International Centre for Genetic Engineering and Biotechnology

Summary

Organization: International Centre for Genetic Engineering and Biotechnology
Country: India

Top Publications

  1. pmc Molecular characterization of two distinct monopartite begomoviruses infecting tomato in India
    Prerna Pandey
    Plant Molecular Biology Group, International Centre for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi 110067, India
    Virol J 7:337. 2010
  2. doi Blood stage malaria antigens induce different activation-induced cell death programs in splenic CD4+T cells
    P Mukherjee
    International Centre of Genetic Engineering and Biotechnology, Aruna Asaf Ali Road, New Delhi, India
    Parasite Immunol 30:497-514. 2008
  3. pmc VirulentPred: a SVM based prediction method for virulent proteins in bacterial pathogens
    Aarti Garg
    Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi 110067, India
    BMC Bioinformatics 9:62. 2008
  4. ncbi Plasmodium falciparum signal peptidase is regulated by phosphorylation and required for intra-erythrocytic growth
    Renu Tuteja
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    Mol Biochem Parasitol 157:137-47. 2008
  5. ncbi Targeting the Plasmodium vivax Duffy-binding protein
    Chetan E Chitnis
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, New Delhi 110067, India
    Trends Parasitol 24:29-34. 2008
  6. ncbi Helicases - feasible antimalarial drug target for Plasmodium falciparum
    Renu Tuteja
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
    FEBS J 274:4699-704. 2007
  7. ncbi Malaria - an overview
    Renu Tuteja
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
    FEBS J 274:4670-9. 2007
  8. ncbi Enhancing salt tolerance in a crop plant by overexpression of glyoxalase II
    Sneh L Singla-Pareek
    Plant Molecular Biology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, 110 067, India
    Transgenic Res 17:171-80. 2008
  9. pmc An adenovirus prime/plasmid boost strategy for induction of equipotent immune responses to two dengue virus serotypes
    Saima Khanam
    RGP Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    BMC Biotechnol 7:10. 2007
  10. pmc ProtRepeatsDB: a database of amino acid repeats in genomes
    Mridul K Kalita
    Structural and Computational Biology Group, Malaria Group, International Centre for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi 110067, India
    BMC Bioinformatics 7:336. 2006

Scientific Experts

Detail Information

Publications62

  1. pmc Molecular characterization of two distinct monopartite begomoviruses infecting tomato in India
    Prerna Pandey
    Plant Molecular Biology Group, International Centre for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi 110067, India
    Virol J 7:337. 2010
    ..We describe here the genetic diversity of two isolates of monopartite Tomato leaf curl virus infecting tomato in two extreme regions (North and South) of Indian subcontinent...
  2. doi Blood stage malaria antigens induce different activation-induced cell death programs in splenic CD4+T cells
    P Mukherjee
    International Centre of Genetic Engineering and Biotechnology, Aruna Asaf Ali Road, New Delhi, India
    Parasite Immunol 30:497-514. 2008
    ..These results provide insights into the mechanism through which two blood stage merozoite antigens trigger different apoptotic programs of AICD in splenic CD4(+) T cells...
  3. pmc VirulentPred: a SVM based prediction method for virulent proteins in bacterial pathogens
    Aarti Garg
    Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi 110067, India
    BMC Bioinformatics 9:62. 2008
    ....
  4. ncbi Plasmodium falciparum signal peptidase is regulated by phosphorylation and required for intra-erythrocytic growth
    Renu Tuteja
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    Mol Biochem Parasitol 157:137-47. 2008
    ..These studies demonstrate the characterization of a functional subunit of SPC from P. falciparum and should make an important contribution in our better understanding of the complex process of protein translocation in the parasite...
  5. ncbi Targeting the Plasmodium vivax Duffy-binding protein
    Chetan E Chitnis
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, New Delhi 110067, India
    Trends Parasitol 24:29-34. 2008
    ..Here, we review data on the interaction of PvRII with DARC and explore the potential of targeting this crucial receptor-ligand interaction to develop new intervention strategies against P. vivax...
