Fridbert Jonasson

Summary

Affiliation: Landspitali University Hospital
Country: Iceland

Publications

  1. pmc Prevalence of age-related macular degeneration in old persons: Age, Gene/environment Susceptibility Reykjavik Study
    Fridbert Jonasson
    Ophthalmology, Landspitali University Hospital, Iceland
    Ophthalmology 118:825-30. 2011
  2. ncbi request reprint 5-year incidence of age-related maculopathy in the Reykjavik Eye Study
    Fridbert Jonasson
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Ophthalmology 112:132-8. 2005
  3. ncbi request reprint Sveinsson chorioretinal atrophy: the mildest changes are located in the photoreceptor outer segment/retinal pigment epithelium junction
    Fridbert Jonasson
    Department of Ophthalmology, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Acta Ophthalmol Scand 85:862-7. 2007
  4. doi request reprint From epidemiology to lysyl oxidase like one (LOXL1) polymorphisms discovery: phenotyping and genotyping exfoliation syndrome and exfoliation glaucoma in Iceland
    Fridbert Jonasson
    University of Iceland, Landspitali, Reykjavik, Iceland
    Acta Ophthalmol 87:478-87. 2009
  5. ncbi request reprint The prevalence of age-related maculopathy in iceland: Reykjavik eye study
    Fridbert Jonasson
    Department of Ophthalmology, University Iceland, Reykjavik, Iceland
    Arch Ophthalmol 121:379-85. 2003
  6. ncbi request reprint Risk factors for five-year incident age-related macular degeneration: the Reykjavik Eye Study
    Arsaell Arnarsson
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Am J Ophthalmol 142:419-28. 2006
  7. doi request reprint Pseudoexfoliation in the reykjavik eye study: five-year incidence and changes in related ophthalmologic variables
    Arsaell Arnarsson
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Am J Ophthalmol 148:291-7. 2009
  8. ncbi request reprint Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables
    Arsaell Arnarsson
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Acta Ophthalmol Scand 85:822-7. 2007
  9. doi request reprint Population-based incidence of exudative age-related macular degeneration and ranibizumab treatment load
    Asbjorg Geirsdottir
    Department of Ophthalmology, Landspitali The National University Hospital of Iceland, Reykjavik, Iceland
    Br J Ophthalmol 96:444-7. 2012
  10. doi request reprint Exfoliation syndrome in the Reykjavik Eye Study: risk factors for baseline prevalence and 5-year incidence
    Arsaell Arnarsson
    Department of Ophthalmology, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Br J Ophthalmol 94:831-5. 2010

