Surendra K Sharma

Summary

Affiliation: All India Institute of Medical Sciences
Country: India

Publications

  1. ncbi request reprint Radiological manifestations of splenic tuberculosis: a 23-patient case series from India
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi
    Indian J Med Res 125:669-78. 2007
  2. pmc Medical management of genitourinary tuberculosis
    Tamilarasu Kadhiravan
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 608, India
    Indian J Urol 24:362-8. 2008
  3. pmc A study of empyema thoracis and role of intrapleural streptokinase in its management
    Amit Banga
    Department of Medicine, All India Institute of Medical Science, New Delhi 110029, India
    BMC Infect Dis 4:19. 2004
  4. ncbi request reprint Reversal of subclinical adrenal insufficiency through antituberculosis treatment in TB patients: a longitudinal follow up
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Indian J Med Res 122:127-31. 2005
  5. ncbi request reprint Obesity, and not obstructive sleep apnea, is responsible for increased serum hs-CRP levels in patients with sleep-disordered breathing in Delhi
    S K Sharma
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Sleep Med 9:149-56. 2008
  6. ncbi request reprint Miliary tuberculosis: new insights into an old disease
    Surendra Kumar Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Lancet Infect Dis 5:415-30. 2005
  7. ncbi request reprint HIV-TB co-infection: epidemiology, diagnosis & management
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
    Indian J Med Res 121:550-67. 2005
  8. ncbi request reprint Pleural fluid interferon-gamma and adenosine deaminase levels in tuberculosis pleural effusion: a cost-effectiveness analysis
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Clin Lab Anal 19:40-6. 2005
  9. ncbi request reprint Bilateral adrenal abscesses and skin lesions in an immunocompetent patient
    S K Sharma
    Department of Medicine, India Institute of Medical Sciences, New Delhi, India
    Lancet Infect Dis 5:126. 2005
  10. pmc Prevalence of multidrug-resistant tuberculosis among newly diagnosed cases of sputum-positive pulmonary tuberculosis
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 133:308-11. 2011

Collaborators

Detail Information

Publications124 found, 100 shown here

  1. ncbi request reprint Radiological manifestations of splenic tuberculosis: a 23-patient case series from India
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi
    Indian J Med Res 125:669-78. 2007
    ..The range of radiological manifestations of splenic TB is poorly described. Here, we review the ultrasonographic and computed tomographic (CT) images of 23 cases from two large tertiary care centers in India...
  2. pmc Medical management of genitourinary tuberculosis
    Tamilarasu Kadhiravan
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 608, India
    Indian J Urol 24:362-8. 2008
    ..Standardized treatment regimens at correct doses and assured completion of treatment have made DOTS the present-day standard of care for the management of all forms of TB including GUTB...
  3. pmc A study of empyema thoracis and role of intrapleural streptokinase in its management
    Amit Banga
    Department of Medicine, All India Institute of Medical Science, New Delhi 110029, India
    BMC Infect Dis 4:19. 2004
    ..The present study was carried out to describe the clinical profile and outcome of patients with empyema thoracis including those with chronic empyema and to study the efficacy and safety of intrapleural streptokinase in its management...
  4. ncbi request reprint Reversal of subclinical adrenal insufficiency through antituberculosis treatment in TB patients: a longitudinal follow up
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Indian J Med Res 122:127-31. 2005
    ..We studied the effect of antituberculosis treatment (ATT) with respect to reversal of the adrenal insufficiency, as assessed by response to standard dose adrenocorticotropin (ACTH) stimulation test in TB patients...
  5. ncbi request reprint Obesity, and not obstructive sleep apnea, is responsible for increased serum hs-CRP levels in patients with sleep-disordered breathing in Delhi
    S K Sharma
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Sleep Med 9:149-56. 2008
    ..The present study was conducted to evaluate serum levels of high-sensitivity C-reactive protein (hs-CRP) in newly diagnosed patients with obstructive sleep apnea (OSA)...
  6. ncbi request reprint Miliary tuberculosis: new insights into an old disease
    Surendra Kumar Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Lancet Infect Dis 5:415-30. 2005
    ..Although response to first-line antituberculosis drugs is good, evidence regarding optimum duration of treatment is lacking and the role of adjunctive corticosteroid treatment is unclear...
