diabetes risk score or genotyping of TCF7L2 to detect undiagnosed type 2 diabetes in Asian IndiansV Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, International Diabetes Federation Centre of Education, Chennai, India
Indian J Med Res 133:294-9. 2011....
Association of Indian Diabetes Risk Score with arterial stiffness in Asian Indian nondiabetic subjects: the Chennai Urban Rural Epidemiology Study (CURES-84)Viswanathan Mohan
Madras Diabetes Research Foundation, Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, Chennai, India
J Diabetes Sci Technol 4:337-43. 2010..In this study, we aim to determine the association of Indian Diabetes Risk Score (IDRS) with augmentation index (AI), a preclinical marker of early atherosclerotic changes...
Gene-environment interactions and the diabetes epidemic in IndiaV Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai, India
Forum Nutr 60:118-26. 2007..However, given the imprecision in measuring dietary intake, very large sample sizes would be needed for meaningful conclusions to be drawn...
Epidemiology of cardiovascular disease in type 2 diabetes: the Indian scenarioViswanathan Mohan
Madras Diabetes Research Foundation, Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, Chennai, India
J Diabetes Sci Technol 4:158-70. 2010..Preventive measures such as lifestyle modification with healthy diet, adequate physical activity, and decrease in stress could help prevent the twin epidemics of diabetes and CAD...
Prevalence of fibrocalculous pancreatic diabetes in Chennai in South IndiaViswanathan Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Noncommunicable Diseases Prevention and Control, Chennai, India
JOP 9:489-92. 2008..Fibrocalculous pancreatic diabetes is a form of diabetes secondary to chronic pancreatitis found in tropical, developing countries. There is no population based data on prevalence of fibrocalculous pancreatic diabetes...
A1C cut points to define various glucose intolerance groups in Asian IndiansViswanathan Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, World Health Organization Collaborating Centre for Non Communicable Diseases Prevention and Control, and International Diabetes Federation Centre for Education, Chennai, India
Diabetes Care 33:515-9. 2010..6%. CONCLUSIONS In Asian Indians, A1C cut points of 6.1 and 6.4% defined diabetes by 2-h postload plasma glucose or FPG criteria, respectively. A value of 5.6% optimally identified IGT or IFG but was <70% accurate...
Dietary carbohydrates, glycaemic load, food groups and newly detected type 2 diabetes among urban Asian Indian population in Chennai, India (Chennai Urban Rural Epidemiology Study 59)Viswanathan Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non Communicable diseases, Gopalapuram, Chennai, India
Br J Nutr 102:1498-506. 2009..31 (95 % CI 0.15, 0.62); P < 0.001). In urban south Indians, total dietary carbohydrate and glycaemic load are associated with increased, and dietary fibre with decreased, risk of type 2 diabetes...
Type 2 diabetes in Asian Indian youthViswanathan Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Chennai, India
Pediatr Diabetes 8:28-34. 2007..Primary prevention would require a multisectoral approach involving the government and non-governmental agencies with a focus on healthier lifestyles among children...
A single-center, open, comparative study of the effect of using self-monitoring of blood glucose to guide therapy on preclinical atherosclerotic markers in type 2 diabetic subjectsViswanathan Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Noncommunicable Diseases, International Diabetes Federation Centre of Education, Gopalapuram, Chennai, India
J Diabetes Sci Technol 4:942-8. 2010....
Urban rural differences in prevalence of self-reported diabetes in India--the WHO-ICMR Indian NCD risk factor surveillanceViswanathan Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, 4 Conran Smith Road, Gopalapuram, Chennai 600086, India
Diabetes Res Clin Pract 80:159-68. 2008..Urban residence, abdominal obesity and physical inactivity are the risk factors associated with diabetes in this study...
Association of low adiponectin levels with the metabolic syndrome--the Chennai Urban Rural Epidemiology Study (CURES-4)Viswanathan Mohan
Dr Mohan s MV Diabetes Specialities Centre and Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Metabolism 54:476-81. 2005..292; P<.00l). Lower adiponectin levels are associated with the metabolic syndrome per se and several of its components, particularly, diabetes, insulin resistance, and dyslipidemia in this urban south Indian population...
Clinical profile and complications of childhood- and adolescent-onset type 2 diabetes seen at a diabetes center in south IndiaAnandakumar Amutha
Dr Mohan s Diabetes Specialities Centre and Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India
Diabetes Technol Ther 14:497-504. 2012..This study describes the clinical characteristics of childhood- and adolescent-onset type 2 diabetes mellitus (CAT2DM) seen at a diabetes center in southern India...
Association of depression with complications of type 2 diabetes--the Chennai Urban Rural Epidemiology Study (CURES- 102)Subramani Poongothai
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non Communicable Diseases Prevention and Control IDF Centre of Education, Gopalapuram, Chennai, India
J Assoc Physicians India 59:644-8. 2011..The aim of the study was to assess the relationship between depression and diabetic complications among urban south Indian type 2 diabetic subjects [T2DM]...