Detail Information

Publications36

  1. pmc Prevalence of age-related macular degeneration in old persons: Age, Gene/environment Susceptibility Reykjavik Study
    Fridbert Jonasson
    Ophthalmology, Landspitali University Hospital, Iceland
    Ophthalmology 118:825-30. 2011
    ..To describe the prevalence and signs of early and late age-related macular degeneration (AMD) in an old cohort...
  2. ncbi request reprint 5-year incidence of age-related maculopathy in the Reykjavik Eye Study
    Fridbert Jonasson
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Ophthalmology 112:132-8. 2005
    ..To examine the age- and gender-specific 5-year incidence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik...
  3. ncbi request reprint Sveinsson chorioretinal atrophy: the mildest changes are located in the photoreceptor outer segment/retinal pigment epithelium junction
    Fridbert Jonasson
    Department of Ophthalmology, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Acta Ophthalmol Scand 85:862-7. 2007
    ..To locate the mildest and/or earliest changes in the retina and/or choroid in Sveinsson chorioretinal atrophy (SCRA), using more advanced techniques than previous studies...
  4. doi request reprint From epidemiology to lysyl oxidase like one (LOXL1) polymorphisms discovery: phenotyping and genotyping exfoliation syndrome and exfoliation glaucoma in Iceland
    Fridbert Jonasson
    University of Iceland, Landspitali, Reykjavik, Iceland
    Acta Ophthalmol 87:478-87. 2009
    ..These results have now largely been replicated world-wide...
  5. ncbi request reprint The prevalence of age-related maculopathy in iceland: Reykjavik eye study
    Fridbert Jonasson
    Department of Ophthalmology, University Iceland, Reykjavik, Iceland
    Arch Ophthalmol 121:379-85. 2003
    ..To examine the age- and sex-specific prevalence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik, Iceland, who were 50 years and older...
  6. ncbi request reprint Risk factors for five-year incident age-related macular degeneration: the Reykjavik Eye Study
    Arsaell Arnarsson
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Am J Ophthalmol 142:419-28. 2006
    ..To establish risk factors for five-year incidence of age-related macular degeneration (AMD)...
  7. doi request reprint Pseudoexfoliation in the reykjavik eye study: five-year incidence and changes in related ophthalmologic variables
    Arsaell Arnarsson
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Am J Ophthalmol 148:291-7. 2009
    ..To examine the 5-year incidence of pseudoexfoliation (PEX) and monitor changes in related ophthalmologic variables...
  8. ncbi request reprint Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables
    Arsaell Arnarsson
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Acta Ophthalmol Scand 85:822-7. 2007
    ..To examine the age and sex-specific prevalence of pseudoexfoliation syndrome (PEX) and its relationship with some ophthalmological variables...
  9. doi request reprint Population-based incidence of exudative age-related macular degeneration and ranibizumab treatment load
    Asbjorg Geirsdottir
    Department of Ophthalmology, Landspitali The National University Hospital of Iceland, Reykjavik, Iceland
    Br J Ophthalmol 96:444-7. 2012
    ..The authors study the population-based incidence of exudative AMD in Iceland and the use of intravitreal ranibizumab in a defined population...
  10. doi request reprint Exfoliation syndrome in the Reykjavik Eye Study: risk factors for baseline prevalence and 5-year incidence
    Arsaell Arnarsson
    Department of Ophthalmology, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Br J Ophthalmol 94:831-5. 2010
    ..To examine the age- and gender-specific prevalent and 5-year incident risk of developing exfoliation syndrome (XFS)...
  11. doi request reprint Five-year incidence of visual impairment and blindness in older Icelanders: the Reykjavik Eye Study
    Elin Gunnlaugsdottir
    Department of Ophthalmology, University of Iceland, Iceland
    Acta Ophthalmol 88:358-66. 2010
    ..This study examined age, sex and cause-specific 5-year incidence of visual impairment and blindness in a middle-aged and elderly Icelandic population...
  12. doi request reprint Prevalence and causes of visual impairment and blindness in Icelanders aged 50 years and older: the Reykjavik Eye Study
    Elin Gunnlaugsdottir
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Acta Ophthalmol 86:778-85. 2008
    ..This study aimed to study the prevalences and causes of visual impairment and blindness in an Icelandic adult population...
