Janos Kappelmayer

Summary

Affiliation: University of Debrecen
Country: Hungary

Publications

  1. ncbi request reprint Monocytes express tissue factor in young patients with cerebral ischemia
    J Kappelmayer
    Department of Clinical Chemistry, University Medical School, Debrecen, Hungary
    Cerebrovasc Dis 8:235-9. 1998
  2. ncbi request reprint Flow cytometric detection of intracellular myeloperoxidase, CD3 and CD79a. Interaction between monoclonal antibody clones, fluorochromes and sample preparation protocols
    J Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, University Medical School of Debrecen, P O Box 40, Nagyerdei krt 98, H 4012 Debrecen, Hungary
    J Immunol Methods 242:53-65. 2000
  3. ncbi request reprint Identification of P-selectin glycoprotein ligand-1 as a useful marker in acute myeloid leukaemias
    J Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Sciences Centre, University of Debrecen, PO Box 40, Debrecen, Hungary H 4012
    Br J Haematol 115:903-9. 2001
  4. ncbi request reprint "Pros and cons" on how to measure multidrug resistance in leukemias
    Janos Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, Budapest, Hungary
    Leuk Lymphoma 43:711-7. 2002
  5. ncbi request reprint Progesterone administration fails to protect albino male rats against photostress-induced retinal degeneration
    I Kaldi
    Department of Ophthalmology, Kenezy Hospital, Debrecen, Hungary
    Eur J Ophthalmol 14:306-14. 2004
  6. ncbi request reprint The emerging value of P-selectin as a disease marker
    Janos Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Clin Chem Lab Med 42:475-86. 2004
  7. ncbi request reprint Progress in defining multidrug resistance in leukemia
    Janos Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary H 4032
    Expert Rev Mol Diagn 4:209-17. 2004
  8. doi request reprint Expression of coagulation factor XIII subunit A in acute promyelocytic leukemia
    Agnes Simon
    Department of Laboratory Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Cytometry B Clin Cytom 82:209-16. 2012
  9. ncbi request reprint Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies
    Henrietta Nagy
    Department of Biophysics and Cell Biology, University of Debrecen, Debrecen, Hungary
    Biochem Biophys Res Commun 315:942-9. 2004
  10. doi request reprint Binding of plasma factor XIII to thrombin-receptor activated human platelets
    Bela Nagy
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Thromb Haemost 102:83-9. 2009

Collaborators

Detail Information

Publications55

  1. ncbi request reprint Monocytes express tissue factor in young patients with cerebral ischemia
    J Kappelmayer
    Department of Clinical Chemistry, University Medical School, Debrecen, Hungary
    Cerebrovasc Dis 8:235-9. 1998
    ..05). In conclusion, in cerebral ischemia TF expression on monocytes suggests enhanced activation of blood coagulation and subsequent fibrinolysis...
  2. ncbi request reprint Flow cytometric detection of intracellular myeloperoxidase, CD3 and CD79a. Interaction between monoclonal antibody clones, fluorochromes and sample preparation protocols
    J Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, University Medical School of Debrecen, P O Box 40, Nagyerdei krt 98, H 4012 Debrecen, Hungary
    J Immunol Methods 242:53-65. 2000
    ..Thus, combined selection of fixation/permeabilization kits and monoclonal antibody reagents against CD3, CD79a and MPO is required for obtaining optimal cytoplasmic detection of these antigens...
  3. ncbi request reprint Identification of P-selectin glycoprotein ligand-1 as a useful marker in acute myeloid leukaemias
    J Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Sciences Centre, University of Debrecen, PO Box 40, Debrecen, Hungary H 4012
    Br J Haematol 115:903-9. 2001
    ....
  4. ncbi request reprint "Pros and cons" on how to measure multidrug resistance in leukemias
    Janos Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, Budapest, Hungary
    Leuk Lymphoma 43:711-7. 2002
    ..Thus, we believe that functional assays when carried out in a standardized way and particularly combined with labeling for various surface markers can be recommended as a front-line test in MDR measurement...
  5. ncbi request reprint Progesterone administration fails to protect albino male rats against photostress-induced retinal degeneration
    I Kaldi
    Department of Ophthalmology, Kenezy Hospital, Debrecen, Hungary
    Eur J Ophthalmol 14:306-14. 2004
    ..The aim of this study was to test the protective effect of female sexual hormones against photostress-induced photoreceptor apoptosis...