  6. ncbi Helicases - feasible antimalarial drug target for Plasmodium falciparum
    Renu Tuteja
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
    FEBS J 274:4699-704. 2007
    ..One feasible target might be helicases, which are important unwinding enzymes and required for almost all the nucleic acid metabolism in the malaria parasite...
  7. ncbi Malaria - an overview
    Renu Tuteja
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
    FEBS J 274:4670-9. 2007
    ....
  8. ncbi Enhancing salt tolerance in a crop plant by overexpression of glyoxalase II
    Sneh L Singla-Pareek
    Plant Molecular Biology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, 110 067, India
    Transgenic Res 17:171-80. 2008
    ..Compared with non-transgenics, transgenic plants at the T1 generation exhibited sustained growth and more favorable ion balance under salt stress conditions...
  9. pmc An adenovirus prime/plasmid boost strategy for induction of equipotent immune responses to two dengue virus serotypes
    Saima Khanam
    RGP Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    BMC Biotechnol 7:10. 2007
    ....
  10. pmc ProtRepeatsDB: a database of amino acid repeats in genomes
    Mridul K Kalita
    Structural and Computational Biology Group, Malaria Group, International Centre for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi 110067, India
    BMC Bioinformatics 7:336. 2006
    ..icgeb.res.in/repeats/ is a relational database of perfect and mismatch repeats, access to which is designed as a resource and collection of tools for detection and cross species comparisons of different types of amino acid repeats...
  11. ncbi Improvement in yield and purity of a recombinant malaria vaccine candidate based on the receptor-binding domain of Plasmodium vivax Duffy binding protein by codon optimization
    Syed Shams Yazdani
    Malaria Research Group, International Centre for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi, India
    Biotechnol Lett 28:1109-14. 2006
    ..Expression level of recombinant PvRII was 10% of the total cellular proteins. Truncated PvRII products, seen when the native PvRII gene was expressed, were absent in case of synthetic gene...
  12. ncbi Unraveling the 'DEAD-box' helicases of Plasmodium falciparum
    Renu Tuteja
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, P O Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India
    Gene 376:1-12. 2006
    ..These detailed studies may help to identify a parasite-specific enzyme, which could be a potential drug target to treat malaria. The various steps at which this probable drug can act are also discussed...
  13. pmc Transgenic tobacco overexpressing glyoxalase pathway enzymes grow and set viable seeds in zinc-spiked soils
    Sneh L Singla-Pareek
    Plant Molecular Biology, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110 067, India
    Plant Physiol 140:613-23. 2006
    ....
  14. ncbi Type I signal peptidase: an overview
    Renu Tuteja
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    Arch Biochem Biophys 441:107-11. 2005
    ..Type I signal peptidases have been found in bacteria, archaea, fungi, plants, and animals. In this review, I present an overview of bacterial type I signal peptidases and describe some of their properties in detail...
  15. doi Genotoxic stress in plants: shedding light on DNA damage, repair and DNA repair helicases
    Narendra Tuteja
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    Mutat Res 681:134-49. 2009
    ..This article describes the insight underlying the DNA damage and repair pathways in plants. The comet assay to measure the DNA damage and the role of DNA repair helicases such as XPD and XPB are also covered...
  16. pmc Analysis of small nucleolar RNAs reveals unique genetic features in malaria parasites
    Prakash Chandra Mishra
    Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology Aruna Asaf Ali Road, New Delhi, 110067, India
    BMC Genomics 10:68. 2009
    ..In vertebrates, most snoRNAs are present in introns of protein coding genes and are processed by exonucleolytic cleavage, while in plants they are transcribed as polycistronic transcripts...
  17. ncbi Dengue: recent advances in biology and current status of translational research
    Sathyamangalam Swaminathan
    Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, P O Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India
    Curr Mol Med 9:152-73. 2009
    ..Dengue research is at a critical juncture and the implementation of existing knowledge supplemented by a better understanding of pathogenesis promises to make a tangible impact in the combat against dengue in the coming years...
