Ferenc Sipos

Summary

Affiliation: Semmelweis University
Country: Hungary

Publications

  1. doi request reprint Regeneration associated growth factor receptor and epithelial marker expression in lymphoid aggregates of ulcerative colitis
    Ferenc Sipos
    2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    Scand J Gastroenterol 45:440-8. 2010
  2. ncbi request reprint Elevated insulin-like growth factor 1 receptor, hepatocyte growth factor receptor and telomerase protein expression in mild ulcerative colitis
    Ferenc Sipos
    and Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    Scand J Gastroenterol 43:289-98. 2008
  3. ncbi request reprint Growth in epithelial cell proliferation and apoptosis correlates specifically to the inflammation activity of inflammatory bowel diseases: ulcerative colitis shows specific p53- and EGFR expression alterations
    Ferenc Sipos
    2nd Department of Medicine, Semmelweis University, Budapest, Hungary
    Dis Colon Rectum 48:775-86. 2005
  4. ncbi request reprint [Use of DNA-chips technology in colorectal cancer]
    Ferenc Sipos
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 145:993-9. 2004
  5. doi request reprint The possible role of isolated lymphoid follicles in colonic mucosal repair
    Ferenc Sipos
    2nd Department of Internal Medicine, Cell Analysis Laboratory, Semmelweis University, 1088, Budapest, Szentkiralyi Street 46, Hungary
    Pathol Oncol Res 16:11-8. 2010
  6. doi request reprint Increase of α-SMA(+) and CK (+) cells as an early sign of epithelial-mesenchymal transition during colorectal carcinogenesis
    Gábor Valcz
    Cell Analysis Laboratory, 2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    Pathol Oncol Res 18:371-6. 2012
  7. doi request reprint The influence of methylated septin 9 gene on RNA and protein level in colorectal cancer
    Kinga Tóth
    Semmelweis University, 2nd Department of Internal Medicine, Budapest, Hungary
    Pathol Oncol Res 17:503-9. 2011
  8. pmc Applicability of antibody and mRNA expression microarrays for identifying diagnostic and progression markers of early and late stage colorectal cancer
    Sandor Spisak
    2nd Department of Medicine, Semmelweis University, Budapest, Hungary
    Dis Markers 28:1-14. 2010
  9. doi request reprint Lymphoid aggregates may contribute to the migration and epithelial commitment of bone marrow-derived cells in colonic mucosa
    Gábor Valcz
    2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    J Clin Pathol 64:771-5. 2011
  10. doi request reprint Diagnostic mRNA expression patterns of inflamed, benign, and malignant colorectal biopsy specimen and their correlation with peripheral blood results
    Orsolya Galamb
    2nd Department of Medicine, Semmelweis University, Szentkiralyi str 46, 1088 Budapest, Hungary
    Cancer Epidemiol Biomarkers Prev 17:2835-45. 2008

Detail Information

Publications68

  1. doi request reprint Regeneration associated growth factor receptor and epithelial marker expression in lymphoid aggregates of ulcerative colitis
    Ferenc Sipos
    2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    Scand J Gastroenterol 45:440-8. 2010
    ....
  2. ncbi request reprint Elevated insulin-like growth factor 1 receptor, hepatocyte growth factor receptor and telomerase protein expression in mild ulcerative colitis
    Ferenc Sipos
    and Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    Scand J Gastroenterol 43:289-98. 2008
    ..We assayed the expression alterations of regenerative signal receptors and cell-aging inhibitory systems within colonic crypts by considering the histological activity of the disease...
  3. ncbi request reprint Growth in epithelial cell proliferation and apoptosis correlates specifically to the inflammation activity of inflammatory bowel diseases: ulcerative colitis shows specific p53- and EGFR expression alterations
    Ferenc Sipos
    2nd Department of Medicine, Semmelweis University, Budapest, Hungary
    Dis Colon Rectum 48:775-86. 2005
    ..Epithelial cell turnover related differences between ulcerative colitis, Crohn's colitis, and aspecific colitis are not known yet...
