Ashok Kumar

Summary

Country: India

Publications

  1. doi request reprint Quick PCR based diagnosis of typhoid using specific genetic markers
    Ashok Kumar
    Institute of Genomics and Integrative Biology, Mall Road, Delhi, 110007, India
    Biotechnol Lett 32:707-12. 2010
  2. ncbi request reprint sof gene as a specific genetic marker for detection of Streptococcus pyogenes causing pharyngitis and rheumatic heart disease
    A Kumar
    Institute of Genomics and Integrative Biology, Delhi, India
    Cell Mol Biol (Noisy-le-grand) 57:26-30. 2011
  3. ncbi request reprint Leukemia in infants
    Saika Somjee
    Department of Medical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
    Indian J Pediatr 69:225-7. 2002
  4. doi request reprint Free radical injury and blood-brain barrier permeability in hypoxic-ischemic encephalopathy
    Ashok Kumar
    Banaras Hindu University, Division of Neonatology, Department of Pediatrics, Institute of Medical Sciences, Varanasi 221005, India
    Pediatrics 122:e722-7. 2008
  5. doi request reprint Accidentally falling instruments during orthopaedic surgery: time to wake up!
    Shah A Khan
    Department of Orthopaedics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    ANZ J Surg 78:794-5. 2008
  6. doi request reprint Structural elucidation of process-related impurities in escitalopram by LC/ESI-MS and NMR
    Bhanu Raman
    Department of Chemistry, K J Somaiya College of Science and Commerce, Vidyavihar E, Mumbai, India
    J Pharm Biomed Anal 53:895-901. 2010
  7. doi request reprint An unusual cause of meconium peritonitis in a foetus
    Sriparna Basu
    Division of Neonatology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    J Paediatr Child Health 45:231-3. 2009
  8. doi request reprint Semi-preparative isolation and structural elucidation of an impurity in citalopram by LC/MS/MS
    Bhanu Raman
    Department of Chemistry, K J Somaiya College of Science and Commerce, Vidyavihar E, Mumbai 400077, India
    J Pharm Biomed Anal 50:377-83. 2009
  9. doi request reprint Evidences showing association of interleukin-1B polymorphisms with increased risk of gastric cancer in an Indian population
    Sushil Kumar
    School of Biotechnology, Banaras Hindu University, Varanasi, India
    Biochem Biophys Res Commun 387:456-60. 2009
  10. pmc Functional and radiological outcome after delayed fixation of femoral neck fractures in pediatric patients
    Manish Kumar Varshney
    All India Institute of Medical Sciences, New Delhi, India
    J Orthop Traumatol 10:211-6. 2009

