A Zalatnai

Summary

Affiliation: Semmelweis University
Country: Hungary

Publications

  1. ncbi request reprint Review: potential role of cell cycle synchronizing agents in combination treatment modalities of malignant tumors
    Attila Zalatnai
    First Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    In Vivo 19:85-91. 2005
  2. ncbi request reprint Vascular activity of two silicon compounds, ALIS 409 and ALIS 421, novel multidrug-resistance reverting agents in cancer cells
    Fabio Fusi
    Dipartimento di Scienze Biomediche, Universita degli Studi di Siena, Via A Moro 2, 53100 Siena, Italy
    Cancer Chemother Pharmacol 61:443-51. 2008
  3. pmc Validation of diagnostic accuracy using digital slides in routine histopathology
    Laszlo Fonyad
    First Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
    Diagn Pathol 7:35. 2012
  4. ncbi request reprint Pancreatic cancer - a continuing challenge in oncology
    Attila Zalatnai
    1st Department of Pathology and Experimental Cancer Research, Faculty of Medicine Semmelweis University, H 1085 Budapest, Hungary
    Pathol Oncol Res 9:252-63. 2003
  5. ncbi request reprint [Intraepithelial neoplasm of the pancreas]
    Attila Zalatnai
    Semmelweis Egyetem Altalános Orvostudományi Kar, I sz Patológiai és Kísérleti Rákkutató Intézet, Budapest
    Orv Hetil 145:19-23. 2004
  6. ncbi request reprint [Diagnostic difficulties in kidney cancer filling up the retroperitoneal space]
    Attila Zalatnai
    Semmelweis Egyetem, Altalanos Orvostudomanyi, Kar, I Patológiai és Kisérleti Rákkutató Intézete, Budapest
    Orv Hetil 146:701-5. 2005
  7. ncbi request reprint P-glycoprotein expression is induced in human pancreatic cancer xenografts during treatment with a cell cycle regulator, mimosine
    Attila Zalatnai
    1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, Budapest, H 1085, Hungary
    Pathol Oncol Res 11:164-9. 2005
  8. ncbi request reprint Effect of SILA-409, a new organosilicon multidrug resistance modifier, on human pancreatic cancer xenografts
    Attila Zalatnai
    Semmelweis University, Faculty of Medicine, First Department of Pathology and Experimental Cancer Research, Budapest, Hungary
    In Vivo 20:137-40. 2006
  9. ncbi request reprint [Familial pancreatic cancer]
    Attila Zalatnai
    I sz Patológiai és Kísérleti Rákkutató Intézet, Semmelweis Egyetem AOK, Budapest, Hungary
    Magy Onkol 50:163-8. 2006
  10. ncbi request reprint Short-term octreotide treatment induces apoptosis in human pancreatic cancer xenografts
    Attila Zalatnai
    Semmelweis University, Faculty of Medicine, First Department of Pathology and Experimental Cancer Research, Budapest, Hungary
    In Vivo 20:549-52. 2006

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Review: potential role of cell cycle synchronizing agents in combination treatment modalities of malignant tumors
    Attila Zalatnai
    First Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    In Vivo 19:85-91. 2005
    ..Moreover, after encouraging preclinical investigations, the combination of cell cycle regulators with different cytostatic drugs may offer a novel therapeutic alternative in the field of oncology...
  2. ncbi request reprint Vascular activity of two silicon compounds, ALIS 409 and ALIS 421, novel multidrug-resistance reverting agents in cancer cells
    Fabio Fusi
    Dipartimento di Scienze Biomediche, Universita degli Studi di Siena, Via A Moro 2, 53100 Siena, Italy
    Cancer Chemother Pharmacol 61:443-51. 2008
    ....
  3. pmc Validation of diagnostic accuracy using digital slides in routine histopathology
    Laszlo Fonyad
    First Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
    Diagn Pathol 7:35. 2012
    ..Reports have been advocated the reliability of digital slides in routine diagnostics. We have designed a retrospective, comparative study to evaluate the scanning properties and digital slide based diagnostic accuracy...