Prevalence of sleep abnormalities and their association with metabolic syndrome among Asian Indians: Chennai Urban Rural Epidemiology Study (CURES-67)Mahadevan Roopa
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, World Health Organization WHO Collaborating Centre for Non Communicable Diseases Prevention and Control, Gopalapuram, Chennai, Tamilnadu, India
J Diabetes Sci Technol 4:1524-31. 2010..To estimate the prevalence of sleep abnormalities and their association with glucose intolerance and metabolic syndrome (MS) in the normal-weight urban South Indian population...
Refined grain consumption and the metabolic syndrome in urban Asian Indians (Chennai Urban Rural Epidemiology Study 57)Ganesan Radhika
Madras Diabetes Research Foundation, WHO Collaborating Centre for Non Communicable diseases, Gopalapuram, Chennai 600 086, India
Metabolism 58:675-81. 2009..83; 95% confidence interval, 4.72-12.99). Higher intake of refined grains was associated with insulin resistance and the metabolic syndrome in this population of Asian Indians who habitually consume high-carbohydrate diets...
A haplotype at the UCP1 gene locus contributes to genetic risk for type 2 diabetes in Asian Indians (CURES-72)Karani S Vimaleswaran
Madras Diabetes Research Foundation, Gopalapuram, Chennai 86, India
Metab Syndr Relat Disord 8:63-8. 2010..The objective of the study was to examine whether genetic variations in the UCP1 gene are associated with type 2 diabetes and its related traits in Asian Indians...
Uncoupling protein 2 and 3 gene polymorphisms and their association with type 2 diabetes in asian indiansKarani S Vimaleswaran
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Chennai, India
Diabetes Technol Ther 13:19-25. 2011..this study examined the association of -866G/A, Ala55Val, 45bpI/D, and -55C/T polymorphisms at the uncoupling protein (UCP) 3-2 loci with type 2 diabetes in Asian Indians...
Oxidized low-density lipoprotein and intimal medial thickness in subjects with glucose intolerance: the Chennai Urban Rural Epidemiology Study-25Kuppan Gokulakrishnan
Dr Mohan s Diabetes Specialities Centre and Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Metabolism 56:245-50. 2007..002, P < .001). In conclusion, OX-LDL levels increase with increasing glucose intolerance. Oxidized LDL is associated with carotid IMT and this is independent of age, sex, and glucose intolerance status...
Association of leukocyte count with varying degrees of glucose intolerance in Asian Indians: the Chennai Urban Rural Epidemiology Study (CURES-26)Kuppan Gokulakrishnan
Dr Mohan s Diabetes Specialities Centre and Madras Diabetes Research Foundation, WHO Collaborating Centre for Noncommunicable Disease Prevention and Control, Gopalapuram, Chennai, India
Metab Syndr Relat Disord 7:205-10. 2009..This study assessed the association of leukocyte count with different grades of glucose intolerance in Asian Indian subjects...
Prevalence of diabetes in Asian Indians based on glycated hemoglobin and fasting and 2-H post-load (75-g) plasma glucose (CURES-120)Adamsha Nazir
Dr Mohan s Diabetes Specialities Centre and Madras Diabetes Research Foundation, No 6 Conran Smith Road, Chennai, Tamil Nadu, India
Diabetes Technol Ther 14:665-8. 2012..We compared the prevalence of diabetes by fasting (FPG) and 2-h post-load (75-g) plasma glucose (2-h PG) and A1c criteria in an Asian Indian population...
Oxidative stress is independently associated with non-alcoholic fatty liver disease (NAFLD) in subjects with and without type 2 diabetesSandhya Narasimhan
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Clin Biochem 43:815-21. 2010..Our work is aimed at exploring the interrelationship of oxidative stress and insulin resistance in NAFLD subjects with and without type 2 diabetes in a population-based study...
Dietary profile of urban adult population in South India in the context of chronic disease epidemiology (CURES-68)Ganesan Radhika
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non Communicable diseases, International Diabetes Federation Centre of Education, 4 Conran Smith Road, Gopalapuram, Chennai, India
Public Health Nutr 14:591-8. 2011..Few dietary surveys have been done with reference to chronic diseases, such as diabetes, in India, which is considered to be the diabetes capital of the world. We report on the dietary intake of urban adults living in Chennai, South India...
Parental history of type 2 diabetes mellitus, metabolic syndrome, and cardiometabolic risk factors in Asian Indian adolescentsRanjit Mohan Anjana
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai 600 086, Tamilnadu, India
Metabolism 58:344-50. 2009....
Association of fruit and vegetable intake with cardiovascular risk factors in urban south IndiansGanesan Radhika
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, 4 Conran Smith Road, Gopalapuram, Chennai, India
Br J Nutr 99:398-405. 2008..Increased intake of fruits and vegetables could play a protective role against CVD in Asian Indians who have high rates of premature coronary artery disease...
