Research Topics
Species | Zoltan SzekaneczSummaryAffiliation: University of Debrecen Country: Hungary Publications
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Detail Information
Publications
Immunoperoxidase histochemistry for the detection of cellular adhesion molecule, cytokine, and chemokine expression in the arthritic synoviumZoltan Szekanecz
University of Debrecen, Hungary
Methods Mol Biol 225:283-90. 2003
Gastrointestinal manifestations in Hungarian scleroderma patientsSzilvia Szamosi
Division of Rheumatology, Third Department of Medicine, Institute for Medicine, Medical and Health Science Center, University of Debrecen, 22 Moricz Street, Debrecen 4004, Hungary
Rheumatol Int 26:1120-4. 2006..Our results support that GI manifestations are rather common in SSc. Apart from the esophagus, other GI complications in SSc are usually mild, however, early recognition is necessary to improve quality of life...
Associations between serum anti-CCP antibody, rheumatoid factor levels and HLA-DR4 expression in Hungarian patients with rheumatoid arthritisAniko Kapitany
Laboratory of Immunology, Third Department of Medicine, University of Debrecen Medical Centre, Debrecen, Hungary
Isr Med Assoc J 10:32-6. 2008..However, there is little information regarding a relationship between quantitative anti-CCP production (serum anti-CCP concentrations) and the shared epitope...
Effects of rituximab treatment on endothelial dysfunction, carotid atherosclerosis, and lipid profile in rheumatoid arthritisGyörgy Kerekes
Cardiovascular Unit, Third Department of Medicine, University of Debrecen Medical and Health Science Center, Moricz Zs Krt 22, 4032, Debrecen, Hungary
Clin Rheumatol 28:705-10. 2009..RTX may also decrease ccIMT; however, longer follow-up is needed to assess the prolonged effects of RTX on vascular function and lipid profile in RA patients...
New insights in synovial angiogenesisZoltan Szekanecz
Department of Rheumatology, Institute of Medicine, University of Debrecen Medical and Health Sciences Center, 98, Nagyerdei street, Debrecen, H 4032, Hungary
Joint Bone Spine 77:13-9. 2010..A complete review of antiangiogenic drugs used in animal models of arthritis or human RA is available in a table...
Vascular effects of biologic agents in RA and spondyloarthropathiesZoltan Szekanecz
Department of Rheumatology Institute of Medicine, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
Nat Rev Rheumatol 5:677-84. 2009..Preliminary data suggest that rituximab also improves endothelial function and dyslipidemia. Further studies are needed to determine the net effects of biologic agents on the vasculature...
Chemokine and chemokine receptor blockade in arthritis, a prototype of immune-mediated inflammatory diseasesZ Szekanecz
Department of Rheumatology, Institute of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, H 4004, Hungary
Neth J Med 69:356-66. 2011..Therefore, modulation of receptor occupancy may be a feasible option to increase the efficacy of chemokine receptor targeting...
Biologics - beyond the jointsZoltan Szekanecz
Department of Rheumatology, Institute of Medicine, University of Debrecen Medical and Health Science Center, Hungary
Autoimmun Rev 9:820-4. 2010..At present, we do not always have sufficient evidence to confirm these differences, therefore, more information should be obtained from large trials and long-term observational studies...
Malignancies in autoimmune rheumatic diseases - a mini-reviewZoltan Szekanecz
Department of Rheumatology, Institute of Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
Gerontology 57:3-10. 2011..Tumor-associated antigens may be produced by inflammatory cells and their production may be increased in rheumatoid arthritis and other autoimmune diseases...
Angiogenesis in rheumatoid arthritisZoltan Szekanecz
Department of Rheumatology, Institute of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, H 4032, Hungary
Autoimmunity 42:563-73. 2009..In addition, some naturally produced or synthetic compounds including angiostatin, endostatin, paclitaxel, fumagillin analogues, 2-methoxyestradiol and thalidomide may be included in the management of RA...
Angiogenesis and vasculogenesis in rheumatoid arthritisZoltan Szekanecz
Department of Rheumatology, Institute of Medicine, University of Debrecen Medical and Health Sciences Center, Hungary
Curr Opin Rheumatol 22:299-306. 2010..Current understanding of the role of angiogenesis and vasculogenesis in rheumatoid arthritis (RA) and possibilities of therapeutic intervention should be summarized...