  7. ncbi request reprint HIV-TB co-infection: epidemiology, diagnosis & management
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
    Indian J Med Res 121:550-67. 2005
    ..Timely institution of antituberculosis treatment using the directly observed treatment, short-course (DOTS) strategy and HAART markedly improves the outcome of HIV-infected patients with TB...
  8. ncbi request reprint Pleural fluid interferon-gamma and adenosine deaminase levels in tuberculosis pleural effusion: a cost-effectiveness analysis
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Clin Lab Anal 19:40-6. 2005
    ..In developing countries, where TB is rampant and cost is a major concern, pleural fluid IFN-gamma estimation does not seem to be a cost-effective investigation method for differentiating TB from non-TB pleural effusion...
  9. ncbi request reprint Bilateral adrenal abscesses and skin lesions in an immunocompetent patient
    S K Sharma
    Department of Medicine, India Institute of Medical Sciences, New Delhi, India
    Lancet Infect Dis 5:126. 2005
  10. pmc Prevalence of multidrug-resistant tuberculosis among newly diagnosed cases of sputum-positive pulmonary tuberculosis
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 133:308-11. 2011
    ..We sought to ascertain the prevalence of MDR-TB among new cases of sputum-positive pulmonary TB...
  11. ncbi request reprint A clinical prediction rule to identify patients with tuberculosis at high risk for HIV co-infection
    S K Sharma
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 130:51-7. 2009
    ..We sought to derive and validate a clinical prediction rule, based on clinical and laboratory parameters, to identify patients at high risk for HIV co-infection among those treated for active TB...
  12. ncbi request reprint Multidrug-resistant tuberculosis
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, D II 23, Ansari Nagar, New Delhi 110 029, India
    Indian J Med Res 120:354-76. 2004
    ..In certain areas, currently available programme approach may not be adequate and innovative approaches such as DOTS-plus may have to be employed to effectively control MDR-TB...
  13. ncbi request reprint A study of TB-associated immune reconstitution inflammatory syndrome using the consensus case-definition
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 131:804-8. 2010
    ....
  14. doi request reprint Safety of 3 different reintroduction regimens of antituberculosis drugs after development of antituberculosis treatment-induced hepatotoxicity
    Surendra K Sharma
    Div of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Clin Infect Dis 50:833-9. 2010
    ..Reintroduction of antituberculosis drugs in patients with DIH has never been studied systematically. We aimed to compare the safety of 3 different reintroduction regimens of antituberculosis drugs in patients with antituberculosis DIH...
  15. ncbi request reprint Epidemiology of adult obstructive sleep apnoea syndrome in India
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 131:171-5. 2010
    ..Therefore, future studies on the association of OSA and metabolic syndrome should carefully evaluate confounding effect of obesity on metabolic abnormalities in patients with OSA...
  16. ncbi request reprint Effect of antituberculosis treatment on cardiopulmonary responses to exercise in miliary tuberculosis
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 124:411-8. 2006
    ..Tuberculosis (TB) is a major health problem in the developing world. In this preliminary study, we report the effect of antituberculosis treatment (ATT) on cardiopulmonary responses to exercise in patients with miliary tuberculosis (MTB)...
  17. ncbi request reprint Obesity, and not obstructive sleep apnea, is responsible for metabolic abnormalities in a cohort with sleep-disordered breathing
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Sleep Med 8:12-7. 2007
    ..To assess the profile of metabolic abnormalities in subjects with obstructive sleep apnea (OSA)...
  18. ncbi request reprint Validation of the modified Berlin questionnaire to identify patients at risk for the obstructive sleep apnoea syndrome
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 124:281-90. 2006
    ..The present study was undertaken to test the utility of modified Berlin questionnaire for risk categorization of OSA in Indian setting...
  19. ncbi request reprint Multidrug-resistant tuberculosis: a menace that threatens to destabilize tuberculosis control
    Surendra K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Chest 130:261-72. 2006
    ..With newer effective anti-TB drugs still a distant dream, innovative approaches such as DOTS-Plus are showing promise for the management of patients with MDR-TB under program conditions and appear to be a hope for future...
  20. ncbi request reprint Prevalence and risk factors of obstructive sleep apnea syndrome in a population of Delhi, India
    Surendra Kumar Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 11029, India
    Chest 130:149-56. 2006
    ..The study was performed to assess the prevalence and risk factors of OSA in a semi-urban Indian population...