Association of A1C with cardiovascular disease and metabolic syndrome in Asian Indians with normal glucose toleranceJames Dilley
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai, India
Diabetes Care 30:1527-32. 2007..This study examines the association of A1C with cardiovascular disease (CVD) risk factors, coronary artery disease (CAD), and metabolic syndrome in Asian Indians with normal glucose tolerance (NGT)...
Association of His1085His INSR gene polymorphism with type 2 diabetes in South IndiansDhanasekaran Bodhini
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, 4 Conran Smith Road, Gopalapuram, Chennai, India
Diabetes Technol Ther 14:696-700. 2012....
Accelerated aging as evidenced by increased telomere shortening and mitochondrial DNA depletion in patients with type 2 diabetesFinny Monickaraj
Department of Cell and Molecular Biology, Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, IDF Centre of Education, Gopalapuram, Chennai 600 086, Tamilnadu, India
Mol Cell Biochem 365:343-50. 2012..Our study emphasizes the clustering of accelerated aging features viz., shortened telomeres, decreased mtDNA content, hypoadiponectinemia, low HDL, and increased oxidative stress in Asian Indian type 2 diabetes patients...
Inflammatory markers in relation to nonalcoholic fatty liver disease in urban South IndiansGokulakrishnan Kuppan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, IDF Centre for Education, Gopalapuram, Chennai, India
Diabetes Technol Ther 14:152-8. 2012..This study assessed the association of inflammatory markers, high-sensitivity C-reactive protein (hsCRP), and total leukocyte count with nonalcoholic fatty liver disease (NAFLD) in urban South Indians...
Clinical profile of diabetes in the young seen between 1992 and 2009 at a specialist diabetes centre in south IndiaAnandakumar Amutha
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Colloborating Centre for Non communicable Diseases Prevention and Control, IDF Centre for Education, 4, Conran Smith Road, Gopalapuram, Chennai 600086, India
Prim Care Diabetes 5:223-9. 2011..To describe the trends and clinical profile of young diabetic patients (YD) attending a tertiary diabetes centre in south India...
Genetic variations in the FTO gene are associated with type 2 diabetes and obesity in south Indians (CURES-79)Kandaswamy Ramya
Madras Diabetes Research Foundation, ICMR Advanced Centre for Genomics of Type 2 Diabetes and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai, India
Diabetes Technol Ther 13:33-42. 2011....
Thr54 allele carriers of the Ala54Thr variant of FABP2 gene have associations with metabolic syndrome and hypertriglyceridemia in urban South IndiansKarani S Vimaleswaran
Department of Molecular Genetics Madras Diabetes Research Foundation, Gopalapuram, Chennai, 600 086, India
Metabolism 55:1222-6. 2006..02-1.51; P = .03), whereas for those carrying the Thr54Thr genotype, it was 1.812 (95% CI, 1.28-2.57; P = .001). Carriers of the Thr54 allele have associations with MS and hypertriglyceridemia in this urban South Indian population...
Prevalence of depression in a large urban South Indian population--the Chennai Urban Rural Epidemiology Study (CURES-70)Subramani Poongothai
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, Gopalapuram, Chennai, India
PLoS ONE 4:e7185. 2009..In India there are very few population based data on prevalence of depression. The aim of the study was to determine the prevalence of depression in an urban south Indian population...
Prevalence and clinical profile of metabolic obesity and phenotypic obesity in Asian IndiansLoganathan Geetha
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, International Diabetes Federation Centre of Education, Gopalapuram, Chennai, India
J Diabetes Sci Technol 5:439-46. 2011....
Effectiveness of exenatide in Asian Indians in a clinical care settingChidambarann Sudhakaran
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, World Health Organization Collaborating Centre for Non Communicable Diseases, International Diabetes Federation Centre of Education, Gopalapuram, Chennai, India
Diabetes Technol Ther 12:613-8. 2010..This study reports on the effectiveness of exenatide compared to insulin glargine or NPH insulin in patients with type 2 diabetes mellitus, unable to achieve glycemic control with oral glucose-lowering therapies in a clinical care setting...
Comparison of capillary whole blood versus venous plasma glucose estimations in screening for diabetes mellitus in epidemiological studies in developing countriesMiranda Priya
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Noncommunicable Diseases Prevention and Control, International Diabetes Federation Centre for Education, Chennai, India
Diabetes Technol Ther 13:586-91. 2011..This study compared capillary blood glucose (CBG) measurements with venous plasma glucose (VPG) measurements in screening for diabetes and prediabetes in epidemiological studies...
Increased levels of both Th1 and Th2 cytokines in subjects with metabolic syndrome (CURES-103)Jayagopi Surendar
Madras Diabetes Research Foundation, Chennai, India
Diabetes Technol Ther 13:477-82. 2011..The aim of the study was to look at the T-helper (Th) 1 (interleukin [IL]-12, IL-2, and interferon-γ [IFN-γ]) and Th2 (IL-4, IL-5, and IL-13) cytokines in MS in the high-risk Asian Indian population...