  4. ncbi request reprint [Use of DNA-chips technology in colorectal cancer]
    Ferenc Sipos
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 145:993-9. 2004
    ....
  5. doi request reprint The possible role of isolated lymphoid follicles in colonic mucosal repair
    Ferenc Sipos
    2nd Department of Internal Medicine, Cell Analysis Laboratory, Semmelweis University, 1088, Budapest, Szentkiralyi Street 46, Hungary
    Pathol Oncol Res 16:11-8. 2010
    ..Our aim is to review the relation of ILFs to the different elements of colonic mucosal repair...
  6. doi request reprint Increase of α-SMA(+) and CK (+) cells as an early sign of epithelial-mesenchymal transition during colorectal carcinogenesis
    Gábor Valcz
    Cell Analysis Laboratory, 2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    Pathol Oncol Res 18:371-6. 2012
    ..The negative correlation between E-cadherin and intraepithelial α-SMA expression suggests that EMT is facilitated by a loss of epithelial cell contact...
  7. doi request reprint The influence of methylated septin 9 gene on RNA and protein level in colorectal cancer
    Kinga Tóth
    Semmelweis University, 2nd Department of Internal Medicine, Budapest, Hungary
    Pathol Oncol Res 17:503-9. 2011
    ..These changes can be reversed by demethylation agents converting this screening marker gene into therapeutic target...
  8. pmc Applicability of antibody and mRNA expression microarrays for identifying diagnostic and progression markers of early and late stage colorectal cancer
    Sandor Spisak
    2nd Department of Medicine, Semmelweis University, Budapest, Hungary
    Dis Markers 28:1-14. 2010
    ..Antibody microarrays may have a fundamental importance in testing of marker combinations and future application in diagnostics of tumorous diseases...
  9. doi request reprint Lymphoid aggregates may contribute to the migration and epithelial commitment of bone marrow-derived cells in colonic mucosa
    Gábor Valcz
    2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    J Clin Pathol 64:771-5. 2011
    ..The aim was to study the role of lymphoid aggregates in the migration and transition of BMDCs in both healthy colons and non-specific colitis (NSC)...
  10. doi request reprint Diagnostic mRNA expression patterns of inflamed, benign, and malignant colorectal biopsy specimen and their correlation with peripheral blood results
    Orsolya Galamb
    2nd Department of Medicine, Semmelweis University, Szentkiralyi str 46, 1088 Budapest, Hungary
    Cancer Epidemiol Biomarkers Prev 17:2835-45. 2008
    ..Our aim was to develop diagnostic mRNA expression patterns that may establish the basis of a new molecular biological diagnostic method...
  11. doi request reprint Matrix metalloproteinase-9 expression in the normal mucosa-adenoma-dysplasia-adenocarcinoma sequence of the colon
    Laszlo Herszenyi
    2nd Department of Medicine, Semmelweis University, 1088 Szentkirályi str 46, Budapest, Hungary
    Pathol Oncol Res 14:31-7. 2008
    ..We demonstrate a significantly higher expression of MMP-9 in adenoma with high grade dysplasia-CRC sequence as compared to normal tissue. The over-expression of MMP-9 strongly suggests its association with colorectal carcinogenesis...
  12. pmc Inflammation, adenoma and cancer: objective classification of colon biopsy specimens with gene expression signature
    Orsolya Galamb
    2nd Department of Medicine, Semmelweis University, Budapest, Hungary
    Dis Markers 25:1-16. 2008
    ..Our results provide further insight into the pathophysiological background of colonic diseases. The results set up data warehouse which can be mined further...
  13. ncbi request reprint Evaluation of malignant and benign gastric biopsy specimens by mRNA expression profile and multivariate statistical methods
    Orsolya Galamb
    2nd Department of Internal Medicine, University Semmelweis, Faculty of Medicine, Budapest, Hungary
    Cytometry B Clin Cytom 72:299-309. 2007
    ..mRNA expression array and multivariate statistical analysis of gastric biopsies can yield insight into the molecular biology basis of local alterations, supporting expression-based identification of morphological alterations...