  6. ncbi request reprint The emerging value of P-selectin as a disease marker
    Janos Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Clin Chem Lab Med 42:475-86. 2004
    ..Such results bear clinical significance since P-selectin has been implicated in the pathogenesis of wide-spread disorders including coronary artery disease, stroke, diabetes and malignancy...
  7. ncbi request reprint Progress in defining multidrug resistance in leukemia
    Janos Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary H 4032
    Expert Rev Mol Diagn 4:209-17. 2004
    ..The authors believe that a standardized MDR assay, as well as a suitable monitoring test, may become a prognostic marker in several types of leukemia...
  8. doi request reprint Expression of coagulation factor XIII subunit A in acute promyelocytic leukemia
    Agnes Simon
    Department of Laboratory Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Cytometry B Clin Cytom 82:209-16. 2012
    ..This novel expression site of FXIII-A in AML M3 can be considered as a leukemia associated immunophenotype and may have pathophysiological significance...
  9. ncbi request reprint Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies
    Henrietta Nagy
    Department of Biophysics and Cell Biology, University of Debrecen, Debrecen, Hungary
    Biochem Biophys Res Commun 315:942-9. 2004
    ..The rest of the drugs either did not affect antibody competition or had a modest effect. Thus, Pgp substrates/modulators can be classified into distinct modalities based on the conformational change they elicit...
  10. doi request reprint Binding of plasma factor XIII to thrombin-receptor activated human platelets
    Bela Nagy
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Thromb Haemost 102:83-9. 2009
    ..We conclude that FXIII-A(2)B(2) of plasma origin binds to thrombin-receptor activated platelets via GPIIb/IIIa receptor-bound fibrinogen with gamma'-chain and is not capable of direct platelet binding...
  11. doi request reprint Direct thrombin inhibitors and factor xa inhibitors can influence the diluted prothrombin time used as the initial screen for lupus anticoagulant
    Zsolt Oláh
    2nd Department of Medicine, University of Debrecen, 4032 Debrecen, Hungary
    Arch Pathol Lab Med 137:967-73. 2013
    ..The effect of different types of anticoagulants on the result of LA tests, particularly on dPT, has not been studied extensively...
  12. ncbi request reprint A coagulation factor becomes useful in the study of acute leukemias: studies with blood coagulation factor XIII
    Flora Kiss
    Department of Clinical Biochemistry and Molecular Pathology, University of Debrecen, Hungary
    Cytometry A 73:194-201. 2008
    ..These data provide evidence that FXIII-A is a sufficiently sensitive marker in differentiating myeloblasts and monoblasts and is suitable for identifying leukemia-associated phenotypes in ALL...
  13. ncbi request reprint Three novel mutations in the glycoprotein IIb gene in a patient with type II Glanzmann thrombasthenia
    Gergely Losonczy
    Clinical Research Center, Thrombosis and Hemostasis Research Group of the Hungarian Academy of Sciences, University of Debrecen, Debrecen, Hungary
    Haematologica 92:698-701. 2007
    ..The p.His782Asn mutation compromised transport of the pro-GPIIb/IIIa complex from the endoplasmic reticulum to the Golgi, hindering its maturation and surface expression...
  14. doi request reprint Alfacalcidol treatment restores derailed immune-regulation in patients with undifferentiated connective tissue disease
    Eva Zold
    Division of Clinical Immunology, 3rd Department of Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Autoimmun Rev 10:155-62. 2011
    ....
  15. ncbi request reprint Biological microbeads for flow-cytometric immunoassays, enzyme titrations, and quantitative PCR
    Judit Pataki
    Department of Biophysics and Cell Biology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Cytometry A 68:45-52. 2005
    ..Development of this field has lead to specialized instrumentation and microbead arrays, dedicated to certain applications...
  16. ncbi request reprint Mean fluorescence intensity rate is a useful marker in the detection of paroxysmal nocturnal hemoglobinuria clones
    Zsuzsa Hevessy
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Nagyerdei krt 98, Debrecen, Hungary
    Clin Chem Lab Med 43:919-23. 2005
    ..021-0.34). Thus, CD14 on monocytes seems to be the most reliable marker for establishing the PNH clone size and the severity of antigen deficiency...
