C E Eapen

Summary

Affiliation: Christian Medical College
Country: India

Publications

  1. ncbi request reprint Acute fatty liver of pregnancy: a report of two cases
    G Loganathan
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore 632004, Tamil Nadu, India
    Natl Med J India 15:336-8. 2002
  2. ncbi request reprint Changing profile of Budd Chiari syndrome in India
    C E Eapen
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632 004, Tamil Nadu, India
    Indian J Gastroenterol 26:77-81. 2007
  3. ncbi request reprint Liver failure during pregnancy
    C E Eapen
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India
    Gut 57:83. 2008
  4. pmc A study of aetiology of portal hypertension in adults (including the elderly) at a tertiary centre in southern India
    Ashish Goel
    Department of Hepatology, Christian Medical College, Vellore, India
    Indian J Med Res 137:922-7. 2013
  5. doi request reprint Non-cirrhotic intrahepatic portal hypertension: associated gut diseases and prognostic factors
    C E Eapen
    Liver Unit, Queen Elizabeth Hospital, and Department of Pathology, University of Birmingham, Edgbaston, Birmingham, B15 2TH, UK
    Dig Dis Sci 56:227-35. 2011
  6. pmc Genotype phenotype correlation in Wilson's disease within families--a report on four south Indian families
    S Santhosh
    Department of Gastrointestinal Sciences Christian Medical College, Vellore, Tamil Nadu, India
    World J Gastroenterol 14:4672-6. 2008
  7. doi request reprint Use of serum vitamin B12 level as a marker to differentiate idiopathic noncirrhotic intrahepatic portal hypertension from cryptogenic cirrhosis
    Ashish Goel
    Hepatology Department, Christian Medical College, Vellore, Tamil Nadu, 632004, India
    Dig Dis Sci 58:179-87. 2013
  8. doi request reprint Association of HLA and TNF polymorphisms with the outcome of HBV infection in the South Indian population
    G J Fletcher
    Department of Clinical Virology, Christian Medical College, Vellore, Tamil Nadu, India
    Genes Immun 12:552-8. 2011
  9. doi request reprint Idiopathic non-cirrhotic intrahepatic portal hypertension: common cause of cryptogenic intrahepatic portal hypertension in a Southern Indian tertiary hospital
    Kadiyala Madhu
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Indian J Gastroenterol 28:83-7. 2009
  10. doi request reprint Infection with hepatitis C virus genotype 3--experience of a tertiary health care centre in south India
    J David
    Department of Clinical Virology, Christian Medical College, Vellore 632 004, India
    Indian J Med Microbiol 28:155-7. 2010

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Acute fatty liver of pregnancy: a report of two cases
    G Loganathan
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore 632004, Tamil Nadu, India
    Natl Med J India 15:336-8. 2002
    ..Liver biopsy done in both patients was consistent with the diagnosis of acute fatty liver of pregnancy. To the best of our knowledge, this is the first report from India on acute fatty liver of pregnancy...
  2. ncbi request reprint Changing profile of Budd Chiari syndrome in India
    C E Eapen
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632 004, Tamil Nadu, India
    Indian J Gastroenterol 26:77-81. 2007
    ..Improvement in hygiene and sanitation may partly explain the recent change in disease profile of Budd Chiari syndrome in India...
  3. ncbi request reprint Liver failure during pregnancy
    C E Eapen
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India
    Gut 57:83. 2008
  4. pmc A study of aetiology of portal hypertension in adults (including the elderly) at a tertiary centre in southern India
    Ashish Goel
    Department of Hepatology, Christian Medical College, Vellore, India
    Indian J Med Res 137:922-7. 2013
    ....
  5. doi request reprint Non-cirrhotic intrahepatic portal hypertension: associated gut diseases and prognostic factors
    C E Eapen
    Liver Unit, Queen Elizabeth Hospital, and Department of Pathology, University of Birmingham, Edgbaston, Birmingham, B15 2TH, UK
    Dig Dis Sci 56:227-35. 2011
    ..We have studied a cohort followed-up at a tertiary referral center and postulate that gut-derived prothrombotic factors may contribute to the pathogenesis and prognosis of NCIPH...
