A A Hussain

Summary

Publications

  1. doi request reprint Macromolecular diffusion characteristics of ageing human Bruch's membrane: implications for age-related macular degeneration (AMD)
    A A Hussain
    Department of Ophthalmology, King s College London, The Rayne Institute, St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, United Kingdom
    Exp Eye Res 90:703-10. 2010
  2. doi request reprint High molecular-weight gelatinase species of human Bruch's membrane: compositional analyses and age-related changes
    Ali A Hussain
    Department of Ophthalmology, King s College London, St Thomas Hospital, London, United Kingdom
    Invest Ophthalmol Vis Sci 51:2363-71. 2010
  3. ncbi request reprint Age-related alterations in the diffusional transport of amino acids across the human Bruch's-choroid complex
    Ali A Hussain
    Department of Ophthalmology, The Guy s, King s and St Thomas Hospitals Medical and Dental School, King s College London, United Kingdom
    J Opt Soc Am A Opt Image Sci Vis 19:166-72. 2002
  4. ncbi request reprint Age-dependent variation in metalloproteinase activity of isolated human Bruch's membrane and choroid
    L Guo
    Department of Ophthalmology, The Guy s, King s and St Thomas Hospitals Medical and Dental School, King s College London, United Kingdom
    Invest Ophthalmol Vis Sci 40:2676-82. 1999
  5. pmc An experimental study of the elastic properties of the human Bruch's membrane-choroid complex: relevance to ageing
    M Ugarte
    Department of Ophthalmology, St Thomas s Hospital, London, UK
    Br J Ophthalmol 90:621-6. 2006
  6. ncbi request reprint Hydraulic conductivity of fixed retinal tissue after sequential excimer laser ablation: barriers limiting fluid distribution and implications for cystoid macular edema
    R J Antcliff
    GKT Department of Ophthalmology, The Rayne Institute, Saint Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, England
    Arch Ophthalmol 119:539-44. 2001
  7. ncbi request reprint The influence of path length and matrix components on ageing characteristics of transport between the choroid and the outer retina
    Jost Hillenkamp
    Department of Ophthalmology, The Rayne Institute, St Thomas Hospital, London, United Kingdom
    Invest Ophthalmol Vis Sci 45:1493-8. 2004
  8. ncbi request reprint Taurine uptake by human retinal pigment epithelium: implications for the transport of small solutes between the choroid and the outer retina
    Jost Hillenkamp
    Department of Ophthalmology, The Rayne Institute, St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, UK
    Invest Ophthalmol Vis Sci 45:4529-34. 2004
  9. ncbi request reprint Compartmental analysis of taurine transport to the outer retina in the bovine eye
    Jost Hillenkamp
    Department of Ophthalmology, The Rayne Institute, St Thomas Hospital, London, UK
    Invest Ophthalmol Vis Sci 45:4099-105. 2004
  10. ncbi request reprint Expression of metalloproteinases from human retinal pigment epithelial cells and their effects on the hydraulic conductivity of Bruch's membrane
    Alpa Ahir
    Department of Ophthalmology, The Guy s, King s and St Thomas Hospitals Medical and Dental School, King s College London, St Thomas Campus, Lambeth Palace Road, London, United Kingdom
    Invest Ophthalmol Vis Sci 43:458-65. 2002

