Gagandeep Kang

Summary

Affiliation: Christian Medical College
Country: India

Publications

  1. ncbi request reprint Molecular epidemiology of rotaviral infection in South Indian children with acute diarrhea from 1995-1996 to 1998-1999
    Gagandeep Kang
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore, Tamilnadu, India
    J Med Virol 67:101-5. 2002
  2. ncbi request reprint Appropriate technology for rural India - solar decontamination of water for emergency settings and small communities
    Gagandeep Kang
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamilnadu, India
    Trans R Soc Trop Med Hyg 100:863-6. 2006
  3. pmc Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India
    Dheepa Muthusamy
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, 632004, India
    J Clin Microbiol 44:632-4. 2006
  4. pmc Neonatal infection with G10P[11] rotavirus did not confer protection against subsequent rotavirus infection in a community cohort in Vellore, South India
    Indrani Banerjee
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632 004, India
    J Infect Dis 195:625-32. 2007
  5. pmc Human stool contains a previously unrecognized diversity of novel astroviruses
    Stacy R Finkbeiner
    Department of Molecular Microbiology and Pathology, Washington University School of Medicine, St Louis, MO, USA
    Virol J 6:161. 2009
  6. pmc Chronic growth faltering amongst a birth cohort of Indian children begins prior to weaning and is highly prevalent at three years of age
    Andrea M Rehman
    MRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    Nutr J 8:44. 2009
  7. pmc Rotavirus vaccines
    G Kang
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamilnadu, India
    Indian J Med Microbiol 24:252-7. 2006
  8. pmc Epidemiological profile of rotaviral infection in India: challenges for the 21st century
    Gagandeep Kang
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Infect Dis 192:S120-6. 2005
  9. ncbi request reprint Community prevalence of antibodies to human immunodeficiency virus in rural and urban Vellore, Tamil Nadu
    Gagandeep Kang
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu 632004, India
    Natl Med J India 18:15-7. 2005
  10. pmc Quantitation of group A rotavirus by real-time reverse-transcription-polymerase chain reaction: correlation with clinical severity in children in South India
    Gagandeep Kang
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore, India
    J Med Virol 73:118-22. 2004

Research Grants

Detail Information

Publications94

  1. ncbi request reprint Molecular epidemiology of rotaviral infection in South Indian children with acute diarrhea from 1995-1996 to 1998-1999
    Gagandeep Kang
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore, Tamilnadu, India
    J Med Virol 67:101-5. 2002
    ....
  2. ncbi request reprint Appropriate technology for rural India - solar decontamination of water for emergency settings and small communities
    Gagandeep Kang
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamilnadu, India
    Trans R Soc Trop Med Hyg 100:863-6. 2006
    ..It would be effective in the decrease and prevention of waterborne disease in emergency situations, and is appropriate for use in small communities...
  3. pmc Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India
    Dheepa Muthusamy
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, 632004, India
    J Clin Microbiol 44:632-4. 2006
    ..meleagridis were identified. Cpgp40/15 PCR-restriction fragment length polymorphism identified six subgenotypes. Cryptosporidial diarrhea was associated with decreased CD4 counts, below 200 (P = 0.009), but not high viral loads...
  4. pmc Neonatal infection with G10P[11] rotavirus did not confer protection against subsequent rotavirus infection in a community cohort in Vellore, South India
    Indrani Banerjee
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632 004, India
    J Infect Dis 195:625-32. 2007
    ..We examined the incidence of rotavirus infection and diarrhea during the first 2 years of life among children infected with the G10P[11] rotavirus strain during the neonatal period and those not infected with rotavirus...
  5. pmc Human stool contains a previously unrecognized diversity of novel astroviruses
    Stacy R Finkbeiner
    Department of Molecular Microbiology and Pathology, Washington University School of Medicine, St Louis, MO, USA
    Virol J 6:161. 2009
    ..Given that a significant fraction of diarrhea etiologies is currently unknown, it is plausible that these or other yet unrecognized astroviruses may be responsible for at least part of the undiagnosed cases...
  6. pmc Chronic growth faltering amongst a birth cohort of Indian children begins prior to weaning and is highly prevalent at three years of age
    Andrea M Rehman
    MRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    Nutr J 8:44. 2009
    ..We describe growth up to three years of age and investigate factors related to stunting (low height-for-age) at three years of age in a birth cohort from an urban slum...
  7. pmc Rotavirus vaccines
    G Kang
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamilnadu, India
    Indian J Med Microbiol 24:252-7. 2006
    ..In addition to completing clinical evaluations of vaccines in development in settings with the highest disease burden and virus diversity, there is also a need to consider alternative vaccine development strategies...