Collaborators

Detail Information

Publications35

  1. doi request reprint Quick PCR based diagnosis of typhoid using specific genetic markers
    Ashok Kumar
    Institute of Genomics and Integrative Biology, Mall Road, Delhi, 110007, India
    Biotechnol Lett 32:707-12. 2010
    ..The sensitivity of the method is up to 5 fg genomic DNA. The genetic markers are specific and the four pairs of primers give selective amplification and differentiate S. typhi from closely related S. typhimurium...
  2. ncbi request reprint sof gene as a specific genetic marker for detection of Streptococcus pyogenes causing pharyngitis and rheumatic heart disease
    A Kumar
    Institute of Genomics and Integrative Biology, Delhi, India
    Cell Mol Biol (Noisy-le-grand) 57:26-30. 2011
    ..Amplicon of 228 bp of sof gene does not show homology with other organisms and can be used as genetic marker for S. pyogenes...
  3. ncbi request reprint Leukemia in infants
    Saika Somjee
    Department of Medical Oncology, Tata Memorial Hospital, Parel, Mumbai, India
    Indian J Pediatr 69:225-7. 2002
    ..It is characterized by non-specific symptomatology requiring a high index of suspicion on the part of a pediatrician for referral and diagnosis. It has peculiar biological features, unresponsiveness to treatment and poor prognosis...
  4. doi request reprint Free radical injury and blood-brain barrier permeability in hypoxic-ischemic encephalopathy
    Ashok Kumar
    Banaras Hindu University, Division of Neonatology, Department of Pediatrics, Institute of Medical Sciences, Varanasi 221005, India
    Pediatrics 122:e722-7. 2008
    ....
  5. doi request reprint Accidentally falling instruments during orthopaedic surgery: time to wake up!
    Shah A Khan
    Department of Orthopaedics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    ANZ J Surg 78:794-5. 2008
    ..The aim of the study was to evaluate statistically the occurrence and causes of accidental fall of instruments and implants during orthopaedic procedures...
  6. doi request reprint Structural elucidation of process-related impurities in escitalopram by LC/ESI-MS and NMR
    Bhanu Raman
    Department of Chemistry, K J Somaiya College of Science and Commerce, Vidyavihar E, Mumbai, India
    J Pharm Biomed Anal 53:895-901. 2010
    ..The impurities were isolated by semi-preparative HPLC and structures were confirmed by NMR spectroscopy. The plausible mechanism for the formation of impurities is also discussed...
  7. doi request reprint An unusual cause of meconium peritonitis in a foetus
    Sriparna Basu
    Division of Neonatology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    J Paediatr Child Health 45:231-3. 2009
    ..Role of an intestinal mucus plug as the potential factor for intestinal obstruction and subsequent perforation has been highlighted in the present case...
  8. doi request reprint Semi-preparative isolation and structural elucidation of an impurity in citalopram by LC/MS/MS
    Bhanu Raman
    Department of Chemistry, K J Somaiya College of Science and Commerce, Vidyavihar E, Mumbai 400077, India
    J Pharm Biomed Anal 50:377-83. 2009
    ..The impurity was isolated by semi-preparative HPLC. The structure of the impurity was confirmed as 1-(1,1-bis (4-fluorophenyl)-1,3-dihydroisobenzofuran-5-yl)-4-(dimethylamino) butan-1-one hydrobromide by using NMR and IR spectroscopy...
  9. doi request reprint Evidences showing association of interleukin-1B polymorphisms with increased risk of gastric cancer in an Indian population
    Sushil Kumar
    School of Biotechnology, Banaras Hindu University, Varanasi, India
    Biochem Biophys Res Commun 387:456-60. 2009
    ..pylori infection markedly increases the risk of GC in North Indian population. Additionally, IL-1B-511 C/C and IL-RN 2/2 polymorphisms seem to be involved in the development of GC in H. pylori uninfected patients...
  10. pmc Functional and radiological outcome after delayed fixation of femoral neck fractures in pediatric patients
    Manish Kumar Varshney
    All India Institute of Medical Sciences, New Delhi, India
    J Orthop Traumatol 10:211-6. 2009
    ..Also, the role of capsular decompression in initial management needs to be elucidated...
  11. ncbi request reprint Endoprosthetic replacement for giant cell tumour of the proximal femur
    Shah Alam Khan
    Department of Orthopaedics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    J Orthop Surg (Hong Kong) 17:280-3. 2009
    ..To evaluate the functional and oncological outcomes of 12 patients with giant cell tumour (GCT) of the proximal femur treated with customized endoprosthesis...
  12. doi request reprint Structural elucidation of a process-related impurity in ezetimibe by LC/MS/MS and NMR
    Bhanu Raman
    Department of Chemistry, K J Somaiya College of Science and Commerce, Vidyavihar E, Mumbai 400077, India
    J Pharm Biomed Anal 52:73-8. 2010
    ..The chemical shift of the labile proton of that new entity was assigned by a 2D-NOESY NMR experiment. A rationalization for the formation of this impurity is provided...
  13. doi request reprint Prevalence of three-rooted mandibular permanent first molars among the Indian Population
