Research Topics
Genomes and Genes | Anoop MisraSummaryAffiliation: All India Institute of Medical Sciences Country: India Publications
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Publications
Factors, definitions, predictive value & Asian Indian ethnicity: complexities of the metabolic syndromeAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Hospitals, New Delhi, India
Indian J Med Res 127:293-6. 2008
Waist circumference criteria for the diagnosis of abdominal obesity are not applicable uniformly to all populations and ethnic groupsAnoop Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Nutrition 21:969-76. 2005....
Heterogeneous phenotypes of insulin resistance and its implications for defining metabolic syndrome in Asian Indian adolescentsNaval K Vikram
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
Atherosclerosis 186:193-9. 2006..We propose that BMI and fasting insulin should be evaluated in candidate definitions of metabolic syndrome in Asian Indian adolescents...
Obesity, the metabolic syndrome, and type 2 diabetes in developing countries: role of dietary fats and oilsAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Hospital, Vasant Kunj, New Delhi, India
J Am Coll Nutr 29:289S-301S. 2010..Such actions would contribute to decelerating further escalation of "epidemics" of obesity, the metabolic syndrome, and T2DM in developing countries...
Childhood obesity in developing countries: epidemiology, determinants, and preventionNidhi Gupta
Department of Pediatrics, Children s Hospital of Michigan, Detroit, Michigan 48201, USA
Endocr Rev 33:48-70. 2012..Also, high-risk screening and effective health educational programs are urgently needed in developing countries...
Consensus physical activity guidelines for Asian IndiansAnoop Misra
Fortis CDOC Center of Excellence for Diabetes, Metabolic Diseases and Endocrinology, Fortis Flt Lt Rajan Dhall Hospital, New Delhi, India
Diabetes Technol Ther 14:83-98. 2012..Proper application of guidelines is likely to have a significant impact on the prevalence and management of obesity, the metabolic syndrome, T2DM, and CHD in Asian Indians...
Clinical outcomes in typhoid fever: adverse impact of infection with nalidixic acid-resistant Salmonella typhiTamilarasu Kadhiravan
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
BMC Infect Dis 5:37. 2005..These strains are identifiable by their nalidixic acid-resistance. We studied the impact of infection with nalidixic acid-resistant S. typhi (NARST) on clinical outcomes in patients with bacteriologically-confirmed typhoid fever...
The role of lipids in the development of diabetic microvascular complications: implications for therapyAnoop Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Am J Cardiovasc Drugs 3:325-38. 2003....
Receiver operating characteristics curve analysis of body fat & body mass index in dyslipidaemic Asian IndiansA Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Indian J Med Res 117:170-9. 2003..Optimal limit of body mass index (BMI) for Asian Indians remains to be defined. In this study, we describe the anthropometric and lipid profiles and determine the appropriate cut-offs of BMI for defining obesity in dyslipidaemic patients...
Metabolic syndrome in children: current issues and South Asian perspectiveAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Hospital, Vasant Kunj, New Delhi, India
Nutrition 23:895-910. 2007..The objective of this review is to discuss definition, determinants, and management issues of the metabolic syndrome in children with a focus on South Asians...
Childhood obesity in Asian Indians: a burgeoning cause of insulin resistance, diabetes and sub-clinical inflammationSwati Bhardwaj
Department of Diabetes and Metabolic Diseases Fortis Flt Lt Rajan Dhall Hospital, New Dheli, India
Asia Pac J Clin Nutr 17:172-5. 2008..Both high-risk surveillance and cost-effective population intervention programs are urgently needed. In this context, we have launched one of the largest program ("MARG", The Path) to curb childhood obesity in India...
South Asian diets and insulin resistanceAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Hospital, Vasant Kunj, New Delhi 110070, India
Br J Nutr 101:465-73. 2009....
Obesity and the metabolic syndrome in developing countriesAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Flt Lt Rajan Dhall Hospital, Vasant Kunj, New Delhi 110070, India
J Clin Endocrinol Metab 93:S9-30. 2008..Prevalence of obesity and the metabolic syndrome is rapidly increasing in developing countries, leading to increased morbidity and mortality due to type 2 diabetes mellitus (T2DM) and cardiovascular disease...