  17. ncbi request reprint Effects of ad hoc clopidogrel loading versus pre-treatment on P-selectin expression after coronary stent implantation
    Tibor Szuk
    Institute of Cardiology, Debrecen, Hungary
    Platelets 17:344-6. 2006
    ..Aspirin non-responsiveness did not influence the results. These data point to the beneficial effect of clopidogrel treatment in reducing platelet reactivity during stenting...
  18. doi request reprint Laboratory evaluation of a flow cytometric BCR-ABL immunobead assay
    Zsuzsanna Hevessy
    Department of Laboratory Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Clin Chem Lab Med 50:689-92. 2012
    ..A new flow cytometric (FC) BCR-ABL immunobead assay has been developed recently. Here we present the laboratory evaluation of the commercially available kit...
  19. doi request reprint Increased levels of platelet activation markers are positively associated with carotid wall thickness and other atherosclerotic risk factors in obese patients
    Eva Csongradi
    1st Department of Medicine, Medical and Health Science Center, University of Debrecen, Hungary
    Thromb Haemost 106:683-92. 2011
    ..009). In conclusion, P-selectin and PMP levels showed positive associations with abnormal carotid IMT and other risk factors in obesity suggesting a critical role of enhanced platelet reactivity in atherosclerotic wall alteration...
  20. ncbi request reprint Anthracycline antibiotics induce acute renal tubular toxicity in children with cancer
    Edit Bardi
    Department of Pediatrics, Medical and Health Science Center, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Pathol Oncol Res 13:249-53. 2007
    ..The damage was clinically mild and only a minor proportion of patients can be expected to develop long-lasting tubulopathy with negative impact on the quality of life...
  21. ncbi request reprint Late effects on renal glomerular and tubular function in childhood cancer survivors
    Edit Bardi
    Department of Pediatrics, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Pediatr Blood Cancer 43:668-73. 2004
    ..Late nephrotoxicity among childhood cancer survivors is poorly documented...
  22. doi request reprint Detection of mutations by flow cytometric melting point analysis of PCR products
    Laszlo Imre
    Department of Biophysics and Cell Biology, Medical and Health Science Center, University of Debrecen, Hungary
    Cytometry A 79:720-6. 2011
    ..In general, the method described herein is offered for the diagnosis of any pathological condition where the length of a genomic or cDNA sequence is expected to be different from that of the normal allele...
  23. doi request reprint Lack of P-selectin glycoprotein ligand-1 protects mice from thrombosis after collagen/epinephrine challenge
    Kornél Miszti-Blasius
    Department of Clinical Biochemistry and Molecular Pathology, Hungary
    Thromb Res 127:228-34. 2011
    ..Our aim was to establish the role of PSGL-1 in thrombus formation by evaluating the response to thrombotic stimuli in wild type and PSGL-1 knockout mice...
  24. ncbi request reprint Variant translocations of 11q23 in infant acute lymphoblastic leukemia (ALL): do outcomes differ from t(4;11)?
    Zsuzsanna Jakab
    Department of Pediatrics, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Med Pediatr Oncol 39:63-5. 2002
  25. doi request reprint Rapid-onset heparin-induced thrombocytopenia without previous heparin exposure
    Zsolt Oláh
    2nd Department of Medicine, University of Debrecen, Debrecen, Hungary
    Platelets 23:495-8. 2012
    ..Furthermore, transient presence of anti-phospholipid antibodies can cause a differential diagnostic problem in the cases of HIT...
  26. doi request reprint Monitoring of mycophenolic acid and kidney function during combined immunosuppressive therapy
    Anna V Olah
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Clin Chem Lab Med 49:1849-53. 2011
    ..Still, there is no consensus considering the recommended dosing and the therapeutic range of MPA...
  27. doi request reprint Platelet-derived microparticle levels are significantly elevated in patients treated by elective stenting compared to subjects with diagnostic catheterization alone
    Bela Nagy
    Department of Clinical Biochemistry and Molecular Pathology, University of Debrecen, Hungary
    Platelets 21:147-51. 2010
    ..We suggest that the observed cellular changes are early and sensitive markers to detect the platelet-activating effect of stent implantation...