Association of high sensitivity C-reactive protein (hsCRP) and tumour necrosis factor-alpha (TNF-alpha) with carotid intimal medial thickness in subjects with different grades of glucose intolerance--the Chennai Urban Rural Epidemiology Study (CURES-31)Kuppan Gokulakrishnan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai, India
Clin Biochem 41:480-5. 2008..To assess the association of high sensitivity C-Reactive Protein [hsCRP] and Tumour Necrosis Factor-alpha [TNF-alpha] with IMT in Asian Indians with different grades of glucose intolerance...
Association of carotid intima-media thickness and arterial stiffness with diabetic retinopathy: the Chennai Urban Rural Epidemiology Study (CURES-2)Mohan Rema
M V Diabetes Specialties Centre and Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Diabetes Care 27:1962-7. 2004..The aim of this study was to assess the association of intima-media thickness (IMT) and arterial stiffness with diabetic retinopathy in an Asian-Indian population that has very high prevalence rates of diabetes and coronary artery disease...
Effect of filarial infection on serum inflammatory and atherogenic biomarkers in coronary artery disease (CURES-121)Vivekanandhan Aravindhan
Laboratory of Molecular Immunology, AU KBC Research Centre, Anna University, Chennai, India
Am J Trop Med Hyg 86:828-33. 2012..In conclusion, unlike type-2 diabetes, there is no association between the prevalence of LF and CAD and also no evidence of protective immunomodulation of LF infection on CAD in the Asian Indian population...
Circulating levels of insulin-like growth factor binding protein-1 in relation to insulin resistance, type 2 diabetes mellitus, and metabolic syndrome (Chennai Urban Rural Epidemiology Study 118)Kuppan Gokulakrishnan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, IDF Centre for Education, Gopalapuram, Chennai, India
Metabolism 61:43-6. 2012..942; 95% confidence interval, 0.914-0.971; P < .001). Among Asian Indians, lower levels of circulating IGFBP-1 are seen in subjects with IR, T2DM, and MS...
A novel association of a polymorphism in the first intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian IndiansKarani S Vimaleswaran
Madras Diabetes Research Foundation, Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Diabetes and ICMR Advanced Centre for Genomics of Diabetes, Chennai, India
Hum Genet 123:599-605. 2008..007) and TG (P = 0.001) genotypes compared to TT genotype. Among Asian Indians there is an association of +10211T-->G polymorphism in the first intron of the adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia...
Subclinical inflammation/oxidation as revealed by altered gene expression profiles in subjects with impaired glucose tolerance and Type 2 diabetes patientsKuppan Gokulakrishnan
Department of Cell and Molecular Biology, Madras Diabetes Research Foundation and, Dr Mohan s Diabetes Specialities Centre, 4, Conran Smith Road, Gopalapuram, Chennai, 600 086, India
Mol Cell Biochem 324:173-81. 2009..70, P < 0.01; TNF-alpha: beta = 1.86, P < 0.01). Increased subclinical inflammation/oxidation is seen in Asian Indians with not only Type 2 diabetes but also IGT...
Gallic acid protects RINm5F beta-cells from glucolipotoxicity by its antiapoptotic and insulin-secretagogue actionsZaheer Sameermahmood
Department of Cell and Molecular Biology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India 600086
Phytother Res 24:S83-94. 2010..It is suggested that the insulin-secretagogue and transcriptional regulatory action of gallic acid is a newly identified mechanism in our study...
Glutamine fructose-6-phosphate amidotransferase (GFAT) gene expression and activity in patients with type 2 diabetes: inter-relationships with hyperglycaemia and oxidative stressVedantham Srinivasan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialties Center 6B, Conran Smith Road, Gopalapuram, Chennai, India
Clin Biochem 40:952-7. 2007..However, there are very few clinical studies and none on Asian Indians, a high-risk group for type 2 diabetes (T2DM), which examined the role of GFAT in insulin resistance and T2DM...
Prevalence and risk factors of diabetic nephropathy in an urban South Indian population: the Chennai Urban Rural Epidemiology Study (CURES 45)Ranjit I Unnikrishnan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, 4 Conran Smith Rd, Gopalapuram, Chennai, 600 086, India
Diabetes Care 30:2019-24. 2007..The aim of this study was to determine the prevalence of diabetic nephropathy among urban Asian-Indian type 2 diabetic subjects...
Evidence for an association with type 2 diabetes mellitus at the PPARG locus in a South Indian populationKarani S Vimaleswaran
Madras Diabetes Research Foundation, Gopalapuram, Chennai 600 086, India Dr Mohan s Diabetes Specialities Centre, Chennai 600 086, India
Metabolism 59:457-62. 2010....