  8. pmc Epidemiological profile of rotaviral infection in India: challenges for the 21st century
    Gagandeep Kang
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Infect Dis 192:S120-6. 2005
    ..In India, the diversity of rotaviruses reported during the 1980s and 1990s emphasizes the need for surveillance of cocirculating strains, to follow the rapid changes in circulation and to detect novel strains...
  9. ncbi request reprint Community prevalence of antibodies to human immunodeficiency virus in rural and urban Vellore, Tamil Nadu
    Gagandeep Kang
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu 632004, India
    Natl Med J India 18:15-7. 2005
    ..The association between antenatal and community prevalence of HIV needs to be validated so that estimates can be verified or adjusted appropriately...
  10. pmc Quantitation of group A rotavirus by real-time reverse-transcription-polymerase chain reaction: correlation with clinical severity in children in South India
    Gagandeep Kang
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore, India
    J Med Virol 73:118-22. 2004
    ..80, P < 0.001) between severity and the PCR cycle at which the PCR amplicons were detectable (crossing point) on the assay, indicating that children with more severe diarrhoea excrete more virus than children with less severe disease...
  11. ncbi request reprint Etiology of diarrhea in patients undergoing allogeneic bone marrow transplantation in South India
    Gagandeep Kang
    Department of Gastrointestinal Sciences and Haematology, Christian Medical College and Hospital, Vellore 632004, India
    Transplantation 73:1247-51. 2002
    ..No studies so far have examined enteric infections in patients undergoing bone marrow transplantation (BMT) in developing countries where asymptomatic carriage and colonization with enteric pathogens is frequent...
  12. ncbi request reprint Distribution of rotavirus G and P types in north and south Indian children with acute diarrhoea in 1998-99
    G Kang
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore 632004, India
    Trans R Soc Trop Med Hyg 95:491-2. 2001
    ..Overall, 68/82 (83%) could be VP7- and 52/82 (63%) VP4-typed. Geographical differences in rotavirus circulation have implications for future vaccination strategies...
  13. ncbi request reprint A monkey model for enterohemorrhagic Escherichia coli infection
    G Kang
    Wellcome Trust Laboratory, Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore, India
    J Infect Dis 184:206-10. 2001
    ..This monkey model closely parallels the early stages of the disease produced by E. coli O157:H7 and would be useful in the further study of pathogenic mechanisms and prevention methods in enterohemorrhagic E. coli infections...
  14. ncbi request reprint Enteroaggregative Escherichia coli infection in a rabbit model
    G Kang
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore, India
    Pathology 33:341-6. 2001
    ..Bacteria were seen in intercellular spaces and within M cells, a finding that has not previously been described. It is clearly possible to produce gut colonisation by oral infection with EAEC in adult rabbits with normal flora...
  15. pmc Molecular characterization of G11P[25] and G3P[3] human rotavirus strains associated with asymptomatic infection in South India
    Indrani Banerjee
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Med Virol 79:1768-74. 2007
    ....
  16. pmc Genogroup IIb norovirus infections and association with enteric symptoms in a neonatal nursery in southern India
    Vipin Kumar Menon
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, India
    J Clin Microbiol 48:3212-5. 2010
    ..The study demonstrates a high prevalence of NoV infections in neonates and indicates that coinfection with rotavirus may result in significantly more gastrointestinal disease in this population...
  17. pmc Multisite study of cryptosporidiosis in children with diarrhea in India
    Sitara Swarna Rao Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, India
    J Clin Microbiol 48:2075-81. 2010
    ..A novel C. parvum subgenotype, IIn, was identified in Vellore. Meteorological analysis revealed a higher rate of cryptosporidial positivity during hotter and drier weather in Delhi...
  18. doi request reprint Severity of rotavirus gastroenteritis in Indian children requiring hospitalization
    Thuppal V Sowmyanarayanan
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Vaccine 30:A167-72. 2012
    ....
  19. pmc Human caliciviruses in symptomatic and asymptomatic infections in children in Vellore, South India
    Bindhu Monica
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Med Virol 79:544-51. 2007
    ..This is the first report of genotyping of circulating caliciviruses in both hospital and community in India and has increased the evidence for the role of these viruses in pediatric gastroenteritis in India...
  20. pmc Whole genome characterization of reassortant G10P[11] strain (N155) from a neonate with symptomatic rotavirus infection: identification of genes of human and animal rotavirus origin
    Sasirekha Ramani
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Clin Virol 45:237-44. 2009
    ....