  28. doi request reprint Protein phosphatase inhibitor calyculin-A modulates activation markers in TRAP-stimulated human platelets
    Zsuzsa Simon
    Department of Clinical Biochemistry and Molecular Pathology, Hungarian Academy of Sciences, Research Center for Molecular Medicine, Medical and Health Science Center, University of Debrecen, Hungary
    Platelets 21:555-62. 2010
    ..In conclusion, PP1 and PP2A-catalyzed dephosphorylation processes have crucial roles in PMP formation and in the regulation of alpha-granule and lysosome secretion in human platelets...
  29. doi request reprint Classical and atypical neuroblastoma--case reports
    Laszlo Csathy
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Hungary
    Cytometry B Clin Cytom 80:134-6. 2011
    ..In most cases the primary tumor can be identified, but in this particular case only bone marrow involvement could be detected using flow cytometry, as such making it a powerful tool for diagnosis and disease monitoring...
  30. ncbi request reprint Coagulation factor XIII-A. A flow cytometric intracellular marker in the classification of acute myeloid leukemias
    Janos Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Centre, University of Debrecen, Hungary
    Thromb Haemost 94:454-9. 2005
    ..FXIII-A can be considered as a reliable intracytoplasmic marker for the monocytic and megakaryocytic series and its presence is highly predictive for mono- and megakaryocytic AML and for CMML...
  31. doi request reprint P-selectin glycoprotein ligand-1 deficiency augments G-CSF induced myeloid cell mobilization
    Kornél Miszti-Blasius
    Department of Laboratory Medicine, Medical and Health Science Center, University of Debrecen, Nagyerdei krt 98, 4032, Debrecen, Hungary
    Naunyn Schmiedebergs Arch Pharmacol 387:109-18. 2014
    ....
  32. doi request reprint Acute phase proteins in the diagnosis and prediction of cirrhosis associated bacterial infections
    Maria Papp
    2nd Department of Medicine, Division of Gastroenterology, University of Debrecen, Debrecen, Hungary
    Liver Int 32:603-11. 2012
    ..Bacterial infections are common cause of morbidity and mortality in patients with cirrhosis. The early diagnosis of these infections is rather difficult...
  33. doi request reprint The immunoregulatory role of vitamins A, D and E in patients with primary Sjogren's syndrome
    Peter Szodoray
    3rd Department of Medicine, Division of Clinical Immunology, Medical and Health Science Centre, University of Debrecen, Moricz Zs Str 22, 4032 Debrecen, Hungary
    Rheumatology (Oxford) 49:211-7. 2010
    ..The aim of the present study was to investigate the immunomodulating role of fat-soluble vitamins in 25 patients with primary SS (pSS) and 15 healthy individuals...
  34. ncbi request reprint Investigation of Thr715Pro P-selectin gene polymorphism and soluble P-selectin levels in type 2 diabetes mellitus
    Bela Nagy
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Nagyerdei krt 98, 4032 Hungary
    Thromb Haemost 98:186-91. 2007
    ..We suggest that in type 2 DM individuals, the significantly elevated sP-selectin levels are not due to the Thr715Pro P-selectin gene polymorphism...
  35. ncbi request reprint Early relapse after rituximab chemoimmunotherapy
    Flora Kiss
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Sicence Center, University of Debrecen, Debrecen, Hungary
    Pediatr Blood Cancer 50:372-5. 2008
    ..Rituximab eliminated the CD20-positive subpopulation, but not the more immature leukemic cells. The patient died with fulminant aspergillosis before hematopoietic stem cell transplantation could be performed...
  36. ncbi request reprint Pgp and FLT3: identification and modulation of two proteins that lead to chemotherapy resistance in acute myeloid leukemia
    Janos Kappelmayer
    Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science Center, University of Debrecen, Hungary
    Curr Med Chem 14:519-30. 2007
    ..This review focuses on the pathophysiological phenomena and the detection methods of Pgp and FLT3 as well as on novel therapeutic strategies that are offered by their inhibition...
  37. ncbi request reprint Early-onset carotid atherosclerosis is associated with increased intima-media thickness and elevated serum levels of inflammatory markers
    Maria T Magyar
    Department of Neurology, University of Debrecen, Health Science and Medical Center, Debrecen, Hungary
    Stroke 34:58-63. 2003
    ..Several factors have been held responsible for the development of atherosclerosis. To avoid the masking effect of age, we evaluated correlates of carotid atherosclerosis in patients <55 years of age...
