T Biro

Summary

Affiliation: University of Debrecen
Country: Hungary

Publications

  1. ncbi request reprint How best to fight that nasty itch - from new insights into the neuroimmunological, neuroendocrine, and neurophysiological bases of pruritus to novel therapeutic approaches
    T Biro
    Department of Physiology, University of Debrecen, Medical and Health Sciences Center, H 4012 Debrecen, PO Box 22, Hungary
    Exp Dermatol 14:225-40. 2005
  2. doi request reprint Transient receptor potential vanilloid-1 signaling inhibits differentiation and activation of human dendritic cells
    Balazs I Toth
    Department of Physiology, University of Debrecen, Medical and Health Science Center, Research Center for Molecular Medicine, 4032 Debrecen, Nagyerdei krt 98, P O Box 22, Hungary
    FEBS Lett 583:1619-24. 2009
  3. doi request reprint An "ice-cold" TR(i)P to skin biology: the role of TRPA1 in human epidermal keratinocytes
    Tamas Biro
    Department of Physiology, University of Debrecen, Research Center for Molecular Medicine, Debrecen, Hungary
    J Invest Dermatol 129:2096-9. 2009
  4. pmc The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities
    Tamas Biro
    Department of Physiology, University of Debrecen, Research Center for Molecular Medicine, Debrecen 4032, Hungary
    Trends Pharmacol Sci 30:411-20. 2009
  5. ncbi request reprint TRP channels as novel players in the pathogenesis and therapy of itch
    Tamas Biro
    Department of Physiology, University of Debrecen, Medical and Health Science Center, Research Center for Molecular Medicine, 4032 Debrecen, Hungary
    Biochim Biophys Acta 1772:1004-21. 2007
  6. ncbi request reprint Differential distribution of TASK-1, TASK-2 and TASK-3 immunoreactivities in the rat and human cerebellum
    Z Rusznák
    Department of Physiology, Medical and Health Science Centre, University of Debrecen, 4012 Debrecen, Hungary
    Cell Mol Life Sci 61:1532-42. 2004
  7. doi request reprint Protein kinase C isoenzymes differentially regulate the differentiation-dependent expression of adhesion molecules in human epidermal keratinocytes
    Andrea Szegedi
    Department of Dermatology, University of Debrecen, Debrecen, Hungary
    Exp Dermatol 18:122-9. 2009
  8. doi request reprint Investigation of micronized titanium dioxide penetration in human skin xenografts and its effect on cellular functions of human skin-derived cells
    Borbala Kiss
    Department of Dermatology, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary
    Exp Dermatol 17:659-67. 2008
  9. doi request reprint Altered calcium handling following the recombinant overexpression of protein kinase C isoforms in HaCaT cells
    Mónika Gönczi
    Department of Physiology, University of Debrecen, Debrecen, Hungary
    Exp Dermatol 17:584-91. 2008
  10. ncbi request reprint Opposite roles of protein kinase C isoforms in proliferation, differentiation, apoptosis, and tumorigenicity of human HaCaT keratinocytes
    H Papp
    Department of Physiology, University of Debrecen, Nagyerdei krt 98, 4012 Debrecen, Hungary
    Cell Mol Life Sci 61:1095-105. 2004