  21. ncbi request reprint Diagnostic accuracy of ascitic fluid IFN-gamma and adenosine deaminase assays in the diagnosis of tuberculous ascites
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Interferon Cytokine Res 26:484-8. 2006
    ..Because both material and human costs of the ADA assay are far less than those of the IFN-gamma assay, the former is probably the most appropriate diagnostic test for analysis of peritoneal fluid in resource- limited settings...
  22. pmc Outcomes of antiretroviral therapy in a northern Indian urban clinic
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India
    Bull World Health Organ 88:222-6. 2010
    ..However, whether they would succeed as part of a national programme in a resource-constrained setting such as India is not clear. The outcomes and specific problems encountered in such a setting have not been adequately studied...
  23. ncbi request reprint Prediction of obstructive sleep apnea in patients presenting to a tertiary care center
    S K Sharma
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Sleep Breath 10:147-54. 2006
    ..7, 89.1, and 84.5%, respectively. BMI, male gender, SI, and ChI are independent predictors of OSA. Diagnostic model derived from these parameters is useful for predicting presence of OSA and screening subjects for PSG...
  24. ncbi request reprint Predictors of development and outcome in patients with acute respiratory distress syndrome due to tuberculosis
    S K Sharma
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, All India Institute of Medical Sciences, New Delhi, India
    Int J Tuberc Lung Dis 10:429-35. 2006
    ..To study the predictors of development and determinants of outcome in patients with acute respiratory distress syndrome (ARDS) due to tuberculosis (TB)...
  25. ncbi request reprint Progress of DOTS in global tuberculosis control
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Lancet 367:951-2. 2006
  26. ncbi request reprint Extrapulmonary tuberculosis
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, D II 23, Ansari Nagar, New Delhi 110 029, India
    Indian J Med Res 120:316-53. 2004
    ..Further research is required for evolving the most suitable treatment regimens, optimal duration of treatment and safety when used with highly active antiretroviral treatment (HAART)...
  27. ncbi request reprint DOTS centre at a tertiary care teaching hospital: lessons learned and future directions
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Chest Dis Allied Sci 46:251-6. 2004
    ..In this communication, we describe the experience of establishing a DOTS centre at India's premier medical institute and discuss the lessons learned...
  28. ncbi request reprint A young man with rectal polyps
    S K Sharma
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, All India Institute of Medical Sciences, New Delhi, India
    Lancet Infect Dis 4:556. 2004
  29. ncbi request reprint Prevalence of extensively drug-resistant tuberculosis among patients with multidrug-resistant tuberculosis: a retrospective hospital-based study
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 130:392-5. 2009
    ..High rates of XDR-TB have been reported from India. We sought to ascertain the prevalence of XDR-TB among patients with MDR-TB treated at a tertiary care centre in New Delhi, India...
  30. pmc Prevalence of multidrug-resistant tuberculosis among category II pulmonary tuberculosis patients
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 133:312-5. 2011
    ..We carried out this study to ascertain the prevalence of MDR-TB among category II pulmonary TB patients...
  31. ncbi request reprint Spontaneous splenic rupture in dengue hemorrhagic fever
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Am J Trop Med Hyg 78:7. 2008
  32. ncbi request reprint Increasing HIV seropositivity among adult tuberculosis patients in Delhi
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Indian J Med Res 117:239-42. 2003
    ..4 per cent (2 of 500 patients). This communication describes a dramatic increase in seropositivity and highlights the importance of continued HIV serosurveillance in patients with TB...
  33. doi request reprint Prevalence and risk factors for wheezing in children from rural areas of north India
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Allergy Asthma Proc 28:647-53. 2007
    ....
  34. ncbi request reprint A prospective study of risk factor profile & incidence of deep venous thrombosis among medically-ill hospitalized patients at a tertiary care hospital in northern India
    Surendra K Sharma
    Division of Pulmonary, Critical Care and Sleep Medicine, Head, Department of Medicine All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110 029, India
    Indian J Med Res 130:726-30. 2009
    ..However, there are no published data from India addressing at this issue. We sought to study the risk factor profile and the incidence of DVT among hospitalized medically-ill patients, a tertiary care hospital in northern India...
  35. pmc Poor follow-up rates at a self-pay northern Indian tertiary AIDS clinic
    Duncan Smith Rohrberg Maru
    AIDS Program, Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, 11029, India
    Int J Equity Health 6:14. 2007
    ..The vast majority of patients, however, remain without access to free medicines...