  18. pmc Tomato leaf curl Kerala virus (ToLCKeV) AC3 protein forms a higher order oligomer and enhances ATPase activity of replication initiator protein (Rep/AC1)
    Kalyan K Pasumarthy
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    Virol J 7:128. 2010
    ..ToLCKeV, a virus prevalent in the tomato crop of Kerala state of India and a member of genus Begomovirus has been used as a model system in this study...
  19. pmc Conserved thioredoxin fold is present in Pisum sativum L. sieve element occlusion-1 protein
    Narendra Tuteja
    International Centre for Genetic Engineering and Biotechnology Aruna Asaf Ali Marg, New Delhi, India
    Plant Signal Behav 5:623-8. 2010
    ..Motif 1 (EVF) is conserved in Ps.SEO1, Vicia faba (Vf.For1) and Medicago truncatula (Mt.SEO3); motif 2 (KKED) is well conserved across all forisomes proteins and motif 3 (IGYIGNP) is conserved in Ps.SEO1 and Vf.For1...
  20. doi Dengue vaccines: state of the art
    Sathyamangalam Swaminathan
    International Centre for Genetic Engineering and Biotechnology, Recombinant Gene Products Group, PO Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India
    Expert Opin Ther Pat 20:819-35. 2010
    ..Dengue is a significant public health problem transcending geographical boundaries to place nearly 50% of the global population at risk. A vaccine to prevent dengue is an unmet need that should be addressed urgently...
  21. ncbi Adenovirus-vectored vaccines
    Tanu Chawla
    International Centre for Genetic Engineering and Biotechnology, Recombinant Gene Products Group, PO Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India 91 11 2674 2357 ext 271 91 11 2674 2316
    Expert Opin Ther Pat 18:293-307. 2008
    ..This has spurred intensive efforts to find alternative adenovirus vectors and strategies, each with its own advantages and shortcomings...
  22. pmc A genomic glimpse of aminoacyl-tRNA synthetases in malaria parasite Plasmodium falciparum
    Tarun Kumar Bhatt
    Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
    BMC Genomics 10:644. 2009
    ..Aminoacyl-tRNA synthetases (aaRSs) are pivotal enzymes for protein translation and other vital cellular processes. We report an extensive analysis of the Plasmodium falciparum genome to identify and classify aaRSs in this organism...
  23. pmc LipocalinPred: a SVM-based method for prediction of lipocalins
    Jayashree Ramana
    Bioinformatics Laboratory, Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    BMC Bioinformatics 10:445. 2009
    ..This is particularly true for protein families sharing extremely low sequence identity, as for lipocalins, a family of proteins with varied functions and great diversity at the sequence level, yet conserved structures...
  24. ncbi Genome wide identification of Plasmodium falciparum helicases: a comparison with human host
    Renu Tuteja
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    Cell Cycle 9:104-20. 2010
    ..falciparum. The detailed studies of these helicases will help in identifying a specific enzyme, which could be used as potential target to control the replication and transmission of the malaria parasite...
  25. doi Forisomes: calcium-powered protein complexes with potential as 'smart' biomaterials
    Narendra Tuteja
    Plant Molecular Biology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    Trends Biotechnol 28:102-10. 2010
    ..Forisome-based 'smart' materials can be used to produce self-powered monitoring and diagnostic systems. Here, we focus on physiological, chemical and physical aspects of forisomes and discuss their potential as biomimetic devices...
  26. pmc Signaling through G protein coupled receptors
    Narendra Tuteja
    Plant Molecular Biology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    Plant Signal Behav 4:942-7. 2009
    ..Here I have described a general mechanism of signal transduction through GPCR/G proteins, structure of GPCRs, family of GPCRs and plant GPCR and its role...
  27. pmc Heparan sulfate proteoglycans are required for cellular binding of the hepatitis E virus ORF2 capsid protein and for viral infection
    Manjula Kalia
    Virology Research Group, International Centre for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi 110 067, India
    J Virol 83:12714-24. 2009
    ..Our results indicate that, analogous to some enveloped viruses, a nonenveloped virus like HEV may have also evolved to use HSPGs as cellular attachment receptors...