Increased production of the soluble tumor-associated antigens CA19-9, CA125, and CA15-3 in rheumatoid arthritis: potential adhesion molecules in synovial inflammation?Eva Szekanecz
Department of Oncology, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
Ann N Y Acad Sci 1108:359-71. 2007..CEA, CA19-9, CA125, and CA15-3 contain carbohydrate motifs and thus they may be involved in synovitis-associated adhesive events. Furthermore, some TAAs, such as CEA, may also correlate with prognostic factors, such as serum RF levels...
Comparative assessment of vascular function in autoimmune rheumatic diseases: considerations of prevention and treatmentPal Soltesz
University of Debrecen Medical and Health Sciences Center, Institute of Medicine, Third Department of Medicine, Angiology and Intensive Care Unit, Debrecen, Hungary
Autoimmun Rev 10:416-25. 2011..The official EULAR recommendations on the assessment and management of cardiovascular disease in arthritides have just been published, and similar recommendations in connective tissue diseases are to be developed soon...
New classification of the shared epitope in rheumatoid arthritis: impact on the production of various anti-citrullinated protein antibodiesAgnes Gyetvai
Laboratory of Immunology, 3rd Department of Medicine, University of Debrecen Medical and Health Science Center, 98 Nagyerdei Street, Debrecen, H 4012, Hungary
Rheumatology (Oxford) 49:25-33. 2010..Instead of comparing allele-carriers to non-carriers, we studied each allele group individually, using the X/X (non-SE) genotype as reference...
Assessment of subclinical vascular disease associated with ankylosing spondylitisNóra Bodnár
Department of Rheumatology, Institute of Medicine, Hungary
J Rheumatol 38:723-9. 2011..We assessed endothelial dysfunction, carotid atherosclerosis, and aortic stiffness in AS in context with clinical and laboratory measurements...
A comparative study of arterial stiffness, flow-mediated vasodilation of the brachial artery, and the thickness of the carotid artery intima-media in patients with systemic autoimmune diseasesPal Soltesz
Cardiovascular Unit, Institute of Medicine, Third Department of Medicine, University of Debrecen Medical and Health Science Center, Debrecen, 4032, Hungary
Clin Rheumatol 28:655-62. 2009..Assessment of arterial stiffness, FMD, and ccIMT are reproducible and reliable noninvasive techniques for the complex assessment of vascular abnormalities in patients at high risk...
Anti-citrullinated protein antibodies in rheumatoid arthritis: as good as it gets?Zoltan Szekanecz
Division of Rheumatology, 3rd Department of Medicine, Medical and Health Science Center, University of Debrecen, 22 Moricz Street, Debrecen, H 4004, Hungary
Clin Rev Allergy Immunol 34:26-31. 2008..The family of ACPAs is expected to expand; there is an increasing need for developing new diagnostic strategies after careful evaluation of the characteristics of the available assays...
Effects of adalimumab treatment on vascular disease associated with early rheumatoid arthritisGyörgy Kerekes
Cardiovascular Unit, Third Department of Medicine, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
Isr Med Assoc J 13:147-52. 2011..Tumor necrosis factor-alpha (TNFa) inhibitors may influence flow-mediated vasodilation (FMD) of the brachial artery, common carotid intima-media thickness (ccIMT) and arterial stiffness indicated by pulse-wave velocity (PWV) in RA...
Effects of biologics on vascular function and atherosclerosis associated with rheumatoid arthritisGyörgy Kerekes
Cardiovascular Unit, Third Department of Medicine, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
Ann N Y Acad Sci 1173:814-21. 2009..Preliminary data suggest that rituximab may also improve endothelial function and dyslipidemia. Further studies are needed to determine the net effects of biologics on the vasculature...
Combined plasmapheresis and high-dose intravenous immunoglobulin treatment in systemic sclerosis for 12 months: follow-up of immunopathological and clinical effectsZoltan Szekanecz
Department of Rheumatology, University of Debrecen Medical Center, 22 Moricz Street, Debrecen 4004, Hungary
Clin Rheumatol 28:347-50. 2009....
Genetic control of experimental spondylarthropathyZoltan Szabo
University of Debrecen, Hungary
Arthritis Rheum 52:2452-60. 2005..To characterize experimentally induced spondylarthropathy (SpA) in arthritis-susceptible inbred mice and in their F(1) and F(2) hybrid generations of susceptible and resistant mouse strains...