Novel phenotypic markers and screening score for the metabolic syndrome in adult Asian IndiansAnoop Misra
The Department of Diabetes and Metabolic Diseases, Fortis Hospitals, New Delhi, India
Diabetes Res Clin Pract 79:e1-5. 2008..The metabolic syndrome (MS) and type 2 diabetes mellitus (T2DM) are common in Asian Indians. Simple yet reliable phenotypic markers are needed for early detection of the MS in Asian Indians...
Migration and its impact on adiposity and type 2 diabetesAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Hospital, New Delhi, India
Nutrition 23:696-708. 2007..The important contributory factors to this phenomenon were urbanization, mechanization, and changes in nutrition and lifestyle behaviors, but the role of stress and as yet unknown factors remain to be determined...
C-reactive protein in young individuals: problems and implications for Asian IndiansAnoop Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Nutrition 20:478-81. 2004..Finally, prevention of childhood adiposity is critical to decrease future risk for development of T2DM and CHD, particularly in highly predisposed ethnic groups such as Asian Indians and South Asians...
The metabolic syndrome in South Asians: continuing escalation & possible solutionsAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Flt Lt Rajan Dhall Hospital, New Delhi, India
Indian J Med Res 125:345-54. 2007..Finally, there is an urgent need to conduct research studies regarding the correct definitions of the metabolic syndrome and genetic and perinatal factors related to insulin resistance in South Asians...
Simple anthropometric measures identify fasting hyperinsulinemia and clustering of cardiovascular risk factors in Asian Indian adolescentsAnoop Misra
Department of Diabetes and Metabolic Disorders, Fortis Hospital, New Delhi 110016, India
Metabolism 55:1569-73. 2006..These simple measurements are useful for preventing and predicting cardiovascular risk and for generating a correct definition of the metabolic syndrome...
High prevalence of insulin resistance in postpubertal Asian Indian children is associated with adverse truncal body fat patterning, abdominal adiposity and excess body fatA Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
Int J Obes Relat Metab Disord 28:1217-26. 2004..The objectives were to study the relationships of insulin resistance with generalized and abdominal obesity, and body fat patterning in urban postpubertal Asian Indian children...
An evaluation of candidate definitions of the metabolic syndrome in adult Asian IndiansAnoop Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
Diabetes Care 28:398-403. 2005....
Carbohydrate diets, postprandial hyperlipidaemia, abdominal obesity and Asian Indians: a recipe for atherogenic disasterAnoop Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029
Indian J Med Res 121:5-8. 2005
Effect of supervised progressive resistance-exercise training protocol on insulin sensitivity, glycemia, lipids, and body composition in Asian Indians with type 2 diabetesAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Flt Lt Rajan Dhall Hospital, New Delhi, India
Diabetes Care 31:1282-7. 2008..To evaluate the effect of supervised progressive resistance-exercise training (PRT) protocol on insulin sensitivity, glycemia (blood glucose and A1C levels), lipids, and body composition in Asian Indians with type 2 diabetes...
The metabolic syndrome in South Asians: epidemiology, determinants, and preventionAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Hospital, Vasant Kunj, Delhi, India
Metab Syndr Relat Disord 7:497-514. 2009..The prevalence of obesity and the metabolic syndrome is rapidly increasing in India and other south Asian countries, leading to increased morbidity and mortality due to type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD)...
Nutrition transition in India: secular trends in dietary intake and their relationship to diet-related non-communicable diseasesAnoop Misra
Fortis C DOC Centre of Excellence for Diabetes, Obesity, Metabolic Diseases and Endocrinology, Vasant Kunj, New Delhi 110070, India
J Diabetes 3:278-92. 2011....
Obesity-related non-communicable diseases: South Asians vs White CaucasiansA Misra
National Diabetes, Obesity, and Cholesterol Disorders Foundation N DOC, New Delhi, India
Int J Obes (Lond) 35:167-87. 2011..Finally, lower cut-offs of obesity and abdominal obesity for South Asians are expected to help physicians in better and more effective prevention of OR-NCDs...
The high burden of obesity and abdominal obesity in urban Indian schoolchildren: a multicentric study of 38,296 childrenAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Hospital, New Delhi, India
Ann Nutr Metab 58:203-11. 2011..The objective of this study was to assess the prevalence of overweight, obesity and abdominal obesity and their associated factors in a large sample of urban Indian schoolchildren...