  28. doi Isolation and functional characterization of eIF4F components and poly(A)-binding protein from Plasmodium falciparum
    Renu Tuteja
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    Parasitol Int 58:481-5. 2009
    ..These studies demonstrate that these factors are structurally and functionally conserved. These studies will contribute to understand the important process and components of translation complex in the malaria parasite...
  29. pmc A systematic classification of Plasmodium falciparum P-loop NTPases: structural and functional correlation
    Deepti Gangwar
    Malaria Group, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    Malar J 8:69. 2009
    ..A number of characteristic attributes of the genome have resulted into the lack of knowledge about this functionally diverse, but important class of proteins...
  30. pmc Structural insights into chondroitin sulphate A binding Duffy-binding-like domains from Plasmodium falciparum: implications for intervention strategies against placental malaria
    Jasmita Gill
    Structural and Computational Biology Group, International Centre for Genetic Engineering and Biotechnology ICGEB, New Delhi, India
    Malar J 8:67. 2009
    ..Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) encoded by the var2CSA gene is believed to be the main parasite ligand for CSA-mediated placental binding...
  31. pmc Comparison of immunogenicities of recombinant Plasmodium vivax merozoite surface protein 1 19- and 42-kiloDalton fragments expressed in Escherichia coli
    Suraksha Sachdeva
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    Infect Immun 72:5775-82. 2004
    ..These findings may have implications for the design of MSP-1-based vaccine constructs...
  32. ncbi Serial analysis of gene expression (SAGE): unraveling the bioinformatics tools
    Renu Tuteja
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    Bioessays 26:916-22. 2004
    ..In this review, we present an outline of the method, various bioinformatics methods for data analysis and general applications of this important technology...
  33. ncbi Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum
    Pawan Malhotra
    International Centre for Genetic Engineering and Biotechnology, PPO Box 10504, Aruna Asaf Ali Marg, New Delhi 110 065, India
    Mol Microbiol 45:1245-54. 2002
    ..falciparum and also suggest possibilities for using RNAi as an effective tool to determine the functions of the genes identified from the P. falciparum genome sequencing project...
  34. ncbi Chemoprotection profiles of sodium thiosulfate on methyl methanesulfonate-induced mutagenesis of bacteriophage T4
    Ajmaluddin Malik
    Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, India
    Med Sci Monit 8:BR212-20. 2002
    ..Sodium thiosulfate (STS), used as a chemoprotectant, has been tested against alkylating drugs...
  35. ncbi A new approach for efficient directional genome walking using polymerase chain reaction
    M K Reddy
    International Centre for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi, India
    Anal Biochem 306:154-8. 2002
  36. ncbi DNA vaccine against malaria: a long way to go
    Renu Tuteja
    International Centre for Genetic Engineering and Biotechnology, New Delhi
    Crit Rev Biochem Mol Biol 37:29-54. 2002
    ..This review presents an update of the studies carried out in malaria using DNA vaccine approach, the challenges, and the future prospects...
  37. ncbi Molecular diversity of the plasmid genotypes among Rhizobium gene pools of sesbanias from different habitats of a semi-arid region (Delhi)
    A Mohmmed
    Department of Botany, University of Delhi, India
    FEMS Microbiol Lett 205:171-8. 2001
    ..We suggest that habitat heterogeneity and plasticity of plasmid genotype together contribute for the generation of genetic diversity leading to strainal differentiation in rhizobia...
  38. ncbi Molecular mechanisms of DNA damage and repair: progress in plants
    N Tuteja
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    Crit Rev Biochem Mol Biol 36:337-97. 2001
    ....
  39. ncbi Molecular insights into receptors used by malaria parasites for erythrocyte invasion
    C E Chitnis
    Malaria Research Group, International Center for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi, India
    Curr Opin Hematol 8:85-91. 2001
    ..Clear understanding of these interactions is important for the rational design of vaccines that attempt to inhibit invasion and prevent malaria...
