Research Topics
| A ZalatnaiSummaryAffiliation: Semmelweis University Country: Hungary Publications
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Detail Information
Publications
Review: potential role of cell cycle synchronizing agents in combination treatment modalities of malignant tumorsAttila Zalatnai
First Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, Budapest, Hungary
In Vivo 19:85-91. 2005..Moreover, after encouraging preclinical investigations, the combination of cell cycle regulators with different cytostatic drugs may offer a novel therapeutic alternative in the field of oncology...- Vascular activity of two silicon compounds, ALIS 409 and ALIS 421, novel multidrug-resistance reverting agents in cancer cellsFabio Fusi
Dipartimento di Scienze Biomediche, Universita degli Studi di Siena, Via A Moro 2, 53100 Siena, Italy
Cancer Chemother Pharmacol 61:443-51. 2008.... - Validation of diagnostic accuracy using digital slides in routine histopathologyLaszlo Fonyad
First Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
Diagn Pathol 7:35. 2012..Reports have been advocated the reliability of digital slides in routine diagnostics. We have designed a retrospective, comparative study to evaluate the scanning properties and digital slide based diagnostic accuracy... - Pancreatic cancer - a continuing challenge in oncologyAttila Zalatnai
1st Department of Pathology and Experimental Cancer Research, Faculty of Medicine Semmelweis University, H 1085 Budapest, Hungary
Pathol Oncol Res 9:252-63. 2003..Finally, the paper outlines the available data about the possibility of chemoprevention, including the role of cyclooxygenase inhibitors... - [Intraepithelial neoplasm of the pancreas]Attila Zalatnai
Semmelweis Egyetem Altalános Orvostudományi Kar, I sz Patológiai és Kísérleti Rákkutató Intézet, Budapest
Orv Hetil 145:19-23. 2004..Moreover, researchers employed several dozens of terminologies preventing the comparison between the results of different groups... - [Diagnostic difficulties in kidney cancer filling up the retroperitoneal space]Attila Zalatnai
Semmelweis Egyetem, Altalanos Orvostudomanyi, Kar, I Patológiai és Kisérleti Rákkutató Intézete, Budapest
Orv Hetil 146:701-5. 2005..The author discusses the pitfalls of diagnosis from clinicopathological point of view... - P-glycoprotein expression is induced in human pancreatic cancer xenografts during treatment with a cell cycle regulator, mimosineAttila Zalatnai
1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, Budapest, H 1085, Hungary
Pathol Oncol Res 11:164-9. 2005..The results indicate that P-glycoprotein is inducible by a cell cycle regulator, creating an acquired resistant phenotype... - Effect of SILA-409, a new organosilicon multidrug resistance modifier, on human pancreatic cancer xenograftsAttila Zalatnai
Semmelweis University, Faculty of Medicine, First Department of Pathology and Experimental Cancer Research, Budapest, Hungary
In Vivo 20:137-40. 2006..The efficacy of this organosilicon drug was investigated in vivo, in a xenograft system... - [Familial pancreatic cancer]Attila Zalatnai
I sz Patológiai és Kísérleti Rákkutató Intézet, Semmelweis Egyetem AOK, Budapest, Hungary
Magy Onkol 50:163-8. 2006..Considering the very high (and continuously increasing) incidence, it seems to be necessary to register and screen these families. This review emphasizes the importance of these goals... - Short-term octreotide treatment induces apoptosis in human pancreatic cancer xenograftsAttila Zalatnai
Semmelweis University, Faculty of Medicine, First Department of Pathology and Experimental Cancer Research, Budapest, Hungary
In Vivo 20:549-52. 2006..In the present study the effect of smaller doses (2x100 microg/kg b.w.) administered in a short-term (4-day) experiment were investigated... - Molecular aspects of stromal-parenchymal interactions in malignant neoplasmsAttila Zalatnai
First Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, Budapest, Hungary
Curr Mol Med 6:685-93. 2006.... - Novel therapeutic approaches in the treatment of advanced pancreatic carcinomaA Zalatnai
Semmelweis University, Faculty of Medicine, First Institute of Pathology and Experimental Cancer Research, H 1085 Budapest, Ulloi 26, Hungary
Cancer Treat Rev 33:289-98. 2007..Pancreatic adenocarcinoma remains a great challenge for the oncologists, and continuous search for better molecules and/or combinations is inevitable... - Review. Molecular background of chemoresistance in pancreatic cancerAttila Zalatnai
Semmelweis University, Faculty of Medicine, First Department of Pathology and Experimental Cancer Research, Budapest, Hungary
In Vivo 21:339-47. 2007..The reversal of the drug resistance is an area of intensive investigation, but to date, the compounds investigated are effective mainly in experimental systems and prospective studies are needed to validate their clinical applicability... - Mimosine, a plant-derived amino acid induces apoptosis in human pancreatic cancer xenograftsAttila Zalatnai
First Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, H 1085 Budapest, Ulloi ut 26, Hungary
Anticancer Res 23:4007-9. 2003..This study revealed a tumor growth suppression and an increased apoptotic index. Our experiment was aimed at investigating the influence of mimosine in human pancreatic cancer... - Primary malignant melanoma of adrenal gland in a 41-yr-old womanAttila Zalatnai
Semmelweis University, Faculty of Medicine, First Department of Pathology and Experimental Cancer Research, Budapest, Hungary
Endocr Pathol 14:101-5. 2003 - Human pancreatic leiomyosarcoma (PZX-7) growing as a serially transplantable xenograft in immunosuppressed miceA Zalatnai
1st Institute of Pathology and Experimental Medicine, Budapest, Hungary
