G Telegdy

Summary

Affiliation: University of Szeged
Country: Hungary

Publications

  1. ncbi request reprint The action of orexin A on passive avoidance learning. Involvement of transmitters
    G Telegdy
    Department of Pathophysiology, Medical School, Neurohumoral Research Group of the Hungarian Academy of Sciences, University of Szeged, 6701 Semmelweis l, H 6721, Szeged, Hungary
    Regul Pept 104:105-10. 2002
  2. doi request reprint Involvement of transmitters in the anxiolytic action of urocortin 3 in mice
    G Telegdy
    Department of Pathophysiology, University of Szeged, MTA SZTE Neurohumoral Research Group, P O Box 427, H 6701 Szeged, Hungary Electronic address
    Behav Brain Res 252:88-91. 2013
  3. doi request reprint The action of kisspeptin-13 on passive avoidance learning in mice. Involvement of transmitters
    Gyula Telegdy
    Department of Pathophysiology, Faculty of Medicine, University of Szeged, Szeged, Hungary
    Behav Brain Res 243:300-5. 2013
  4. doi request reprint Involvement of neurotransmitters in the action of apelin-13 on passive avoidance learning in mice
    Gyula Telegdy
    Department of Pathophysiology, University of Szeged, Szeged, Hungary
    Peptides 39:171-4. 2013
  5. doi request reprint Involvement of neurotransmitters in the action of growth hormone-releasing hormone antagonist on passive avoidance learning
    Gyula Telegdy
    Department of Pathophysiology, Neuroscience Research Group of the Hungarian Academy of Sciences, University of Szeged, Szeged, Hungary
    Behav Brain Res 233:326-30. 2012
  6. doi request reprint Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice
    Gyula Telegdy
    Department of Pathophysiology, Neuroscience Group of the Hungarian Academy of Sciences, University of Szeged, Szeged, Hungary
    Behav Brain Res 233:232-6. 2012
  7. pmc The effects of isatin (indole-2, 3-dione) on pituitary adenylate cyclase-activating polypeptide-induced hyperthermia in rats
    Imre Pataki
    Hungarian Academy of Sciences Neurohumoral Research Group, Department of Pathophysiology, University of Szeged, Semmelweis u, 1, Szeged, Hungary
    BMC Neurosci 3:2. 2002
  8. doi request reprint Effects of the LHRH antagonist Cetrorelix on affective and cognitive functions in rats
    G Telegdy
    Department of Pathophysiology, University of Szeged, Hungary
    Regul Pept 159:142-7. 2010
  9. ncbi request reprint The action of pituitary adenylate cyclase activating polypeptide (PACAP) on passive avoidance learning. The role of transmitters
    G Telegdy
    Institute of Pathophysiology, A Szent Györgyi Medical University, Semmelweis str 1, POB 531, 6701, Szeged, Hungary
    Brain Res 874:194-9. 2000
  10. ncbi request reprint Involvement of neurotransmitters in urocortin-induced passive avoidance learning in mice
    G Telegdy
    Institute of Pathophysiology, Neurohumoral Research Group of the Hungarian Academy of Sciences, University of Szeged, H 6701 Szeged, Hungary
    Brain Res Bull 67:242-7. 2005

Collaborators

Detail Information

Publications44

  1. ncbi request reprint The action of orexin A on passive avoidance learning. Involvement of transmitters
    G Telegdy
    Department of Pathophysiology, Medical School, Neurohumoral Research Group of the Hungarian Academy of Sciences, University of Szeged, 6701 Semmelweis l, H 6721, Szeged, Hungary
    Regul Pept 104:105-10. 2002
    ..A number of transmitters could be involved in the action of consolidation, but none of them is absolutely essential...
  2. doi request reprint Involvement of transmitters in the anxiolytic action of urocortin 3 in mice
    G Telegdy
    Department of Pathophysiology, University of Szeged, MTA SZTE Neurohumoral Research Group, P O Box 427, H 6701 Szeged, Hungary Electronic address
    Behav Brain Res 252:88-91. 2013
    ..The results suggest that dopaminergic, beta-adrenergic, cholinergic, serotonergic and opiate transmissions are involved in the anxiolytic action of Ucn 3. ..
  3. doi request reprint The action of kisspeptin-13 on passive avoidance learning in mice. Involvement of transmitters
    Gyula Telegdy
    Department of Pathophysiology, Faculty of Medicine, University of Szeged, Szeged, Hungary
    Behav Brain Res 243:300-5. 2013
    ....