  21. pmc Comparative study of the epidemiology of rotavirus in children from a community-based birth cohort and a hospital in South India
    Indrani Banerjee
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, India
    J Clin Microbiol 44:2468-74. 2006
    ..G10P[11] strains resembling a vaccine candidate strain caused disease in the community, indicating the need for careful epidemiological studies as well as safety studies for the vaccine candidates...
  22. pmc Protective effect of natural rotavirus infection in an Indian birth cohort
    Beryl P Gladstone
    Wellcome Trust Research Laboratory, Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    N Engl J Med 365:337-46. 2011
    ..We studied the protective effect of rotavirus infection on subsequent infection and disease in a birth cohort in India (where the efficacy of oral vaccines in general has been lower than expected)...
  23. pmc Modification of rotavirus multiplex RT-PCR for the detection of G12 strains based on characterization of emerging G12 rotavirus strains from South India
    Indrani Banerjee
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Med Virol 79:1413-21. 2007
    ..Methods for characterization of rotaviruses in epidemiological studies need to be updated frequently, particularly in developing countries...
  24. doi request reprint Evidence of intrafamilial transmission of rotavirus in a birth cohort in South India
    Indrani Banerjee
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Med Virol 80:1858-63. 2008
    ..This study is the first to use phylogenetic analysis to study the intrafamilial spread of rotavirus infection...
  25. pmc Exposure to human and bovine noroviruses in a birth cohort in southern India from 2002 to 2006
    Vipin Kumar Menon
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Clin Microbiol 51:2391-5. 2013
    ..Antibodies to genogroup II viruses were acquired early and were more prevalent than antibodies to genogroup I. Low levels of IgG antibodies against bovine noroviruses indicate possible zoonotic transmission...
  26. ncbi request reprint Study of water supply & sanitation practices in India using geographic information systems: some design & other considerations in a village setting
    Srila Gopal
    Department of Community Health, Christian Medical College, Vellore, India
    Indian J Med Res 129:233-41. 2009
    ..We examined the water and sanitation facilities of a village in southern India using geographic information system (GIS) tools...
  27. doi request reprint Rotavirus infection in the neonatal nurseries of a tertiary care hospital in India
    Sasirekha Ramani
    Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Pediatr Infect Dis J 27:719-23. 2008
    ..In this study, we present the results of a 4-year prospective surveillance in the neonatal nurseries of a tertiary care hospital in south India...
  28. doi request reprint Comparison of viral load and duration of virus shedding in symptomatic and asymptomatic neonatal rotavirus infections
    Sasirekha Ramani
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India
    J Med Virol 82:1803-7. 2010
    ..The lack of correlation between viral load and gastrointestinal disease demonstrates yet another difference between neonatal rotavirus infection and infection in older children where higher viral load correlates with severe disease...
  29. pmc Norovirus genogroup II gastroenteritis in hospitalized children in South India
    Vipin Kumar Menon
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India Departments of Child Health Units I, II and III, Christian Medical College, Vellore, India
    Am J Trop Med Hyg 89:1019-22. 2013
    ..002). The study documents NoV GII infections as an important cause of gastroenteritis and the genetic diversity of circulating strains...
  30. doi request reprint Nitric oxide production in acute gastroenteritis in Indian children
    Thuppal Varadachari Sowmyanarayanan
    Department of Gastrointestinal Sciences, Christian Medical College, Tamil Nadu, India
    Trans R Soc Trop Med Hyg 103:849-51. 2009
    ..3-46.7] than without diarrhoea (7.8; IQR 4.1-13.2), P<0.001. The ratio was not significantly different between diarrhoeal cases with and without pathogens (P=0.148). Six of twelve children tested had intestinal dysfunction...
  31. pmc Burden of childhood diseases and malnutrition in a semi-urban slum in southern India
    Rajiv Sarkar
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu 632004, India
    BMC Public Health 13:87. 2013
    ..However, the burden of childhood diseases and malnutrition in such populations is difficult to quantify. The morbidity experience of children living in semi-urban slums of a southern Indian city is described...
  32. pmc Molecular and spatial epidemiology of cryptosporidiosis in children in a semiurban community in South India
    Sitara Swarna Rao Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632 004, India
    J Clin Microbiol 45:915-20. 2007
    ..hominis in a setting where cryptosporidiosis is endemic. Molecular characterization and spatial analysis have the potential to further the understanding of disease and transmission in the community...