  4. ncbi request reprint Pancreatic cancer - a continuing challenge in oncology
    Attila Zalatnai
    1st Department of Pathology and Experimental Cancer Research, Faculty of Medicine Semmelweis University, H 1085 Budapest, Hungary
    Pathol Oncol Res 9:252-63. 2003
    ..Finally, the paper outlines the available data about the possibility of chemoprevention, including the role of cyclooxygenase inhibitors...
  5. ncbi request reprint [Intraepithelial neoplasm of the pancreas]
    Attila Zalatnai
    Semmelweis Egyetem Altalános Orvostudományi Kar, I sz Patológiai és Kísérleti Rákkutató Intézet, Budapest
    Orv Hetil 145:19-23. 2004
    ..Moreover, researchers employed several dozens of terminologies preventing the comparison between the results of different groups...
  6. ncbi request reprint [Diagnostic difficulties in kidney cancer filling up the retroperitoneal space]
    Attila Zalatnai
    Semmelweis Egyetem, Altalanos Orvostudomanyi, Kar, I Patológiai és Kisérleti Rákkutató Intézete, Budapest
    Orv Hetil 146:701-5. 2005
    ..The author discusses the pitfalls of diagnosis from clinicopathological point of view...
  7. ncbi request reprint P-glycoprotein expression is induced in human pancreatic cancer xenografts during treatment with a cell cycle regulator, mimosine
    Attila Zalatnai
    1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, Budapest, H 1085, Hungary
    Pathol Oncol Res 11:164-9. 2005
    ..The results indicate that P-glycoprotein is inducible by a cell cycle regulator, creating an acquired resistant phenotype...
  8. ncbi request reprint Effect of SILA-409, a new organosilicon multidrug resistance modifier, on human pancreatic cancer xenografts
    Attila Zalatnai
    Semmelweis University, Faculty of Medicine, First Department of Pathology and Experimental Cancer Research, Budapest, Hungary
    In Vivo 20:137-40. 2006
    ..The efficacy of this organosilicon drug was investigated in vivo, in a xenograft system...
  9. ncbi request reprint [Familial pancreatic cancer]
    Attila Zalatnai
    I sz Patológiai és Kísérleti Rákkutató Intézet, Semmelweis Egyetem AOK, Budapest, Hungary
    Magy Onkol 50:163-8. 2006
    ..Considering the very high (and continuously increasing) incidence, it seems to be necessary to register and screen these families. This review emphasizes the importance of these goals...
  10. ncbi request reprint Short-term octreotide treatment induces apoptosis in human pancreatic cancer xenografts
    Attila Zalatnai
    Semmelweis University, Faculty of Medicine, First Department of Pathology and Experimental Cancer Research, Budapest, Hungary
    In Vivo 20:549-52. 2006
    ..In the present study the effect of smaller doses (2x100 microg/kg b.w.) administered in a short-term (4-day) experiment were investigated...
  11. ncbi request reprint Molecular aspects of stromal-parenchymal interactions in malignant neoplasms
    Attila Zalatnai
    First Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    Curr Mol Med 6:685-93. 2006
    ....
  12. ncbi request reprint Novel therapeutic approaches in the treatment of advanced pancreatic carcinoma
    A Zalatnai
    Semmelweis University, Faculty of Medicine, First Institute of Pathology and Experimental Cancer Research, H 1085 Budapest, Ulloi 26, Hungary
    Cancer Treat Rev 33:289-98. 2007
    ..Pancreatic adenocarcinoma remains a great challenge for the oncologists, and continuous search for better molecules and/or combinations is inevitable...
  13. ncbi request reprint Review. Molecular background of chemoresistance in pancreatic cancer
    Attila Zalatnai
    Semmelweis University, Faculty of Medicine, First Department of Pathology and Experimental Cancer Research, Budapest, Hungary
    In Vivo 21:339-47. 2007
    ..The reversal of the drug resistance is an area of intensive investigation, but to date, the compounds investigated are effective mainly in experimental systems and prospective studies are needed to validate their clinical applicability...