  36. ncbi request reprint Antituberculosis drugs and hepatotoxicity
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Infect Genet Evol 4:167-70. 2004
  37. ncbi request reprint Diagnostic utility of pleural fluid IFN-gamma in tuberculosis pleural effusion
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    J Interferon Cytokine Res 24:213-7. 2004
    ..2%, 97.3%, 85.7%, and 98.3%, respectively. Estimation of IFN-gamma levels in pleural fluid is a useful diagnostic modality for TB pleural effusion. A cutoff of 138 pg/ml provides the best sensitivity and specificity for diagnosis of TB...
  38. pmc Spectrum of clinical disease in a series of 135 hospitalised HIV-infected patients from north India
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    BMC Infect Dis 4:52. 2004
    ..The objective of this study was to document the spectrum and determine the frequency of various opportunistic infections (OIs) and non-infectious opportunistic diseases, in hospitalised HIV-infected patients from north India...
  39. ncbi request reprint A stepped approach for prediction of obstructive sleep apnea in overtly asymptomatic obese subjects: a hospital based study
    S K Sharma
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Sleep Med 5:351-7. 2004
    ..Polysomnography (PSG) is a costly and time-consuming investigation. Since it is not feasible to subject all obese individuals to PSG, it is useful to define predictors of OSA among these subjects...
  40. ncbi request reprint Sarcoidosis: global scenario & Indian perspective
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Indian J Med Res 116:221-47. 2002
    ..Sometimes steroid-sparing alternative treatments may be beneficial. In this review, the current understanding of the global scenario and Indian perspective of sarcoidosis are critically reviewed...
  41. ncbi request reprint Evaluation of risk factors for antituberculosis treatment induced hepatotoxicity
    Rohit Singla
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 132:81-6. 2010
    ..We undertook a prospective case-control study to assess the role of these putative risk factors in the development of DIH in patients receiving anti-TB treatment...
  42. ncbi request reprint Prevalence and risk factors of syndrome Z in urban Indians
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Sleep Med 11:562-8. 2010
    ..Syndrome Z is defined as the co-occurrence of obstructive sleep apnea (OSA) and metabolic syndrome. There is a paucity of information on the magnitude of syndrome Z in the community and the factors associated with it...
  43. pmc Efficacy and safety of thrice weekly DOTS in tuberculosis patients with and without HIV co-infection: an observational study
    Richa Vashishtha
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    BMC Infect Dis 13:468. 2013
    ..The present study sets out to compare TB treatment outcomes in these two groups in the Indian national programme, which currently involves thrice-weekly therapy for all, regardless of HIV status...
  44. ncbi request reprint Human leukocyte antigen-DR alleles influence the clinical course of pulmonary sarcoidosis in Asian Indians
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Am J Respir Cell Mol Biol 29:225-31. 2003
    ..The present findings imply that HLA-associated genetic factors influence the risk for the development of sarcoidosis and disease progression...
  45. ncbi request reprint Prevalence and risk factors of obstructive sleep apnea among middle-aged urban Indians: a community-based study
    Emmadi V Reddy
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Sleep Med 10:913-8. 2009
    ..The epidemiology of obstructive sleep apnea (OSA) and obstructive sleep apnea syndrome (OSAS) is not well studied among Indians. We sought to determine the prevalence and risk factors of OSA in a middle-aged urban Indian population...
  46. pmc Clinical characteristics of tuberculosis-associated immune reconstitution inflammatory syndrome in North Indian population of HIV/AIDS patients receiving HAART
    Suman Karmakar
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Clin Dev Immunol 2011:239021. 2011
    ..The present study was undertaken to describe the pattern of TB-associated IRIS using recently proposed consensus case-definitions for TB-IRIS for its use in resource-limited settings...
  47. doi request reprint Recruitment of Th1 effector cells in human tuberculosis: hierarchy of chemokine receptor(s) and their ligands
    Pradip K Saha
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Cytokine 63:43-51. 2013
    ..In vitro chemotaxis assay indicates dominant role of RANTES and IP-10 in the selective recruitment of CXCR3(+)CCR5(+)cells at the tubercular pathologic sites...
  48. pmc Comparative evaluation of GenoType MTBDRplus line probe assay with solid culture method in early diagnosis of multidrug resistant tuberculosis (MDR-TB) at a tertiary care centre in India
    Raj N Yadav
    Department of Internal Medicine Division of Research for Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India
    PLoS ONE 8:e72036. 2013
    ....