  13. ncbi request reprint Prevalence and risk factors for cornea guttata in the Reykjavik Eye Study
    Gunnar M Zoega
    Department of Ophthalmology, Landspitali University Hospital, Reykjavik, Iceland
    Ophthalmology 113:565-9. 2006
    ..To establish the age- and gender-specific prevalence of cornea guttata (CG) in citizens of Reykjavik, Iceland, 55 years and older...
  14. doi request reprint A rare nonsynonymous sequence variant in C3 is associated with high risk of age-related macular degeneration
    Hannes Helgason
    1 deCODE Genetics Amgen, Reykjavik, Iceland 2 School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland 3
    Nat Genet 45:1371-4. 2013
    ..Lys155Gln substitution reduces C3b binding to complement factor H, potentially creating resistance to inhibition by this factor. This resistance to inhibition in turn is predicted to result in enhanced complement activation...
  15. pmc CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD
    Kristinn P Magnusson
    deCODE Genetics, Reykjavik, Iceland
    PLoS Med 3:e5. 2006
    ..However, its impact on soft drusen, GA, or neovascular AMD--or the relationship between them--is unclear...
  16. ncbi request reprint Age-related macular degeneration in very old individuals with family history
    Asbjorg Geirsdottir
    Department of Ophthalmology, Landspitali University Hospital, Reykjavik, Iceland
    Am J Ophthalmol 143:889-90. 2007
    ..To study age-related macular degeneration (AMD) in old and very old individuals with family history of AMD to find the proportion of those with early and advanced AMD...
  17. ncbi request reprint Five-year refractive changes in an adult population: Reykjavik Eye Study
    Elinborg Gudmundsdottir
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Ophthalmology 112:672-7. 2005
    ..To study refractive changes over the course of 5 years in citizens of Reykjavik 50 years and older at baseline...
  18. ncbi request reprint Relationships between ocular dimensions and adult stature among participants in the Reykjavik Eye Study
    Thor Eysteinsson
    Department of Ophthalmology, University of Iceland, Reykjavik, Iceland
    Acta Ophthalmol Scand 83:734-8. 2005
    ..To examine the relationships between adult stature, age and ocular dimensions in a large homogenous, white population...
  19. ncbi request reprint Risk factors for nuclear lens opacification: the Reykjavik Eye Study
    Arsaell Arnarsson
    Department of Ophthalmology, University Hospital, Reykjavik, Iceland
    Dev Ophthalmol 35:12-20. 2002
    ..The purpose of this study is to examine risk factors for nuclear lens opacification in citizens of Reykjavik...
  20. ncbi request reprint Central corneal thickness, radius of the corneal curvature and intraocular pressure in normal subjects using non-contact techniques: Reykjavik Eye Study
    Thor Eysteinsson
    Department of Ophthalmology, National University Hospital, University of Iceland, Iceland
    Acta Ophthalmol Scand 80:11-5. 2002
    ..To establish a population profile of central corneal thickness (CCT), radius of the corneal curvature (CC) and intraocular pressure (IOP) and the relationships between them using non-contact techniques...
  21. ncbi request reprint Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study
    Vilhjalmur Rafnsson
    Department of Preventive Medicine, University of Iceland, Neshagi 16, 107 Reykjavik, Iceland
    Arch Ophthalmol 123:1102-5. 2005
    ..Aviation involves exposure to ionizing radiation of cosmic origin. The association between lesions of the ocular lens and ionizing radiation is well-known...
  22. ncbi request reprint Sveinsson chorioretinal atrophy/helicoid peripapillary chorioretinal degeneration: first histopathology report
    Fridbert Jonasson
    Department of Ophthalmology, Landspitali University Hospital and Faculty of Medicine, University of Iceland, Reykjavik, Iceland
    Ophthalmology 114:1541-6. 2007
    ..To report the histopathologic features in an eye with Sveinsson chorioretinal atrophy (SCRA), also termed helicoid peripapillary chorioretinal degeneration, for the first time...
  23. ncbi request reprint [New drug treatment for age-related macular degeneration]
    Einar Stefansson
    Laeknalid Háskóla Islands
    Laeknabladid 93:299-301. 2007
    ..Vascular endothelial growth factor antibodies reduce the risk of blindness and improve vision in patients with age-related macular degeneration...
  24. doi request reprint The 7-year cumulative incidence of cornea guttata and morphological changes in the corneal endothelium in the Reykjavik Eye Study