  14. pmc Dysplasia-carcinoma transition specific transcripts in colonic biopsy samples
    Orsolya Galamb
    2nd Department of Medicine, Semmelweis University, Budapest, Hungary
    PLoS ONE 7:e48547. 2012
    ....
  15. doi request reprint The role of the bone marrow derived mesenchymal stem cells in colonic epithelial regeneration
    Gábor Valcz
    2nd Department of Internal Medicine, Cell Analysis Laboratory, Semmelweis University, Szentkiralyi Street 46, 1088 Budapest, Hungary
    Pathol Oncol Res 17:11-6. 2011
    ..In this review we summarize the current information about the role of BM-MSCs in the repair progress of injured colonic epithelium and their potential clinical applications...
  16. ncbi request reprint mRNA expression, functional profiling and multivariate classification of colon biopsy specimen by cDNA overall glass microarray
    Orsolya Galamb
    2nd Department of Internal Medicine, University Semmelweis, Budapest, Hungary
    World J Gastroenterol 12:6998-7006. 2006
    ..To understand the local pathophysiological alterations and gene ontology-based functional classification of colonic biopsies into inflammatory and neoplastic diseases...
  17. ncbi request reprint Potential biomarkers of colorectal adenoma-dysplasia-carcinoma progression: mRNA expression profiling and in situ protein detection on TMAs reveal 15 sequentially upregulated and 2 downregulated genes
    Orsolya Galamb
    2nd Department of Medicine, Semmelweis University, Szentkiralyi str 46, Budapest, Hungary
    Cell Oncol 31:19-29. 2009
    ..As most colorectal cancers (CRC) develop from villous adenomas, studying alterations in gene expression profiles across the colorectal adenoma-dysplasia-carcinoma sequence may yield potential biomarkers of disease progression...
  18. doi request reprint Increased p53 expression in the malignant transformation of Barrett's esophagus is accompanied by an upward shift of the proliferative compartment
    Istvan Hritz
    2nd Dept Medicine, Semmelweis University, 1088, Budapest, Szentkiralyi u 46, Hungary
    Pathol Oncol Res 15:183-92. 2009
    ..Quantification of these parameters in BE is thought to be useful to identify patients at higher risk for progression to adenocarcinoma...
  19. pmc Sporadic colorectal cancer development shows rejuvenescence regarding epithelial proliferation and apoptosis
    Katalin Leiszter
    2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    PLoS ONE 8:e74140. 2013
    ..We also tested the underlying molecular biology concerning the proliferation- and apoptosis-regulating gene expression alterations...
  20. doi request reprint Elevated osteopontin expression and proliferative/apoptotic ratio in the colorectal adenoma-dysplasia-carcinoma sequence
    Gábor Valcz
    2nd Department of Internal Medicine, Semmelweis University, Cell Analysis Laboratory, Szentkiralyi Street 46, 1088 Budapest, Hungary
    Pathol Oncol Res 16:541-5. 2010
    ..The significantly elevated OPN protein levels we found during normal epithelium to carcinoma progression may contribute to the increased fibroblast-myofibroblast transition determining stem cell niche in colorectal cancer...
  21. doi request reprint [Free circulating DNA based colorectal cancer screening from peripheral blood: the possibility of the methylated septin 9 gene marker]
    Kinga Tóth
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 150:969-77. 2009
    ..Nowadays intensive researches are going on about the relation between the septin 9 gene hypermethylation and colorectal cancer development...
  22. pmc Peripheral blood based discrimination of ulcerative colitis and Crohn's disease from non-IBD colitis by genome-wide gene expression profiling
    Ferenc Sipos
    2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    Dis Markers 30:1-17. 2011
    ..Transcriptional profile alterations in peripheral blood can be located in diseased colon...