  40. ncbi Cloning and expression of a nuclear encoded plastid specific 33 kDa ribonucleoprotein gene (33RNP) from pea that is light stimulated
    M K Reddy
    International Centre for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, New Delhi 110 067, India
    Gene 263:179-87. 2001
    ..Sequence analysis of the genomic clone revealed that the gene contains four exons and three introns. We have also isolated and analyzed the 5' flanking region of the pea 33RNP gene...
  41. ncbi A pea homologue of human DNA helicase I is localized within the dense fibrillar component of the nucleolus and stimulated by phosphorylation with CK2 and cdc2 protein kinases
    N Tuteja
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110 070, India
    Plant J 25:9-17. 2001
    ..These observations suggest that PDH65 may be involved both in rDNA transcription and in the early stages of pre-rRNA processing...
  42. ncbi Augmentation of immune responses to hepatitis E virus ORF2 DNA vaccination by codelivery of cytokine genes
    R Tuteja
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    Viral Immunol 13:169-78. 2000
    ..We further show that the immune responses generated by plasmid pcDNA-ORF2 can be boosted with virus-like particles composed of the ORF2 protein expressed through a baculovirus expression system...
  43. ncbi Ku autoantigen: a multifunctional DNA-binding protein
    R Tuteja
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi
    Crit Rev Biochem Mol Biol 35:1-33. 2000
    ..The mechanism underlying the regulation of all the diverse functions of Ku is still obscure...
  44. ncbi Inorganic phosphate regulates CryIVA protoxin expression in Bacillus thuringiensis israelensis
    N Banerjee-Bhatnagar
    International Center for Genetic Engineering and Biotechnology, New Delhi, 110067, India
    Biochem Biophys Res Commun 262:359-64. 1999
    ..The efficiency of sporulation of Bti was not affected when Pi was added alone or along with the phosphatase inhibitor calyculin A...
  45. ncbi The X gene of hepatitis B virus shows a high level stimulation of the Rous sarcoma virus long terminal repeat in the methylotropic yeast, Pichia pastoris
    S K Lal
    Virology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    FEBS Lett 456:108-12. 1999
    ..Therefore, unlike the transactivation studies with X gene in animal cells where limited functional activity is observed, P. pastoris appears to be an excellent system to study cis- and trans-aspects of gene regulation by the X gene...
  46. ncbi Isolation and characterization of an eIF-4A homologue from Plasmodium cynomolgi
    Renu Tuteja
    International Center for Genetic Engineering and Biotechnology, PO Box 10504, Aruna Asaf Ali Marg, New Delhi, India
    Mol Biochem Parasitol 124:79-83. 2002
  47. ncbi Specific and instantaneous one-step chemodetection of histidine-rich proteins by Pauly's stain
    Dinkar Sahal
    Malaria Lab, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
    Anal Biochem 308:405-8. 2002
  48. ncbi Global amplification of cDNA from limiting amounts of tissue. An improved method for gene cloning and analysis
    M K Reddy
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110 067, India
    Mol Biotechnol 22:223-30. 2002
    ..RACE-PCR done with biotinylated primers and streptavidin-coated para-magnetic particles are used for the efficient isolation of either full-length coding or noncoding strands...
  49. ncbi Serial analysis of gene expression (SAGE): application in cancer research
    Renu Tuteja
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    Med Sci Monit 10:RA132-40. 2004
    ..In this review we present an outline of the method and updated information on the applications of SAGE technology to various cancers...
  50. ncbi Unraveling DNA helicases. Motif, structure, mechanism and function
    Narendra Tuteja
    International Centre for Genetic Engineering and Biotechnology ICGEB, New Delhi, India
    Eur J Biochem 271:1849-63. 2004
    ..The genes containing helicase motifs may have evolved from a common ancestor. In this review we cover the conserved motifs, structural information, mechanism of DNA unwinding and translocation, and functional aspects of DNA helicases...