  38. doi request reprint High prevalence of IgA class anti-neutrophil cytoplasmic antibodies (ANCA) is associated with increased risk of bacterial infection in patients with cirrhosis
    Maria Papp
    2nd Department of Medicine, Division of Gastroenterology, University of Debrecen, Debrecen, Hungary
    J Hepatol 59:457-66. 2013
    ..Bacterial infections are common complications in cirrhosis with high incidence of episodes caused by enteric organisms, therefore, we sought to study the presence and clinical importance of ANCA in cirrhosis...
  39. doi request reprint Comparison of coated-platelet levels in patients with essential thrombocythemia with and without hydroxyurea treatment
    Gyula Remenyi
    Department of Hematology, Institute of Internal Medicine, University of Debrecen, Debrecen, Hungary
    Platelets 24:486-92. 2013
    ..0008) increased by hydroxyurea treatment. We suppose that abnormal coated-platelet level may also contribute to platelet dysfunction in ET. ..
  40. doi request reprint Detection of internal tandem duplications in the FLT3 gene by different electrophoretic methods
    Tamás Bubán
    Institute of Internal Medicine, 1st Department of Internal Medicine, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary
    Clin Chem Lab Med 50:301-10. 2012
    ..In acute myeloid leukemia (AML), the internal tandem duplication (ITD) in the juxtamembrane domain of the FLT3 (Fms-like tyrosine kinase 3) gene is one of the most frequent genetic alterations associated with poor prognosis...
  41. doi request reprint Differential effect of corticosteroids on serum cystatin C in thrombocytopenic purpura and leukemia
    Edit Bardi
    Departments of Pediatric Hematology and Oncology, University of Debrecen, Debrecen, Hungary
    Pathol Oncol Res 16:453-6. 2010
    ..04). Although the concentration of cysC may be slightly and reversibly influenced by corticosteroid treatment, cysC is sensitive to detect early and moderate deterioration of GFR in children with cancer...
  42. doi request reprint Stem cell therapy: a promising and prospective approach in the treatment of patients with severe Buerger's disease
    Zoltan Boda
    2nd Department of Medicine, University of Debrecen, Debrecen, Hungary
    Clin Appl Thromb Hemost 15:552-60. 2009
    ..Severe adverse events were not observed. We conclude that ABMSCT with isolated CD34+ cells is safe, effective, and results in sustained clinical benefit for patients with SPAD...
  43. doi request reprint [Autologous bone marrow-derived stem cell therapy in patients with severe peripheral arterial disorder]
    Zoltan Boda
    Debreceni Egyetem, Orvos és Egészségtudományi Centrum, Altalános Orvostudományi Kar II Belgyógyászati Klinika, Haemostasis Tanszék Debrecen Nagyerdei krt 98 4012
    Orv Hetil 149:531-40. 2008
    ..Autologous bone marrow-derived stem cell transplantation is an arising therapy modality with an option of building new blood vessels through endothelial stem and/or progenitor cells...
  44. ncbi request reprint [Activity of natural coagulation inhibitor proteins in the acute phase of ischaemic stroke]
    Laszlo Olah
    Debreceni Egyetem, Orvos és Egészségtudományi Centrum, Neurológiai Klinika, Debrecen
    Ideggyogy Sz 58:33-9. 2005
    ..The authors' aim was to investigate whether the decreased activity of natural anticoagulants is accompanied by worsening of symptoms in ischaemic stroke...
  45. pmc Comparison of a new P2Y12 receptor specific platelet aggregation test with other laboratory methods in stroke patients on clopidogrel monotherapy
    Zsuzsa Bagoly
    Clinical Research Center, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary
    PLoS ONE 8:e69417. 2013
    ..ADP induced platelet aggregation, a widely used test to monitor clopidogrel therapy, is affected by aspirin and is not specific for the P2Y12 receptor inhibited by clopidogrel...