    Amit Kumar Garg
    Department of Conservative Dentistry and Endodontics, Dr Z A Dental College, Aligarh Muslim University, Aligarh 202002 U P, India
    J Endod 36:1302-6. 2010
    ..The aim of this retrospective study was to determine the prevalence of three-rooted mandibular permanent first molars among the Indian population by using periapical radiographs...
  14. ncbi request reprint Chemical composition and fungitoxic activity of essential oil of Thuja orientalis L. grown in the north-western Himalaya
    Sanjay Guleria
    Division of Biochemistry and Plant Physiology, Sher e Kashmir University of Agricultural Sciences and Technology, Faculty of Agriculture, Chatha, Jammu 180 009, India
    Z Naturforsch C 63:211-4. 2008
    ..5 microg, respectively, using a bioautography assay. The bioactive constituent corresponding to b1 was determined as alpha-cedrol by using GC/MS analysis. The potential of essential oils as a source of natural biocides is discussed...
  15. doi request reprint Low grade central osteosarcoma--a diagnostic dilemma
    Ashok Kumar
    Department of Orthopedics and Pathology, All India Institute of Medical Sciences, Ansari Nagar, Flat No 3221 Ground Floor, Sector A, PKT B and C, Vasant Kunj, New Delhi 110070, India
    Joint Bone Spine 75:613-5. 2008
    ..Three years later the tumor recurred with greater soft tissue and bony involvement but without metastasis. The patient was treated with above knee amputation and has been asymptomatic for the last two years...
  16. ncbi request reprint Evidences showing ultraviolet-B radiation-induced damage of DNA in cyanobacteria and its detection by PCR assay
    Ashok Kumar
    Microbial Biotechnology Unit, School of Biotechnology, Banaras Hindu University, Varanasi 221 005, India
    Biochem Biophys Res Commun 318:1025-30. 2004
    ..It is felt that PCR assay may be conveniently used for screening the damages caused to DNA by UV-B radiation in cyanobacteria and other microorganisms...
  17. ncbi request reprint Continuous maxillary and mandibular nerve block for perioperative pain relief: the excision of a complicated pleomorphic adenoma
    Ashok Kumar
    Department of Anaesthesiology and Critical Care, UCMS and GTB Hospital, Delhi, India
    Anesth Analg 101:1531-2. 2005
    ..Continuous maxillary and mandibular nerve blocks were performed and excision was performed with complete intraoperative and postoperative pain relief without compromising the patient's hemodynamic variables...
  18. ncbi request reprint Endodontic treatment of a maxillary first molar having three mesiobuccal canals with the aid of spiral computed tomography: a case report
    Amit K Garg
    Department of Conservative Dentistry and Endodontics, Dr Z A Dental College, Aligarh Muslim University, Aligarh, India
    J Oral Sci 52:495-9. 2010
    ..This unusual morphology was confirmed by spiral computed tomography (SCT). This article discusses the variations in canal morphology and the role of SCT in successfully diagnosing and negotiating them...
  19. ncbi request reprint External pancreatic fistula as a sequel to management of acute severe necrotizing pancreatitis
    Sadiq S Sikora
    Department of Surgical Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Dig Surg 22:446-51; discussion 452. 2005
    ..The present study was aimed at studying the clinical profile, course and outcome of patients with EPF following surgical or percutaneous management of these infective complications...
  20. ncbi request reprint Prednisolone in Duchenne muscular dystrophy with imminent loss of ambulation
    Sunil Pradhan
    Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, 226014, India
    J Neurol 253:1309-16. 2006
    ....
  21. ncbi request reprint Unusual presentation of isolated sacral tuberculosis
    Ashok Kumar
    Department of Orthopedics, All India Institute of Medical Sciences, New Delhi 110029, India
    Joint Bone Spine 73:751-2. 2006
    ..Early diagnosis and treatment can prevent or minimize the neurological morbidity in such cases...
  22. ncbi request reprint Role of steroids on the clinical course and outcome of meconium aspiration syndrome-a randomized controlled trial
    Sriparna Basu
    Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    J Trop Pediatr 53:331-7. 2007
    ..Meconium aspiration syndrome (MAS) is one of the major causes of severe respiratory distress in the newborn and there is no uniform protocol of management after the development of MAS...
  23. ncbi request reprint Role of antibiotics in meconium aspiration syndrome
    Sriparna Basu
    Division of Neonatology, Department of Paediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    Ann Trop Paediatr 27:107-13. 2007
    ..Meconium aspiration syndrome (MAS) is a major cause of severe respiratory distress in newborns and the role of antibiotics in its management is not well defined...
  24. ncbi request reprint Post-cholecystectomy biliary strictures: not always benign
    Ajay Sharma
    Department of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    J Gastroenterol Hepatol 23:e63-6. 2008