  14. ncbi request reprint Mimosine, a plant-derived amino acid induces apoptosis in human pancreatic cancer xenografts
    Attila Zalatnai
    First Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, H 1085 Budapest, Ulloi ut 26, Hungary
    Anticancer Res 23:4007-9. 2003
    ..This study revealed a tumor growth suppression and an increased apoptotic index. Our experiment was aimed at investigating the influence of mimosine in human pancreatic cancer...
  15. ncbi request reprint Primary malignant melanoma of adrenal gland in a 41-yr-old woman
    Attila Zalatnai
    Semmelweis University, Faculty of Medicine, First Department of Pathology and Experimental Cancer Research, Budapest, Hungary
    Endocr Pathol 14:101-5. 2003
  16. ncbi request reprint Human pancreatic leiomyosarcoma (PZX-7) growing as a serially transplantable xenograft in immunosuppressed mice
    A Zalatnai
    1st Institute of Pathology and Experimental Medicine, Budapest, Hungary
    Int J Pancreatol 26:33-41. 1999
    ..Several human leiomyosarcoma xenografts have been established, but pancreatic smooth muscle sarcomas have never been serially transplanted and investigated...
  17. ncbi request reprint Epidermal growth factor receptor, somatostatin and bcl-2 in human pancreatic tumor xenografts. An immunohistochemical study
    A Zalatnai
    Semmelweis University of Medicine, First Institute of Pathology and Experimental Cancer Research Ulloi út 26, Budapest, H 1085, Hungary
    Pathol Oncol Res 5:146-51. 1999
    ..In the PZX-5 carcinoma line that was originally negative, the one month Sandostatin treatment induced the strong expression of bcl-2 protein suggesting a development of an acquired resistance against programmed cell death in this tumor...
  18. ncbi request reprint Flow cytometric evidence of apoptosis in human pancreatic cancer xenografts treated with Sandostatin (octreotide)
    A Zalatnai
    First Institute of Pathology and Experimental Cancer Research, Semmelweis University of Medicine, Budapest VIII, Hungary
    Anticancer Res 20:1663-6. 2000
    ..In this work, apoptosis was assessed in human pancreatic carcinoma xenografts after a 4-week high-dose Sandostatin treatment...
  19. ncbi request reprint Coccidioidomycosis in Hungary. The first import case
    A Zalatnai
    Semmelweis University of Medicine, Frist Institute of Pathology and Experimental Cancer Research, Budapest, Hungary
    Pathol Oncol Res 4:147-51. 1998
    ..This represents the first imported case of coccidioidomycosis in Hungary...
  20. ncbi request reprint Wheat germ extract inhibits experimental colon carcinogenesis in F-344 rats
    A Zalatnai
    1st Institute of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
    Carcinogenesis 22:1649-52. 2001
    ..004), group 4 - 0 and 0. All the tumors were of neoplastic nature also histologically. The numbers of the aberrant crypt foci (ACF) per area (cm(2)) in group 2 were 4.85 while in group 3 the ACF numbers were 2.03 only (P < 0.0001)...
  21. ncbi request reprint [Pathologic diagnosis of pancreatic cancer--facts, pitfalls, challenges]
    A Zalatnai
    Általános Orvostudományi Kar, I Patológiai és Kísérleti Rákkutató Intézet, Semmelweis Egyetem, Budapest
    Orv Hetil 142:1885-90. 2001
    ..To date, molecular pathological methods have shown no advantage in the differential diagnosis...
  22. ncbi request reprint Pancreatic leiomyosarcoma. Case report with immunohistochemical and flow cytometric studies
    A Zalatnai
    1st Institute of Pathology and Experimental Cancer Research, Semmelweis University of Medicine, Budapest, Hungary
    Virchows Arch 432:469-72. 1998
    ..Flow cytometric analysis revealed an aneuploid pattern (DNA index: 1,561). The patient died with widespread metastases 7 month after the operation...
  23. ncbi request reprint Papillary microcarcinoma of the thyroid gland in renal transplant patients
    B Nemes
    Semmelweis University, Department of Transplantation and Surgery Baross u 23, Budapest, H 1082, Hungary
    Pathol Oncol Res 6:72-5. 2000
    ..Metastatic tumor is relatively benign which is in correlation with the literature, but there has been little experience in organ transplanted patients so far...