Disturbances in B- and T-cell homeostasis in rheumatoid arthritis: suggested relationships with antigen-driven immune responsesAndrea Fekete
Laboratory of Immunology, 3rd Department of Medicine, Medical and Health Science Center, University of Debrecen, 22 Moricz Street, H 4032 Debrecen, Hungary
J Autoimmun 29:154-63. 2007....
Accelerated atherosclerosis in rheumatoid arthritisZoltan Szekanecz
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
Ann N Y Acad Sci 1108:349-58. 2007....
Association of systemic and thyroid autoimmune diseasesEdit Biro
3rd Department of Medicine, University of Debrecen Medical and Health Sciences Center, 22 Moricz Street, 4004 Debrecen, Hungary
Clin Rheumatol 25:240-5. 2006..In this study, we wished to determine the association of Hashimoto's thyroiditis (HT) and Graves' disease (GD) with systemic autoimmune diseases...
Mechanisms of Disease: angiogenesis in inflammatory diseasesZoltan Szekanecz
Third Department of Medicine, Rheumatology Division, University of Debrecen Medical Center, 22 Moricz Zs Street, Debrecen, H 4012, Hungary
Nat Clin Pract Rheumatol 3:635-43. 2007..Furthermore, angiogenesis might be targeted by several specific approaches that could be therapeutically used to control inflammatory diseases...
Macrophages and their products in rheumatoid arthritisZoltan Szekanecz
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary
Curr Opin Rheumatol 19:289-95. 2007..Macrophages express adhesion molecules, chemokine receptors and other surface antigens. They also secrete a number of chemokines, cytokines, growth factors, proteases and other mediators...
Chemokines in rheumatic diseasesZoltan Szekanecz
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, H 4004, Hungary
Curr Drug Targets 7:91-102. 2006....
Intracytoplasmic cytokine expression and T cell subset distribution in the peripheral blood of patients with ankylosing spondylitisSandor Szanto
Division of Rheumatology, Third Department of Internal Medicine, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary
J Rheumatol 35:2372-5. 2008..To determine the role of inflammatory mediators in the pathogenesis of ankylosing spondylitis (AS), we investigated peripheral blood lymphocyte subsets and their intracellular cytokine production...
Chemokines and angiogenesis in rheumatoid arthritisZoltan Szekanecz
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, H 4004, Hungary
Front Biosci (Elite Ed) 1:44-51. 2009..Apart from discussing the pathogenic role of chemokines and chemokine receptors in arthritic vessel formation, authors also review the important relevance of chemokines and angiogenesis for therapeutic intervention...
Increased arterial stiffness as the marker of vascular involvement in systemic sclerosisOrsolya Timar
Third Department of Medicine, Cardiovascular Unit and Rheumatology Division, University of Debrecen Medical Center, Debrecen, Hungary
J Rheumatol 35:1329-33. 2008..Accelerated atherosclerosis and impaired flow-mediated vasodilation have been described in SSc. We evaluated arterial stiffness in patients with SSc compared to healthy controls...
Anti-mutated citrullinated vimentin (anti-MCV) and anti-65 kDa heat shock protein (anti-hsp65): new biomarkers in ankylosing spondylitisNóra Bodnár
Department of Rheumatology, Institute of Medicine, Medical and Health Science Center, University of Debrecen, 98, Nagyerdei street, 4012 Debrecen, Hungary
Joint Bone Spine 79:63-6. 2012..As new laboratory biomarkers of AS are needed, we investigated the prevalence of anti-mutated citrullinated vimentin (MCV) and anti-hsp65 antibodies in AS...
In vivo calcium and phosphate iontophoresis for the topical treatment of osteoporosisIzabella Gomez
Department of Rheumatology, University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary
Phys Ther 92:289-97. 2012..In addition to systemic treatment, osteoporosis may be treated topically by incorporating calcium and phosphate into the bone...
Angiogenesis and chemokines in rheumatoid arthritis and other systemic inflammatory rheumatic diseasesEdit Bodolay
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, H-4004, Hungary
J Cell Mol Med 6:357-76. 2002....