Int J Pancreatol 26:33-41. 1999..Several human leiomyosarcoma xenografts have been established, but pancreatic smooth muscle sarcomas have never been serially transplanted and investigated... - Epidermal growth factor receptor, somatostatin and bcl-2 in human pancreatic tumor xenografts. An immunohistochemical studyA Zalatnai
Semmelweis University of Medicine, First Institute of Pathology and Experimental Cancer Research Ulloi út 26, Budapest, H 1085, Hungary
Pathol Oncol Res 5:146-51. 1999..In the PZX-5 carcinoma line that was originally negative, the one month Sandostatin treatment induced the strong expression of bcl-2 protein suggesting a development of an acquired resistance against programmed cell death in this tumor... - Flow cytometric evidence of apoptosis in human pancreatic cancer xenografts treated with Sandostatin (octreotide)A Zalatnai
First Institute of Pathology and Experimental Cancer Research, Semmelweis University of Medicine, Budapest VIII, Hungary
Anticancer Res 20:1663-6. 2000..In this work, apoptosis was assessed in human pancreatic carcinoma xenografts after a 4-week high-dose Sandostatin treatment... - Coccidioidomycosis in Hungary. The first import caseA Zalatnai
Semmelweis University of Medicine, Frist Institute of Pathology and Experimental Cancer Research, Budapest, Hungary
Pathol Oncol Res 4:147-51. 1998..This represents the first imported case of coccidioidomycosis in Hungary... - Wheat germ extract inhibits experimental colon carcinogenesis in F-344 ratsA Zalatnai
1st Institute of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
Carcinogenesis 22:1649-52. 2001..004), group 4 - 0 and 0. All the tumors were of neoplastic nature also histologically. The numbers of the aberrant crypt foci (ACF) per area (cm(2)) in group 2 were 4.85 while in group 3 the ACF numbers were 2.03 only (P < 0.0001)... - [Pathologic diagnosis of pancreatic cancer--facts, pitfalls, challenges]A Zalatnai
Általános Orvostudományi Kar, I Patológiai és Kísérleti Rákkutató Intézet, Semmelweis Egyetem, Budapest
Orv Hetil 142:1885-90. 2001..To date, molecular pathological methods have shown no advantage in the differential diagnosis... - Pancreatic leiomyosarcoma. Case report with immunohistochemical and flow cytometric studiesA Zalatnai
1st Institute of Pathology and Experimental Cancer Research, Semmelweis University of Medicine, Budapest, Hungary
Virchows Arch 432:469-72. 1998..Flow cytometric analysis revealed an aneuploid pattern (DNA index: 1,561). The patient died with widespread metastases 7 month after the operation... - Papillary microcarcinoma of the thyroid gland in renal transplant patientsB Nemes
Semmelweis University, Department of Transplantation and Surgery Baross u 23, Budapest, H 1082, Hungary
Pathol Oncol Res 6:72-5. 2000..Metastatic tumor is relatively benign which is in correlation with the literature, but there has been little experience in organ transplanted patients so far... - Apoptosis-induction and phosphorylation state in human pancreatic carcinoma xenografts following octreotide treatmentA Zalatnai
1st Institute of Pathology and Experimental Cancer Research, Semmelweis University, H 1085 Budapest, Ulloi ut 26, Hungary
Anticancer Res 21:477-80. 2001..Some exocrine pancreatic carcinomas are responsive to hormonal manipulations, but the mechanism is not fully understood... - Agrin, a novel basement membrane component in human and rat liver, accumulates in cirrhosis and hepatocellular carcinomaPéter Tátrai
11st Institute of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
Lab Invest 86:1149-60. 2006.... - In vitro antiangiogenic effect of sandostatin (octreotide) on the proliferation of the placental vesselsAttila Zalatnai
First Department of Pathology and Experimental Cancer Research, Semmelweis University, Faculty of Medicine, H 1085 Budapest, Hungary
Anticancer Res 22:4225-7. 2002..We investigated the potential angio-inhibiting activity of this drug in an in vitro system using human placental fragments... - Genomics of pancreatic cancer: does it make any improvement in diagnosis, prognosis and therapy?Laszlo Kopper
1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, H 1085, Hungary
Pathol Oncol Res 11:69-73. 2005..Our increasing knowledge on the molecular targets in various cancer types started to change their management. Examples of success of the molecular therapies (in CML, GIST, NSCLC) may initiate more activity in pancreatic cancer as well... - Overexpression of glucocorticoid receptor in human pancreatic cancer and in xenografts. An immunohistochemical studySandor Bekasi
First Department of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, Ulloi ut 26, 1085, Budapest, Hungary
Pathol Oncol Res 15:561-6. 2009..Our studies have shown that the human pancreatic carcinomas do overexpress a strong glucocorticoid receptor positivity, but its significance is not clear. However, this finding might have a clinical relevance... - Secondary cutaneous infiltration in B cell chronic lymphocytic leukemiaJ Varkonyi
3rd Department of Internal Medicine, Semmelweis University of Medicine, Budapest, Hungary
Acta Haematol 103:116-21. 2000..The changing character of the disease raises the possibility of a second mutational event in the course of B-CLL... - [Verner-Morrison syndrome: a case study]Csaba Halászlaki
Semmelweis Egyetem, Általános Orvostudományi Kar, I Belgyógyászati Klinika, Budapest
Orv Hetil 151:1111-4. 2010..Early diagnosis and management may affect survival of patients favorably. VIPoma cases may be associated with multiple endocrine neoplasia type 1... - Correlation of ultrasound attenuation and histopathological parameters of the liver in chronic diffuse liver diseasesAgnes Szebeni
Ultrasound Laboratory, 1st Internal Department, MI Central Hospital and 1st Department of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, Budapest, Hungary
Eur J Gastroenterol Hepatol 18:37-42. 2006..Correlation was studied between liver attenuation and histopathological analysis of biopsy specimens of the same patients...