  33. pmc Serum IgG responses and seroconversion patterns to Cryptosporidium gp15 among children in a birth cohort in south India
    Rajiv Sarkar
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Clin Vaccine Immunol 19:849-54. 2012
    ..The high degree of seroconversion among control children is suggestive of high rates of asymptomatic transmission in this region...
  34. ncbi request reprint Giardia duodenalis assemblages associated with diarrhea in children in South India identified by PCR-RFLP
    Sitara S R Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Am J Trop Med Hyg 80:16-9. 2009
    ..Assemblage B was predominant both in giardial diarrhea (80%) and asymptomatic giardiasis (94%). Children with Assemblage A subgroup-II alone or dual infections with both assemblage A and B had diarrhea more frequently (P = 0.07)...
  35. doi request reprint Investigation of the environment and of mothers in transmission of rotavirus infections in the neonatal nursery
    Sasirekha Ramani
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Med Virol 80:1099-105. 2008
    ..Interestingly, sequences of amplicons from maternal stool samples did not cluster with G10P[11] or other VP6 subgroup I strains but showed clustering with human strains of VP6 subgroup II...
  36. doi request reprint Pathotypes of diarrheagenic Escherichia coli in children attending a tertiary care hospital in South India
    Priya Rajendran
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Diagn Microbiol Infect Dis 68:117-22. 2010
    ..1%) controls, while mixed infection could be identified in 8/394 (2%) cases and 2/198 (1%) controls...
  37. doi request reprint Rotavirus antigenemia in Indian children with rotavirus gastroenteritis and asymptomatic infections
    Sasirekha Ramani
    Departments of Gastrointestinal Sciences1 and Biostatistics2, Christian Medical College, Vellore, India
    Clin Infect Dis 51:1284-9. 2010
    ..Although there are numerous studies on rotavirus diarrhea, there are few reports on antigenemia and extraintestinal presentations in these populations...
  38. pmc Symptomatic and asymptomatic Cryptosporidium infections in children in a semi-urban slum community in southern India
    Sitara S R Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Am J Trop Med Hyg 83:1110-5. 2010
    ....
  39. pmc Geographic information systems and genotyping in identification of rotavirus G12 infections in residents of an urban slum with subsequent detection in hospitalized children: emergence of G12 genotype in South India
    Sasirekha Ramani
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Clin Microbiol 45:432-7. 2007
    ..Monitoring of cocirculating rotavirus strains and detection of emerging strains is important in the context of the availability of rotavirus vaccines...
  40. pmc Comparison of age-stratified seroprevalence of antibodies against norovirus GII in India and the United Kingdom
    Vipin Kumar Menon
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    PLoS ONE 8:e56239. 2013
    ..These results indicate different patterns of exposure to noroviruses in the two countries...
  41. pmc Investigation of a hepatitis A outbreak in children in an urban slum in Vellore, Tamil Nadu, using geographic information systems
    Thuppal V Sowmyanarayanan
    Departments of Gastrointestinal Sciences, Christian Medical College Vellore, Tamil Nadu, India
    Indian J Med Res 128:32-7. 2008
    ....
  42. pmc Clinical features & risk factors associated with cryptosporidiosis in HIV infected adults in India
    S S Rao Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College Vellore, India
    Indian J Med Res 126:553-7. 2007
    ..We therefore undertook this study to identify risk factors for transmission of cryptosporidiosis in HIV infected adults...
  43. pmc Rotavirus shedding in symptomatic and asymptomatic children using reverse transcription-quantitative PCR
    Indrani Mukhopadhya
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India
    J Med Virol 85:1661-8. 2013
    ..Shedding was intermittent in a subset of children in both groups. RT-qPCR is a useful method to characterize shedding patterns...
  44. pmc Burden of illness in the first 3 years of life in an Indian slum
    Beryl P Gladstone
    Department of Community Health, Christian Medical College, Vellore 632002, India
    J Trop Pediatr 56:221-6. 2010
    ..Of the 77 drop-outs 44 were contacted for mortality data. The morbidity in the area is high, comparable to other studies. The mortality is low, and is attributed to the facilitated access to care...
  45. doi request reprint Investigation of an epidemic of Hepatitis E in Nellore in south India
    Rosario Vivek
    Department of Gastrointestinal Sciences, Christian Medical College, Ida Scudder Road, Vellore, India
    Trop Med Int Health 15:1333-9. 2010
    ..To determine the incidence of acute hepatitis because of hepatitis E virus (HEV) and the source of the epidemic in Nellore in south India in 2008...
