Purnima Bhargava

Summary

Affiliation: Centre for Cellular and Molecular Biology
Country: India

Publications

  1. ncbi request reprint Regulation of activity of the yeast TATA-binding protein through intra-molecular interactions
    Perumal Vanathi
    Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India
    J Biosci 28:413-21. 2003
  2. pmc Yeast H2A.Z, FACT complex and RSC regulate transcription of tRNA gene through differential dynamics of flanking nucleosomes
    Sahasransu Mahapatra
    Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Uppal Road, Hyderabad 500007, India
    Nucleic Acids Res 39:4023-34. 2011
  3. pmc Systematic characterization of the conformation and dynamics of budding yeast chromosome XII
    Benjamin Albert
    Laboratoire de Biologie Moléculaire des Eucaryotes du Centre National de la Recherche Scientifique, Universite de Toulouse, F 31000 Toulouse, France
    J Cell Biol 202:201-10. 2013
  4. doi request reprint Epigenetic regulation of transcription by RNA polymerase III
    Purnima Bhargava
    Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Uppal Road, Hyderabad 500007, India Electronic address
    Biochim Biophys Acta 1829:1015-25. 2013
  5. doi request reprint Epigenetics to proteomics: from yeast to brain
    Purnima Bhargava
    Centre for Cellular and Molecular Biology Council of Scientific and Industrial Research, Tarnaka, Hyderabad, India
    Proteomics 10:749-70. 2010
  6. pmc Multiple sequence-directed possibilities provide a pool of nucleosome position choices in different states of activity of a gene
    Vinesh Vinayachandran
    Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Uppal Road, Hyderabad 500007, India
    Epigenetics Chromatin 2:4. 2009
  7. pmc Chromatin structure and expression of a gene transcribed by RNA polymerase III are independent of H2A.Z deposition
    Aneeshkumar Gopalakrishnan Arimbasseri
    Centre for Cellular and Molecular Biology, Uppal Road, Tarnaka, Hyderabad 500007, India
    Mol Cell Biol 28:2598-607. 2008
  8. ncbi request reprint Positioned nucleosomes due to sequential remodeling of the yeast U6 small nuclear RNA chromatin are essential for its transcriptional activation
    Sushma Shivaswamy
    Centre for Cellular and Molecular Biology, Uppal Road, Tarnaka, Hyderabad 500007, India
    J Biol Chem 281:10461-72. 2006
  9. ncbi request reprint The transcriptional activator GAL4-VP16 regulates the intra-molecular interactions of the TATA-binding protein
    Anurag Kumar Mishra
    Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India
    J Biosci 28:423-36. 2003
  10. ncbi request reprint Nucleosome positioning in relation to nucleosome spacing and DNA sequence-specific binding of a protein
    Rama Haritha Pusarla
    Centre for Cellular and Molecular Biology, Hyderabad, India
    FEBS J 274:2396-410. 2007

Collaborators

  • Julien Mozziconacci
  • Yatendra Kumar
  • George A Kassavetis
  • Rama Haritha Pusarla
  • Devendra Kumar Maurya
  • Sushma Shivaswamy
  • Vinesh Vinayachandran
  • Benjamin Albert
  • Sahasransu Mahapatra
  • Curam Sreenivasacharlu Sundaram
  • Anurag Kumar Mishra
  • Perumal Vanathi
  • Aneeshkumar Gopalakrishnan Arimbasseri
  • Alain Kamgoue
  • Olivier Gadal
  • Ashutosh Shukla
  • Christophe Normand
  • Christophe Zimmer
  • Aurélien Bancaud
  • Hicham Saad
  • David Villa
  • Isabelle Léger-Silvestre
  • Hua Wong
  • Julien Mathon
  • Anubhav Bhardwaj
  • Pooran S Dewari