Decreased serum interleukin-17 and increased transforming growth factor-β levels in subjects with metabolic syndrome (Chennai Urban Rural Epidemiology Study-95)Jayagopi Surendar
Madras Diabetes Research Foundation, Chennai 600086, India
Metabolism 60:586-90. 2011..We report that IL-17 levels are decreased, whereas TGF-β levels are increased, among Asian Indians with MS...
Transcriptional regulation of cytokines and oxidative stress by gallic acid in human THP-1 monocytesGokulakrishnan Kuppan
Madras Diabetes Research Foundation and Dr Mohans Diabetes Specialities Centre, Gopalapuram, Chennai 600 086, India
Cytokine 49:229-34. 2010..Gallic acid beneficially modulate transcription of functionally diverse groups of genes and its regulation of SOCS-3 and TXNIP signals is a newly identified mechanism that has therapeutic implications...
Soluble P-selectin and CD40L levels in subjects with prediabetes, diabetes mellitus, and metabolic syndrome--the Chennai Urban Rural Epidemiology StudyKuppan Gokulakrishnan
Dr Mohans M V Diabetes Specialities Centre and Madras Diabetes Research Foundation, Gopalapuram, Chennai 600 086, India
Metabolism 55:237-42. 2006..05). This study demonstrates that increased levels of sP-selectin and sCD40L are seen in Asian Indian subjects with IGT, type 2 diabetes mellitus, MS, and insulin resistance...
Angiopoietin-2 levels in glucose intolerance, hypertension, and metabolic syndrome in Asian Indians (Chennai Urban Rural Epidemiology Study-74)Sathish Anuradha
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, Gopalapuram, Chennai 600086, India
Metabolism 59:774-9. 2010..001). This study demonstrates that increased levels of Ang-2 are seen in Asian Indian subjects with IGT, T2DM, and hypertension and in subjects with MS even in the absence of fasting hyperglycemia...
Association of the PPARGC1A gene polymorphism with diabetic nephropathy in an Asian Indian population (CURES-41)Sakthi Baby Gayathri
Madras Diabetes Research Foundation, and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Noncommunicable Diseases Prevention Control, Gopalapuram, Chennai, India
Metab Syndr Relat Disord 8:119-26. 2010....
Convergence of prevalence rates of diabetes and cardiometabolic risk factors in middle and low income groups in urban India: 10-year follow-up of the Chennai Urban Population StudyMohan Deepa
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Noncommunicable Diseases Prevention and Control, IDF Centre for Education, Chennai, India
J Diabetes Sci Technol 5:918-27. 2011..The aim of this study was to look for temporal changes in the prevalence of diabetes and cardiometabolic risk factors in two residential colonies in Chennai...
Indian Diabetes Risk Score helps to distinguish type 2 from non-type 2 diabetes mellitus (GDRC-3)Kunal M Sharma
Global Diabetes Research Center, Chennai, India
J Diabetes Sci Technol 5:419-25. 2011..The aim of this study was to investigate whether the Indian Diabetes Risk Score (IDRS) could assist in classifying type 2 diabetes mellitus (T2DM) and non-T2DM among patients attending clinics in India...
Association of visceral and subcutaneous fat with glucose intolerance, insulin resistance, adipocytokines and inflammatory markers in Asian Indians (CURES-113)Karunakaran Indulekha
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, International Diabetes Federation IDF Centre for Education, Gopalapuram, Chennai 600086, India
Clin Biochem 44:281-7. 2011..The aim of the study was to assess the association between visceral and subcutaneous fat with glucose intolerance, adipocytokines, inflammatory markers and carotid IMT in Asian Indians...
Comparison of carotid intima-media thickness, arterial stiffness, and brachial artery flow mediated dilatation in diabetic and nondiabetic subjects (The Chennai Urban Population Study [CUPS-9])Radhakrishnan Ravikumar
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Am J Cardiol 90:702-7. 2002..Diabetic patients have decreased FMD and increased arterial stiffness compared with age- and sex-matched nondiabetic subjects. These functional changes correlate well with the structural changes of the arteries measured by IMT...
Effectiveness of sitagliptin in asian Indian patients with type 2 diabetes-an Indian tertiary diabetes care center experienceChidambarann Sudhakaran
Dr Mohan s Diabetes Specialities Centre and Madras Diabetes Research Foundation, WHO Collaborating Centre for Non communicable Diseases and International Diabetes Federation Centre of Education, Gopalapuram, Chennai, India
Diabetes Technol Ther 13:27-32. 2011....
Prevalence of depression in relation to glucose intolerance in urban south Indians--the Chennai Urban Rural Epidemiology Study (CURES-76)Subramani Poongothai
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, International Diabetes Federation Centre of Education, Gopalapuram, Chennai, India
Diabetes Technol Ther 12:989-94. 2010..This study investigated the association between depression and glucose intolerance in urban residents of southern India...