  51. ncbi Prokaryotic and eukaryotic DNA helicases. Essential molecular motor proteins for cellular machinery
    Narendra Tuteja
    International Centre for Genetic Engineering and Biotechnology ICGEB, New Delhi, India
    Eur J Biochem 271:1835-48. 2004
    ..The properties of most of the known DNA helicases from prokaryotic and eukaryotic systems, including viruses and bacteriophages, are summarized in tables...
  52. ncbi Genetically decaffeinated coffee
    Shahid Jameel
    International Centre for Genetic Engineering and Biotechnology, New Delhi 110 067, India
    J Biosci 28:529-31. 2003
  53. ncbi Plant DNA helicases: the long unwinding road
    Narendra Tuteja
    Plant Molecular Biology, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    J Exp Bot 54:2201-14. 2003
    ..In this review, an up-to-date knowledge of plant DNA helicases is summarized. In addition, the historical perspective, biochemical assay and polarity, inhibitors and functions of plant DNA helicases have also been covered...
  54. ncbi Current status of malaria vaccine development
    Virander Singh Chauhan
    Malaria Research Group, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    Adv Biochem Eng Biotechnol 84:143-82. 2003
    ..Latest developments in the field of malaria vaccine development will be discussed in this chapter...
  55. pmc Pea DNA topoisomerase I is phosphorylated and stimulated by casein kinase 2 and protein kinase C
    Narendra Tuteja
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, P O Box 10504, New Delhi 110 067, India
    Plant Physiol 132:2108-15. 2003
    ..This study shows that these kinases may contribute to the physiological regulation of DNA topoisomerase I activity and overall DNA metabolism in plants...
  56. ncbi Replication fork-stimulated eIF-4A from Plasmodium cynomolgi unwinds DNA in the 3' to 5' direction and is inhibited by DNA-interacting compounds
    Renu Tuteja
    International Centre for Genetic Engineering and Biotechnology, P O Box 10504, Aruna Asaf Ali Marg, New Delhi 110067, India
    Arch Biochem Biophys 414:108-14. 2003
    ....
  57. ncbi Synthetic propeptide inhibits mosquito midgut chitinase and blocks sporogonic development of malaria parasite
    Raj K Bhatnagar
    International Center for Genetic Engineering and Biotechnology ICGEB, Aruna Asaf Ali Marg, P O Box 10504, New Delhi 1100 67, India
    Biochem Biophys Res Commun 304:783-7. 2003
    ..This may lead to developing novel strategies for controlling the spread of malaria...
  58. ncbi Down-regulation of T helper 1 responses to mycobacterial antigens due to maturation of dendritic cells by 10-kDa mycobacterium tuberculosis secretory antigen
    Krishnamurthy Natarajan
    Immunology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    J Infect Dis 187:914-28. 2003
    ....
  59. ncbi Structure of a gametocyte protein essential for sexual development in Plasmodium falciparum
    Amit Sharma
    Malaria Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India
    Nat Struct Biol 10:197-203. 2003
    ..The structural and initial biochemical evidence suggests that Pfg27 may serve as a platform for RNA and SH3 binding...
  60. ncbi Applying malaria parasite's heme detoxification system for screening potential antimalarial drugs
    Dinkar Sahal
    International Center for Genetic Engineering and Biotechnology, New Delhi 110 067, India
    Anal Biochem 312:258-60. 2003
  61. ncbi Purification and diagnostic utility of a recombinant hepatitis E virus capsid protein expressed in insect larvae
    Deepak Sehgal
    Virology Group, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110 067, India
    Protein Expr Purif 27:27-34. 2003
    ..Antigen expression in the insect larvae system presents a rapid and low-cost method that obviates the need for expensive tissue culture scale-ups or special equipment...
  62. ncbi DNA vaccines: a ray of hope
    R Tuteja
    Immunology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi, India
    Crit Rev Biochem Mol Biol 34:1-24. 1999
    ..These include the technical challenges of improving delivery and/or potency so that low doses of DNA can achieve the efficacy of conventional vaccines...