Fridbert Jonasson

..To examine the age- and gender-specific 5-year incidence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik...

..To locate the mildest and/or earliest changes in the retina and/or choroid in Sveinsson chorioretinal atrophy (SCRA), using more advanced techniques than previous studies...

..To describe the prevalence and signs of early and late age-related macular degeneration (AMD) in an old cohort...

..These results have now largely been replicated world-wide...

..To examine the age- and sex-specific prevalence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik, Iceland, who were 50 years and older...

..27 to 0.80; P = .006). CONCLUSIONS: Risk factors for drusen appear to differ from risk factors for pigmentary abnormalities. The effect of smoking on developing AMD is partly masked by selective mortality...

..To examine the 5-year incidence of pseudoexfoliation (PEX) and monitor changes in related ophthalmologic variables...

..To examine the age and sex-specific prevalence of pseudoexfoliation syndrome (PEX) and its relationship with some ophthalmological variables...

..The authors study the population-based incidence of exudative AMD in Iceland and the use of intravitreal ranibizumab in a defined population...

..This study examined age, sex and cause-specific 5-year incidence of visual impairment and blindness in a middle-aged and elderly Icelandic population...

..To examine the age- and gender-specific prevalent and 5-year incident risk of developing exfoliation syndrome (XFS)...

..This study aimed to study the prevalences and causes of visual impairment and blindness in an Icelandic adult population...

..02). CONCLUSIONS: Cornea guttata seem to be found more commonly in women than in men. Smoking for more than 20 pack-years increases the risk of developing CG more than 2-fold...

..There was also an age-related shift against the rule for the axis of astigmatism during the 5-year period. Our results may be useful for predicting long-term outcome of refractive surgery...

..595, p < 0.0001). DISCUSSION: Our results indicate that there is a significant relationship between height and several ocular dimensions in this adult population and confirms a negative correlation between axial length and refraction...

..To study age-related macular degeneration (AMD) in old and very old individuals with family history of AMD to find the proportion of those with early and advanced AMD...

..Radius of CC was found to be age-independent and significantly steeper in females than in males. CCT appears to be independent of age and gender. Greater CCT is associated with higher mean IOP...

..CONCLUSIONS: Ageing is a major risk factor for nuclear lens opacification, and smoking is a major modifiable risk factor. Cortical and nuclear lens opacifications do not share the same modifiable risk factors...

..However, its impact on soft drusen, GA, or neovascular AMD--or the relationship between them--is unclear...

..Aviation involves exposure to ionizing radiation of cosmic origin. The association between lesions of the ocular lens and ionizing radiation is well-known...

..To report the histopathologic features in an eye with Sveinsson chorioretinal atrophy (SCRA), also termed helicoid peripapillary chorioretinal degeneration, for the first time...

..Vascular endothelial growth factor antibodies reduce the risk of blindness and improve vision in patients with age-related macular degeneration...

..42, P = 0.0021). The risk variant identified here is located close to CAV1 and CAV2, both of which are expressed in the trabecular meshwork and retinal ganglion cells that are involved in the pathogenesis of POAG...

..To compare the characteristics of early cortical cataract localization in three groups in cataract epidemiologic surveys performed in Reykjavík, Melbourne, and Singapore...

..206 +/- 0.029 inches). The corrected horizontal measurement showed the same pattern. CONCLUSIONS: In the Reykjavik Eye Study, optic disks meeting structural criteria for glaucoma are significantly larger than normal nerves...

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..Therefore, we conclude that the mutation in the TEAD1 gene is the cause of Sveinsson's chorioretinal atrophy...

..To investigate racial differences of lens transparency properties and the prevalence of lens opacification by age...

..We sought to examine whether microvascular lesions in the retina and in the brain are associated and whether this association differs among people with and without diabetes...

..3 is associated with freckles. The fifth region provided refinements to a previously reported association in OCA2, and the sixth encompasses previously described variants in MC1R...

..The population-attributable risk is more than 99%. The product of LOXL1 catalyzes the formation of elastin fibers found to be a major component of the lesions in XFG...

..To identify CHST6 mutations in five additional Icelandic cases of macular corneal dystrophy (MCD) type I and in four families with MCD type II from Iceland...

..To study the correlation between ocular refraction and the refractive components (corneal power, lens power and axial length) in a population-based sample of normal subjects...