  6. pmc Genotype phenotype correlation in Wilson's disease within families--a report on four south Indian families
    S Santhosh
    Department of Gastrointestinal Sciences Christian Medical College, Vellore, Tamil Nadu, India
    World J Gastroenterol 14:4672-6. 2008
    ..To study the genotype phenotype correlation in Wilson's disease (WD) patients within families...
  7. doi request reprint Use of serum vitamin B12 level as a marker to differentiate idiopathic noncirrhotic intrahepatic portal hypertension from cryptogenic cirrhosis
    Ashish Goel
    Hepatology Department, Christian Medical College, Vellore, Tamil Nadu, 632004, India
    Dig Dis Sci 58:179-87. 2013
    ..Because NCIPH is characterised by long periods of preserved liver function, we examined whether serum B12 level could be used as a marker to differentiate NCIPH from cryptogenic cirrhosis...
  8. doi request reprint Association of HLA and TNF polymorphisms with the outcome of HBV infection in the South Indian population
    G J Fletcher
    Department of Clinical Virology, Christian Medical College, Vellore, Tamil Nadu, India
    Genes Immun 12:552-8. 2011
    ..0004). Our study suggests that inheritance of HLA and TNF polymorphisms might explain the outcome of HBV infection in the South Indian population...
  9. doi request reprint Idiopathic non-cirrhotic intrahepatic portal hypertension: common cause of cryptogenic intrahepatic portal hypertension in a Southern Indian tertiary hospital
    Kadiyala Madhu
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India
    Indian J Gastroenterol 28:83-7. 2009
    ..The aim of this study was to evaluate causes of liver disease in patients with unexplained intrahepatic portal hypertension...
  10. doi request reprint Infection with hepatitis C virus genotype 3--experience of a tertiary health care centre in south India
    J David
    Department of Clinical Virology, Christian Medical College, Vellore 632 004, India
    Indian J Med Microbiol 28:155-7. 2010
    ..Absence of early viral response (EVR) showed high (80%) predictive value on SVR. Absence of EVR and normalisation of the ALT levels can predict the outcome of HCV antiviral therapy...
  11. doi request reprint Hepatocellular carcinoma continues to be diagnosed in the advanced stage: profile of hepatocellular carcinoma in a tertiary care hospital in South India
    Sandip Pal
    Departments of GI Sciences, Christian Medical College, Vellore, India
    Trop Doct 43:25-6. 2013
    ..Physician awareness of this complication of cirrhosis and regular ultrasound screening of cirrhotic patients will help in detection of early stage cancers and, thus, enhance the survival rates...
  12. doi request reprint Antiviral resistance mutations and genotype-associated amino acid substitutions in treatment-naïve hepatitis B virus-infected individuals from the Indian subcontinent
    A M Ismail
    Department of Clinical Virology, Christian Medical College, Vellore, India
    Intervirology 55:36-44. 2012
    ..Antiviral resistance is a major challenge to the treatment currently available for hepatitis B virus (HBV). In this study, mutations that may affect the antiviral efficacy in treatment-naïve HBV-infected individuals were analyzed...
  13. doi request reprint Association of mannose-binding lectin polymorphisms and HBV outcome in a South Indian population
    G J Fletcher
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu, India
    Int J Immunogenet 37:177-84. 2010
    ..Our results provide preliminary evidence that inheritance of codon 52 genotypes and XY/O haplotype associated with low MBL level substantially determine the outcome of HBV infection in a sympatrically isolated South Indian population...
  14. doi request reprint Genetics of Wilson's disease: a clinical perspective
    S Suresh Kumar
    Department of Hepatology, Christian Medical College, Vellore 632 004, Tamil Nadu, India
    Indian J Gastroenterol 31:285-93. 2012
    ..The non-Wilsonian copper overload syndromes causing cirrhosis in children are another important area for study. The review also identifies further areas for research into the genetics of Wilson's disease in India...