  46. doi request reprint Seroprevalence of IgG antibodies to hepatitis E in urban and rural southern India
    Rosario Vivek
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu 632004, India
    Trans R Soc Trop Med Hyg 104:307-8. 2010
    ..001 for all age groups except children <5 years). These results indicate that urban populations with higher density and common water supplies may be at greater risk of hepatitis E...
  47. pmc Serum IgG response to Cryptosporidium immunodominant antigen gp15 and polymorphic antigen gp40 in children with cryptosporidiosis in South India
    Sitara Swarna Rao Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, TN 632004, India
    Clin Vaccine Immunol 18:633-9. 2011
    ..However, further studies are needed to determine whether immune responses to these antigens are protective against subsequent infections...
  48. ncbi request reprint Epidemiological investigation of an outbreak of acute diarrhoeal disease using geographic information systems
    Rajiv Sarkar
    Department of Community Health, Christian Medical College, Vellore 632 002, Tamil Nadu, India
    Trans R Soc Trop Med Hyg 101:587-93. 2007
    ....
  49. ncbi request reprint Water contamination in urban south India: household storage practices and their implications for water safety and enteric infections
    Thomas Brick
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Int J Hyg Environ Health 207:473-80. 2004
    ..The implementation of locally appropriate point-of-use disinfection and safe household storage practices in developing countries is an urgent need to ensure a safe, reliable year-round supply in areas where clean water is not available...
  50. doi request reprint Characterization of hepatitis E virus from sporadic hepatitis cases and sewage samples from Vellore, south India
    Rosario Vivek
    Wellcome Trust Research Laboratory, Division of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, India
    Trans R Soc Trop Med Hyg 107:363-7. 2013
    ..However, the exact transmission route for sporadic hepatitis E remains unclear. This study investigated HEV in sporadic hepatitis cases and sewage samples, as sewage is the major source of contamination of water in developing countries...
  51. pmc Direct costs of hospitalization for rotavirus gastroenteritis in different health facilities in India
    T V Sowmyanarayanan
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Indian J Med Res 136:68-73. 2012
    ..This pilot study was conducted to determine the economic burden of diarrhoeal episodes on families from different geographical regions accessing medical facilities in India...
  52. pmc Investigation of potential zoonotic transmission of cryptosporidiosis in southern India
    Priya Rajendran
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Am J Trop Med Hyg 85:657-9. 2011
    ..Although no zoonotic strains were identified in 13 infected children, 1 of 12 infected animals had C. hominis, indicating the potential for cross-species transmission. This study also reports C. xiaoi for the first time in India...
  53. doi request reprint Multicenter, hospital-based surveillance of rotavirus disease and strains among indian children aged <5 years
    Gagandeep Kang
    Christian Medical College, Vellore, New Delhi, India
    J Infect Dis 200:S147-53. 2009
    ..Current, nationally representative data on rotavirus disease burden and rotavirus strains in India are needed to understand the potential health benefits of rotavirus vaccination...
  54. pmc Estimates of the economic burden of rotavirus-associated and all-cause diarrhoea in Vellore, India
    Andrea S Mendelsohn
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Trop Med Int Health 13:934-42. 2008
    ..To determine the cost of rotavirus and all-cause diarrhoea in Vellore, India...
  55. ncbi request reprint Cryptosporidium species in HIV-infected individuals in India: an overview
    Sitara Swarna Rao Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632002, Tamil Nadu, India
    Natl Med J India 21:178-84. 2008
    ..Therefore, data from different parts of India form a necessary baseline against which the effect of antiretroviral therapy can be evaluated...
  56. pmc Burden of disease & molecular epidemiology of group A rotavirus infections in India
    Sasirekha Ramani
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Indian J Med Res 125:619-32. 2007
    ..The emergence of several new strains highlights the need for intensive strain surveillance before and after the introduction of a new vaccine...
  57. pmc Cryptosporidiosis among children in an endemic semiurban community in southern India: does a protected drinking water source decrease infection?
    Rajiv Sarkar
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India
    Clin Infect Dis 57:398-406. 2013
    ..A quasi-experimental study was conducted to determine whether or not a protected water supply (bottled drinking water) could prevent or delay cryptosporidial infections among children residing in an endemic community...
  58. ncbi request reprint Intestinal mucosal alterations in rats with carbon tetrachloride-induced cirrhosis: changes in glycosylation and luminal bacteria
    Sathish Kumar Natarajan
    The Wellcome Trust Research Laboratory, Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Hepatology 43:837-46. 2006
    ..This might facilitate translocation across the mucosa, resulting in complications such as spontaneous bacterial peritonitis...