  4. doi request reprint Involvement of neurotransmitters in the action of apelin-13 on passive avoidance learning in mice
    Gyula Telegdy
    Department of Pathophysiology, University of Szeged, Szeged, Hungary
    Peptides 39:171-4. 2013
    ..The data suggest that apelin-13 elicits its action on the consolidation of passive avoidance learning via α-adrenergic, 5-HT2 serotonergic, cholinergic, dopaminergic, GABA-A-ergic and nitric oxide mediations...
  5. doi request reprint Involvement of neurotransmitters in the action of growth hormone-releasing hormone antagonist on passive avoidance learning
    Gyula Telegdy
    Department of Pathophysiology, Neuroscience Research Group of the Hungarian Academy of Sciences, University of Szeged, Szeged, Hungary
    Behav Brain Res 233:326-30. 2012
    ..The results demonstrate that the muscarinic acetylcholine receptor, the 5-HT1/5-HT2 serotonergic receptor and opioid receptors are involved as mediators in the action of MZ-4-71 on the consolidation of passive avoidance learning...
  6. doi request reprint Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice
    Gyula Telegdy
    Department of Pathophysiology, Neuroscience Group of the Hungarian Academy of Sciences, University of Szeged, Szeged, Hungary
    Behav Brain Res 233:232-6. 2012
    ....
  7. pmc The effects of isatin (indole-2, 3-dione) on pituitary adenylate cyclase-activating polypeptide-induced hyperthermia in rats
    Imre Pataki
    Hungarian Academy of Sciences Neurohumoral Research Group, Department of Pathophysiology, University of Szeged, Semmelweis u, 1, Szeged, Hungary
    BMC Neurosci 3:2. 2002
    ..In this study the aim was to investigate the effects of isatin on thermoregulatory actions of PACAP-38, in rats...
  8. doi request reprint Effects of the LHRH antagonist Cetrorelix on affective and cognitive functions in rats
    G Telegdy
    Department of Pathophysiology, University of Szeged, Hungary
    Regul Pept 159:142-7. 2010
    ..Collectively our findings confirm the effects of Cetrorelix on brain function in two species and suggest the possible merit of a clinical trial with Cetrorelix in patients with anxiety, depression and Alzheimer's disease...
  9. ncbi request reprint The action of pituitary adenylate cyclase activating polypeptide (PACAP) on passive avoidance learning. The role of transmitters
    G Telegdy
    Institute of Pathophysiology, A Szent Györgyi Medical University, Semmelweis str 1, POB 531, 6701, Szeged, Hungary
    Brain Res 874:194-9. 2000
    ..In this action, the PACAP 38 receptor and NO are important mediators. Dopaminergic, alpha- and beta-adrenergic mediation and serotonin receptors modified the action of PACAP 38, but they are probably not of great importance...
  10. ncbi request reprint Involvement of neurotransmitters in urocortin-induced passive avoidance learning in mice
    G Telegdy
    Institute of Pathophysiology, Neurohumoral Research Group of the Hungarian Academy of Sciences, University of Szeged, H 6701 Szeged, Hungary
    Brain Res Bull 67:242-7. 2005
    ..D2, muscarinic cholinergic, alfa-adrenergic, CRF, serotonergic (5HT 1-2), GABA B receptors are involved in the consolidation of the passive avoidance response...
  11. ncbi request reprint The action of urocortins on body temperature in rats
    G Telegdy
    Department of Pathophysiology, Neurohumoral Research Group of the Hungarian Academy of Sciences, Semmelweis 1, Szeged H 6701, Hungary
    Peptides 27:2289-94. 2006
    ..The cyclooxygenase inhibitor blocked or diminished the action of these urocortins, indicating the involvement of prostaglandins in urocortin-induced hyperthermia...
  12. doi request reprint Involvement of CRH receptors in urocortin-induced hyperthermia
    G Telegdy
    Department of Pathophysiology, University of Szeged, Semmelweis 1, Szeged 6701, Hungary
    Peptides 29:1937-42. 2008
    ..The action of urocortin 1 is mediated by CRHR1 receptor, while in the action of urocortin 2 and urocortin 3 CRHR2 receptor is involved...
  13. doi request reprint Effects of the LHRH antagonist Cetrorelix on the brain function in mice
    Gyula Telegdy
    Department of Pathophysiology, University of Szeged, Semmelweis 1, 6701 Szeged, Csongrad, Hungary
    Neuropeptides 43:229-34. 2009
    ..Further experimental work with Cetrorelix is necessary, but the results imply the possible merit of a clinical trial with Cetrorelix in patients with anxiety, depression and Alzheimer's disease...