Detail Information

Publications15

  1. ncbi request reprint Regulation of activity of the yeast TATA-binding protein through intra-molecular interactions
    Perumal Vanathi
    Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India
    J Biosci 28:413-21. 2003
    ..Therefore for full-length TBP, intra-molecular interactions can regulate its activity via a similar mechanism...
  2. pmc Yeast H2A.Z, FACT complex and RSC regulate transcription of tRNA gene through differential dynamics of flanking nucleosomes
    Sahasransu Mahapatra
    Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Uppal Road, Hyderabad 500007, India
    Nucleic Acids Res 39:4023-34. 2011
    ....
  3. pmc Systematic characterization of the conformation and dynamics of budding yeast chromosome XII
    Benjamin Albert
    Laboratoire de Biologie Moléculaire des Eucaryotes du Centre National de la Recherche Scientifique, Universite de Toulouse, F 31000 Toulouse, France
    J Cell Biol 202:201-10. 2013
    ..Our comprehensive investigation of chromosome XII is thus in agreement with recent studies and models in which long-range architecture is largely determined by the physical principles of tethered polymers and volume exclusion...
  4. doi request reprint Epigenetic regulation of transcription by RNA polymerase III
    Purnima Bhargava
    Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Uppal Road, Hyderabad 500007, India Electronic address
    Biochim Biophys Acta 1829:1015-25. 2013
    ..This review presents a summary of the research in past many years, which have gathered enough evidence to conclude that pol III-transcribed genes are important components of an epigenome. ..
  5. doi request reprint Epigenetics to proteomics: from yeast to brain
    Purnima Bhargava
    Centre for Cellular and Molecular Biology Council of Scientific and Industrial Research, Tarnaka, Hyderabad, India
    Proteomics 10:749-70. 2010
    ..As the current understanding of epigenetics can be applied to understand the mysteries of normal brain function as well as various diseases, modern proteomic approaches can help find new therapeutic targets...
  6. pmc Multiple sequence-directed possibilities provide a pool of nucleosome position choices in different states of activity of a gene
    Vinesh Vinayachandran
    Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Uppal Road, Hyderabad 500007, India
    Epigenetics Chromatin 2:4. 2009
    ....
  7. pmc Chromatin structure and expression of a gene transcribed by RNA polymerase III are independent of H2A.Z deposition
    Aneeshkumar Gopalakrishnan Arimbasseri
    Centre for Cellular and Molecular Biology, Uppal Road, Tarnaka, Hyderabad 500007, India
    Mol Cell Biol 28:2598-607. 2008
    ..Z is not required for establishing the active chromatin structure. These results show that the chromatin structure directly participates in regulation of a Pol III-transcribed gene under different states of its activity in vivo...
  8. ncbi request reprint Positioned nucleosomes due to sequential remodeling of the yeast U6 small nuclear RNA chromatin are essential for its transcriptional activation
    Sushma Shivaswamy
    Centre for Cellular and Molecular Biology, Uppal Road, Tarnaka, Hyderabad 500007, India
    J Biol Chem 281:10461-72. 2006
    ..This two-step remodeling mechanism using the basal factors of the gene yields high transcription levels and generates a chromatin structure similar to that reported for the gene in vivo...
  9. ncbi request reprint The transcriptional activator GAL4-VP16 regulates the intra-molecular interactions of the TATA-binding protein
    Anurag Kumar Mishra
    Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India
    J Biosci 28:423-36. 2003
    ....
  10. ncbi request reprint Nucleosome positioning in relation to nucleosome spacing and DNA sequence-specific binding of a protein
    Rama Haritha Pusarla
    Centre for Cellular and Molecular Biology, Hyderabad, India
    FEBS J 274:2396-410. 2007
    ..The protein-generated boundaries are more effective when more than one binding site is present with a minimum distance of approximately 165 bp, greater than the nucleosome core DNA length, between them...
  11. pmc High-level activation of transcription of the yeast U6 snRNA gene in chromatin by the basal RNA polymerase III transcription factor TFIIIC
    Sushma Shivaswamy
    Centre for Cellular and Molecular Biology, Tarnaka, Hyderabad 500007, India
    Mol Cell Biol 24:3596-606. 2004
    ..Our results suggest that TFIIIC, which is a basal transcription factor of pol III, also plays a direct role in remodeling chromatin on the SNR6 gene...
  12. ncbi request reprint Histones in functional diversification. Core histone variants
    Rama Haritha Pusarla
    Centre for Cellular and Molecular Biology, Tarnaka, Hyderabad, India
    FEBS J 272:5149-68. 2005
    ..A comparison of the status of variants in yeast with those from higher eukaryotes suggests that histone variants have evolved in synchrony with functional requirement of the cell...
  13. pmc A unique nucleosome arrangement, maintained actively by chromatin remodelers facilitates transcription of yeast tRNA genes
    Yatendra Kumar
    Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Uppal Road, Hyderabad 500007, India
    BMC Genomics 14:402. 2013
    ..A prototype tDNA of <150 bp length, is generally considered nucleosome-free while some pol III-transcribed genes have been shown to have nucleosome-positioning properties...
  14. doi request reprint Proteome profile of whole cerebellum of the mature rat
    Devendra Kumar Maurya
    Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Hyderabad, India
    Proteomics 10:4311-9. 2010
    ..The protein sequence data for 31 proteins reported here have been integrated in the UniProt Knowledgebase...
  15. doi request reprint Proteome profile of the mature rat olfactory bulb
    Devendra Kumar Maurya
    Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Hyderabad, India
    Proteomics 9:2593-9. 2009
    ..This includes 24 neuronal activity-specific proteins present at high levels, 7 of which are reported for the first time from OBs...