Research Topics
| Dinesh DhingraSummaryCountry: India Publications
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Publications
Ascorbic Acid: a promising memory-enhancer in miceMilind Parle
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University, Haryana, India
J Pharmacol Sci 93:129-35. 2003..Hence, ascorbic acid might prove to be a useful memory-restorative agent in the treatment of dementia seen in elderly individuals. The underlying mechanism of action of ascorbic acid may be attributed to its antioxidant property...
Antidepressant-like activity of n-hexane extract of nutmeg (Myristica fragrans) seeds in miceDinesh Dhingra
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University, Hisar, Haryana, India
J Med Food 9:84-9. 2006..The antidepressant-like effect of the extract seems to be mediated by interaction with the adrenergic, dopaminergic, and serotonergic systems...
Antidepressant-like activity of ellagic acid in unstressed and acute immobilization-induced stressed miceDinesh Dhingra
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, Haryana, India
Pharmacol Rep 64:796-807. 2012..On the other hand, antidepressant-like activity of ellagic acid in stressed mice might be through inhibition of inducible NOS...
Possible involvement of monoaminergic neurotransmission in antidepressant-like activity of Emblica officinalis fruits in miceDinesh Dhingra
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Haryana, India
CNS Neurosci Ther 18:419-25. 2012..In this study, antidepressant-like activity of Emblica offcinalis Gaertn. fruits (Family: Euphorbiaceae) was evaluated in Swiss young male albino mice employing tail suspension test and forced swim test...
Antianxiety-like activity of gallic acid in unstressed and stressed mice: possible involvement of nitriergic systemDinesh Dhingra
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, Haryana 125001, India
Neurochem Res 37:487-94. 2012..On the other hand, antianxiety-like activity in stressed mice might be through inhibition of iNOS and reduction of plasma corticosterone levels...
Inhibition of MAO and GABA: probable mechanisms for antidepressant-like activity of Nardostachys jatamansi DC. in miceDinesh Dhingra
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125 001, India
Indian J Exp Biol 46:212-8. 2008..Thus, the extract may have potential therapeutic value for the management of mental depression...
Evaluation of antidepressant-like activity of aqueous and ethanolic extracts of Terminalia bellirica Roxb. fruits in miceDinesh Dhingra
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125 001, India
Indian J Exp Biol 45:610-6. 2007..Thus, both the aqueous and ethanolic extracts of T. bellirica elicited a significant antidepressant-like effect in mice by interaction with adrenergic, dopaminergic and serotonergic systems...
Evaluation of the antidepressant-like activity of Convolvulus pluricaulis choisy in the mouse forced swim and tail suspension testsDinesh Dhingra
Department of Pharmaceutical Sciences, Pharmacology Division, Guru Jambheshwar University of Science and Technology, Hisar, India
Med Sci Monit 13:BR155-61. 2007..This study investigates the effect of the petroleum ether, chloroform, and ethyl acetate fractions of the total ethanolic extract of Convolvulus pluricaulis Choisy (Family: Convolvulaceae) on depression in mice...
Comparative brain cholinesterase-inhibiting activity of Glycyrrhiza glabra, Myristica fragrans, ascorbic acid, and metrifonate in miceDinesh Dhingra
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, India
J Med Food 9:281-3. 2006..Acetylcholinesterase enzyme was estimated in brains of mice. G. glabra, M. fragrans, ascorbic acid, and metrifonate significantly decreased acetylcholinesterase activity as compared with their respective vehicle-treated control groups...
Antidepressant-like activity of Glycyrrhiza glabra L. in mouse models of immobility testsDinesh Dhingra
Pharmacology Division, Department Pharmaceutical Sciences, Guru Jambheshwar University, Hisar 125001 Haryana, India
Prog Neuropsychopharmacol Biol Psychiatry 30:449-54. 2006..Monoamine oxidase inhibiting effect of liquorice may be contributing favorably to the antidepressant-like activity. Thus, it is concluded that liquorice extract may possess an antidepressant-like effect...
Memory-strengthening activity of Glycyrrhiza glabra in exteroceptive and interoceptive behavioral modelsMilind Parle
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University, Hisar, Haryana, India
J Med Food 7:462-6. 2004..However, further studies are necessitated to identify the exact mechanism of action. In the present investigation, G. glabra has shown promise as a memory enhancer in both exteroceptive and interoceptive behavioral models of memory...
Memory enhancing activity of Glycyrrhiza glabra in miceDinesh Dhingra
Pharmacology Division, Department of Pharmaceutical Sciences, P O Box 38, Guru Jambheshwar University, Hisar 125001, Haryana, India
J Ethnopharmacol 91:361-5. 2004..However, further studies are necessitated to identify the exact mechanism of action. In the present investigation, Glycyrrhiza glabra has shown promise as a memory enhancing agent in all the laboratory models employed...
Improvement of mouse memory by Myristica fragrans seedsMilind Parle
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University, Hisar 125001, Haryana, India
J Med Food 7:157-61. 2004..But, the observed memory-enhancing effect may be attributed to a variety of properties (individually or in combination) the plant is reported to possess, such as antioxidant, anti-inflammatory, or perhaps procholinergic activity...
Differential effects of nitric oxide synthase inhibitors on anxiety in unstressed and stressed miceNeeraj Gilhotr
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125 001, India
Indian J Exp Biol 48:365-72. 2010..The results suggest the possible role of inducible nitric oxide synthase in stress-induced anxiogenesis as compared to unstressed mice, where neuronal form of NOS may plays predominant role...
GABAergic and nitriergic modulation by curcumin for its antianxiety-like activity in miceNeeraj Gilhotra
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, India
Brain Res 1352:167-75. 2010..These findings suggest the possible involvement of only inducible NOS and not neuronal NOS in antianxiety-like effect of curcumin...
Thymoquinone produced antianxiety-like effects in mice through modulation of GABA and NO levelsNeeraj Gilhotra
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, Haryana, India
Pharmacol Rep 63:660-9. 2011..Therefore, the present study suggests an involvement of NO-cGMP and GABAergic pathways in the anxiolytic-like activity of thymoquinone...
Involvement of NO-cGMP pathway in anti-anxiety effect of aminoguanidine in stressed miceNeeraj Gilhotra
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, 125001, Haryana, India
Prog Neuropsychopharmacol Biol Psychiatry 33:1502-7. 2009..Thus, aminoguanidine produced anti-anxiety activity in stressed mice through iNOS-NO-cGMP pathway...
Hypolipidemic and weight reducing activity of the ethanolic extract of Tamarindus indica fruit pulp in cafeteria diet- and sulpiride-induced obese ratsVaneeta Jindal
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125 001, India
J Pharmacol Pharmacother 2:80-4. 2011..To investigate the effect of ethanolic extract of fruit pulp of Tamarindus indica Linn. (Family: Caesalpiniaceae) on obesity in rats using cafeteria diet-induced obesity and antipsychotic drug (sulpiride)-induced obesity...