Collaborators

  • Eniko Bodo
  • Christos C Zouboulis
  • Ralf Paus
  • L Csernoch
  • M Maurer
  • P M Blumberg
  • M Schmelz
  • C Kamei
  • M Steinhoff
  • L Misery
  • G Kunos
  • P Pacher
  • G Hasko
  • H Hashizume
  • Balazs I Toth
  • Laszlo Kovacs
  • Gabriella Czifra
  • Mónika Gönczi
  • Andrea Telek
  • Zoltán Griger
  • R Marincsák
  • Andrea Szegedi
  • Laszlo Nagy
  • Anikó Dózsa
  • Tamás Géczy
  • Edit Páyer
  • Borbala Kiss
  • Nóra Dobrosi
  • Rita Marincsák
  • G Czifra
  • L Kovacs
  • Z Rusznák
  • I Kovacs
  • H Papp
  • P Redl
  • I Tar
  • I Marton
  • Eva Rajnavolgyi
  • Szilvia Benko
  • Holger Seltmann
  • B I Tóth
  • L Toth
  • Emese Schmidt
  • Attila G Szöllosi
  • Janos Hunyadi
  • Attila Balogh
  • Zita Szikszai
  • Zsófia Kertész
  • Georgina Nagy
  • Arpád Zoltán Kiss
  • Tamas Szabo
  • Istvan Juhasz
  • Sandor Sipka
  • László Fülöp
  • István Borbíró
  • Peter P Nanasi
  • Norbert Szentandrássy
  • Gyula P Szigeti
  • Ildiko Kovacs
  • Janos Magyar
  • B Pal
  • M Aleksza
  • S Sipka
  • J Lazar
  • I Juhasz
  • G Szucs
  • A Por
  • K Pocsai
  • P Acs