  24. ncbi request reprint Apoptosis-induction and phosphorylation state in human pancreatic carcinoma xenografts following octreotide treatment
    A Zalatnai
    1st Institute of Pathology and Experimental Cancer Research, Semmelweis University, H 1085 Budapest, Ulloi ut 26, Hungary
    Anticancer Res 21:477-80. 2001
    ..Some exocrine pancreatic carcinomas are responsive to hormonal manipulations, but the mechanism is not fully understood...
  25. ncbi request reprint Agrin, a novel basement membrane component in human and rat liver, accumulates in cirrhosis and hepatocellular carcinoma
    Péter Tátrai
    11st Institute of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
    Lab Invest 86:1149-60. 2006
    ....
  26. ncbi request reprint In vitro antiangiogenic effect of sandostatin (octreotide) on the proliferation of the placental vessels
    Attila Zalatnai
    First Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, H 1085 Budapest, Hungary
    Anticancer Res 22:4225-7. 2002
    ..We investigated the potential angio-inhibiting activity of this drug in an in vitro system using human placental fragments...
  27. ncbi request reprint Genomics of pancreatic cancer: does it make any improvement in diagnosis, prognosis and therapy?
    Laszlo Kopper
    1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, H 1085, Hungary
    Pathol Oncol Res 11:69-73. 2005
    ..Our increasing knowledge on the molecular targets in various cancer types started to change their management. Examples of success of the molecular therapies (in CML, GIST, NSCLC) may initiate more activity in pancreatic cancer as well...
  28. doi request reprint Overexpression of glucocorticoid receptor in human pancreatic cancer and in xenografts. An immunohistochemical study
    Sandor Bekasi
    First Department of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, Ulloi ut 26, 1085, Budapest, Hungary
    Pathol Oncol Res 15:561-6. 2009
    ..Our studies have shown that the human pancreatic carcinomas do overexpress a strong glucocorticoid receptor positivity, but its significance is not clear. However, this finding might have a clinical relevance...
  29. ncbi request reprint Appearance of fibronectin in putative preneoplastic lesions and in hepatocellular carcinoma during chemical hepatocarcinogenesis in rats and in human hepatomas
    M Szendroi
    1st Institute of Pathology and Experimental Cancer Research, Semmelweis University Medical School, Budapest, Hungary
    J Exp Pathol 1:189-99. 1984
    ....
  30. ncbi request reprint Secondary cutaneous infiltration in B cell chronic lymphocytic leukemia
    J Varkonyi
    3rd Department of Internal Medicine, Semmelweis University of Medicine, Budapest, Hungary
    Acta Haematol 103:116-21. 2000
    ..The changing character of the disease raises the possibility of a second mutational event in the course of B-CLL...
  31. ncbi request reprint MRI for the evaluation of scleral invasion and extrascleral extension of uveal melanomas
    Zsuzsa Recsan
    Second Department of Ophthalmology, Faculty Medicine, Semmelweis University, Budapest, Hungary
    Clin Radiol 57:371-6. 2002
    ..To study the diagnostic value of MRI for the detection of scleral infiltration and extrascleral extension of uveal melanoma...
  32. doi request reprint [Verner-Morrison syndrome: a case study]
    Csaba Halászlaki
    Semmelweis Egyetem, Általános Orvostudományi Kar, I Belgyógyászati Klinika, Budapest
    Orv Hetil 151:1111-4. 2010
    ..Early diagnosis and management may affect survival of patients favorably. VIPoma cases may be associated with multiple endocrine neoplasia type 1...
  33. ncbi request reprint Correlation of ultrasound attenuation and histopathological parameters of the liver in chronic diffuse liver diseases
    Agnes Szebeni
    Ultrasound Laboratory, 1st Internal Department, MI Central Hospital and 1st Department of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, Budapest, Hungary
    Eur J Gastroenterol Hepatol 18:37-42. 2006
    ..Correlation was studied between liver attenuation and histopathological analysis of biopsy specimens of the same patients...