  49. doi request reprint CPAP for the metabolic syndrome in patients with obstructive sleep apnea
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    N Engl J Med 365:2277-86. 2011
    ..It is unclear whether treatment of obstructive sleep apnea syndrome with continuous positive airway pressure (CPAP) would modify these outcomes...
  50. pmc Prevalence of metabolic syndrome in a north Indian hospital-based population with obstructive sleep apnoea
    Swastik Agrawal
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 134:639-44. 2011
    ..We investigated the prevalence of MS and its components in a cross-sectional study in patients with and without OSA in a hospital-based population of a tertiary health care centre in New Delhi, India...
  51. ncbi request reprint Are metabolic syndrome, obstructive sleep apnoea & syndrome Z sequential?--a hypothesis
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 131:455-8. 2010
    ....
  52. doi request reprint FoxP3+ regulatory T cells suppress effector T-cell function at pathologic site in miliary tuberculosis
    Prabhat K Sharma
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    Am J Respir Crit Care Med 179:1061-70. 2009
    ....
  53. pmc Early versus delayed initiation of antiretroviral therapy for Indian HIV-Infected individuals with tuberculosis on antituberculosis treatment
    Sanjeev Sinha
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India
    BMC Infect Dis 12:168. 2012
    ....
  54. pmc Clinical presentation and predictors of outcome in patients with severe acute exacerbation of chronic obstructive pulmonary disease requiring admission to intensive care unit
    Alladi Mohan
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati 517 507, India
    BMC Pulm Med 6:27. 2006
    ..Severe acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) is a common reason for emergency room (ER) visit about which little has been documented from India...
  55. ncbi request reprint Human leukocyte antigen class I supertypes influence susceptibility and severity of tuberculosis
    Arumugam Balamurugan
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India
    J Infect Dis 189:805-11. 2004
    ....
  56. pmc Nevirapine versus efavirenz-based antiretroviral therapy regimens in antiretroviral-naive patients with HIV and tuberculosis infections in India: a pilot study
    Sanjeev Sinha
    Departments of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    BMC Infect Dis 13:482. 2013
    ..Nevirapine is a much cheaper drug than its alternative efavirenz, and might be beneficial in resource constrained settings...
  57. pmc Vitamin D rescues impaired Mycobacterium tuberculosis-mediated tumor necrosis factor release in macrophages of HIV-seropositive individuals through an enhanced Toll-like receptor signaling pathway in vitro
    Asha Anandaiah
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Infect Immun 81:2-10. 2013
    ..tuberculosis disease, supporting a potential role for exogenous vitamin D as a therapeutic adjuvant in M. tuberculosis infection in HIV(+) persons...
  58. pmc Challenges in the diagnosis & treatment of miliary tuberculosis
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 135:703-30. 2012
    ..However, sparse data are available from randomized controlled trials to define the optimum regimen and duration of treatment in patients with drug-sensitive as well as drug-resistant miliary TB, including those with HIV/AIDS...
  59. ncbi request reprint Cytokine polarization in miliary and pleural tuberculosis
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Clin Immunol 22:345-52. 2002
    ....
  60. ncbi request reprint Thyroxine replacement therapy reverses sleep-disordered breathing in patients with primary hypothyroidism
    Ashish Jha
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Sleep Med 7:55-61. 2006
    ..This study was undertaken to determine the prevalence of SDB and to evaluate the effect of thyroxine replacement therapy on SDB in patients with primary hypothyroidism...
  61. doi request reprint Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Cochrane Database Syst Rev 7:CD007545. 2013
    ..Rifampicin or rifamycin-combination treatments are shorter and may result in higher completion rates...
  62. doi request reprint Delayed resolution of inflammatory response compared with clinical recovery in patients with acute exacerbations of chronic obstructive pulmonary disease
    Anant Mohan
    Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences, New Delhi, India
    Respirology 17:1080-5. 2012
    ..The aim was to assess the changes in levels of inflammatory markers in AECOPD and correlate these with clinical and laboratory indices of recovery...
  63. ncbi request reprint Relevance of latent TB infection in areas of high TB prevalence
    Surendra K Sharma
    Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India
    Chest 142:761-73. 2012
    ..There is ample space for further research in these countries, whose outcomes may strengthen future national guidelines...