Serum visfatin in relation to visceral fat, obesity, and type 2 diabetes mellitus in Asian IndiansSreedharan Sandeep
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai 600 086, India
Metabolism 56:565-70. 2007..Although visfatin levels are increased in type 2 diabetes mellitus, the association seems to be primarily through obesity...
Prevalence of diabetic retinopathy in urban India: the Chennai Urban Rural Epidemiology Study (CURES) eye study, IMohan Rema
Madras Diabetes Research Foundation, Chennai, India
Invest Ophthalmol Vis Sci 46:2328-33. 2005..To assess the prevalence of diabetic retinopathy (DR) in type 2 diabetic subjects in urban India using four-field stereo color photography...
Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathyAntonysunil Adaikalakoteswari
Department of Cell and Molecular Biology, Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, 4, Conran Smith Road, Gopalapuram, Chennai 600 086, India
Atherosclerosis 195:83-9. 2007..e., impaired glucose tolerance (IGT) and (2) whether telomere shortening was greater in Type 2 diabetic subjects with atherosclerotic plaques...
Role of continuous subcutaneous insulin infusion in patients with recalcitrant diabetes in South IndiaChidambarann Sudhakaran
Dr Mohan s Diabetes Specialities Centre and Madras Diabetes Research Foundation, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, Chennai, India
Diabetes Technol Ther 11:733-7. 2009....
A prevalent amino acid polymorphism at codon 98 (Ala98Val) of the hepatocyte nuclear factor-1alpha is associated with maturity-onset diabetes of the young and younger age at onset of type 2 diabetes in Asian IndiansShekher Anuradha
Dr Mohans MV Diabetes Specialties Centre and Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Diabetes Care 28:2430-5. 2005..The aim of this study was to estimate the prevalence of Ala98Val polymorphism of the HNF1alpha gene in different types of diabetes in Asian Indians...
The rs12255372(G/T) and rs7903146(C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian IndiansDhanasekaran Bodhini
MDRF ICMR Advanced Centre for Genomics of Diabetes, Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Metabolism 56:1174-8. 2007..6 +/- 1.0 mmol/L, P = .004). In conclusion, the T allele of the rs12255372(G/T) and rs7903146(C/T) polymorphisms of TCF7L2 gene confer susceptibility to type 2 diabetes mellitus in Asian Indians...
Glycaemic index of Indian flatbreads (rotis) prepared using whole wheat flour and 'atta mix'-added whole wheat flourGanesan Radhika
Madras Diabetes Research Foundation, Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non Communicable diseases, International Diabetes Federation IDF Centre of Education, 4, Conran Smith Road, Gopalapuram, Chennai, India
Br J Nutr 103:1642-7. 2010..5), P < 0.001). Development of foods with lower dietary glycaemic load such as the atta mix roti could help in the prevention and control of diabetes in South Asian populations, which habitually consume very high glycaemic load diets...
Decreased prevalence of lymphatic filariasis among diabetic subjects associated with a diminished pro-inflammatory cytokine response (CURES 83)Vivekanandhan Aravindhan
Madras Diabetes Research Foundation, Chennai, India
PLoS Negl Trop Dis 4:e707. 2010....
Prevalence of diabetic complications in fibrocalculous pancreatic diabetic patients and type 2 diabetic patients: a cross-sectional comparative studyKaruna Kanta Barman
Madras Diabetes Research Foundation, Conran Smith Road, Gopalapuram, Chennai 600086, India
J Diabetes Complications 18:264-70. 2004..011) and BMI (P=.010) with neuropathy. Conclusion: The prevalence of retinopathy, nephropathy, neuropathy, and PVD was similar among FCPD patients and type 2 diabetic patients, but the prevalence of CAD was lower among FCPD patients...
Visceral and central abdominal fat and anthropometry in relation to diabetes in Asian IndiansMohan Anjana
Diabetes Specialities Centre and Madras Diabetes Research Foundation, 4 Conran Smith Rd, Gopalapuram, Chennai 600 086, India
Diabetes Care 27:2948-53. 2004..CONCLUSIONS: Visceral and central abdominal fat showed a strong association with type 2 diabetes. Both measures correlated well with each other and with waist circumference and SAD in diabetic and nondiabetic urban Asian Indians...
Association of physical inactivity with components of metabolic syndrome and coronary artery disease--the Chennai Urban Population Study (CUPS no. 15)V Mohan
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Diabet Med 22:1206-11. 2005..The aim of the study was to assess the influence of physical activity on the components of metabolic syndrome (MS) in an urban south Indian population in Chennai...
Intra-urban differences in the prevalence of the metabolic syndrome in southern India -- the Chennai Urban Population Study (CUPS No. 4)V Mohan
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Diabet Med 18:280-7. 2001..To assess the influence of socioeconomic status on the prevalence of the metabolic syndrome in an urban south Indian population in Chennai...