Detail Information

Publications17

  1. ncbi request reprint How best to fight that nasty itch - from new insights into the neuroimmunological, neuroendocrine, and neurophysiological bases of pruritus to novel therapeutic approaches
    T Biro
    Department of Physiology, University of Debrecen, Medical and Health Sciences Center, H 4012 Debrecen, PO Box 22, Hungary
    Exp Dermatol 14:225-40. 2005
    ....
  2. doi request reprint Transient receptor potential vanilloid-1 signaling inhibits differentiation and activation of human dendritic cells
    Balazs I Toth
    Department of Physiology, University of Debrecen, Medical and Health Science Center, Research Center for Molecular Medicine, 4032 Debrecen, Nagyerdei krt 98, P O Box 22, Hungary
    FEBS Lett 583:1619-24. 2009
    ..These data introduce TRPV1-coupled signaling as a novel player in human monocyte-derived DC biology with anti-inflammatory actions...
  3. doi request reprint An "ice-cold" TR(i)P to skin biology: the role of TRPA1 in human epidermal keratinocytes
    Tamas Biro
    Department of Physiology, University of Debrecen, Research Center for Molecular Medicine, Debrecen, Hungary
    J Invest Dermatol 129:2096-9. 2009
    ....
  4. pmc The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities
    Tamas Biro
    Department of Physiology, University of Debrecen, Research Center for Molecular Medicine, Debrecen 4032, Hungary
    Trends Pharmacol Sci 30:411-20. 2009
    ..g. acne, seborrhea, allergic dermatitis, itch and pain, psoriasis, hair growth disorders, systemic sclerosis and cancer)...
  5. ncbi request reprint TRP channels as novel players in the pathogenesis and therapy of itch
    Tamas Biro
    Department of Physiology, University of Debrecen, Medical and Health Science Center, Research Center for Molecular Medicine, 4032 Debrecen, Hungary
    Biochim Biophys Acta 1772:1004-21. 2007
    ..We close by proposing a novel, TRP-centered concept of pruritus pathogenesis and sketch important future experimental directions towards the therapeutic targeting of TRP channels in the clinical management of itch...
  6. ncbi request reprint Differential distribution of TASK-1, TASK-2 and TASK-3 immunoreactivities in the rat and human cerebellum
    Z Rusznák
    Department of Physiology, Medical and Health Science Centre, University of Debrecen, 4012 Debrecen, Hungary
    Cell Mol Life Sci 61:1532-42. 2004
    ..The pia mater, astrocytes, Purkinje and granule cells demonstrated strong TASK-1 and TASK-3 positivities. The TASK-3 labelling was stronger in general, but it was particularly intense in the Purkinje cells and pia mater...
  7. doi request reprint Protein kinase C isoenzymes differentially regulate the differentiation-dependent expression of adhesion molecules in human epidermal keratinocytes
    Andrea Szegedi
    Department of Dermatology, University of Debrecen, Debrecen, Hungary
    Exp Dermatol 18:122-9. 2009
    ....
  8. doi request reprint Investigation of micronized titanium dioxide penetration in human skin xenografts and its effect on cellular functions of human skin-derived cells
    Borbala Kiss
    Department of Dermatology, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary
    Exp Dermatol 17:659-67. 2008
    ....
  9. doi request reprint Altered calcium handling following the recombinant overexpression of protein kinase C isoforms in HaCaT cells
    Mónika Gönczi
    Department of Physiology, University of Debrecen, Debrecen, Hungary
    Exp Dermatol 17:584-91. 2008
    ..The observations also suggest that different PKC isoenzymes have different effects on the phosphatidyl-inositol signalling pathway...
  10. ncbi request reprint Opposite roles of protein kinase C isoforms in proliferation, differentiation, apoptosis, and tumorigenicity of human HaCaT keratinocytes
    H Papp
    Department of Physiology, University of Debrecen, Nagyerdei krt 98, 4012 Debrecen, Hungary
    Cell Mol Life Sci 61:1095-105. 2004
    ..Our data present clear evidence for the specific, antagonistic roles of certain cPKC and nPKC isoforms in regulating the above processes in human HaCaT keratinocytes...
  11. ncbi request reprint Hypotonic stress influence the membrane potential and alter the proliferation of keratinocytes in vitro
    Mónika Gönczi
    Department of Physiology, University of Debrecen, Debrecen, Hungary
    Exp Dermatol 16:302-10. 2007
    ..These changes together with additional modifications in channel expression and intracellular signalling mechanisms could underlie the increased proliferation of keratinocytes in hyperproliferative skin diseases...
  12. doi request reprint Increased expression of TRPV1 in squamous cell carcinoma of the human tongue
    R Marincsák
    Department of Physiology, University of Debrecen, Medical and Health Science Centre, Research Centre for Molecular Medicine, Debrecen, Hungary
    Oral Dis 15:328-35. 2009
    ..In this study, we have investigated the molecular expression of TRPV1 in the human tongue and its high-incidence malignant (squamous cell carcinoma, SCC) and premalignant (leukoplakia) conditions...
  13. ncbi request reprint Inhibition of human hair follicle growth by endo- and exocannabinoids
    Andrea Telek
    Department of Physiology, University of Debrecen, Medical and Health Science Center, 4032 Debrecen, Hungary
    FASEB J 21:3534-41. 2007
    ..Finally, human HF organ culture offers an instructive, physiologically relevant new research tool for dissecting "nonclassical" effects of endocannabinoids and their receptor-mediated signaling in general...
  14. doi request reprint The analgesic drug, tramadol, acts as an agonist of the transient receptor potential vanilloid-1
    Rita Marincsák
    Department of Physiology, University of Debrecen, Medical and Health Science Center, Research Center for Molecular Medicine, 4032 Debrecen, Hungary
    Anesth Analg 106:1890-6. 2008
    ....
  15. doi request reprint Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling
    Nóra Dobrosi
    Department of Physiology, University of Debrecen, Medical and Health Science Center, 4032 Debrecen, Nagyerdei krt 98 PO Box 22, Hungary
    FASEB J 22:3685-95. 2008
    ..CB2 antagonists or agonists therefore deserve to be explored in the management of skin disorders characterized by sebaceous gland dysfunctions (e.g., acne vulgaris, seborrhea, dry skin)...
  16. ncbi request reprint Protein kinase C-beta and -delta isoenzymes promote arachidonic acid production and proliferation of MonoMac-6 cells
    Zoltán Griger
    Department of Physiology, University of Debrecen, Research Center for Molecular Medicine, Medical and Health Science Center, Nagyerdei krt 98, 4032, Debrecen, Hungary
    J Mol Med (Berl) 85:1031-42. 2007
    ....
  17. doi request reprint Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biology
    Balazs I Toth
    Department of Physiology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
    J Invest Dermatol 129:329-39. 2009
    ....