Ranju Bansal

Summary

Country: India

Publications

  1. doi request reprint FT-IR method development and validation for quantitative estimation of zidovudine in bulk and tablet dosage form
    R Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
    Drug Res (Stuttg) 63:165-70. 2013
  2. doi request reprint Synthesis and antileukemic activity of 16E-[4-(2-carboxy)ethoxybenzylidene]-androstene amides
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160 014, India
    Steroids 77:552-7. 2012
  3. doi request reprint Synthesis and aromatase inhibitory activity of some new 16E-arylidenosteroids
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Sector 14, Panjab University, Chandigarh 160 014, India
    Bioorg Chem 45:36-40. 2012
  4. doi request reprint Synthesis and anticonvulsant activity of O-alkylated derivatives of 1-(2-naphthyl)-2-(imidazol-1-yl)ethanone oxime
    R Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
    Arzneimittelforschung 62:420-4. 2012
  5. doi request reprint Design, synthesis and evaluation of novel 16-imidazolyl substituted steroidal derivatives possessing potent diversified pharmacological properties
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Sector 14, Panjab University, Chandigarh 160014, India
    Steroids 77:621-9. 2012
  6. doi request reprint Synthesis of a new series of 1H-imidazol-1-yl substituted 8-phenylxanthines as adenosine receptor ligands
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    Chem Biodivers 8:1290-300. 2011
  7. ncbi request reprint Synthesis and biological evaluation of 16E-arylidenosteroids as cytotoxic and anti-aromatase agents
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Sector 14, Panjab University, Chandigarh, India
    Chem Pharm Bull (Tokyo) 59:327-31. 2011
  8. doi request reprint Synthesis of quaternary ammonium salts of 16E-[4-(2-alkylaminoethoxy)-3-methoxybenzylidene]androstene derivatives as skeletal muscle relaxants
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
    Steroids 76:254-60. 2011
  9. doi request reprint Synthesis and antineoplastic activity of O-alkylated derivatives of 7-hydroximinoandrost-5-ene steroids
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Sector 14, Panjab University, Chandigarh, India
    Arch Pharm (Weinheim) 343:377-83. 2010
  10. doi request reprint Synthesis and vasodilatory activity of some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Sector 14, Chandigarh 160014, India
    Eur J Med Chem 44:4441-7. 2009