  23. ncbi request reprint [Appearing of bone marrow derived stem cells in healthy and regenerating colonic epithelium]
    Gábor Valcz
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 150:1852-7. 2009
    ..MSC cells probably leave circulation around lymphoid aggregates to then migrate into nearby crypts. During migration they change their phenotype upon the influence of local microenvironment...
  24. ncbi request reprint Isolation of epsilon-haemoglobin-chain positive fetal cells with micromanipulation for prenatal diagnosis
    Gyula Richard Nagy
    Department of Obstetrics and Gynecology, Semmelweis University, Faculty of Medicine, Budapest, Hungary
    Prenat Diagn 25:398-402. 2005
    ..Here we report our first results...
  25. pmc Association of self-DNA mediated TLR9-related gene, DNA methyltransferase, and cytokeratin protein expression alterations in HT29-cells to DNA fragment length and methylation status
    István Fűri
    2nd Department of Internal Medicine, Semmelweis University, Szentkiralyi Street 46, Budapest 1088, Hungary
    ScientificWorldJournal 2013:293296. 2013
    ..There may be a molecular link between TLR9 signaling and DNMT3A. The mode of self-DNA treatment may influence HT29 cell differentiation. ..
  26. pmc Epithelial toll-like receptor 9 signaling in colorectal inflammation and cancer: clinico-pathogenic aspects
    István Fűri
    2nd Department of Internal Medicine, Semmelweis University, 1088 Budapest, Hungary
    World J Gastroenterol 19:4119-26. 2013
    ..TLR9 agonist DNA-based immunomodulatory sequences could also represent a promising therapeutic alternative in systemic inflammatory conditions and chronic colonic inflammations as their side effects are not significant. ..
  27. ncbi request reprint [Tissue microarray (TMA) validated progression markers in colorectal cancer using antibody microarrays]
    Sandor Spisak
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 150:1607-13. 2009
    ..Using microarray systems, hundreds or thousands of parameters could be examined simultaneously for answering the mentioned questions...
  28. pmc Detection of methylated SEPT9 in plasma is a reliable screening method for both left- and right-sided colon cancers
    Kinga Tóth
    2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    PLoS ONE 7:e46000. 2012
    ..However, its relationship to cancer localization, guaiac-based fecal occult blood test (gFOBT) and carcinoembryonic antigen (CEA) have not been described...
  29. pmc Genome-wide screening of genes regulated by DNA methylation in colon cancer development
    Sandor Spisak
    Molecular Medicine Research Unit, Hungarian Academy of Sciences, Budapest, Hungary
    PLoS ONE 7:e46215. 2012
    ..Activity of these genes possibly interferes with tumor progression, therefore genes identified can be key factors in the formation and in the progression of the disease...
  30. doi request reprint The behavior of matrix metalloproteinase-9 in lymphocytic colitis, collagenous colitis and ulcerative colitis
    Gabor Lakatos
    2nd Department of Medicine, Semmelweis University, Budapest, Hungary
    Pathol Oncol Res 18:85-91. 2012
    ..In contrast, the mucosal up-regulation of MMP-9 correlated with the severity of inflammation in UC. The increased MMP-9 expression could contribute to the severity of mucosal damage in active UC...
  31. pmc Physiological and pathological role of local and immigrating colonic stem cells
    Ferenc Sipos
    Ferenc Sipos, Gábor Valcz, 2nd Department of Internal Medicine, Semmelweis University, 1088 Budapest, Hungary
    World J Gastroenterol 18:295-301. 2012
    ..This paper focuses on stem cell biology in the context of physiological and pathological processes in the human colon...
  32. doi request reprint Helicobacter pylori and antrum erosion-specific gene expression patterns: the discriminative role of CXCL13 and VCAM1 transcripts
    Orsolya Galamb
    2nd Department of Medicine, Semmelweis University, Budapest, Hungary
    Helicobacter 13:112-26. 2008
    ..pylori-positive and H. pylori-negative gastric erosions and adjacent mucosa to explain the possible role and response to H. pylori infection and to get erosion-related mRNA expression patterns...