  64. pmc Genetic polymorphisms in TNF genes and tuberculosis in North Indians
    Shilpy Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    BMC Infect Dis 10:165. 2010
    ..A number of genes have been identified in studies of diverse origins to be important in tuberculosis. Of these, both tumor necrosis factor alpha (TNF-alpha) and lymphotoxin alpha (LT-alpha) play important immunoregulatory roles...
  65. ncbi request reprint Proton magnetic resonance spectroscopy of brain in obstructive sleep apnoea in north Indian Asian subjects
    Surendra K Sharma
    Departments of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 132:278-86. 2010
    ..The aim of this study was to determine the absolute concentration of cerebral metabolites in apnoeic and non-apnoeic subjects from different regions of the brain to monitor the regional variation of cerebral metabolites...
  66. ncbi request reprint Diagnosis and treatment of tuberculous pleural effusion in 2006
    Arun Gopi
    Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Jonathan Lucas St, Suite 812 CSB, PO Box 250360, Charleston, SC 29426, USA
    Chest 131:880-9. 2007
    ..The treatment of TB pleural effusions in patients with HIV/AIDS is essentially similar to that in HIV-negative patients. At present, evidence regarding the use of corticosteroids in the treatment of TB pleural effusion is not clear-cut...
  67. ncbi request reprint Pattern & correlates of neurocognitive dysfunction in Asian Indian adults with severe obstructive sleep apnoea
    Hanish Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 132:409-14. 2010
    ..No published data are available on neurocognitive dysfunction in Asian Indians with obstructive sleep apnoea (OSA). We therefore, studied the pattern and correlates of neurocognitive dysfunction in Indian adults with severe OSA...
  68. ncbi request reprint A prospective study of sensitivity and specificity of adenosine deaminase estimation in the diagnosis of tuberculosis pleural effusion
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi
    Indian J Chest Dis Allied Sci 43:149-55. 2001
    ..From this study it is concluded that, using 100 IU/L as the cut-off, it is possible to avoid pleural biopsy to ascertain the diagnosis of TB in as much as 40% of the patients...
  69. ncbi request reprint DOTS at a tertiary care center in northern India: successes, challenges and the next steps in tuberculosis control
    Mohammad Tahir
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 123:702-6. 2006
    ..We present a brief report on the status of a DOTS center being run at a large tertiary care center in northern India for almost four years (2001-2005)...
  70. ncbi request reprint Tubercular oesophagocutaneous fistula
    B N Vinodh
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Indian J Chest Dis Allied Sci 48:209-11. 2006
    ..A case of oesophageal tuberculosis complicated by an oesophagocutaneous fistual is reported. We subsequently review the literature of this exceedingly rare condition...
  71. doi request reprint A study of incidence of AKI in critically ill patients
    Mukesh Sharma Paudel
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Ren Fail 34:1217-22. 2012
    ..There are no new studies from the developing countries looking at AKI in these patients since adoption of uniform Acute Kidney Injury Network (AKIN) criteria...
  72. ncbi request reprint Acute lung injury and acute respiratory distress syndrome in malaria
    Alladi Mohan
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati, India
    J Vector Borne Dis 45:179-93. 2008
    ..ARDS in malaria is a disease with a high mortality. Early diagnosis, institution of specific antimalarial treatment and assisted ventilation can be life-saving...
  73. ncbi request reprint Polarized helper T cells in tubercular pleural effusion: phenotypic identity and selective recruitment
    Dipendra K Mitra
    Departments of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Eur J Immunol 35:2367-75. 2005
    ..Findings of the present study provide mechanistic insights into the critical events of T cell trafficking in tuberculosis and may help designing better therapeutic modalities...
  74. doi request reprint Management of the patient with HIV disease
    Surendra K Sharma
    Division of Pulmonary and Critical Care Medicine, All India Institute of Medical Sciences, New Delhi, India
    Dis Mon 54:162-95. 2008
  75. ncbi request reprint HIV seropositivity among adult tuberculosis patients in Delhi
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Chest Dis Allied Sci 42:157-60. 2000
    ..As the HIV infection is making rapid in-roads in India, it is suggested that continuous HIV sero-surveillance should be done in patients with tuberculosis...
