Research Topics
| T BiroSummaryAffiliation: University of Debrecen Country: Hungary Publications
| Collaborators
|
Detail Information
Publications
Transient receptor potential vanilloid-1 signaling inhibits differentiation and activation of human dendritic cellsBalazs I Toth
Department of Physiology, University of Debrecen, Medical and Health Science Center, Research Center for Molecular Medicine, 4032 Debrecen, Nagyerdei krt 98, P O Box 22, Hungary
FEBS Lett 583:1619-24. 2009..These data introduce TRPV1-coupled signaling as a novel player in human monocyte-derived DC biology with anti-inflammatory actions...
An "ice-cold" TR(i)P to skin biology: the role of TRPA1 in human epidermal keratinocytesTamas Biro
Department of Physiology, University of Debrecen, Research Center for Molecular Medicine, Debrecen, Hungary
J Invest Dermatol 129:2096-9. 2009....
How best to fight that nasty itch - from new insights into the neuroimmunological, neuroendocrine, and neurophysiological bases of pruritus to novel therapeutic approachesT Biro
Department of Physiology, University of Debrecen, Medical and Health Sciences Center, H 4012 Debrecen, PO Box 22, Hungary
Exp Dermatol 14:225-40. 2005....
The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunitiesTamas Biro
Department of Physiology, University of Debrecen, Research Center for Molecular Medicine, Debrecen 4032, Hungary
Trends Pharmacol Sci 30:411-20. 2009..g. acne, seborrhea, allergic dermatitis, itch and pain, psoriasis, hair growth disorders, systemic sclerosis and cancer)...
TRP channels as novel players in the pathogenesis and therapy of itchTamas Biro
Department of Physiology, University of Debrecen, Medical and Health Science Center, Research Center for Molecular Medicine, 4032 Debrecen, Hungary
Biochim Biophys Acta 1772:1004-21. 2007..We close by proposing a novel, TRP-centered concept of pruritus pathogenesis and sketch important future experimental directions towards the therapeutic targeting of TRP channels in the clinical management of itch...
Differential distribution of TASK-1, TASK-2 and TASK-3 immunoreactivities in the rat and human cerebellumZ Rusznák
Department of Physiology, Medical and Health Science Centre, University of Debrecen, 4012 Debrecen, Hungary
Cell Mol Life Sci 61:1532-42. 2004..The pia mater, astrocytes, Purkinje and granule cells demonstrated strong TASK-1 and TASK-3 positivities. The TASK-3 labelling was stronger in general, but it was particularly intense in the Purkinje cells and pia mater...
Protein kinase C isoenzymes differentially regulate the differentiation-dependent expression of adhesion molecules in human epidermal keratinocytesAndrea Szegedi
Department of Dermatology, University of Debrecen, Debrecen, Hungary
Exp Dermatol 18:122-9. 2009....
Altered calcium handling following the recombinant overexpression of protein kinase C isoforms in HaCaT cellsMónika Gönczi
Department of Physiology, University of Debrecen, Debrecen, Hungary
Exp Dermatol 17:584-91. 2008..The observations also suggest that different PKC isoenzymes have different effects on the phosphatidyl-inositol signalling pathway...
Investigation of micronized titanium dioxide penetration in human skin xenografts and its effect on cellular functions of human skin-derived cellsBorbala Kiss
Department of Dermatology, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary
Exp Dermatol 17:659-67. 2008....
Hypotonic stress influence the membrane potential and alter the proliferation of keratinocytes in vitroMónika Gönczi
Department of Physiology, University of Debrecen, Debrecen, Hungary
Exp Dermatol 16:302-10. 2007..These changes together with additional modifications in channel expression and intracellular signalling mechanisms could underlie the increased proliferation of keratinocytes in hyperproliferative skin diseases...
Increased expression of TRPV1 in squamous cell carcinoma of the human tongueR Marincsák
Department of Physiology, University of Debrecen, Medical and Health Science Centre, Research Centre for Molecular Medicine, Debrecen, Hungary
Oral Dis 15:328-35. 2009..In this study, we have investigated the molecular expression of TRPV1 in the human tongue and its high-incidence malignant (squamous cell carcinoma, SCC) and premalignant (leukoplakia) conditions...
Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biologyBalazs I Toth
Department of Physiology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
J Invest Dermatol 129:329-39. 2009....
Inhibition of human hair follicle growth by endo- and exocannabinoidsAndrea Telek
Department of Physiology, University of Debrecen, Medical and Health Science Center, 4032 Debrecen, Hungary
FASEB J 21:3534-41. 2007..Finally, human HF organ culture offers an instructive, physiologically relevant new research tool for dissecting "nonclassical" effects of endocannabinoids and their receptor-mediated signaling in general...
Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signalingNóra Dobrosi
Department of Physiology, University of Debrecen, Medical and Health Science Center, 4032 Debrecen, Nagyerdei krt 98 PO Box 22, Hungary
FASEB J 22:3685-95. 2008..CB2 antagonists or agonists therefore deserve to be explored in the management of skin disorders characterized by sebaceous gland dysfunctions (e.g., acne vulgaris, seborrhea, dry skin)...
Protein kinase C-beta and -delta isoenzymes promote arachidonic acid production and proliferation of MonoMac-6 cellsZoltán Griger
Department of Physiology, University of Debrecen, Research Center for Molecular Medicine, Medical and Health Science Center, Nagyerdei krt 98, 4032, Debrecen, Hungary
J Mol Med (Berl) 85:1031-42. 2007....
The analgesic drug, tramadol, acts as an agonist of the transient receptor potential vanilloid-1Rita Marincsák
Department of Physiology, University of Debrecen, Medical and Health Science Center, Research Center for Molecular Medicine, 4032 Debrecen, Hungary
Anesth Analg 106:1890-6. 2008....