  14. doi request reprint Anxiolytic action of urocortin 3 fragments in mice
    G Telegdy
    University of Szeged, Faculty of Medicine, Department of Pathophysiology, Semmelweis 1, Szeged, Hungary
    Behav Brain Res 222:295-8. 2011
    ..The results indicate that the total sequence of Ucn 3 is not necessary for the anxiolytic action of Ucn 3. Establishment the smallest active sequence of Ucn 3 will allow the synthesis of analogs or mimetics for anxiolytic action...
  15. doi request reprint Effects of the growth hormone-releasing hormone (GH-RH) antagonist on brain functions in mice
    Gyula Telegdy
    Department of Pathophysiology, University of Szeged, Hungary
    Behav Brain Res 224:155-8. 2011
    ..The results imply a possible merit of a clinical trial with MZ-4-71 in patients with anxiety, depression and cognitive impairment, as observed in Alzheimer's disease...
  16. ncbi request reprint The action of isatin (2,3-dioxoindole) an endogenous indole on brain natriuretic and C-type natriuretic peptide-induced facilitation of memory consolidation in passive-avoidance learning in rats
    G Telegdy
    Institute of Pathophysiology, University of Szeged, Szeged, Hungary
    Brain Res Bull 53:367-70. 2000
    ..Isatin reduced the effect of both BNP and CNP; this was significant for its effect on BNP at 50 mg/kg and on CNP at both 10 and 50 mg/kg. These results show that isatin can inhibit behavioural effects of BNP and CNP as well as ANP...
  17. ncbi request reprint Behavioral, neuroendocrine and thermoregulatory actions of apelin-13
    M Jászberényi
    Department of Pathophysiology, University of Szeged, Neurohumoral Research Group, Hungarian Academy of Sciences, Semmelweis u 1, PO Box 427, H 6701, Szeged, Hungary
    Neuroscience 129:811-6. 2004
    ..Since the corticosterone response could be blocked by the CRH antagonist, it is likely to be mediated through the activation of the CRH neurons...
  18. ncbi request reprint Mediation of the behavioral, endocrine and thermoregulatory actions of ghrelin
    M Jászberényi
    Department of Pathophysiology, University of Szeged, Neurohumoral Research Group, Hungarian Academy of Sciences, PO Box 427, Semmelweis u 1, H 6701 Szeged, Hungary
    Horm Behav 50:266-73. 2006
    ..On the other hand, ghrelin appears to have an impact on the HPA response via a serotonergic pathway and on the hyperthermic response via a cyclooxygenase and a serotonergic pathway...
  19. ncbi request reprint Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF
    E Bujdosó
    Department of Pathophysiology, University of Szeged, Neurohumoral Research Group, Hungarian Academy of Sciences, Szeged, Hungary
    Horm Behav 43:302-11. 2003
    ..MERF also appears to activate the paraventricular CRH neurons, but dopaminergic transmission does not seem to play a significant role in its hypothalamic action...
  20. ncbi request reprint Behavioral and neuroendocrine actions of endomorphin-2
    E Bujdosó
    Department of Pathophysiology, University of Szeged, Neurohumoral Research Group, Hungarian Academy of Sciences, Szeged, Hungary
    Peptides 22:1459-63. 2001
    ..These findings reinforce the hypothesis that the endomorphins may play a significant role in the regulation of locomotion, rearing activity and the HPA system through the release of CRH...
  21. doi request reprint Neurotransmission of the antidepressant-like effects of the growth hormone-releasing hormone antagonist MZ-4-71
    M Tanaka
    Department of Pathophysiology, Faculty of Medicine, University of Szeged, Szeged, Hungary
    Behav Brain Res 228:388-91. 2012
    ....
  22. ncbi request reprint The role of neuropeptide Y in orexin-induced hypothalamic-pituitary-adrenal activation
    M Jászberényi
    Department of Pathophysiology, Albert Szent Györgyi Medical and Pharmaceutical Centre, University of Szeged, MTA SZTE Neurohumoral Research Group, Hungary
    J Neuroendocrinol 13:438-41. 2001
    ..These data suggest that the HPA system-stimulating effect of the orexins may be mediated by NPY...
  23. ncbi request reprint Involvement of different receptors in pituitary adenylate cyclase activating polypeptide induced open field activity in rats
    A Adamik
    Department of Pathophysiology, Neurohumoral Research Group of the Hungarian Academy of Sciences, University of Szeged, H 6701 Szeged, Hungary
    Neuropeptides 38:16-20. 2004
    ..Atropine, nitro-l-arginine, bicuculline and methysergide were ineffective. The data demonstrate that the action of PACAP 38 on the open-field activity is regulated by D2, alpha- and beta-adrenergic and opiate receptors...