  46. doi request reprint Elevated human epididymis protein 4 concentrations in chronic kidney disease
    Bela Nagy
    Department of Laboratory Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Ann Clin Biochem 49:377-80. 2012
    ..However, it is unknown if the levels of HE4 and CA125 may be altered in subjects who have impaired renal function with no ovarian disorders...
  47. doi request reprint Distribution of CFTR mutations in Eastern Hungarians: relevance to genetic testing and to the introduction of newborn screening for cystic fibrosis
    Gergely Ivády
    Department of Clinical Biochemistry and Molecular Pathology, University of Debrecen, Hungary
    J Cyst Fibros 10:217-20. 2011
    ..Due to the homogeneity of the Hungarian population our data are generally applicable to other regions of the country, including the sizeable diaspora...
  48. doi request reprint Increased platelet glycoprotein Ib receptor number, enhanced platelet adhesion and severe cerebral ischaemia in a patient with polycythaemia vera
    Judit Toth
    Clinical Research Center, University of Debrecen, Debrecen, Hungary
    Platelets 20:282-7. 2009
    ..Similar results with pathological findings have not been published in PV until now. Our result undersigns the necessity of antiplatelet therapy of PV patients, even at normal platelet count...
  49. ncbi request reprint A novel homozygous mutation (1619delC) in GPIIb gene associated with Glanzmann thrombasthenia, the decay of GPIIb-mRNA and the synthesis of a truncated GPIIb unable to form complex with GPIIIa
    Gergely Losonczy
    Clinical Research Center, University of Debrecen, Medical and Health Science Center, Hungary
    Thromb Haemost 93:904-9. 2005
    ....
  50. ncbi request reprint ["Turnaround time": a new parameter for the characterization of the overall efficacy of laboratory diagnostic processes]
    Peter Antal-Szalmas
    Debreceni Egyetem Orvos és Egészségtudományi Centrum, Klinikai Biokémiai és Molekuláris Patológiai Intézet, Debrecen, Hungary
    Orv Hetil 148:1317-27. 2007
    ..It characterizes the efficacy of the result generation process very well, and therefore, is considered as an important parameter of laboratory quality control...
  51. doi request reprint Increased mean platelet volume in primary Raynaud's phenomenon
    Amir Houshang Shemirani
    Clinical Research Center, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Platelets 23:312-6. 2012
    ..3, 95% CI: 4.85-26.12, p<0.001) were found to be independently associated with PRP. In conclusion, increased MPV is independently related to PRP, and its level was not influenced by age, gender, and the duration of PRP...
  52. ncbi request reprint Cystatin C is a suitable marker of glomerular function in children with cancer
    Edit Bardi
    Department of Pediatrics, Medical and Health Science Center, University of Debrecen, Hungary
    Pediatr Nephrol 19:1145-7. 2004
    ..CysC increased significantly after cisplatin, methotrexate, cyclophosphamide, ifosfamide, and multimodality treatment. Our results suggest that cysC measurement can be used to characterize glomerular function in children with cancer...
  53. doi request reprint Synthesis and anticoagulant activity of bioisosteric sulfonic-Acid analogues of the antithrombin-binding pentasaccharide domain of heparin
    Mihály Herczeg
    Research Group for Carbohydrates of the Hungarian Academy of Sciences, University of Debrecen, 4010, Debrecen, P O Box 94, Hungary
    Chemistry 18:10643-52. 2012
    ..The difference in the biological activity of the disulfonic- and trisulfonic-acid counterparts could be explained by the different conformation of their L-iduronic-acid residues...
  54. pmc Vitamin D deficiency in undifferentiated connective tissue disease
    Eva Zold
    Division of Clinical Immunology, 3rd Department of Medicine, Medical and Health Science Center, University of Debrecen, Moricz Zs, Str, 22, Debrecen, 4032, Hungary
    Arthritis Res Ther 10:R123. 2008
    ..The aim of the present study was to investigate the prevalence of vitamin D insufficiency in patients with undifferentiated connective tissue disease (UCTD)...
  55. ncbi request reprint Long-lasting partial remission by Interferon-alpha treatment in a child with essential thrombocythemia
    Istvan Szegedi
    Department of Pediatrics, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    Pediatr Blood Cancer 49:744-7. 2007
    ..After 65 months of in vivo IFN treatment, the patient experienced a sustained partial remission with platelet counts varying between 400 and 600 x 10(3)/microl...