Waist circumference cutoff points and action levels for Asian Indians for identification of abdominal obesityA Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi
Int J Obes (Lond) 30:106-11. 2006..To test the validity of internationally accepted waist circumference (WC) action levels for adult Asian Indians...
Consensus dietary guidelines for healthy living and prevention of obesity, the metabolic syndrome, diabetes, and related disorders in Asian IndiansAnoop Misra
Fortis CDOC Center of Excellence for Diabetes, Obesity Metabolic Diseases and Endocrinology, Fortis Flt Lt Rajan Dhall Hospital, Vasant Kunj, New Delhi 110070, India
Diabetes Technol Ther 13:683-94. 2011..Proper application of these guidelines will help curb the rising "epidemics" of obesity, the metabolic syndrome, hypertension, T2DM, and CVD in Asian Indians...
Cutoffs of abdominal adipose tissue compartments as measured by magnetic resonance imaging for detection of cardiovascular risk factors in apparently healthy adult Asian Indians in North IndiaAnoop Misra
Department of Diabetes and Metabolic Diseases, Fortis Hospital, Vasant Kunj, New Delhi, India
Metab Syndr Relat Disord 8:243-7. 2010..We aimed to define cutoffs of abdominal adipose tissue depots [total abdominal adipose tissue (TAAT), intraabdominal adipose tissue (IAAT), and abdominal subcutaneous adipose tissue (SCAT)] in adult Asian Indians in North India...
Are biosimilars really generics?Anoop Misra
Fortis Flt Lt Rajan Dhall Hospital, Department of Diabetes and Metabolic Diseases, Vasant Kunj, New Delhi 110070, India
Expert Opin Biol Ther 10:489-94. 2010....
Younger age of escalation of cardiovascular risk factors in Asian Indian subjectsRajeev Gupta
Department of Medicine, Fortis Escorts Hospital, Jaipur 302017, India
BMC Cardiovasc Disord 9:28. 2009..We conducted epidemiological studies to determine prevalence and age-specific trends in cardiovascular risk factors among adolescent and young urban Asian Indians...
Proton magnetic resonance spectroscopy and biochemical investigation of type 2 diabetes mellitus in Asian Indians: observation of high muscle lipids and C-reactive protein levelsSanjeev Sinha
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
Magn Reson Imaging 27:94-100. 2009..These findings have strong implications of increased cardiovascular risk in Asian Indians with T2DM. The absence of relationship between CRP and IMCL needs to be explored further in a study using a large sample size...
Subclinical inflammation and soleus muscle intramyocellular lipids in healthy Asian Indian malesSanjeev Sinha
Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India
Clin Endocrinol (Oxf) 63:350-5. 2005..Studies are needed in other ethnic groups to corroborate these data...
Correlations of C-reactive protein levels with anthropometric profile, percentage of body fat and lipids in healthy adolescents and young adults in urban North IndiaNaval K Vikram
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
Atherosclerosis 168:305-13. 2003....
Imbalanced dietary profile, anthropometry, and lipids in urban Asian Indian adolescents and young adultsNidhi Gupta
Director and Head, Department of Diabetes and Metabolic Diseases, Fortis Flt Lt Rajan Dhall Hospital, Vasant Kunj, New Delhi 110070, India
J Am Coll Nutr 29:81-91. 2010..To analyze the macronutrient, micronutrient, food intake pattern, anthropometry, and lipid profile of urban Asian Indian adolescents and young adults and compare it with the nutrient profile of rural Asian Indian and American adolescents...
Dietary nutrients and insulin resistance in urban Asian Indian adolescents and young adultsSumit Isharwal
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Ann Nutr Metab 52:145-51. 2008..Asian Indians have a high prevalence of insulin resistance that may underlie their higher tendency to develop type 2 diabetes mellitus and early-onset atherosclerosis...
Centiles of anthropometric measures of adiposity for 14- to 18-year-old urban Asian Indian adolescentsRavindra M Pandey
Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India
Metab Syndr Relat Disord 7:133-41. 2009....
Migrating husbands and changing cardiovascular risk factors in the wife: a cross sectional study in Asian Indian womenRajeev Gupta
Department of Medicine, Fortis Escorts Hospital, Jaipur, India
J Epidemiol Community Health 66:881-9. 2012..The authors studied the influence of migration of husband on cardiovascular risk factors in Asian Indian women...