  15. doi request reprint Transjugular liver biopsy: a retrospective analysis of 601 cases
    Thomas Mammen
    Department of Radiology, Christian Medical College Hospital, Vellore, India
    J Vasc Interv Radiol 19:351-8. 2008
    ..The authors discuss the technical modifications adopted to achieve better procedural success and histopathologic yield apart from the safety profile of this procedure during the study period...
  16. doi request reprint Investigation of an epidemic of Hepatitis E in Nellore in south India
    Rosario Vivek
    Department of Gastrointestinal Sciences, Christian Medical College, Ida Scudder Road, Vellore, India
    Trop Med Int Health 15:1333-9. 2010
    ..To determine the incidence of acute hepatitis because of hepatitis E virus (HEV) and the source of the epidemic in Nellore in south India in 2008...
  17. doi request reprint Liver injury in acute fatty liver of pregnancy: possible link to placental mitochondrial dysfunction and oxidative stress
    Sathish Kumar Natarajan
    The Wellcome Trust Research Laboratory, Department of Gastrointestinal Sciences, Vellore, India
    Hepatology 51:191-200. 2010
    ..These levels of arachidonic acid were capable of inducing oxidative stress in hepatocyte mitochondria accompanied by induction of apoptosis. Exposure to arachidonic acid also resulted in increased lipid deposition in hepatocytes...
  18. doi request reprint Preliminary experience with use of recombinant activated factor VII to control postpartum hemorrhage in acute fatty liver of pregnancy and other pregnancy-related liver disorders
    Ashish Goel
    Department of Hepatology, Christian Medical College, Vellore 632 004, India
    Indian J Gastroenterol 32:268-71. 2013
    ..No patient had thrombotic complications. In conclusion, rFVIIa was a useful adjunct to standard management in postpartum hemorrhage secondary to acute liver failure of pregnancy-related liver disorders...
  19. doi request reprint Intrahepatic collateral recanalization in symptomatic Budd-Chiari syndrome: a single-center experience
    Thomas Mammen
    Department of Radiology, Christian Medical College and Hospital, Vellore, India
    J Vasc Interv Radiol 21:1119-24. 2010
    ..Based on these cases, intrahepatic collateral vessel recanalization is a promising treatment option in suitable patients with symptomatic BCS and is deserving of further study...
  20. ncbi request reprint Liver histology and immunohistochemical findings in asymptomatic Indians with incidental detection of hepatitis B virus infection
    Ashis Mukhopadhya
    Department of GI Sciences, Christian Medical College and Hospital, Vellore 632 004, India
    Indian J Gastroenterol 25:128-31. 2006
    ..We evaluated the histological activity index (HAI) and hepatocyte expression of viral antigens with replicative status in asymptomatic chronic HBV infection...
  21. pmc Transjugular intrahepatic portocaval shunt placed through the strut of an inferior vena cava stent in a patient with Budd-Chiari syndrome: a technical modification
    N R S Surendrababu
    Department of Radiology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India
    Br J Radiol 83:e22-4. 2010
    ..This novel technique of "strutplasty" of a previously placed stent as part of TIPS has not been reported in the literature...
  22. doi request reprint Serum HBsAg quantification in treatment-naïve Indian patients with chronic hepatitis B
    Jeyamani Ramachandran
    Department of Hepatology, Christian Medical College, Vellore, 632 004, India
    Indian J Gastroenterol 33:131-5. 2014
    ..This study was done to determine correlation of qHBsAg with hepatitis B e antigen (HBeAg) and hepatitis B virus (HBV) DNA levels and its ability to independently categorize subgroups of CHB...
  23. ncbi request reprint Hepatitis E superinfection produces severe decompensation in patients with chronic liver disease
    Jeyamani Ramachandran
    Departments of Gastrointestinal Sciences and Clinical Virology, Christian Medical College, Vellore, Tamilnadu, India
    J Gastroenterol Hepatol 19:134-8. 2004
    ....