Prevalence and significance of generalized and central body obesity in an urban Asian Indian population in Chennai, India (CURES: 47)M Deepa
Madras Diabetes Research Foundation, Dr Mohan s Diabetes Specialities Centre, Chennai, India
Eur J Clin Nutr 63:259-67. 2009..To determine the prevalence of generalized and abdominal obesity in urban Asian Indians and compare the association of body mass index (BMI) and waist circumference (WC) with metabolic risk variables...
Intimal media thickness, glucose intolerance and metabolic syndrome in Asian Indians--the Chennai Urban Rural Epidemiology Study (CURES -22)V Mohan
Dr Mohan s Diabetes Specialities Centre and Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Diabet Med 23:845-50. 2006..The aim of the present study was to assess carotid intimal media thickness (IMT) in different grades of glucose intolerance and the metabolic syndrome (MS) in Asian Indians, a high-risk group for diabetes and coronary artery disease...
Association of lipoprotein lipase gene polymorphisms with obesity and type 2 diabetes in an Asian Indian populationV Radha
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Int J Obes (Lond) 31:913-8. 2007....
Prevalence and risk factors for diabetic neuropathy in an urban south Indian population: the Chennai Urban Rural Epidemiology Study (CURES-55)R Pradeepa
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai, India
Diabet Med 25:407-12. 2008..This study was conducted to determine the prevalence of, and risk factors for, diabetic neuropathy (DN) in south Indian Type 2 diabetic subjects...
Lipoprotein(a) is an independent risk factor for coronary artery disease in NIDDM patients in South IndiaV Mohan
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Diabetes Care 21:1819-23. 1998..The objective of this study was to assess the role of Lp(a) as a marker for CAD in South Indian NIDDM patients...
Association of serum lipids with diabetic retinopathy in urban South Indians--the Chennai Urban Rural Epidemiology Study (CURES) Eye Study--2M Rema
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai, India
Diabet Med 23:1029-36. 2006..To study the association of serum lipids with diabetic retinopathy (DR) in Type 2 diabetic subjects...
The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian IndiansD Bodhini
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai, India
Int J Obes (Lond) 31:97-102. 2007..To investigate the association of insulin receptor substrate-2 (IRS-2) G1057D polymorphism with type 2 diabetes and obesity in Asian Indians...
Glucose intolerance (diabetes and IGT) in a selected South Indian population with special reference to family history, obesity and lifestyle factors--the Chennai Urban Population Study (CUPS 14)V Mohan
MV Diabetes Specialities Centre and Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
J Assoc Physicians India 51:771-7. 2003..Lifestyle factors and family history have a synergistic effect on increasing the risk for diabetes in this population...
A diabetes risk score helps identify metabolic syndrome and cardiovascular risk in Indians - the Chennai Urban Rural Epidemiology Study (CURES-38)V Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Chennai, Tamil Nadu, India
Diabetes Obes Metab 9:337-43. 2007....
Telomere shortening occurs in Asian Indian Type 2 diabetic patientsA Adaikalakoteswari
Department of Cell and Molecular Biology, Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Diabet Med 22:1151-6. 2005..Multiple linear regression (MLR) analysis revealed diabetes to be significantly (P < 0.0001) associated with shortening of TRF lengths. CONCLUSIONS: Telomere shortening occurs in Asian Indian Type 2 diabetic patients...
Association of small dense LDL with coronary artery disease and diabetes in urban Asian Indians - the Chennai Urban Rural Epidemiology Study (CURES-8)V Mohan
Dr. Mohans' M.V. Diabetes Specialities Centre, Gopalapuram, Chennai, India
J Assoc Physicians India 53:95-100. 2005..CONCLUSION: This data suggests that in Asian Indians, small dense LDL is associated with both diabetes and CAD and that a triglycerides/HDL ratio (3.0 could serve a surrogate marker of small dense LDL...
Association of C-reactive protein with body fat, diabetes and coronary artery disease in Asian Indians: the Chennai Urban Rural Epidemiology Study (CURES-6)V Mohan
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Diabet Med 22:863-70. 2005..The aim of the study was to determine the association of high sensitivity C-reactive protein (hs-CRP) with body fat, diabetes and coronary artery disease (CAD) in an urban south Indian population...
Serum levels of interleukin 6, C-reactive protein, vascular cell adhesion molecule 1, and monocyte chemotactic protein 1 in relation to insulin resistance and glucose intolerance--the Chennai Urban Rural Epidemiology Study (CURES)Raj Deepa
Madras Diabetes Research Foundation and Dr. Mohan's Diabetes Specialities Centre, Gopalapuram, Chennai 600 086, India
Metabolism 55:1232-8. 2006..158; P = .028). In conclusion, this study shows that in Asian Indians, inflammatory markers (CRP, IL-6, and VCAM-1) increase with increasing degrees of glucose intolerance...
Mortality rates due to diabetes in a selected urban south Indian population--the Chennai Urban Population Study [CUPS--16]V Mohan
Diabetes Specialities Centre and Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
J Assoc Physicians India 54:113-7. 2006..CONCLUSIONS: In urban India, mortality rates are two fold higher in people with diabetes compared to nondiabetic subjects. Cardiovascular and renal diseases are the commonest causes of death among diabetic subjects...