Chemokines and chemokine receptors in arthritisZoltan Szekanecz
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary, Europe
Front Biosci (Schol Ed) 2:153-67. 2010..However, it is very likely that various specific chemokine and chemokine receptor antagonists will be developed and administered to RA patients...
Chemokines and chemokine receptors in rheumatoid arthritisZoltan Szekanecz
Rheumatology Division, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen H 4004, Hungary
Semin Immunol 15:15-21. 2003..Finally, potential strategies using anti-chemokine or anti-chemokine receptor biologicals in anti-rheumatic therapy are discussed...
Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targetsBertalan Mesko
Department of Biochemistry and Molecular Biology, University of Debrecen, Debrecen, Hungary
BMC Med Genomics 3:15. 2010..The main focus of our work was the identification of novel markers that overlap among the 3 diseases or discriminate them from each other...
Tumor-associated antigens in systemic sclerosis and systemic lupus erythematosus: associations with organ manifestations, immunolaboratory markers and disease activity indicesEva Szekanecz
Department of Oncology, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary
J Autoimmun 31:372-6. 2008..Some of these TAAs contain sialylated carbohydrate motifs and they are involved in tumor-associated cell adhesion and metastasis...
Plasma homocysteine levels, the prevalence of methylenetetrahydrofolate reductase gene C677T polymorphism and macrovascular disorders in systemic sclerosis: risk factors for accelerated macrovascular damage?Szilvia Szamosi
Department of Rheumatology, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary
Clin Rev Allergy Immunol 36:145-9. 2009..Elevated Hcy levels may be associated with disease duration and the evolution of macrovascular disorders and pulmonary hypertension in SSc...
The genetic background of ankylosing spondylitisAniko Vegvari
Department of Rheumatology, Institute of Medicine, University of Debrecen Medical and Health Science Center, 22, Móricz street, Debrecen, H 4032, Hungary
Joint Bone Spine 76:623-8. 2009..Thus, AS is not a single-gene disease and the involvement of multiple non-MHC genes may account for the individual as well as geographical differences seen in AS...
Malignancies associated with systemic sclerosisEva Szekanecz
Department of Oncology, Department of Rheumatology, University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary
Autoimmun Rev 11:852-5. 2012..The adequate treatment and follow-up of scleroderma patients may help us to lower the risk of malignancies secondary to SSc...
Angiogenesis in rheumatoid arthritisZoltan Szekanecz
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, H 4004, Hungary
Front Biosci 10:1739-53. 2005..In addition, further perspectives of anti-angiogenic therapy in arthritis are also discussed. Specific targeting of angiogenesis may be useful in the future management of various inflammatory, as well as malignant, diseases...
Malignancies and soluble tumor antigens in rheumatic diseasesEva Szekanecz
Department of Oncology, University of Debrecen, Medical and Health Science Center, Móricz, Hungary
Autoimmun Rev 6:42-7. 2006..Tumor-associated antigens may be produced by inflammatory cells and their production may be increased in RA and other autoimmune diseases...
Clinical evaluation of anti-mutated citrullinated vimentin by ELISA in rheumatoid arthritisLilla Soos
Division of Rheumatology, Laboratory of Immunology, Department of Medicine, University of Debrecen, Medical and Health Science Center, Hungarian Academy of Sciences, Debrecen, Hungary
J Rheumatol 34:1658-63. 2007..We examined the diagnostic performance of the newly developed anti-mutated citrullinated vimentin (MCV) antibody assay...
Endothelial cells in inflammation and angiogenesisZoltan Szekanecz
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen H 4004, Hungary
Curr Drug Targets Inflamm Allergy 4:319-23. 2005..Specific targeting of pathological endothelial function including adhesion and angiogenesis, may be useful for the future management of various inflammatory diseases...
Therapeutic inhibition of leukocyte recruitment in inflammatory diseasesZoltan Szekanecz
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, H 4004, Hungary
Curr Opin Pharmacol 4:423-8. 2004..In this review, the most recent advances in anti-chemokine and anti-adhesion therapeutic strategies are summarized...
Incidence of lymphoma in systemic sclerosis: a retrospective analysis of 218 Hungarian patients with systemic sclerosisEva Szekanecz
Department of Oncology, University of Debrecen Medical Center, Debrecen, Hungary
Clin Rheumatol 27:1163-6. 2008..In our three patients, B cell lymphoma developed within 2 years after the onset of SSc. Altered B cell function implicated in the pathogenesis of SSc may lead to the development of lymphoid malignancies...