Collaborators

Detail Information

Publications21

  1. doi request reprint FT-IR method development and validation for quantitative estimation of zidovudine in bulk and tablet dosage form
    R Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
    Drug Res (Stuttg) 63:165-70. 2013
    ....
  2. doi request reprint Synthesis and antileukemic activity of 16E-[4-(2-carboxy)ethoxybenzylidene]-androstene amides
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160 014, India
    Steroids 77:552-7. 2012
    ..94, 2.61, 6.90 and 1.79μM against CCRF-CEM, K-562, RPMI-8226 and SR leukemia cell lines, respectively...
  3. doi request reprint Synthesis and aromatase inhibitory activity of some new 16E-arylidenosteroids
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Sector 14, Panjab University, Chandigarh 160 014, India
    Bioorg Chem 45:36-40. 2012
    ..2 μM) and 16-(benzo-[1,3]dioxol-5-ylmethylene)androsta-1,4-diene-3,17-dione (11, IC(50): 6.4 μM) were found to be approximately five times more potent in comparison to aminoglutethimide...
  4. doi request reprint Synthesis and anticonvulsant activity of O-alkylated derivatives of 1-(2-naphthyl)-2-(imidazol-1-yl)ethanone oxime
    R Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
    Arzneimittelforschung 62:420-4. 2012
    ..Anticonvulsant activity of the compounds was determined against pentylenetetrazole induced convulsions in mice. The newly synthesized compounds exhibited moderate to significant activity compared to diazepam...
  5. doi request reprint Design, synthesis and evaluation of novel 16-imidazolyl substituted steroidal derivatives possessing potent diversified pharmacological properties
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Sector 14, Panjab University, Chandigarh 160014, India
    Steroids 77:621-9. 2012
    ..9 μm)...
  6. doi request reprint Synthesis of a new series of 1H-imidazol-1-yl substituted 8-phenylxanthines as adenosine receptor ligands
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    Chem Biodivers 8:1290-300. 2011
    ..The xanthine derivatives displayed varying degrees of affinity and selectivity towards A(1) and A(2A) receptor subtypes despite a common but variedly substituted Ar-C(8)...
  7. ncbi request reprint Synthesis and biological evaluation of 16E-arylidenosteroids as cytotoxic and anti-aromatase agents
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Sector 14, Panjab University, Chandigarh, India
    Chem Pharm Bull (Tokyo) 59:327-31. 2011
    ....
  8. doi request reprint Synthesis of quaternary ammonium salts of 16E-[4-(2-alkylaminoethoxy)-3-methoxybenzylidene]androstene derivatives as skeletal muscle relaxants
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
    Steroids 76:254-60. 2011
    ..Some of the compounds also inhibited acetylcholinesterase activity in low concentrations so that they would not be directly suitable for use as muscle relaxants...
  9. doi request reprint Synthesis and antineoplastic activity of O-alkylated derivatives of 7-hydroximinoandrost-5-ene steroids
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Sector 14, Panjab University, Chandigarh, India
    Arch Pharm (Weinheim) 343:377-83. 2010
    ..However, the imidazolyl-substituted steroidal oxime ethers displayed moderate inhibition of cytochrome P450 aromatase...
  10. doi request reprint Synthesis and vasodilatory activity of some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Sector 14, Chandigarh 160014, India
    Eur J Med Chem 44:4441-7. 2009
    ..The most active compound 6-[4-(2-oxo-2-pyrrolidin-1-yl-ethoxy)phenyl]-2-(4-fluorophenyl)-4,5-dihydropyridazin-3(2H)-one (11) exhibited vasodilating activity in nanomolar range (IC(50)=0.051 microM)...
  11. ncbi request reprint Synthesis and evaluation of a dimer of 2-(4-pyridylmethyl)-1-indanone as a novel nonsteroidal aromatase inhibitor
    Ranju Gupta
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
    Arch Pharm (Weinheim) 337:398-401. 2004
    ..The dimer showed strong inhibition of human placental aromatase and was found 3 times more potent (RP = 3, IC(50) = 10.2 microM) as compared to aminoglutethimide (RP = 1, IC(50) = 18.5 microM...
  12. ncbi request reprint Corticosteroids: the mainstay in asthma therapy
    Ranju Gupta
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    Bioorg Med Chem 12:6331-42. 2004
    ....
  13. ncbi request reprint An update on cyclic nucleotide phosphodiesterase (PDE) inhibitors: phosphodiesterases and drug selectivity
    R Gupta
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    Methods Find Exp Clin Pharmacol 27:101-18. 2005
    ..This review details many key aspects of multiple forms of PDEs and their inhibitors with diversified chemical structures, which can act as leads for synthesis of novel drugs...
  14. doi request reprint Synthesis of 8-(cyclopentyloxy)phenyl substituted xanthine derivatives as adenosine A2A ligands
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    Arzneimittelforschung 60:131-6. 2010
    ....
  15. doi request reprint Synthesis of 16E-[3-methoxy-4-(2-aminoethoxy)benzylidene]androstene derivatives as potent cytotoxic agents
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    Steroids 73:1391-9. 2008
    ....
  16. ncbi request reprint Synthesis and study of some new N-substituted imide derivatives as potential anticancer agents
    Dharam Paul Jindal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    Farmaco 60:283-90. 2005
    ..These compounds (37-39) have exhibited weak inhibition of human placental aromatase as compared to aminoglutethimide...
  17. doi request reprint Synthesis of a series of 8-(substituted-phenyl)xanthines and a study on the effects of substitution pattern of phenyl substituents on affinity for adenosine A(1) and A(2A) receptors
    Ranju Bansal
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    Eur J Med Chem 44:2122-7. 2009
    ..It has been observed that substitution pattern on 8-phenyl group greatly affects the affinity and selectivity at adenosine receptors, with A(2A) tolerating bulkier substituents than did A(1) receptors...
  18. doi request reprint Synthesis and evaluation of 2-substituted-6-phenyl-4,5-dihydropyridazin-3(2H)-ones as potent inodilators
    Dinesh Kumar
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    Acta Pharm 58:393-405. 2008
    ..6-(4-Methanesulfonamidophenyl)-2-phenyl-4,5-dihydropyridazin-3(2H)-one (7) exhibited significant inodilatory properties and showed vasorelaxant activity in a nanomolar range (IC50 = 0.08 +/- 0.01 mumol L-1)...
  19. doi request reprint Synthesis and antiproliferative activity of some androstene oximes and their o-alkylated derivatives
    Pratap Chandra Acharya
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India
    Arch Pharm (Weinheim) 347:193-9. 2014
    ..The oximes and oxime ethers were found to have moderate to good antiproliferative activity against various leukemia, colon, melanoma, and renal cancer cell lines. ..
  20. doi request reprint Novel 8-(p-substituted-phenyl/benzyl)xanthines with selectivity for the A2A adenosine receptor possess bronchospasmolytic activity
    Rakesh Yadav
    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India
    Eur J Med Chem 75:327-35. 2014
    ..Replacement of phenyl ring with benzyl moiety at C8 of xanthine skeleton resulted in notable reduction in adenosine receptor affinity and broncholytic effects. ..
  21. ncbi request reprint Synthesis and bronchodilatory activity of some nitrogen bridgehead compounds
    Dharam Paul Jindal
    University Institute of Pharmaceutical Sciences formerly Department of Pharmaceutical Sciences, Panjab University, Chandigarh 160 014, India
    Eur J Med Chem 37:419-25. 2002
    ..This resulted in loss of relaxation activity in precontracted guinea pig tracheal chain. These results show that the better relaxation property possessed by compound 7 hydrochloride is due to methoxy groups at 8 and 9 positions...