Vijay Luxami

Summary

Country: India

Publications

  1. doi request reprint Pyrophosphate selective fluorescent probe and molecular flip-flop
    Vijay Luxami
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Dalton Trans 42:3783-6. 2013
  2. ncbi request reprint FRET-based ratiometric detection of Hg2+ and biothiols using naphthalimide-rhodamine dyads
    Vijay Luxami
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Org Biomol Chem 10:8076-81. 2012
  3. ncbi request reprint A differential ICT based molecular probe for multi-ions and multifunction logic circuits
    Vijay Luxami
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Dalton Trans 41:4588-93. 2012
  4. doi request reprint Synthesis, in vitro antitumor activity, dihydrofolate reductase inhibition, DNA intercalation and structure-activity relationship studies of 1,3,5-triazine analogues
    Prinka Singla
    School of Chemistry and Biochemistry, Thapar University, Patiala 147001, India
    Bioorg Med Chem Lett 26:518-23. 2016
  5. doi request reprint Triazine as a promising scaffold for its versatile biological behavior
    Prinka Singla
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Eur J Med Chem 102:39-57. 2015
  6. doi request reprint Benzimidazole-Based Quinazolines: In Vitro Evaluation, Quantitative Structure-Activity Relationship, and Molecular Modeling as Aurora Kinase Inhibitors
    Alka Sharma
    School of Chemistry and Biochemistry, Thapar University, Patiala, India
    Arch Pharm (Weinheim) 349:193-201. 2016
  7. doi request reprint Purine-benzimidazole hybrids: synthesis, single crystal determination and in vitro evaluation of antitumor activities
    Alka Sharma
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Eur J Med Chem 93:414-22. 2015
  8. doi request reprint Ratiometric fluorescent chemosensor for fluoride ion based on inhibition of excited state intramolecular proton transfer
    Akul Sen Gupta
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Spectrochim Acta A Mol Biomol Spectrosc 138:67-72. 2015
  9. doi request reprint Triazine-benzimidazole hybrids: anticancer activity, DNA interaction and dihydrofolate reductase inhibitors
    Prinka Singla
    School of Chemistry and Biochemistry, Thapar University, Patiala 147001, India
    Bioorg Med Chem 23:1691-700. 2015
  10. doi request reprint Recent advances in development of imidazo[1,2-a]pyrazines: synthesis, reactivity and their biological applications
    Richa Goel
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Org Biomol Chem 13:3525-55. 2015

Collaborators

  • Subodh Kumar
  • Kamaldeep Paul
  • Prinka Singla
  • Alka Sharma
  • Akul Sen Gupta
  • Richa Goel
  • Meenakshi Verma
  • Sanjai Saxena

Detail Information

Publications12

  1. doi request reprint Pyrophosphate selective fluorescent probe and molecular flip-flop
    Vijay Luxami
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Dalton Trans 42:3783-6. 2013
    ..The implementation of the first molecule based JK-latch sequential logic function is also described...
  2. ncbi request reprint FRET-based ratiometric detection of Hg2+ and biothiols using naphthalimide-rhodamine dyads
    Vijay Luxami
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Org Biomol Chem 10:8076-81. 2012
    ..The interconversion of probe and via the complexation/decomplexation by the modulation of Hg(2+)/Cys exhibited a selective probe for biothiols in real samples...
  3. ncbi request reprint A differential ICT based molecular probe for multi-ions and multifunction logic circuits
    Vijay Luxami
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Dalton Trans 41:4588-93. 2012
    ..This single molecule behaves uniquely where different logic functions can be operated and reset by using different inputs and outputs...
  4. doi request reprint Synthesis, in vitro antitumor activity, dihydrofolate reductase inhibition, DNA intercalation and structure-activity relationship studies of 1,3,5-triazine analogues
    Prinka Singla
    School of Chemistry and Biochemistry, Thapar University, Patiala 147001, India
    Bioorg Med Chem Lett 26:518-23. 2016
    ..0nM. DNA binding studies were also revealed strong interacting properties of triazine derivatives towards calf thymus-DNA. ..
  5. doi request reprint Triazine as a promising scaffold for its versatile biological behavior
    Prinka Singla
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Eur J Med Chem 102:39-57. 2015
    ....
  6. doi request reprint Benzimidazole-Based Quinazolines: In Vitro Evaluation, Quantitative Structure-Activity Relationship, and Molecular Modeling as Aurora Kinase Inhibitors
    Alka Sharma
    School of Chemistry and Biochemistry, Thapar University, Patiala, India
    Arch Pharm (Weinheim) 349:193-201. 2016
    ..The current study identifies a novel class of Aurora kinase inhibitors, which can further be used for the treatment of cancer. ..
  7. doi request reprint Purine-benzimidazole hybrids: synthesis, single crystal determination and in vitro evaluation of antitumor activities
    Alka Sharma
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Eur J Med Chem 93:414-22. 2015
    ..Compound 6 showed selectivity towards Aurora-A kinase inhibition with IC50 value of 0.0l μM. Molecular docking studies in the active binding site provided theoretical support for the experimental biological data acquired. ..
  8. doi request reprint Ratiometric fluorescent chemosensor for fluoride ion based on inhibition of excited state intramolecular proton transfer
    Akul Sen Gupta
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Spectrochim Acta A Mol Biomol Spectrosc 138:67-72. 2015
    ..The probe 2 showed fluorescence behavior towards fluoride ions through hydrogen bonding interactions and restricted the ESIPT emission at 540nm from OH to nitrogen of benzimidazole moiety to release its enol emission at 420nm. ..
  9. doi request reprint Triazine-benzimidazole hybrids: anticancer activity, DNA interaction and dihydrofolate reductase inhibitors
    Prinka Singla
    School of Chemistry and Biochemistry, Thapar University, Patiala 147001, India
    Bioorg Med Chem 23:1691-700. 2015
    ..Compound 6b was depicted as the most active member of DHFR inhibitor with IC50 value of 1.05μM. Molecular modelling studies were used to identify the stabilized interactions of Compound 6b within the active site of enzyme for DHFR. ..
  10. doi request reprint Recent advances in development of imidazo[1,2-a]pyrazines: synthesis, reactivity and their biological applications
    Richa Goel
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India
    Org Biomol Chem 13:3525-55. 2015
    ..This review is mainly based on the pattern and position of the substitution, and should help the scientific community to bring about future developments. ..
  11. doi request reprint Synthesis and in vitro antitumor evaluation of primary amine substituted quinazoline linked benzimidazole
    Kamaldeep Paul
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India Electronic address
    Bioorg Med Chem Lett 24:624-9. 2014
    ..In vitro evaluation of compound 11 exhibited remarkable anticancer activity towards colon cancer cell lines and prostate cancer cell lines at five dose concentrations with GI50 values of 0.34 and 0.31 μM, respectively...
  12. doi request reprint Synthesis, in vitro evaluation and molecular modelling of naphthalimide analogue as anticancer agents
    Meenakshi Verma
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, Punjab, India
    Eur J Med Chem 68:352-60. 2013
    ..ct-DNA binding studies of most active compound 5d revealed strong interacting properties. Molecular docking studies in the active binding site provided complementary theoretical support for the experimental biological data acquired. ..