Olafur Andri Stefansson

Summary

Affiliation: University of Iceland
Country: Iceland

Publications

  1. ncbi Genomic and phenotypic analysis of BRCA2 mutated breast cancers reveals co-occurring changes linked to progression
    Olafur A Stefansson
    Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland
    Breast Cancer Res 13:R95. 2011
  2. ncbi Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes
    Olafur Andri Stefansson
    Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland
    Breast Cancer Res 11:R47. 2009
  3. ncbi CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer
    Olafur Andri Stefansson
    Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Epigenetics 6:638-49. 2011
  4. ncbi Tetraploidy in BRCA2 breast tumours
    Asta Björk Jonsdottir
    Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Eur J Cancer 48:305-10. 2012

Collaborators

Detail Information

Publications4

  1. ncbi Genomic and phenotypic analysis of BRCA2 mutated breast cancers reveals co-occurring changes linked to progression
    Olafur A Stefansson
    Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland
    Breast Cancer Res 13:R95. 2011
    ..Here, we explore the impact of DNA copy-number changes in BRCA2 tumors with respect to phenotype and clinical staging of the disease...
  2. ncbi Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes
    Olafur Andri Stefansson
    Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland
    Breast Cancer Res 11:R47. 2009
    ..Somatic mutations in BRCA1 and BRCA2 have not been found and the involvement of these genes in sporadic tumour development therefore remains unclear...
  3. ncbi CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer
    Olafur Andri Stefansson
    Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Epigenetics 6:638-49. 2011
    ..The clinical implications relate to the potential use of targeted treatment based on PARP inhibitors in sporadic TNBCs, wherein CpG island hypermethylation of BRCA1 represents a potential marker of therapeutic response...
  4. ncbi Tetraploidy in BRCA2 breast tumours
    Asta Björk Jonsdottir
    Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Eur J Cancer 48:305-10. 2012
    ..Additionally, tetraploidy emerges predominantly in BRCA2 breast cancers displaying luminal rather than triple-negative phenotypes...