Non-MHC risk alleles in rheumatoid arthritis and in the syntenic chromosome regions of corresponding animal modelsTimea Besenyei
Department of Rheumatology, Faculty of Medicine, Medical and Health Science Centre, University of Debrecen, Debrecen 4012, Hungary
Clin Dev Immunol 2012:284751. 2012..Mouse GWAS appear to be far ahead of rat studies, and significantly more mouse QTLs correspond to human RA risk alleles...
Expression of bone morphogenetic protein 2, 4, 5, and 7 correlates with histological activity of otosclerotic fociPéter Csomor
Department of Otolaryngology and Head and Neck Surgery, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
Acta Otolaryngol 132:624-31. 2012..These results confirm that elevated expression levels of BMPs, members of the transforming growth factor (TGF)-β superfamily, contribute to the pathologically increased bone turnover in early, active stages of otosclerosis...
Validated methods for assessment of subclinical atherosclerosis in rheumatologyGyörgy Kerekes
Angiology and Intensive Care Unit, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, 98 Nagyerdei Street, Debrecen H 4032, Hungary
Nat Rev Rheumatol 8:224-34. 2012..The potential use of a multimarker approach to increase the diagnostic and prognostic value of these clinical assessments is also discussed...
Capsular neuronal elements and their relation to pain reduction and functional improvement following total hip replacementLevente Gáspár
Department of Orthopaedic Surgery, Medical Health and Science Center, University of Debrecen, Nagyerdei krt 98, 4012, Debrecen, Hungary
Int Orthop 28:142-5. 2004..Thus, other factors than capsular neurofilaments influence the scores of pain and disability in osteoarthritis...
Increased production of asymmetric dimethylarginine (ADMA) in ankylosing spondylitis: association with other clinical and laboratory parametersAdam Kemeny-Beke
Department of Ophthalmology, University of Debrecen, Medical and Health Science Center, Debrecen 4032, Hungary
Joint Bone Spine 78:184-7. 2011..Asymmetric dimethylarginine (ADMA) has been associated with atherosclerosis, vascular diseases and, recently, also with arthritis including rheumatoid arthritis (RA) and ankylosing spondylitis (AS)...
Association of HELLP syndrome with primary antiphospholipid syndrome--a case reportKatalin Veres
Cardiovascular Unit, 3rd Department of Internal Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
Clin Rheumatol 27:111-3. 2008..There have been only few scattered reports in the literature on the association of HELLP syndrome and APS, which was successfully managed with the combination of various immunosuppressive and immunomodulatory treatment modalities...
Vascular involvement in rheumatic diseases: 'vascular rheumatology'Zoltan Szekanecz
University of Debrecen Medical Center, Institute of Medicine, Department of Rheumatology, 22 Moricz Street, Debrecen, H 4032, Hungary
Arthritis Res Ther 10:224. 2008..Vasoprotective agents may help to prevent premature atherosclerosis and cardiovascular disease...
Angiogenesis and its targeting in rheumatoid arthritisZoltan Szekanecz
Department of Rheumatology, Institute of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, H 4012 Hungary
Vascul Pharmacol 51:1-7. 2009..Potentially any angiostatic compound could be introduced to studies using animal models of arthritis or even to human rheumatoid arthritis trials...
Catastrophic antiphospholipid syndrome (Asherson's syndrome) associated with cytokeratin 7-positive endometrial cancerPal Soltesz
Cardiovascular Unit, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
Isr Med Assoc J 9:891-3. 2007
Evaluation of tear osmolarity in non-Sjögren and Sjögren syndrome dry eye patients with the TearLab systemEszter Szalai
Department of Ophthalmology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
Cornea 31:867-71. 2012....
Association of ANCA-associated vasculitis-rheumatoid arthritis overlap syndrome in four patients: rituximab may be the right choice?Maria Szilasi
Department of Pulmonology, University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary
Autoimmunity 45:304-9. 2012..There have been few reports on the association of rheumatoid arthritis (RA) with anti-neutrophil cytoplasmic antigen (ANCA)-associated systemic vasculitides...