  24. ncbi request reprint The effects of brain and C-type natriuretic peptides on corticotropin-releasing factor in brain of rats
    J Gardi
    Endocrine Unit, Albert Szent Györgi Medical University, Szeged, Hungary
    Life Sci 60:2111-7. 1997
    ..The CRF-LI increased in the basal forebrain after a low dose (100 ng) of CNP. These results suggest that CRF may be involved in the mediation of some neuroendocrine and behavioral responses to BNP and CNP...
  25. ncbi request reprint Platelet eicosanoids and the effect of captopril in blood pressure regulation
    Z Mezei
    Department of Pathophysiology, Albert Szent Gyorgyi Medical University, Szeged, Hungary
    Eur J Pharmacol 340:67-73. 1997
    ..We may conclude that, in spite of the missing angiotensin converting enzyme in platelets, a direct effect on platelet eicosanoid synthesis could contribute to the blood pressure decreasing effect of captopril...
  26. ncbi request reprint The involvement of dopamine and nitric oxide in the endocrine and behavioural action of endomorphin-1
    E Bujdosó
    University of Szeged, Department of Pathophysiology, Albert Szent Györgyi Medical and Pharmaceutical Centre, Neurohumoral Research Group of Hungarian Academy of Sciences, PO Box 427, 6701 Szeged, Hungary
    Neuroscience 120:261-8. 2003
    ..In contrast, the behavioural experiments reflect that the locomotor activation induced by EM1 is mediated by NO and dopamine, and the superfusion studies demonstrate that NO transmits the dopamine release enhancing effect of EM1...
  27. ncbi request reprint Effects of endomorphin-1 on open-field behavior and on the hypothalamic-pituitary-adrenal system
    E Bujdosó
    Department of Pathophysiology, University of Szeged, Albert Szent Gyorgyi Medical and Pharmaceutical Center, Hungary
    Endocrine 14:221-4. 2001
    ..These results suggest that the EM1 -induced increases in locomotion and rearing activity as well as the pituitary-adrenal activation are mediated by CRH...
  28. ncbi request reprint The role of nitric oxide in passive avoidance learning
    G Telegdy
    Department of Pathophysiology, Albert Szent Gyorgyi Medical University, Szeged, Hungary
    Neuropharmacology 36:1583-7. 1997
    ....
  29. ncbi request reprint Brain monoamines are involved in mediating the action of neurohypophyseal peptide hormones on ethanol tolerance
    G Szabo
    Department of Pathophysiology, University Medical School, Szeged, Hungary
    Acta Physiol Hung 71:459-66. 1988
    ..The data suggest that the central monoamines may be involved in mediating the actions of neurohypophyseal peptides on ethanol tolerance...
  30. ncbi request reprint Vasoactive substances produced by cultured rat brain endothelial cells
    B Kis
    Department of Pathophysiology, Albert Szent Gyorgyi Medical University, Szeged, Hungary
    Eur J Pharmacol 368:35-42. 1999
    ..The capacity of cerebral endothelium to regulate vascular tone by production of dilator and constrictor substances can be preserved under certain circumstances in immortalized cell lines...
  31. ncbi request reprint The effects of valproate on the arachidonic acid metabolism of rat brain microvessels and of platelets
    Z Szupera
    Department of Neurology, Albert Szent Gyorgyi Medical University, P O Box 397, H 6701, Szeged, Hungary
    Eur J Pharmacol 387:205-10. 2000
    ..Modifications of the arachidonate cascade in platelets and brain microvessels may contribute to the cell function alterations caused by valproate...
  32. ncbi request reprint Action of C-type natriuretic peptide (CNP) on passive avoidance learning in rats: involvement of transmitters
    G Telegdy
    Department of Pathophysiology, MTA SZOTE Neurohumoral Research Group, Albert Szent Gyorgyi Medical University, Szeged, Hungary
    Eur J Neurosci 11:3302-6. 1999
    ..In the action of CNP, dopamine, acetylcholine and nitric oxide could be the mediating transmitters...
  33. ncbi request reprint The role of central corticoliberin in the hyperosmosis-induced secretion of neurohypophysial hormones and corticosterone in the rat
    F Laczi
    Endocrine Unit, , Szeged, Hungary
    Neuropeptides 27:15-8. 1994
    ..These findings suggest that the central CRH system may participate in the regulation of corticosterone and neurohypophysial hormone secretion evoked by acute osmotic challenge...