Centile values for serum lipids and blood pressure for Asian Indian adolescentsMalini Madhavan
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
Lipids Health Dis 4:20. 2005..Smoothed age- and sex- specific 5th, 10th, 25th, 50th, 75th, 85th, 90th and 95th percentiles where derived using LMS regression...
Non-obese (body mass index < 25 kg/m2) Asian Indians with normal waist circumference have high cardiovascular riskNaval K Vikram
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Nutrition 19:503-9. 2003..quot; These data suggested that definitions of "normal" ranges of BMI and WC need to be revised for Asian Indians...
Factor analysis of the metabolic syndrome components in urban Asian Indian adolescentsNaval K Vikram
Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India
Asia Pac J Clin Nutr 18:293-300. 2009..Obesity (generalized, abdominal and truncal sub-cutaneous) accounts for the maximum variance in clustering and appears to be the stronger correlate of high cumulative risk rather than hyperinsulinemia...
Trends in prevalence of coronary risk factors in an urban Indian population: Jaipur Heart Watch-4Rajeev Gupta
Department of Medicine, Monilek Hospital and Research Centre, and Department of Home Science, University of Rajasthan, Jaipur, India
Indian Heart J 59:346-53. 2007..To determine prevalence of multiple coronary risk factors in a North Indian Punjabi community and to compare these with previous population based studies in the same city in North India we performed an epidemiological study...
TNF-alpha gene polymorphism and TNF-alpha levels in obese Asian Indians with obstructive sleep apneaBharat Bhushan
Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
Respir Med 103:386-92. 2009..Recent data indicate that inflammation may be an important correlate of OSA. The relationships of OSA with TNFalpha levels and TNFalpha gene promoter polymorphism (-308G/A) have not been investigated in obese Asian Indians with OSA...
Ala/Ala genotype of Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-γ2 gene is associated with obesity and insulin resistance in Asian IndiansSurya Prakash Bhatt
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Diabetes Technol Ther 14:828-34. 2012..We determined the association of the Pro12Ala polymorphism of the peroxisome proliferator activated receptor (PPAR)-γ2 gene with obesity, insulin resistance (IR), and lipids in Asian Indians without diabetes in north India...
Secular trends in obesity, regional adiposity and metabolic parameters among Asian Indian adolescents in north India: a comparative data analysis of two selective samples 5 years apart (2003, 2008)Neha Singhal
Centre for Diabetes, Obesity and Cholesterol Disorders, Diabetes Foundation India, New Delhi, India
Ann Nutr Metab 56:176-81. 2010..To assess and compare the secular trends in anthropometric and biochemical parameters over 5 years (2003-2008) amongst Asian Indian adolescents in north India...
Adiponectin, insulin resistance, and C-reactive protein in postpubertal Asian Indian adolescentsNaval K Vikram
Department of Medicine, All India Institute of Medical Sciences, New Delhi
Metabolism 53:1336-41. 2004..We conclude that generalized obesity affects the adiponectin-insulin relationship in postpubertal Asian Indian males; however, the relationship of adiponectin with hs-CRP needs further evaluation...
Association of peroxisome proliferator activated receptor-γ gene with non-alcoholic fatty liver disease in Asian Indians residing in north IndiaSurya Prakash Bhatt
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India
Gene 512:143-7. 2013..We investigated the association of polymorphisms C161T and Pro12Ala of peroxisome proliferator-activated receptor gamma (PPARγ) with clinical and biochemical parameters in Asian Indians with NAFLD...
Association between subclinical inflammation & fasting insulin in urban young adult north Indian malesN K Vikram
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Indian J Med Res 124:677-82. 2006..Further studies on a larger sample of both genders need to be done to confirm these findings...
Association of the Myostatin gene with obesity, abdominal obesity and low lean body mass and in non-diabetic Asian Indians in north IndiaSurya Prakash Bhatt
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
PLoS ONE 7:e40977. 2012..To determine the association of the A55T and K153R polymorphisms of the Myostatin gene with obesity, abdominal obesity and lean body mass (LBM) in Asian Indians in north India...
SREBP-2 1784 G/C genotype is associated with non-alcoholic fatty liver disease in north IndiansSurya Prakash Bhatt
Department of Biochemistry, New Delhi, India
Dis Markers 31:371-7. 2011..Genetics of non-alcoholic fatty liver (NAFLD) in Asian Indians has been inadequately investigated. This study aims to determine the association of the 1784G>C polymorphism in the SREBP-2 gene with NAFLD in Asian Indians in north India...