  59. pmc Surgical manipulation of the intestine results in quantitative and qualitative alterations in luminal Escherichia coli
    Simmy Thomas
    Wellcome Trust Research Laboratory, Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Ann Surg 240:248-54. 2004
    ..To look at the qualitative and quantitative changes in the luminal bacterial flora in response to surgical manipulation of the small intestine...
  60. pmc Retrospective surveillance for intussusception in children aged less than five years in a South Indian tertiary-care hospital
    Kaushik Bhowmick
    Christian Medical College, Vellore 632 004, India
    J Health Popul Nutr 27:660-5. 2009
    ..Prospective surveillance systems, using standardized case definitions will further increase the understanding of the aetiology and epidemiology of intussusception, especially as new rotavirus vaccines are made available...
  61. doi request reprint Diversity of circulating rotavirus strains in children hospitalized with diarrhea in India, 2005-2009
    Gagandeep Kang
    Christian Medical College, Vellore 632002, India
    Vaccine 31:2879-83. 2013
    ..Our analysis offers policy-makers an update on rotavirus disease burden with emphasis on regional shifts in rotavirus strain epidemiology in India...
  62. ncbi request reprint Water handling, sanitation and defecation practices in rural southern India: a knowledge, attitudes and practices study
    Kalyan Banda
    Christian Medical College, Vellore, India
    Trans R Soc Trop Med Hyg 101:1124-30. 2007
    ..02) and low socio-economic status (P<0.001) were significantly different between the Main village and the Harijan colony. Traditional practices may pose a significant challenge to programmes aimed at toilet usage and better sanitation...
  63. pmc Faecal bifidobacteria in Indian neonates & the effect of asymptomatic rotavirus infection during the first month of life
    Ramadass Balamurugan
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Indian J Med Res 132:721-7. 2010
    ....
  64. ncbi request reprint Real-time PCR detection and speciation of Cryptosporidium infection using Scorpion probes
    Suzanne E Stroup
    Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA 22908, USA, and Department of Gastrointestinal Sciences and Haematology, Christian Medical College and Hospital, Vellore, India
    J Med Microbiol 55:1217-22. 2006
    ..These Scorpion probe qPCR assays are simpler to perform than existing nested PCR and RFLP methods for diagnosis and epidemiological investigation of cryptosporidiosis...
  65. ncbi request reprint Faecal lactoferrin as a predictor of positive faecal culture in south Indian children with acute diarrhoea
    S Venkataraman
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore, India
    Ann Trop Paediatr 23:9-13. 2003
    ....
  66. pmc Analysis of human immune responses in quasi-experimental settings: tutorial in biostatistics
    Rajiv Sarkar
    Christian Medical College, Vellore, India
    BMC Med Res Methodol 12:1. 2012
    ..However, rigorous discussion of methodological issues related to designs and statistical analysis that are appropriate for longitudinal studies is lacking...
  67. doi request reprint Giardiasis: a review on assemblage distribution and epidemiology in India
    Shakti Laishram
    Department of Microbiology, Christian Medical College, Vellore 632 004, India
    Indian J Gastroenterol 31:3-12. 2012
    ..In this review, the global distribution of giardial assemblage, zoonotic transmission and the association of assemblage with disease have been discussed, followed by epidemiology of giardiasis in India...
  68. pmc Transmission dynamics of methicillin-resistant Staphylococcus aureus in a medical intensive care unit in India
    Solomon Christopher
    Department of Biostatistics, Christian Medical College, Vellore, India
    PLoS ONE 6:e20604. 2011
    ..We analyse the transmission dynamics of MRSA in a hospital in south India using one such approach and provide conservative estimates of the organism's economic burden...
  69. ncbi request reprint Locally made ready to use therapeutic food for treatment of malnutrition a randomized controlled trial
    Azara Sneha Singh
    Departments of Gastrointestinal Sciences and Community Health, Christian Medical College, Vellore TN 632004, India
    Indian Pediatr 47:679-86. 2010
    ..To evaluate the effectiveness of a locally made ready-to-use therapeutic food (RUTF) in decreasing mild to moderate malnutrition...
  70. doi request reprint Viruses causing childhood diarrhoea in the developing world
    Sasirekha Ramani
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India
    Curr Opin Infect Dis 22:477-82. 2009
    ..This review focuses on enteric viruses and their role in childhood diarrhoea in the developing world...