    ..Post-cholecystectomy malignant biliary obstruction masquerading as benign biliary stricture (BBS) has not been reported in the literature; it presents a diagnostic and management challenge...
  25. doi request reprint Congenital spinal tuberculosis associated with asymptomatic endometrial tuberculosis: A rare case report
    Ashok Kumar
    Department of Orthopaedics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
    Joint Bone Spine 75:353-5. 2008
    ..Endometrial biopsy help in establishing the diagnosis of congenital tuberculosis and adequate antitubercular treatment in such cases may provide protection to fetus in subsequent pregnancy...
  26. doi request reprint Kimura disease of extremity: unusual manifestation in a long bone
    Manish Kumar Varshney
    Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi 110029, India
    Joint Bone Spine 75:492-4. 2008
    ..We present an unusual case of long bone periosteal reaction in a patient of Kimura's disease of extremity. This potentially innocuous disorder must be kept in mind as a radiological differential of periosteal reaction...
  27. doi request reprint Ponseti's manipulation in neglected clubfoot in children more than 7 years of age: a prospective evaluation of 25 feet with long-term follow-up
    Shah Alam Khan
    Department of Orthopaedics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    J Pediatr Orthop B 19:385-9. 2010
    ..Recurrence was seen in six feet (24%). At 4-year follow-up, the average Dimeglio score for 19 feet was 0.18. We recommend that Ponseti's method should be the preferred initial treatment modality for neglected clubfeet...
  28. doi request reprint rmpM Genosensor for Detection of Human Brain Bacterial Meningitis in Cerebrospinal Fluid
    Sandip Kumar Dash
    CSIR Institute of Genomics and Integrative Biology, Mall Road, Delhi, 110007, India
    Appl Biochem Biotechnol 171:198-208. 2013
    ..The advantage of rmpM genosensor is to detect bacterial meningitis simultaneously in multiple patients using SPGE array during an outbreak of the disease. ..
  29. ncbi request reprint Role of HCV coinfection towards disease progression and survival in HIV-1 infected children: a follow-up study of 10 years
    Swami Onkar Shivraj
    Department of Statistics, University of Delhi, Delhi, India
    J Trop Pediatr 52:206-11. 2006
    ..39; 95 per cent CI:1.17-4.89; p<0.01). It appears that HCV infection may be an important contributor to the rapid disease progression and increase in mortality in HCV-HIV-1 coinfected children of thalassemia major...
  30. doi request reprint Omp85 genosensor for detection of human brain bacterial meningitis
    Sandip Kumar Dash
    CSIR Institute of Genomics and Integrative Biology, Mall Road, Delhi, 110007, India
    Biotechnol Lett 35:929-35. 2013
    ..954. The genosensor was characterized using Fourier transform infrared spectroscopy and atomic force microscopy. Omp85 genosensor was stable for 12 months at 4 °C with 12 % loss in DPV current...
  31. doi request reprint Engineered polymer-supported synthesis of 3'-carboxyalkyl-modified oligonucleotides and their applications in the construction of biochips for diagnosis of the diseases
    Satyakam Patnaik
    CSIR Institute of Genomics and Integrative Biology, Delhi University Campus, Mall Road, Delhi 110 007, India
    Bioconjug Chem 23:664-70. 2012
    ..The performance of these biochips was evaluated under different sets of conditions and then successfully validated by the detection of base mismatches and human infectious disease, bacterial meningitis, caused by N. meningitidis...
  32. doi request reprint Electrochemical DNA sensor for Neisseria meningitidis detection
    Manoj K Patel
    Institute of Genomics and Integrative Biology, Delhi, India
    Biosens Bioelectron 25:2586-91. 2010
    ..0115 microA/ng cm(-2) and 0.0056 microA/ng cm(-2), respectively with regression coefficient (R) as 0.999. This DNA bioelectrode is stable for about 4 months when stored at 4 degrees C...
  33. pmc EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda
    Shilpi Aggarwal
    Genomics and Molecular Medicine, Institute of Genomics and Integrative Biology, Council of Scientific and Industrial Research, New Delhi 110007, India
    Proc Natl Acad Sci U S A 107:18961-6. 2010
    ....
  34. ncbi request reprint A randomized trial of eutectic mixture of local anesthetics during lumbar puncture in newborns
    Geetinder Kaur
    Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India
    Arch Pediatr Adolesc Med 157:1065-70. 2003
    ..To determine the efficacy of a topical anesthetic cream, eutectic mixture of local anesthetics (EMLA), in alleviating pain associated with lumbar puncture in newborns...
  35. ncbi request reprint Delayed periprosthetic tuberculosis after total knee replacement: is conservative treatment possible?
    Devdatta Suhas Neogi
    Department of Orthopedic, All India Institute of Medical Sciences, Ansari Nagar, Delhi, India
    Acta Orthop Belg 75:136-40. 2009
    ..This shows that conservative treatment is possible when there is no loosening of the implant. However, surgical treatment is necessary in most cases and must be individualized...