Impact of intensive school-based nutrition education and lifestyle interventions on insulin resistance, β-cell function, disposition index, and subclinical inflammation among Asian Indian adolescents: a controlled intervention studyNeha Singhal
National Diabetes, Obesity and Cholesterol Foundation, SDA, New Delhi, India
Metab Syndr Relat Disord 9:143-50. 2011....
Improvement in nutrition-related knowledge and behaviour of urban Asian Indian school children: findings from the 'Medical education for children/Adolescents for Realistic prevention of obesity and diabetes and for healthy aGeing' ( MARG) intervention stuPriyali Shah
National Foundation for Diabetes, Obesity, and Cholesterol Disorders N DOC, New Delhi, India
Br J Nutr 104:427-36. 2010..This successful and comprehensive educative intervention could be incorporated in future school-based health and nutritional education programmes...
Secular trends in prevalence of overweight and obesity from 2006 to 2009 in urban asian Indian adolescents aged 14-17 yearsDeepak Kumar Gupta
National Diabetes, Obesity and Cholesterol Diseases Foundation N DOC, SDA, New Delhi, India
PLoS ONE 6:e17221. 2011..More specifically, the study showed the association of this increasing trend of overweight and obesity prevalence with male gender and high socio-economic status, calling for an urgent need for immediate and targeted preventive measures...
High prevalence of abdominal, intra-abdominal and subcutaneous adiposity and clustering of risk factors among urban Asian Indians in North IndiaSwati Bhardwaj
National Diabetes, Obesity and Cholesterol Diseases Foundation N DOC, SDA, New Delhi, India
PLoS ONE 6:e24362. 2011..To assess the prevalence of abdominal obesity including intra-abdominal and subcutaneous adiposity along with other cardiometabolic risk factors in urban Asian Indians living in New Delhi...
Impact of obesity on the left ventricular functions and morphology of healthy Asian IndiansDavinder S Chadha
Department of Cardiology, Air Force Central Medical Establishment, New Delhi, India
Metab Syndr Relat Disord 7:151-8. 2009..A total of 239 consecutive Asian Indians (175 males and 64 females, ages 17-64 years) were divided into obese and nonobese groups based on body mass index (BMI), waist-to-hip circumference ratio (W-HR), and percentage of body fat (%BF)...
Correlation of regional cardiovascular disease mortality in India with lifestyle and nutritional factorsRajeev Gupta
Department of Medicine, Monilek Hospital and Research Centre, Jawahar Nagar, Jaipur 302004, India
Int J Cardiol 108:291-300. 2006..To determine significance of various nutritional factors and other lifestyle variables in explaining this difference in cardiovascular disease mortality we performed an analysis...
Investigation of hepatic gluconeogenesis pathway in non-diabetic Asian Indians with non-alcoholic fatty liver disease using in vivo ((31)P) phosphorus magnetic resonance spectroscopyRajeev Sharma
Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India
Atherosclerosis 203:291-7. 2009....
Consensus statement for diagnosis of obesity, abdominal obesity and the metabolic syndrome for Asian Indians and recommendations for physical activity, medical and surgical managementA Misra
Department of Diabetes and Metabolic Diseases, Fortis Flt Lt Rajan Dhall Hospital, Vasant Kunj, New Delhi
J Assoc Physicians India 57:163-70. 2009..Till that time, these should be used by clinicians, researchers and policymakers dealing with obesity and related diseases...
Soluble inter-cellular adhesion molecule-1 in urban Asian north Indians: relationships with anthropometric and metabolic covariatesAstha Sethi
Department of Medicine, All India Institute of Medical Sciences, New Delhi
Dis Markers 18:111-20. 2002....
Associations of -308G/A polymorphism of tumor necrosis factor (TNF)-α gene and serum TNF-α levels with measures of obesity, intra-abdominal and subcutaneous abdominal fat, subclinical inflammation and insulin resistance in Asian Indians in north IndiaNaval K Vikram
Departments of Medicine, All India Institute of Medical Sciences, New Delhi
Dis Markers 31:39-46. 2011..We evaluated the relationship of -308G/A polymorphism of TNF-α gene with obesity and insulin resistance in Asian Indians in north India...