  76. ncbi request reprint Persistently high HIV seroprevalence among adult tuberculosis patients at a tertiary care centre in Delhi
    P Piramanayagam
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    Indian J Med Res 125:163-7. 2007
    ..This study was designed to estimate HIV seroprevalence among tuberculosis patients presenting to tertiary care centre in Delhi...
  77. pmc Rare manifestations of sarcoidosis in modern era of new diagnostic tools
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 135:621-9. 2012
    ..We sought to study the rare clinical and radiological manifestations (<5%) in patients with sarcoidosis...
  78. doi request reprint Evaluation of the current management protocols for prophylaxis against Pneumocystis jiroveci pneumonia and other opportunistic infections in patients living with HIV/AIDS
    Sheel Bhadra Jain
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    AIDS Care 23:846-50. 2011
    ..Prophylaxis in AIDS patients seems to be a major problem area and a lot of efforts need to be directed toward it since patients suffering from AIDS are bound to have a downhill course despite provision of all available treatment options...
  79. doi request reprint Epidemiology of nosocomial infections in medicine intensive care unit at a tertiary care hospital in northern India
    Shabina Habibi
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
    Trop Doct 38:233-5. 2008
    ..3% of Escherichia coli were resistant to the third generation cephalosporins. An increased duration of the time spent in intensive care units and days of intervention were associated with incident NI...
  80. pmc Association of Intracellular T(H)1-T(H)2 Balance in CD4+ T-cells and MIP-1α in CD8+ T-cells with Disease Severity in Adults with Dengue
    Tamilarasu Kadhiravan
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Immune Netw 10:164-72. 2010
    ..We tested the hypothesis that dengue haemorrhagic fever (DHF) is associated with a T(H)1-skewed immune response as opposed to dengue fever (DF)...
  81. ncbi request reprint Role of acute viral hepatitis as a confounding factor in antituberculosis treatment induced hepatotoxicity
    Pawan Sarda
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 129:64-7. 2009
    ..Acute viral hepatitis (AVH) is an important confounding reason which clinically, biochemically and histologically mimics DIH...
  82. ncbi request reprint Body-mass index, waist-size, waist-hip ratio and cardiovascular risk factors in urban subejcts
    R Gupta
    Department of Medicine, Monilek Hospital and Research Centre, Jawahar Nagar, Jaipur 302004, India
    J Assoc Physicians India 55:621-7. 2007
    ..To determine association of obesity, measured by body-mass index (BMI), waist-size or waist-hip ratio (WHR), with multiple risk factors in an urban Indian population we performed an epidemiological study...
  83. ncbi request reprint Distribution of CCR2 polymorphism in HIV-1-infected and healthy subjects in North India
    G Kaur
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Int J Immunogenet 34:153-6. 2007
    ....
  84. ncbi request reprint Scientific basis of directly observed treatment, short-course (DOTS)
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029
    J Indian Med Assoc 101:157-8, 166. 2003
    ..Patients with HIV infection and TB disease respond well to antituberculosis treatment if they are given short-course chemotherapy in the programme of DOTS...
  85. ncbi request reprint Clinical and genetic risk factors for the development of multi-drug resistant tuberculosis in non-HIV infected patients at a tertiary care center in India: a case-control study
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
    Infect Genet Evol 3:183-8. 2003
    ..2; 95% CI [2.1-31.3]) as independent predictors of MDR-TB. Our results suggest that a combination of clinical and immunogenetic parameters could provide better information on drug resistance in tuberculosis with implications in therapy...
  86. ncbi request reprint Polymorphism in the CCR5 gene promoter and HIV-1 infection in North Indians
    Gurvinder Kaur
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India
    Hum Immunol 68:454-61. 2007
    ..Further studies are required to confirm these findings and understand the effect of CCR5 polymorphisms on the outcome of HIV-1 infection...
  87. ncbi request reprint Significance of haematological manifestations in patients with tuberculosis
    K J Singh
    Department of Medicine, All India Institute of Medical Sciences, New Delhi
    J Assoc Physicians India 49:788, 790-4. 2001
    ....
  88. pmc HIV & immune reconstitution inflammatory syndrome (IRIS)
    Surendra K Sharma
    Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 134:866-77. 2011
    ....
  89. ncbi request reprint Evaluation of clinical and immunogenetic risk factors for the development of hepatotoxicity during antituberculosis treatment
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Am J Respir Crit Care Med 166:916-9. 2002
    ..0), and presence of HLA-DQB1*0201 (OR 1.9) were independent risk factors for DIH. Our results suggest that the risk of hepatotoxicity from antituberculosis drugs is influenced by clinical and genetic factors...