Meningitis in mixed connective tissue disease complicated by herpes virus infection: case reportEdit Bodolay
Division of Clinical Immunology, Third Department of Internal Medicine, University of Debrecen Medical and Health Science Center, 4004 Debrecen, Moricz Zs 22, Hungary
Rheumatol Int 24:359-61. 2004..The administration of corticosteroids resulted in rapid improvements in clinical symptoms and laboratory indicators...
Balneotherapy in elderly patients: effect on pain from degenerative knee and spine conditions and on quality of lifeJanos Gaal
Department of Rheumatology, Kenézy Gyula County Hospital, Debrecen, Hungary
Isr Med Assoc J 10:365-9. 2008..Balneotherapy is an established treatment modality for musculoskeletal disease, but few studies have examined the efficacy of spa therapy in elderly patients with degenerative spine and joint diseases...
Otosclerosis: an autoimmune disease?Tamás Karosi
Department of Otolaryngology and Head and Neck Surgery, University of Debrecen Medical and Health Science Center, Debrecen, Hungary
Autoimmun Rev 9:95-101. 2009....
Cardiac manifestations in antiphospholipid syndromePal Soltesz
Third Department of Medicine, Cardiovascular Unit, University Medical School of Debrecen, Debrecen, H 4004, Hungary
Autoimmun Rev 6:379-86. 2007....
Improvement in pain intensity, spine stiffness, and mobility during a controlled individualized physiotherapy program in ankylosing spondylitisZsuzsanna Némethné Gyurcsik
Department of Physiotherapy, Faculty of Public Health, Medical and Health Sciences Center, University of Debrecen, Kassai u 26, 4028 Debrecen, Hungary
Rheumatol Int 32:3931-6. 2012..A complex, individualized physical therapy program may be useful and should be introduced to AS patients in order to maintain and increase spine mobility, preserve functional capacity, decrease the pain and stiffness...
Vascular endothelium and immune responses: implications for inflammation and angiogenesisZoltan Szekanecz
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, 22 Moricz Street, Debrecen H 4004, Hungary
Rheum Dis Clin North Am 30:97-114. 2004..Specific targeting of pathologic endothelial function may be useful for the future management of various inflammatory diseases...
Technique of synovial biopsy of metacarpophalangeal joints using the needle arthroscopeLevente Gáspár
Department of Orthopedics, Medical Health and Science CenterUniversity of Debrecen, Nagyerdei krt 98, 4012, Debrecen, Hungary
Knee Surg Sports Traumatol Arthrosc 11:50-2. 2003..The tight tension of the joint and traction of the finger is necessary for good visualization, but despite this visibility can be difficult. Needle biopsy is a useful method for the early diagnosis of rheumatoid arthritis...
Vitamin D receptor gene polymorphism in rheumatoid arthritis and associated osteoporosisPéter Rass
Division of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Science Center, 22 Moricz Street, 4004 Debrecen, Hungary
Rheumatol Int 26:964-71. 2006..The possible involvement of vitamin D and VDR gene polymorphisms in the development and progression of RA needs further elucidation...
Coexistence of ankylosing spondylitis and rheumatoid arthritis in a female patientBeáta Baksay
Department of Rheumatology, Hospital of Hungarian State Railways, Verseghy str 6 8, Szolnok, Hungary
Clin Rheumatol 30:1119-22. 2011..In 2007, authors diagnosed seropositive RA. Therapy included anti-inflammatory therapy and traditional disease-modifying agents, eventually followed by biological therapy...
Serum cytokine levels and type 1 and type 2 intracellular T cell cytokine profiles in mixed connective tissue diseaseEdit Bodolay
3rd Department of Internal Medicine, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary
J Rheumatol 29:2136-42. 2002..To determine serum cytokine concentrations and intracellular cytokine production of CD4+ and CD8+ T cells in 20 patients with mixed connective tissue disease (MCTD)...
Development of natural calcium- and phosphate-donating microparticles and a new iontophoretic apparatus for the topical treatment of local osteoporosis. Preliminary in vitro and in vivo studiesLajos Pap
University of Debrecen, Department of Inorganic and Analytical Chemistry, Debrecen, Hungary
Joint Bone Spine 77:426-31. 2010..We wished to develop a new iontophoretic device suitable for the treatment of local bone loss such as after fractures or in osteodystrophy...