Autofluorescence characterization of advanced glycation end products of hemoglobinNadanathangam Vigneshwaran
Centre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi 110016, India
Spectrochim Acta A Mol Biomol Spectrosc 61:163-70. 2005..55). The results suggest a non-linear relation between glycemia and glycation, indicating the application of Hb-AGE as a measure of susceptibility to glycation rather than glycation itself...
Genotype of the LMNA 1908C>T variant is associated with generalized obesity in Asian Indians in North IndiaMukti Sharma
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India
Clin Endocrinol (Oxf) 75:642-9. 2011..To determine the frequency distribution of LMNA 1908C>T SNP and its association with generalized obesity, abdominal obesity and coexistent metabolic disorders in nondiabetic Asian Indians living in a metropolitan city of north India...
Diet & insulin resistance: a review & Asian Indian perspectiveSumit Isharwal
Department of Medicine SI, All India Institute of Medical Sciences, New Delhi, India
Indian J Med Res 129:485-99. 2009..Such imbalanced diets contribute to high prevalence of insulin resistance, the metabolic syndrome and T2DM in South Asians and Asian Indians...
Predictive equations for body fat and abdominal fat with DXA and MRI as reference in Asian IndiansKashish Goel
Department of Medicine, Maulana Azad Medical College, New Delhi, India
Obesity (Silver Spring) 16:451-6. 2008....
Comparison of short insulin tolerance test with HOMA Method for assessment of insulin sensitivity in Asian Indians in north IndiaRajeev Sharma
Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi 110029, India
Diabetes Res Clin Pract 82:e9-12. 2008..Cost-effective method to assess insulin resistance is needed for Asian Indians...
Obstructive sleep apnoea correlates with C-reactive protein in obese Asian IndiansBharat Bhushan
Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
Nutr Metab Cardiovasc Dis 19:184-9. 2009..Whether the relationship of obstructive sleep apnoea (OSA) and CRP is independent of adiposity, needs to be investigated...
Non-obese hyperlipidemic Asian northern Indian males have adverse anthropometric profileA Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Nutr Metab Cardiovasc Dis 12:178-83. 2002..Hyperlipidemia is commonly ascribed to obesity. We studied the association of anthropometric profile and nutrient intake with hyperlipidemia in non-obese Asian Indian males...
Anthropometry and body composition in northern Asian Indian patients with type 2 diabetes: receiver operating characteristics (ROC) curve analysis of body mass index with percentage body fat as standardN K Vikram
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Diabetes Nutr Metab 16:32-40. 2003..Revised definition of obesity using lower cut off of BMI, or based on %BF in northern Asian Indian T2DM patients will lead to a more rational application of dietary restriction, lifestyle measures, and use of metformin...
Clinical and pathophysiological consequences of abdominal adiposity and abdominal adipose tissue depotsAnoop Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Nutrition 19:457-66. 2003..To highlight the clinical and metabolic correlates of abdominal obesity and various abdominal adipose tissue depots...
Hyperhomocysteinemia, and low intakes of folic acid and vitamin B12 in urban North IndiaAnoop Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi
Eur J Nutr 41:68-77. 2002..To test this hypothesis, we studied serum levels of Hcy in subjects living in an urban slum of North India and healthy subjects from urban nonslum area...
Apolipoprotein E gene polymorphisms in patients with premature myocardial infarction: a case-controlled study in Asian Indians in North IndiaPrabhat Kumar
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
Ann Clin Biochem 40:382-7. 2003..This study aimed to study the role of apo E gene polymorphisms in premature MI patients and their relation to serum lipid levels...
Distribution and cutoff points of fasting insulin in Asian Indian adolescents and their association with metabolic syndromeN K Vikram
Department of Medicine, Fortis Hospitals, New Delhi, 110070, India
J Assoc Physicians India 56:949-54. 2008..To evaluate the levels and appropriate cutoff points of fasting insulin, and their association with the metabolic syndrome (MS) in Asian Indian adolescents...
Apolipoprotein E polymorphism in Northern Indian patients with coronary heart disease: phenotype distribution and relation to serum lipids and lipoproteinsKalpana Luthra
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi
Mol Cell Biochem 232:97-102. 2002..Further, apo E phenotype is positively correlated with high Lp(a) levels in the CHD subjects having at least one E4 allele. However, these relationships need to be explored in a larger sample of subjects...