  24. doi request reprint Relationship between clock and star drawing and the degree of hepatic encephalopathy
    Natasha Edwin
    Christian Medical College, Vellore, Tamilnadu, India
    Postgrad Med J 87:605-11. 2011
    ..70 for star and at least 0.79 for the clock score. CONCLUSION Clock and star drawing may serve as reproducible, inexpensive bedside tools for diagnosing and grading the severity of hepatic encephalopathy...
  25. doi request reprint Aetiology of paediatric portal hypertension - experience of a tertiary care centre in South India
    Ebby G Simon
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632004, Tamil Nadu, India
    Trop Doct 39:42-4. 2009
    ..Wilson's disease was the most common cause of cirrhosis...
  26. doi request reprint Transvenous embolization to treat uncontrolled hemobilia and peritoneal bleeding after transjugular liver biopsy
    Chiramel George Koshy
    Department of Radiology, Christian Medical College, Vellore, Tamil Nadu 632004, India
    Cardiovasc Intervent Radiol 33:624-6. 2010
    ..We describe a patient who developed uncontrolled hemobilia after a transjugular liver biopsy that required a transvenous approach for embolization and treatment purposes...
  27. ncbi request reprint Branding to treat jaundice in India
    Selva Inita John
    Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore 632004, India
    Trop Gastroenterol 30:241-2. 2009
    ..Our report suggests that despite being literate, strong cultural beliefs lead people to seek potentially harmful procedures like branding to treat jaundice in parts of India...
  28. pmc Usefulness of ferroxidase activity of ceruloplasmin in the diagnosis of Wilson's disease
    J J Fleming
    Department of Clinical Biochemistry, CMC Vellore, 632 004 Tamil Nadu, India Department of Clinical Biochemistry, Christian Medical College, Vellore, 632004 Tamil Nadu, India
    Indian J Clin Biochem 24:15-22. 2009
    ..908, p < 0.01, slope 4.06, intercept 265.8, with the manual assay as the x-axis. The ferroxidase assay is a suitable replacement for the o-dianisidine assay in detecting patients with Wilson's disease...
  29. ncbi request reprint ATP7B mutations in families in a predominantly Southern Indian cohort of Wilson's disease patients
    S Santhosh
    Department of GI Sciences, Christian Medical College, Vellore, India
    Indian J Gastroenterol 25:277-82. 2006
    ..To analyze ATP7B mutations in Wilson's disease (WD) patients from the Indian subcontinent and to correlate these with WD phenotype...
  30. ncbi request reprint Intussusception in southern Indian children: lack of association with diarrheal disease and oral polio vaccine immunization
    T Raman
    Department of Gastrointestinal Sciences, Christian Medical College Hospital, Vellore 632 004
    Indian J Gastroenterol 22:82-4. 2003
    ..Intussusception is the most common cause of intestinal obstruction in young children and has been reported as a complication of a recently withdrawn tetravalent reassortant rotavirus vaccine...
  31. pmc Favourable medium term outcome following hepatic vein recanalisation and/or transjugular intrahepatic portosystemic shunt for Budd Chiari syndrome
    C E Eapen
    Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2TH, UK
    Gut 55:878-84. 2006
    ..In this series of patients with Budd Chiari syndrome treated with radiological interventions alone, we assess their medium term outcome using two independent objective prognostic indices...
  32. ncbi request reprint Serum and urinary fucose concentrations in hepatitis B-related cirrhosis and acute liver diseases
    N Sathish Kumar
    Clin Chim Acta 342:233-5. 2004
  33. ncbi request reprint Liver function tests in normal pregnancy: a study from southern India
    G Loganathan
    Indian J Gastroenterol 24:268-9. 2005
  34. ncbi request reprint Infrequent occurrence of silent HBV infection among Indian patients with chronic liver disease
    S Radhakrishnan
    Department of Clinical Virology, Christian Medical College and Hospital, Vellore
    Indian J Gastroenterol 20:87-9. 2001
    ..Silent HBV infection is not associated with HCV-related CLD, which is in contrast to reports from other HBV-endemic areas in Asia...