    Gunnar M Zoega
    Gullstrand lab, Ophthalmology, Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Acta Ophthalmol 91:212-8. 2013
    ..To examine the corneal endothelium and establish the 7-year cumulative incidence of cornea guttata (CG)...
  25. pmc Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma
    Gudmar Thorleifsson
    deCODE Genetics Inc, Reykjavik, Iceland
    Nat Genet 42:906-9. 2010
    ..42, P = 0.0021). The risk variant identified here is located close to CAV1 and CAV2, both of which are expressed in the trabecular meshwork and retinal ganglion cells that are involved in the pathogenesis of POAG...
  26. ncbi request reprint Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma
    Gudmar Thorleifsson
    deCODE Genetics Inc, 101 Reykjavik, Iceland
    Science 317:1397-400. 2007
    ..The population-attributable risk is more than 99%. The product of LOXL1 catalyzes the formation of elastin fibers found to be a major component of the lesions in XFG...
  27. ncbi request reprint High prevalence of nuclear cataract in the population of tropical and subtropical areas
    Hiroshi Sasaki
    Department of Ophthalmology, Kanazawa Medical University, Uchinada
    Dev Ophthalmol 35:60-9. 2002
    ....
  28. ncbi request reprint Increased disk size in glaucomatous eyes vs normal eyes in the Reykjavik eye study
    Lan Wang
    University of Ottawa Eye Institute, Ottawa, Ontario, Canada
    Am J Ophthalmol 135:226-8. 2003
    ..To evaluate the use of disk diameter as an indicator in the identification of glaucomatous optic neuropathy...
  29. ncbi request reprint Localization of cortical cataract in subjects of diverse races and latitude
    Hiroshi Sasaki
    Department of Ophthalmology, Kanazawa Medical University, Ishikawa, Japan
    Invest Ophthalmol Vis Sci 44:4210-4. 2003
    ..To compare the characteristics of early cortical cataract localization in three groups in cataract epidemiologic surveys performed in Reykjavík, Melbourne, and Singapore...
  30. ncbi request reprint A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration)
    Ragnheidur Fossdal
    deCODE Genetics, IS 101 Reykjavik, Iceland
    Hum Mol Genet 13:975-81. 2004
    ..Therefore, we conclude that the mutation in the TEAD1 gene is the cause of Sveinsson's chorioretinal atrophy...
  31. ncbi request reprint Racial differences of lens transparency properties with aging and prevalence of age-related cataract applying a WHO classification system
    Kazuyuki Sasaki
    Department of Ophthalmology, Kanazawa Medical University, Uchinada, Japan
    Ophthalmic Res 36:332-40. 2004
    ..To investigate racial differences of lens transparency properties and the prevalence of lens opacification by age...
  32. ncbi request reprint Macular corneal dystrophy types I and II are caused by distinct mutations in the CHST6 gene in Iceland
    Ning pu Liu
    Beijing Tongren Eye Center, Capital University of Medical Sciences, Beijing, China
    Mol Vis 12:1148-52. 2006
    ..To identify CHST6 mutations in five additional Icelandic cases of macular corneal dystrophy (MCD) type I and in four families with MCD type II from Iceland...
  33. doi request reprint Retinal and cerebral microvascular signs and diabetes: the age, gene/environment susceptibility-Reykjavik study
    Chengxuan Qiu
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health NIH, Bethesda, Maryland 20892, USA
    Diabetes 57:1645-50. 2008
    ..We sought to examine whether microvascular lesions in the retina and in the brain are associated and whether this association differs among people with and without diabetes...
  34. ncbi request reprint Solving the enigma of exfoliation glaucoma: a breakthrough in glaucoma research
    Fridbert Jonasson
    Acta Ophthalmol Scand 85:808-9. 2007
  35. ncbi request reprint Genetic determinants of hair, eye and skin pigmentation in Europeans
    Patrick Sulem
    deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland
    Nat Genet 39:1443-52. 2007
    ..3 is associated with freckles. The fifth region provided refinements to a previously reported association in OCA2, and the sixth encompasses previously described variants in MC1R...
  36. ncbi request reprint On the ocular refractive components: the Reykjavik Eye Study
    Thomas Olsen
    University Eye Clinic, Aarhus Kommunehospital, Aarhus, Denmark
    Acta Ophthalmol Scand 85:361-6. 2007
    ..To study the correlation between ocular refraction and the refractive components (corneal power, lens power and axial length) in a population-based sample of normal subjects...