Insulin resistance syndrome (metabolic syndrome) and obesity in Asian Indians: evidence and implicationsAnoop Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Nutrition 20:482-91. 2004..This review describes prevalence, determinants, and possible pathophysiologic mechanisms and suggests management and research directions for insulin resistance syndrome (metabolic syndrome) in Asian Indians...
High prevalence of diabetes, obesity and dyslipidaemia in urban slum population in northern IndiaA Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Int J Obes Relat Metab Disord 25:1722-9. 2001....
Adverse profile of dietary nutrients, anthropometry and lipids in urban slum dwellers of northern IndiaA Misra
Department of Medicine, All India Institute of Medicine, New Delhi, India
Eur J Clin Nutr 55:727-34. 2001..The aim of this study was to assess nutrient profile and its association with the anthropometry, percentage body fat (%BF) and blood lipids in the urban slum dwellers in northern India...
Relation between plasma leptin and anthropometric and metabolic covariates in lean and obese diabetic and hyperlipidaemic Asian Northern Indian subjectsA Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi
Diabetes Nutr Metab 14:18-26. 2001..Among other components of metabolic syndrome, only abdominal obesity is weakly correlated to serum leptin levels...
Proton magnetic resonance spectroscopy study of soleus muscle in non-obese healthy and Type 2 diabetic Asian Northern Indian males: high intramyocellular lipid content correlates with excess body fat and abdominal obesityA Misra
Departments of Medicine, Nuclear Magnetic Resonance and Biostatistics, All India Institute of Medical Sciences, New Delhi, India
Diabet Med 20:361-7. 2003....
BMI does not accurately predict overweight in Asian Indians in northern IndiaV Dudeja
Department of Medicine, All India Institute of Medical Sciences, New Delhi-110029, India
Br J Nutr 86:105-12. 2001....
Comparison of definitions of the metabolic syndrome in adult Asian IndiansJ S Wasir
Department of Diabetes and Metabolic Diseases, Fortis Hospitals, New Delhi, 110070, India
J Assoc Physicians India 56:158-64. 2008....
Correlates of Type 2 diabetes mellitus in children, adolescents and young adults in north India: a multisite collaborative case-control studyN K Vikram
Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi, India
Diabet Med 23:293-8. 2006..1 (10.8-1164.7). CONCLUSIONS: Early identification of the simple clinical, anthropometric and biochemical parameters which are strongly associated with early onset T2DM in young Asian Indians may be useful for primary prevention...
A case-control study on insulin resistance, metabolic co-variates & prediction score in non-alcoholic fatty liver diseaseS Bajaj
Department of Medicine, Motilal Nehru Medical College, Allahabad, India
Indian J Med Res 129:285-92. 2009..We studied anthropometric parameters, insulin resistance and metabolic co-variates in subjects with NAFLD as compared to those without NAFLD, and also developed a prediction score for NAFLD...
Simvastatin retards progression of retinopathy in diabetic patients with hypercholesterolemiaKaushik Sen
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
Diabetes Res Clin Pract 56:1-11. 2002..The potential of this class of drugs for the primary prevention of DR and other microvascular complications needs to be explored further...
Plasma plasminogen activator inhibitor-1 activity in normoglycemic hypertriglyceridemic north Asian Indian subjects: a preliminary case-control studyR Sarkar
Department of Medicine, All India Institute of Medical Sciences, New Delhi
Indian Heart J 53:61-5. 2001..Procoagulant tendency is further enhanced if hypertriglyceridemia and hyperinsulinemia are added on to obesity...
Hyperinsulinemia and dyslipidemia in non-obese, normotensive offspring of hypertensive parents in northern IndiaA Misra
Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi
Blood Press 7:286-90. 1998..These metabolic abnormalities may be associated with hypertension, glucose intolerance and accelerated atherosclerosis in adulthood...
Evaluation of autofluorescent property of hemoglobin-advanced glycation end product as a long-term glycemic index of diabetesBijukumar Gopalkrishnapillai
Biomedical Engineering Unit, All India Institute of Medical Sciences, New Delhi, India
Diabetes 52:1041-6. 2003..Based on the results obtained, Hb-AGE appears to be an efficient fluorescence-based biosensing molecule for the long-term monitoring of glycemic control in diabetes...