Prevalence of metabolic syndrome using WHO, ATPIII and IDF definitions in Asian Indians: the Chennai Urban Rural Epidemiology Study (CURES-34)M Deepa
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Diabetes Metab Res Rev 23:127-34. 2007....
Prevalence of non-alcoholic fatty liver disease in urban south Indians in relation to different grades of glucose intolerance and metabolic syndromeV Mohan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai, India
Diabetes Res Clin Pract 84:84-91. 2009..To estimate prevalence of non-alcoholic fatty liver disease (NAFLD) and its association with glucose intolerance (type 2 diabetes (DM), prediabetes) and metabolic syndrome (MS) in urban south Indians...
Adiponectin and carotid intimal medial thickness in subjects with and without glucose intolerance (CURES-82)K Gokulakrishnan
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, WHO Collaborating Centre for Non communicable Diseases Prevention and Control, Gopalapuram, Chennai, India
Diabetes Technol Ther 12:109-15. 2010..This study assessed the association of serum adiponectin with carotid intimal medial thickness (IMT) in Asian Indians with different grades of glucose intolerance...
Prevalence of insulin resistance syndrome in a selected south Indian population--the Chennai urban population study-7 [CUPS-7]R Deepa
Madras Diabetes Research Foundation, Chennai, India
Indian J Med Res 115:118-27. 2002..INTERPRETATION & CONCLUSION: The overall prevalence rate of IRS was 11.2 per cent. Age and higher socio-economic status were the risk factors for insulin resistance in this selected urban south Indian study population...
Association of hypertension with cluster of insulin resistance syndrome factors: the Chennai Urban Population Study (CUPS-12)R Deepa
Madras Diabetes Research Foundation, 4 Conran Smith Road, Gopalapuram, 600 086, Chennai, India
Acta Diabetol 41:49-55. 2004..Our results suggest that the "insulin resistance cluster" is associated with hypertension in this urban population of southern India...
The Chennai Urban Rural Epidemiology Study (CURES)--study design and methodology (urban component) (CURES-I)M Deepa
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
J Assoc Physicians India 51:863-70. 2003..CURES is perhaps one of the largest systematic population based studies to be done in India in the field of diabetes and its complications like retinopathy, nephropathy and neuropathy...
Relationship of lipoprotein(a) with intimal medial thickness of the carotid artery in Type 2 diabetic patients in south IndiaK Velmurugan
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
Diabet Med 20:455-61. 2003..032) and Lp(a) (P = 0.021) to be associated with carotid atherosclerosis. CONCLUSION: The results suggest that Lp(a) has a strong association with IMT of carotid arteries in Type 2 diabetic subjects in south India...
Prevalence and risk factors of hypertension in a selected South Indian population--the Chennai Urban Population StudyC S Shanthirani
Madras Diabetes Research Foundation, Gopalapuram, Chennai, India
J Assoc Physicians India 51:20-7. 2003..001), body mass index (p < 0.001) and glucose intolerance (p = 0.005). CONCLUSION: The prevalence of hypertension appears to be high in this urban South Indian population and this calls for urgent steps for its prevention and control...
The changing scenario of the diabetes epidemic: implications for IndiaR Pradeepa
Madras Diabetes Research Foundation and M.V. Diabetes Specialities Centre, Chennai, India
Indian J Med Res 116:121-32. 2002....
Cystatin C and cystatin glomerular filtration rate as markers of early renal disease in Asian Indian subjects with glucose intolerance (CURES-32)J Surendar
Madras Diabetes Research Foundation, Kallam Anji Reddy Centre, Siruseri, India
Metab Syndr Relat Disord 7:419-25. 2009..The aim of this study was to assess cystatin C (cys-C) as a marker of early diabetic nephropathy and cystatin glomerular filtration rate (cys-GFR) in Asian Indians...
Surveillance for risk factors of cardiovascular disease among an industrial population in southern IndiaV Mohan
Madras Diabetes Research Foundation, 4, Conran Smith Road, Gopalapuram, Chennai 600086, Tamil Nadu, India
Natl Med J India 21:8-13. 2008....
Risk factors for diabetic retinopathy in a South Indian Type 2 diabetic population--the Chennai Urban Rural Epidemiology Study (CURES) Eye Study 4R Pradeepa
Madras Diabetes Research Foundation and Dr Mohan s Diabetes Specialities Centre, Gopalapuram, Chennai, India
Diabet Med 25:536-42. 2008..To determine risk factors for diabetic retinopathy (DR) in an urban South Indian Type 2 diabetic population...
Macrovascular component of diabetes atherosclerosis and insulin (CUPS-18)V Mohan
Madras Diabetes Research Foundation, India
J Assoc Physicians India 55:13-8. 2007