  34. doi request reprint Antidepressant-like effects of urocortin 3 fragments
    M Tanaka
    Department of Pathophysiology, Faculty of Medicine, University of Szeged, Semmelweis 1, Szeged, Hungary
    Brain Res Bull 84:414-8. 2011
    ..Establishment of the smallest active sequence of the molecule may allow the synthesis of analogs or mimetics for antidepressive drugs...
  35. ncbi request reprint Arachidonate cascade in mesenteric blood vessels and platelets of spontaneously hypertensive rats
    A Gecse
    Department of Pathophysiology, University Medical School of Szeged, Hungary
    Agents Actions Suppl 22:43-8. 1987
    ..The lipoxygenase pathway was more active in the platelets of SH animals than in the controls. Both in the mesenteric arteries and in the platelets, the arachidonate cascade might play some role in the pathogenesis of hypertension...
  36. ncbi request reprint Effects of inflammatory neuropeptides on the arachidonate cascade of platelets
    A Gecse
    Department of Pathophysiology, Albert Szent Gyorgyi Medical University, Szeged, Hungary
    Int Arch Allergy Immunol 118:166-70. 1999
    ..Platelets are one of the most important elements of the microcirculation...
  37. ncbi request reprint Time-dependent alterations in corticotropin-releasing factor-like immunoreactivity in different brain regions after acute cocaine administration to rats
    J Gardi
    Endocrine Unit, Albert Szent Gyorgyi Medical University, Szeged, Hungary
    Neuropeptides 31:15-8. 1997
    ..These results suggest that the durations of the effects of cocaine on CRF-LI are in the brain region-specific, which might contribute to the mediation of the diverse behavioral and neuroendocrine effects of cocaine...
  38. doi request reprint Neurotransmissions of antidepressant-like effects of kisspeptin-13
    M Tanaka
    Neuroscience Research Group of the Hungarian Academy of Science, University of Szeged, Szeged, Hungary
    Regul Pept 180:1-4. 2013
    ..The results demonstrated that the antidepressant-like effects of kisspeptin-13 in a modified mouse FST are mediated, at least in part, by an interaction of the α(2)-adrenergic and 5-HT(2) serotonergic receptors...
  39. ncbi request reprint Antiamnesic effects of D-pipecolic acid and analogues of Pro-Leu-Gly-NH2 in rats
    G L Kovacs
    Institute of Pathophysiology, University Medical School, Szeged, Hungary
    Pharmacol Biochem Behav 31:833-7. 1988
    ..Therefore, D-pipecolic acid, D-pipecolamide and their N-terminally protected analogues were also investigated, and were found to have powerful antiamnesic effects...
  40. ncbi request reprint Effects of neurohypophyseal hormones on food-reinforced classical conditioning in the rat
    R S Ibragimov
    Institute of Pathophysiology, University Medical School, Szeged, Hungary
    Acta Physiol Hung 71:303-13. 1988
    ..The present results indicate that the effects of LVP and OXT on memory display reinforcement-dependent characteristics, and are thus indirect or non-specific in nature...
  41. ncbi request reprint Platelet arachidonate cascade of migraineurs in the interictal phase
    Z Mezei
    Department of Pathophysiology, Albert Szent Gyorgyi Medical University, Szeged, Hungary
    Platelets 11:222-5. 2000
    ..These results suggest that the platelet eicosanoids of migraineurs in the headache-free period might promote the development of cellular, vascular and neurological events inducing headache...
  42. ncbi request reprint Vasoactive intestinal polypeptide induces analgesia and impairs the antinociceptive effect of morphine in mice
    M Macsai
    Department of Pathophysiology, Albert Szent Gyorgyi Medical University, Szeged, Hungary
    Neuropeptides 32:557-62. 1998
    ..Morphine withdrawal signs were not significantly affected after VIP pretreatment. These findings indicate that VIP may play a role in pain sensitivity and that an opiate component may participate in this effect...
  43. ncbi request reprint Prostanoid synthesis in the cerebral blood vessels of asphyxiated piglets
    B Kis
    Department of Pathophysiology, University of Szeged, Faculty of Medicine, Hungary
    Acta Physiol Hung 88:87-100. 2001
    ..These findings indicate that O2 ventilation after asphyxia substantially increases the extent of prostanoid synthesis in the cerebral blood vessels...
  44. ncbi request reprint Cyclic GMP excretion blocked by isatin administration under conditions of fluid overload
    A Medvedev
    Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, Russia
    Biochem Pharmacol 62:225-7. 2001
    ..Isatin thus affected both the generation of cGMP and fluid balance in vivo...