  71. pmc Hepatitis E virus infections in swine and swine handlers in Vellore, Southern India
    Rosario Vivek
    Wellcome Trust Research Laboratory, Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India
    Am J Trop Med Hyg 84:647-9. 2011
    ..The HEV genotype circulating in swine in India is different from that of humans, but the higher antibody levels in swine handlers support the possibility that zoonotic infections may occur...
  72. ncbi request reprint A study on some phenotypic virulence markers of enteropathogenic Escherichia coli
    M Prasannan
    Departments of Microbiology and Virology, Christian Medical College and Hospital, Vellore, India
    Indian J Med Res 114:95-8. 2001
    ..INTERPRETATION & CONCLUSION: 'O' serogrouping appears to be still the simplest and an useful test for presumptive identification of EPEC. The FAS test for confirmation of EPEC was found to be very consistent in indicating EPEC...
  73. pmc Comparison of group counseling with individual counseling in the comprehension of informed consent: a randomized controlled trial
    Rajiv Sarkar
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632 004, Tamil Nadu, India
    BMC Med Ethics 11:8. 2010
    ....
  74. doi request reprint Early activation of mucosal dendritic cells and macrophages in acute Campylobacter colitis and cholera: An in vivo study
    Anna B Pulimood
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India
    J Gastroenterol Hepatol 23:752-8. 2008
    ..Little is known about their in vivo role in acute intestinal bacterial infections in humans. We undertook to evaluate these cells in rectal mucosal biopsies of patients with acute colitis...
  75. doi request reprint Gap in the prevalence of neutralising antibodies to polioviruses in antenatal women in southern India
    Jacob John
    Department of Community Health, Christian Medical College, Vellore 632002, Tamil Nadu, India
    Trans R Soc Trop Med Hyg 105:179-80. 2011
    ..These findings represent a possible immunity gap and this needs to be confirmed with further studies, which could include a challenge with vaccine virus...
  76. pmc Polymerase chain reaction in the detection of an 'outbreak' of asymptomatic viral infections in a community birth cohort in south India
    B P Gladstone
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Epidemiol Infect 136:399-405. 2008
    ..Asymptomatically infected children may also act as a source of infection for other susceptible hosts...
  77. ncbi request reprint Salicylate inhibits fimbriae mediated HEp-2 cell adherence of and haemagglutination by enteroaggregative Escherichia coli
    G Kang
    Wellcome Trust Research Laboratory, I C M R Centre for Advanced Research on Enteric Diseases, Department of Gastrointestinal Sciences, Vellore, India
    FEMS Microbiol Lett 166:257-65. 1998
    ..Salicylates appear to inhibit adherence mediated by fimbrial adhesins...
  78. ncbi request reprint The pathogenesis and laboratory diagnosis of infections caused by diarrhoea producing Escherichia coli
    G Kang
    Christian Medical College, Vellore, Tamil Nadu, India
    Natl Med J India 9:168-73. 1996
    ..This article reviews modern microbiological techniques which have enhanced our knowledge of the pathogenesis of infections caused by diarrhoeagenic E. coli and the various new diagnostic techniques available...
  79. doi request reprint Closing the diarrhoea diagnostic gap in Indian children by the application of molecular techniques
    S S R Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    J Med Microbiol 57:1364-8. 2008
    ....
  80. doi request reprint Anti-VP6 IgG antibodies against group A and group C rotaviruses in South India
    I Mukhopadhya
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Epidemiol Infect 138:442-7. 2010
    ..79%). An age-related rise in seroprevalence in group C, but not group A, suggests different patterns of exposure. Seroprevalence was similar in rural and urban subjects, unlike the higher prevalence in rural subjects in studies elsewhere...
  81. ncbi request reprint Microbes in the gut: a digestable account of host-symbiont interactions
    Rekha Pai
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Indian J Med Res 128:587-94. 2008
    ..Although gut flora are implicated in certain pathological disorders, their remarkable contributions to health and homeostasis of the host need to be recognized and understood...
  82. ncbi request reprint Hepatitis E superinfection produces severe decompensation in patients with chronic liver disease
    Jeyamani Ramachandran
    Departments of Gastrointestinal Sciences and Clinical Virology, Christian Medical College, Vellore, Tamilnadu, India
    J Gastroenterol Hepatol 19:134-8. 2004
    ....
  83. ncbi request reprint A prospective study of nosocomial enteric pathogen acquisition in hospitalized children in South India
    C N Kamalaratnam
    Department of Child Health, Christian Medical College and Hospital, Vellore, India
    J Trop Pediatr 47:46-9. 2001
    ..One in five children admitted into hospital without an enteric infection is at risk of developing a nosocomial gastrointestinal infection, with rotavirus being the most common aetiological agent...
