Affiliation: Central Institute of Medicinal and Aromatic Plants
- Liquiritigenin derivatives and their hepatotoprotective activityRashmi Gaur
Central Institute of Medicinal and Aromatic Plants, P O CIMAP, Lucknow 226015, India
Nat Prod Commun 5:1243-6. 2010..05) when compared with the GalN/LPS group. The results revealed that isoliquiritigenin exhibited better hepatoprotective activity than liquiritigenin and its derivatives...
- Influence of Moringa oleifera on pharmacokinetic disposition of rifampicin using HPLC-PDA method: a pre-clinical studyAnirban Pal
Division of Molecular Bioprospection, Central Institute of Medicinal and Aromatic Plants, CSIR, Lucknow, India
Biomed Chromatogr 25:641-5. 2011..In conclusion, the result of this study suggested that the bioavailability-enhancing property of MoAF may help to lower the dosage level and shorten the treatment course of rifampicin...
- Tricyclic sesquiterpenes from Vetiveria zizanoides (L.) Nash as antimycobacterial agentsGaurav R Dwivedi
Biotechnology Division, CSIR Central Institute of Medicinal and Aromatic Plants Council of Scientific and Industrial Research, P O CIMAP, Lucknow, Uttar Pradesh, 226 015, India
Chem Biol Drug Des 82:587-94. 2013..Finally, compound 2 was found safe at the highest dose of 2000 mg/kg body weight. Being edible, fragrant natural products, 1 and 2 will have advantage over the existing synthetic drugs...
- In vivo efficacy and synergistic interaction of 16α-hydroxycleroda-3, 13 (14) Z-dien-15, 16-olide, a clerodane diterpene from Polyalthia longifolia against methicillin-resistant Staphylococcus aureusVivek Kumar Gupta
CSIR Central Institute of Medicinal and Aromatic Plants, P O CIMAP, Lucknow, 226 015, India
Appl Microbiol Biotechnol 97:9121-31. 2013..In infected mice, CD significantly (P < 0.001) lowered the systemic microbial load in blood, liver, kidney, lung and spleen tissues and did not exhibit any significant toxicity at 100 mg/kg body weight...
- Bioactivity guided isolation of antipsychotic constituents from the leaves of Rauwolfia tetraphylla LShikha Gupta
Medicinal Chemistry Department, Bioprospection Division, Central Institute of Medicinal and Aromatic Plants, Lucknow, India
Fitoterapia 83:1092-9. 2012..The isolated alkaloids, 3-6 could serve as a promising lead structure for drug development of treating psychotic conditions in human...
- In Silico and In Vivo Anti-Malarial Studies of 18β Glycyrrhetinic Acid from Glycyrrhiza glabraKomal Kalani
Medicinal Chemistry Department, CSIR Central Institute of Medicinal and Aromatic Plants, Lucknow, Uttar Pradesh, India
PLoS ONE 8:e74761. 2013..5-250mg/kg on day 8. To the best of our knowledge this is the first ever report on the anti-malarial potential of GA. Further work on optimization of the anti-malarial lead is under progress. ..
- Anticancer activity, toxicity and pharmacokinetic profile of an indanone derivativeDebabrata Chanda
Central Institute of Medicinal and Aromatic Plants, Lucknow, UP, India
Eur J Pharm Sci 47:988-95. 2012..Pharmacokinetic studies in rabbits revealed rate of absorption, half life, volume of distribution with high plasma and blood clearance after i.v. administration. Indanone 1, is a safe and moderately active anticancer agent...
- Antiplasmodial activity of artecyclopentyl mether a new artemisinin derivative and its effect on pathogenesis in Plasmodium yoelii nigeriensis infected miceJyoti Agarwal
Central Institute of Medicinal and Aromatic Plants, CSIR, P O CIMAP, 226015 Lucknow, India
Parasitol Res 109:1003-8. 2011..76-95.43%), lipid peroxidation (59.30-76.05%) and glycaemic data (62.70-76.66%). The results indicate the potentiality of the new derivative as an antimalarial against asexual stages of the parasite...
- Synergistic effect of silymarin and standardized extract of Phyllanthus amarus against CCl4-induced hepatotoxicity in Rattus norvegicusNarayan P Yadav
In Vivo Testing Facility, Genetic Resources and Biotechnology Division, Central Institute of Medicinal and Aromatic Plants, Near Kukrail Picnic Spot, PO CIMAP, Lucknow 226015, India
Phytomedicine 15:1053-61. 2008..amarus showed better activity due to the higher concentration of phyllanthin in ethanolic extract in comparison to aqueous extract of P. amarus as estimated by HPLC...
- Novel anti-inflammatory phytoconstituents from Desmodium gangeticumAkhilesh K Yadav
a Analytical Chemistry Department, CSIR Central Institute of Medicinal and Aromatic Plants, Lucknow, India
Nat Prod Res 27:1639-45. 2013..In addition, compounds 3 and 6 were investigated for their effects on lipopolysaccharide-stimulated macrophages for the production of pro-inflammatory cytokines such as tumour necrosis factor-α and interleukin-6. ..
- Nyctanthes arbor-tristis Linn--a critical ethnopharmacological reviewJyoti Agrawal
In Vivo Testing Facility, Molecular Bio prospection Department, Central Institute of Medicinal and Aromatic Plants, Council of Scientific and Industrial Research, Lucknow 226015, India
J Ethnopharmacol 146:645-58. 2013..Vitally, the natives plant it in their home gardens to pass on its medicinal usage to oncoming generations...