Murali D Bashyam

Summary

Affiliation: Centre for DNA Fingerprinting and Diagnostics
Country: India

Publications

  1. ncbi request reprint Understanding cancer metastasis: an urgent need for using differential gene expression analysis
    Murali D Bashyam
    Centre for DNA Fingerprinting and Diagnostics, Nacharam, Hyderabad, India
    Cancer 94:1821-9. 2002
  2. ncbi request reprint Molecular genetics of familial hypertrophic cardiomyopathy (FHC)
    Murali D Bashyam
    Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics CDFD, Nacharam, Hyderabad 500076, India
    J Hum Genet 48:55-64. 2003
  3. doi request reprint A low prevalence of MYH7/MYBPC3 mutations among familial hypertrophic cardiomyopathy patients in India
    Murali D Bashyam
    Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics CDFD, Nampally, Hyderabad, India
    Mol Cell Biochem 360:373-82. 2012
  4. pmc A p.R870H mutation in the beta-cardiac myosin heavy chain 7 gene causes familial hypertrophic cardiomyopathy in several members of an Indian family
    Murali D Bashyam
    Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics CDFD, Nacharam, India
    Can J Cardiol 23:788-90. 2007
  5. doi request reprint Phenylalanine hydroxylase gene mutations in phenylketonuria patients from India: identification of novel mutations that affect PAH RNA
    Murali D Bashyam
    Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
    Mol Genet Metab 100:96-9. 2010
  6. ncbi request reprint Studies on nonsense mediated decay reveal novel therapeutic options for genetic diseases
    Murali D Bashyam
    Laboratory of Molecular Oncology and National Genomics and Transcriptomics Facility, Centre for DNA Fingerprinting and Diagnostics, Nacharam, Hyderabad 500 076, India
    Recent Pat DNA Gene Seq 3:7-15. 2009
  7. ncbi request reprint The extracytoplasmic function sigma factors: role in bacterial pathogenesis
    Murali D Bashyam
    Department of Pathology, CCSR 3240, 269 Campus Drive, Stanford University School of Medicine, Stanford, CA 94306, USA
    Infect Genet Evol 4:301-8. 2004
  8. ncbi request reprint The IVS-II-837 (T>G) appears to be a relatively common 'rare' β-globin gene mutation in β-thalassemia patients in Karnataka State, South India
    Murali D Bashyam
    Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics, Nampally, Hyderabad 500001, India
    Hemoglobin 36:497-503. 2012
  9. doi request reprint Molecular genetic analysis of MSUD from India reveals mutations causing altered protein truncation affecting the C-termini of E1α and E1β
    Murali D Bashyam
    Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
    J Cell Biochem 113:3122-32. 2012
  10. pmc Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer
    Murali D Bashyam
    Department of Pathology, Stanford University, Stanford, CA, USA
    Neoplasia 7:556-62. 2005

Detail Information

Publications10

  1. ncbi request reprint Understanding cancer metastasis: an urgent need for using differential gene expression analysis
    Murali D Bashyam
    Centre for DNA Fingerprinting and Diagnostics, Nacharam, Hyderabad, India
    Cancer 94:1821-9. 2002
    ..Recently, several technologies have been developed for analyzing differential gene expression. The current review discusses the importance of these technologies in the molecular analyses of metastasis...
  2. ncbi request reprint Molecular genetics of familial hypertrophic cardiomyopathy (FHC)
    Murali D Bashyam
    Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics CDFD, Nacharam, Hyderabad 500076, India
    J Hum Genet 48:55-64. 2003
    ..How each mutation results in hypertrophy and/or myofibrillar disarray is unclear. The present review discusses the current status of the molecular genetic characterization of this important disorder...
  3. doi request reprint A low prevalence of MYH7/MYBPC3 mutations among familial hypertrophic cardiomyopathy patients in India
    Murali D Bashyam
    Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics CDFD, Nampally, Hyderabad, India
    Mol Cell Biochem 360:373-82. 2012
    ..The study has revealed a greater frequency of occurrence of MYBPC3 mutations when compared to MYH7 mutations...
  4. pmc A p.R870H mutation in the beta-cardiac myosin heavy chain 7 gene causes familial hypertrophic cardiomyopathy in several members of an Indian family
    Murali D Bashyam
    Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics CDFD, Nacharam, India
    Can J Cardiol 23:788-90. 2007
    ..The results indicate that the disease phenotype varied among various affected members of the family, and the variation may be attributed to factors, such as gender and gene dosage...
  5. doi request reprint Phenylalanine hydroxylase gene mutations in phenylketonuria patients from India: identification of novel mutations that affect PAH RNA
    Murali D Bashyam
    Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
    Mol Genet Metab 100:96-9. 2010
    ..This is probably the first report of PKU caused by the activation of NMD...
  6. ncbi request reprint Studies on nonsense mediated decay reveal novel therapeutic options for genetic diseases
    Murali D Bashyam
    Laboratory of Molecular Oncology and National Genomics and Transcriptomics Facility, Centre for DNA Fingerprinting and Diagnostics, Nacharam, Hyderabad 500 076, India
    Recent Pat DNA Gene Seq 3:7-15. 2009
    ..In this review the molecular basis for NMD and attempts to treat genetic diseases which result from NMD are discussed...
  7. ncbi request reprint The extracytoplasmic function sigma factors: role in bacterial pathogenesis
    Murali D Bashyam
    Department of Pathology, CCSR 3240, 269 Campus Drive, Stanford University School of Medicine, Stanford, CA 94306, USA
    Infect Genet Evol 4:301-8. 2004
    ..The present review attempts to highlight the important role played by ECF sigma factors in bacterial pathogenesis and highlights several areas of future study involving the genetics of ECF sigma factors vis-à-vis bacterial pathogenesis...
  8. ncbi request reprint The IVS-II-837 (T>G) appears to be a relatively common 'rare' β-globin gene mutation in β-thalassemia patients in Karnataka State, South India
    Murali D Bashyam
    Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics, Nampally, Hyderabad 500001, India
    Hemoglobin 36:497-503. 2012
    ..This is the first report of the identification of β-thal trait through HPLC-based diabetes screening in India, revealing the importance of linking diabetes screening with screening for thalassemia...
  9. doi request reprint Molecular genetic analysis of MSUD from India reveals mutations causing altered protein truncation affecting the C-termini of E1α and E1β
    Murali D Bashyam
    Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India
    J Cell Biochem 113:3122-32. 2012
    ..Our study has therefore revealed that BCKDHA and BCKDHB mutations might be primarily responsible for MSUD in the Indian population...
  10. pmc Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer
    Murali D Bashyam
    Department of Pathology, Stanford University, Stanford, CA, USA
    Neoplasia 7:556-62. 2005
    ..Our findings suggest candidate genes and pathways, which may contribute to the development or progression of pancreatic cancer...