  90. ncbi request reprint Immunogenetics of mycobacterial infections in the North Indian population
    M Singh
    Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi 110029, India
    Tissue Antigens 69:228-30. 2007
    ....
  91. pmc Evaluation of efficacy and safety of fixed dose lovastatin and niacin(ER) combination in asian Indian dyslipidemic patients: a multicentric study
    Manoj Sharma
    Clinical Research Division, Panacea Biotec Ltd, New Delhi, India
    Vasc Health Risk Manag 2:87-93. 2006
    ..Satisfactory safety and tolerability profile in this population was also demonstrated...
  92. ncbi request reprint Ophthalmic manifestations of HIV infections in India in the era of HAART: analysis of 100 consecutive patients evaluated at a tertiary eye care center in India
    Sujit Gharai
    Dr Rajendra Prasad Center for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
    Ophthalmic Epidemiol 15:264-71. 2008
    ..To evaluate ophthalmic manifestations in patients with Human Immunodeficiency Virus (HIV) infection in the era of highly active antiretroviral therapy (HAART) at the apex institute for eye healthcare in India...
  93. ncbi request reprint High resolution CT (HRCT) in miliary tuberculosis (MTB) of the lung: Correlation with pulmonary function tests & gas exchange parameters in north Indian patients
    S N J Pipavath
    Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India
    Indian J Med Res 126:193-8. 2007
    ..We made an attempt in this study to identify patterns of pulmonary MTB on HRCT and to correlate the HRCT disease extent with pulmonary function tests (PFT) and gas exchange analysis (GEA)...
  94. ncbi request reprint Angiotensin converting enzyme genotype affects development and course of sarcoidosis in Asian Indians
    Mohammad Tahir
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    Sarcoidosis Vasc Diffuse Lung Dis 24:106-12. 2007
    ..Present study was designed to evaluate the relationship between I/D polymorphism and susceptibility to develop sarcoidosis and its effect on SACE activity and disease course in Asian Indian patients with sarcoidosis...
  95. pmc Diffuse small bowel thickening in AIDS patient--a case report
    Rohit Singla
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    BMC Infect Dis 10:310. 2010
    ..Diarrhea is common in HIV/AIDS patients, caused by both classic enteric pathogens and different opportunistic agents. Infection with these different pathogens may lead to similar radiological findings, thus causing diagnostic confusion...
  96. ncbi request reprint The use of diagnostic bronchoscopy in lung cancer
    S K Sharma
    All India Institute of Medical Sciences, New Delhi
    Natl Med J India 5:162-6. 1992
    ..Patients with non-resolving pneumonia, pleural effusion, metastatic disease and non-specific lesions on chest X-ray should receive a low priority for bronchoscopy...
  97. ncbi request reprint Clinical characteristics, pulmonary function abnormalities and outcome of prednisolone treatment in 106 patients with sarcoidosis
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi
    J Assoc Physicians India 49:697-704. 2001
    ..A high index of clinical suspicion and histopathological confirmation early in the illness are required to ascertain the diagnosis lest these patients will get treated as tuberculosis with potentially hepatotoxic drugs...
  98. ncbi request reprint Non resolving pneumonia in a young boy
    Randeep Guleria
    Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi
    Indian J Chest Dis Allied Sci 44:183-5. 2002
  99. ncbi request reprint Uncommon manifestations of sarcoidosis
    S K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
    J Assoc Physicians India 52:210-4. 2004
    ..To study the uncommon manifestations in patients of sarcoidosis...
  100. ncbi request reprint Fibreoptic bronchoscopy in the diagnosis of sputum smear-negative pulmonary tuberculosis: current status
    Alladi Mohan
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
    Indian J Chest Dis Allied Sci 50:67-78. 2008
    ..Proper precautions must be followed to disinfect the bronchoscope in between use so as to minimise the risk of nosocomial transmission of infection...
  101. ncbi request reprint Structural and functional abnormalities in lungs in patients with achalasia
    G K Makharia
    Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India
    Neurogastroenterol Motil 21:603-8, e20. 2009
    ..3%) each]. There was a significant association between presence of regurgitation and dilatation of oesophagus (P = 0.032). More than half (53.3%) of patients with achalasia have structural and/or functional abnormalities in lungs...