Collaborators

Detail Information

Publications11

  1. doi request reprint Macromolecular diffusion characteristics of ageing human Bruch's membrane: implications for age-related macular degeneration (AMD)
    A A Hussain
    Department of Ophthalmology, King s College London, The Rayne Institute, St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, United Kingdom
    Exp Eye Res 90:703-10. 2010
    ....
  2. doi request reprint High molecular-weight gelatinase species of human Bruch's membrane: compositional analyses and age-related changes
    Ali A Hussain
    Department of Ophthalmology, King s College London, St Thomas Hospital, London, United Kingdom
    Invest Ophthalmol Vis Sci 51:2363-71. 2010
    ..The purpose of this study was to determine the age-related changes in levels of expression and subunit characterization of the HMW gelatinase species of Bruch's membrane...
  3. ncbi request reprint Age-related alterations in the diffusional transport of amino acids across the human Bruch's-choroid complex
    Ali A Hussain
    Department of Ophthalmology, The Guy s, King s and St Thomas Hospitals Medical and Dental School, King s College London, United Kingdom
    J Opt Soc Am A Opt Image Sci Vis 19:166-72. 2002
    ..The importance of this reduction in delivery of amino acids is discussed with reference to both normal physiology and age-related macular degeneration...
  4. ncbi request reprint Age-dependent variation in metalloproteinase activity of isolated human Bruch's membrane and choroid
    L Guo
    Department of Ophthalmology, The Guy s, King s and St Thomas Hospitals Medical and Dental School, King s College London, United Kingdom
    Invest Ophthalmol Vis Sci 40:2676-82. 1999
    ..To characterize and determine the effect of aging on the matrix metalloproteinase (MMP) component of the extracellular matrix-remodeling mechanism of isolated human Bruch's-choroid...
  5. pmc An experimental study of the elastic properties of the human Bruch's membrane-choroid complex: relevance to ageing
    M Ugarte
    Department of Ophthalmology, St Thomas s Hospital, London, UK
    Br J Ophthalmol 90:621-6. 2006
    ....
  6. ncbi request reprint Hydraulic conductivity of fixed retinal tissue after sequential excimer laser ablation: barriers limiting fluid distribution and implications for cystoid macular edema
    R J Antcliff
    GKT Department of Ophthalmology, The Rayne Institute, Saint Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, England
    Arch Ophthalmol 119:539-44. 2001
    ..CLINICAL RELEVANCE: These observations help to explain the distribution of cystoid macular edema seen in histological studies and with optical coherence tomography...
  7. ncbi request reprint The influence of path length and matrix components on ageing characteristics of transport between the choroid and the outer retina
    Jost Hillenkamp
    Department of Ophthalmology, The Rayne Institute, St Thomas Hospital, London, United Kingdom
    Invest Ophthalmol Vis Sci 45:1493-8. 2004
    ..To determine the relative influence of path length and matrix components on the movement of small solutes and water between the choroid and the outer retina...
  8. ncbi request reprint Taurine uptake by human retinal pigment epithelium: implications for the transport of small solutes between the choroid and the outer retina
    Jost Hillenkamp
    Department of Ophthalmology, The Rayne Institute, St Thomas Hospital, Lambeth Palace Road, London SE1 7EH, UK
    Invest Ophthalmol Vis Sci 45:4529-34. 2004
    ..To identify the rate limiting compartment in the pathway of taurine delivery from the choroidal blood supply to the outer retina composed by Bruch's-choroid (BC) and the RPE in the human older age group...
  9. ncbi request reprint Compartmental analysis of taurine transport to the outer retina in the bovine eye
    Jost Hillenkamp
    Department of Ophthalmology, The Rayne Institute, St Thomas Hospital, London, UK
    Invest Ophthalmol Vis Sci 45:4099-105. 2004
    ..To quantify the effect of light-evoked changes in subretinal potassium concentration on the transepithelial transport of taurine across bovine RPE...
  10. ncbi request reprint Expression of metalloproteinases from human retinal pigment epithelial cells and their effects on the hydraulic conductivity of Bruch's membrane
    Alpa Ahir
    Department of Ophthalmology, The Guy s, King s and St Thomas Hospitals Medical and Dental School, King s College London, St Thomas Campus, Lambeth Palace Road, London, United Kingdom
    Invest Ophthalmol Vis Sci 43:458-65. 2002
    ..To evaluate the expression pattern of matrix metalloproteinases (MMPs) from retinal pigment epithelial (RPE) cells in culture, and to determine their ability to alter the transport properties of human Bruch's membrane...
  11. doi request reprint Human transscleral albumin permeability and the effect of topographical location and donor age
    Owen A Anderson
    KCL Department of Ophthalmology, The Rayne Institute, St Thomas Hospital, London, United Kingdom
    Invest Ophthalmol Vis Sci 49:4041-5. 2008
    ..To quantify the permeability coefficient of albumin across human sclera and to assess topographical and age-related variation...