Affiliation: University of Szeged
Domoki F, Zimmermann A, Cserni G, Bori R, Temesvari P, Bari F. Reventilation with room air or 100% oxygen after asphyxia differentially affects cerebral neuropathology in newborn pigs. Acta Paediatr. 2006;95:1109-15 pubmed
..O2 toxicity after asphyxia was demonstrated in the piglet hippocampus and cerebellum but not in the cerebral cortex or basal ganglia. The observed regional differences may be associated with local haemodynamic factors. ..
Domoki F, Kis B, Gaspar T, Snipes J, Parks J, Bari F, et al
. Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivation in cultured cortical neurons. Am J Physiol Cell Physiol. 2009;296:C97-105 pubmed publisher
..Reduced neuronal ATP levels and ROS production after OGD may be directly involved in the mechanism of neuroprotection. ..
Domoki F, Perciaccante J, Shimizu K, Puskar M, Busija D, Bari F. N-methyl-D-aspartate-induced vasodilation is mediated by endothelium-independent nitric oxide release in piglets. Am J Physiol Heart Circ Physiol. 2002;282:H1404-9 pubmed
..In conclusion, NMDA appears to dilate pial arterioles exclusively through release and diffusion of NO from neurons to the pial surface in piglets. ..
Domoki F, Nagy K, Temesvari P, Bari F. Selective inhibitors differentially affect cyclooxygenase-dependent pial arteriolar responses in newborn pigs. Pediatr Res. 2005;57:853-7 pubmed
..We conclude that the assessed COX-dependent vascular reactions appear to depend largely on COX-2 activity. However, hypercapnia-induced vasodilation was found indomethacin-sensitive instead of a COX-dependent response in the piglet. ..
Domoki F, Zölei D, Oláh O, Toth Szuki V, Hopp B, Bari F, et al
. Evaluation of laser-speckle contrast image analysis techniques in the cortical microcirculation of piglets. Microvasc Res. 2012;83:311-7 pubmed publisher
..In summary, LASCA emerges as an appealing method to simultaneously study microvascular reactivity and cortical perfusion changes in the piglet. ..