  84. pmc Epidemiological and laboratory investigations of outbreaks of diarrhoea in rural South India: implications for control of disease
    G Kang
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore, India
    Epidemiol Infect 127:107-12. 2001
    ..Point-of-use techniques for water disinfection may be most effective for preventing such outbreaks, but further research into the development of appropriate technology is required...
  85. pmc Infant mortality in an urban slum
    A Vaid
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India
    Indian J Pediatr 74:449-53. 2007
    ..In order to formulate appropriate local policies for intervention, it is important to know the patterns of morbidity and mortality in children in the local setting...
  86. pmc Infant morbidity in an Indian slum birth cohort
    B P Gladstone
    Department of Community Health, Christian Medical College, Vellore, India
    Arch Dis Child 93:479-84. 2008
    ..To establish incidence rates, clinic referrals, hospitalisations, mortality rates and baseline determinants of morbidity among infants in an Indian slum...
  87. pmc Solar disinfection of water for diarrhoeal prevention in southern India
    A Rose
    Department of Community Health, Christian Medical College, Vellore, TN 632004, India
    Arch Dis Child 91:139-41. 2006
    ..To evaluate the efficacy and acceptability of solar irradiation in the prevention of diarrhoeal morbidity in children under 5 years of age, in an urban slum in Vellore, Tamil Nadu...
  88. pmc Rotavirus infection enhances lipopolysaccharide-induced intussusception in a mouse model
    Kelly L Warfield
    Department of Molecular Virology and Microbiology, One Baylor Plaza, Baylor College of Medicine, Houston, TX 77030, USA
    J Virol 80:12377-86. 2006
    ..Together, these data suggest that rotavirus infection sensitized mice to the inflammatory effects of subsequent LPS treatment to enhance intussusception rates...
  89. pmc Evidence for genetic linkage between the gene segments encoding NSP4 and VP6 proteins in common and reassortant human rotavirus strains
    Miren Iturriza-Gomara
    Enteric Virus Unit, Enteric, Respiratory and Neurological Virus Laboratory, Health Protection Agency, London, United Kingdom
    J Clin Microbiol 41:3566-73. 2003
    ..The NSP4-VP6 association may be structurally determined during rotavirus replication (morphogenesis)...
  90. pmc Evaluation of serum antibody responses against the rotavirus nonstructural protein NSP4 in children after rhesus rotavirus tetravalent vaccination or natural infection
    Esmeralda Vizzi
    Laboratorio de BiologĂ­a de Virus, Centro de Microbiologia y Biologia Celular, Instituto Venezolano de Investigaciones Cientificas IVIC, Carretera Panamericana Km 11, Caracas, 1020 A, Edo Miranda, Venezuela
    Clin Diagn Lab Immunol 12:1157-63. 2005
    ..In addition, previous exposures to rotavirus did not affect the NSP4 seroconversion rate...
  91. ncbi request reprint Rotavirus genotyping: keeping up with an evolving population of human rotaviruses
    Miren Iturriza-Gomara
    Enteric Virus Unit, Enteric Respiratory and Neurological Virus Laboratory, Specialist and Reference Microbiology Division, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK
    J Clin Virol 31:259-65. 2004
    ..Methods and oligonucleotide primers are described to overcome failures to type G9, G10 and P[11] rotavirus strains, and cross-reactivity identified between G10 and G3 rotaviruses...
  92. pmc Characterization of G10P[11] rotaviruses causing acute gastroenteritis in neonates and infants in Vellore, India
    Miren Iturriza Gomara
    Enteric Virus Unit, Enteric Respiratory and Neurological Virus Laboratory, Health Protection Agency, 61 Colindale Ave, London NW9 5HT, United Kingdom
    J Clin Microbiol 42:2541-7. 2004
    ..No significant differences were seen in the sequences obtained from strains infecting symptomatic neonates or children and asymptomatic neonates...
  93. doi request reprint Rotavirus epidemiology: the Asian Rotavirus Surveillance Network
    E A S Nelson
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong SAR, China
    Vaccine 26:3192-6. 2008
    ....
  94. ncbi request reprint Rotavirus genotypes and severity of diarrheal disease
    Gagandeep Kang
    Clin Infect Dis 43:315-6. 2006

Research Grants3

  1. Transmission dynamics of cryptosporidial infections in India
    Gagandeep Kang; Fiscal Year: 2010
    ..These data will provide the basis for the logical development of interventions that are appropriate to the developing country communities in which cryptosporidiosis is common. ..