Dyslipidemia in Asian Indians: determinants and significanceA Misra
Dept. of Medicine, All India Institute of Medical Sciences, New Delhi-110 029, India
J Assoc Physicians India 52:137-42. 2004..However, optimal management requires consideration of ethnic-specific dietary, lifestyle and management factors to formulate individual treatment guidelines...
Pulmonary functions in patients with type 2 diabetes mellitus & correlation with anthropometry & microvascular complicationsSanjeev Sinha
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
Indian J Med Res 119:66-71. 2004..Pathophysiologically, it could be related to glycaemic control or dyslipidaemia. Correlation of % BF with DLCo needs to be explored further...
Revisions of cutoffs of body mass index to define overweight and obesity are needed for the Asian-ethnic groupsA Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India
Int J Obes Relat Metab Disord 27:1294-6. 2003
Relationship of Xba1 and EcoR1 polymorphisms of apolipoprotein-B gene to dyslipidemia and obesity in Asian Indians in North IndiaA Misra
Department of Medicine and Biostatistics, All India Institute of Medical Sciences, New Delhi
Indian Heart J 53:177-83. 2001..Genetic investigation of dyslipidemia and obesity prevalent in the Indian population form the basis of this study...
Risk factors for atherosclerosis in young individualsA Misra
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
J Cardiovasc Risk 7:215-29. 2000..These measures, starting from childhood, should be applied to all and in particular to the susceptible offspring, predisposed individuals, and populations...
Effects of controlled school-based multi-component model of nutrition and lifestyle interventions on behavior modification, anthropometry and metabolic risk profile of urban Asian Indian adolescents in North IndiaN Singhal
Centre for Diabetes, Obesity and Cholesterol Disorders C DOC, Diabetes Foundation India, New Delhi, India
Eur J Clin Nutr 64:364-73. 2010..To study the effectiveness of a multi-component intervention model of nutrition and lifestyle education on behavior modification, anthropometry and metabolic risk profile of urban Asian-Indian adolescents in North India...
Role of pleural fluid cholesterol in differentiating transudative from exudative pleural effusionR Guleria
Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
Natl Med J India 16:64-9. 2003..However, the difference in lipid profile between tubercular and non-tubercular pleural effusion has not been studied...
Leptin and its correlation with exocrine and endocrine pancreatic function in idiopathic chronic pancreatitis: implications for pathophysiologyShallu Midha
Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India
Pancreas 35:262-6. 2007..Leptin alters pancreatic exocrine and beta-cell secretion in animal studies. We hypothesized that leptin might be important in the pathogenesis of idiopathic chronic pancreatitis (ICP) and/or the development of diabetes in ICP...
Evaluation of cerebral blood flow by single-photon emission computed tomography in young Asian Indians with hypertensionS Sinha
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
J Hum Hypertens 20:143-8. 2006..These subjects may also be researched as potential candidates for preventive antiplatelet therapy...
Correlation of acetylator phenotype with peripheral, autonomic and central neuropathy in Northern Indian non-insulin-dependent diabetes mellitus patientsA Misra
Centre of Clinical Pharmacology, Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi
Eur J Clin Pharmacol 55:419-24. 1999....
Whole grains and health: perspective for Asian IndiansA Misra
Department of Diabetes and Metabolic Diseases, Fortis Hospital, Vasant Kunj, New Delhi, 110070, India
J Assoc Physicians India 57:155-62. 2009..Grains have shown to have a role in prevention and reducing the risk of type 2 diabetes, coronary heart disease, cancer and obesity...
Insulin treatment in non-insulin dependent diabetes mellitusA Misra
Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi
Natl Med J India 8:169-77. 1995..The presence of such dysregulation is included in the recently described syndrome X.(ABSTRACT TRUNCATED AT 250 WORDS)..
Subcutaneous abdominal adipose tissue is associated with the metabolic syndrome in Asian Indians independent of intra-abdominal and total body fatKashish Goel
Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Heart 96:579-83. 2010..Subcutaneous abdominal adipose tissue (SCAT) compared with intra-abdominal adipose tissue (IAAT) would be more significantly associated with the metabolic syndrome in Asian Indians...
Action and research are needed for evaluation of optimal definitions of anthropometric parameters and metabolic syndrome for AsiansAnoop Misra
Diabetes Res Clin Pract 68:178-9. 2005
Body composition and the metabolic syndrome in Asian Indians: a saga of multiple adversitiesAnoop Misra
Natl Med J India 16:3-7. 2003