  33. ncbi request reprint [Changes in the proliferation and apoptosis of colonic epithelial cells in correlation with histologic activity of ulcerative colitis]
    Ferenc Sipos
    Semmelweis Egyetem, Budapest
    Orv Hetil 143:2485-8. 2002
    ..Aim of the study was to compare the rate of epithelial cell apoptosis and proliferation within colonic crypts considering the histological activity of ulcerative colitis...
  34. ncbi request reprint [Insulin-like growth factor receptor, hepatocyte-derived growth factor receptor and telomerase expression in ulcerative colitis]
    Ferenc Sipos
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Magyar Tudományos Akadémia, Budapest
    Orv Hetil 147:1835-41. 2006
    ..Aim of the study was to describe the expression alterations of regenerative signal receptors and cell aging inhibitory systems within colonic crypts considering the histological activity of the disease...
  35. ncbi request reprint MMP3 and CXCL1 are potent stromal protein markers of dysplasia-carcinoma transition in sporadic colorectal cancer
    Ferenc Sipos
    a2nd Department of Internal Medicine bFaculty of Medicine, Department of Medicine c1st Department of Pathology and Experimental Cancer Research, Semmelweis University dMolecular Medicine Research Unit, Hungarian Academy of Sciences, Budapest, Hungary
    Eur J Cancer Prev 23:336-43. 2014
    ....
  36. ncbi request reprint Scanning fluorescent microscopy analysis is applicable for absolute and relative cell frequency determinations
    Jozsef Bocsi
    1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary
    Cytometry A 61:1-8. 2004
    ..Recently, we developed a scanning fluorescent microscopy (SFM) technique. This study compares SFM to LSC (two slide-based cytometry, SBC, techniques) and FCM, in experimental and clinical settings...
  37. ncbi request reprint Laser microdissection in translational and clinical research
    Andras Ladanyi
    Second Department of Medicine, Semmelweis University, Budapest, Hungary
    Cytometry A 69:947-60. 2006
    ..However, understanding the advantages and disadvantages of LMD technology and associated sample preparation procedures may aid in the earlier introduction of this method into the routine clinical diagnostics...
  38. pmc Complete genes may pass from food to human blood
    Sandor Spisak
    Molecular Medicine Research Group, Hungarian Academy of Sciences, Budapest, Hungary
    PLoS ONE 8:e69805. 2013
    ..The plant DNA concentration shows a surprisingly precise log-normal distribution in the plasma samples while non-plasma (cord blood) control sample was found to be free of plant DNA. ..
  39. pmc Regulatory T cells in inflammatory bowel diseases and colorectal cancer
    Gyorgyi Muzes
    2nd Department of Internal Medicine, Semmelweis University, 1088 Budapest, Hungary
    World J Gastroenterol 18:5688-94. 2012
    ..In this paper, we aimed to review the current data surrounding the role of T(regs) in the pathogenesis of IBD, colitis-associated colon cancer and sporadic colorectal cancer...
  40. pmc Elevation in peripheral blood circulating tumor cell number correlates with macroscopic progression in UICC stage IV colorectal cancer patients
    Bela Molnar
    II Department of Medicine, Semmelweis University, 1088 Budapest, Hungary
    Dis Markers 24:141-50. 2008
    ..Results are non-existent for the application of these techniques to the determination of progression and therapy response in Dukes stage D CRC patients...
  41. ncbi request reprint The results of the expression array studies correlate and enhance the known genetic basis of gastric and colorectal cancer
    Orsolya Galamb
    II Department of Medicine, Semmelweis University, Faculty of Medicine Budapest, Hungary
    Cytometry B Clin Cytom 68:1-17. 2005
    ....
  42. ncbi request reprint Molecular pathogenesis of Helicobacter pylori infection: the role of bacterial virulence factors
    Bela Molnar
    Molecular Medicine Research Unit, Semmelweis University and the Hungarian Academy of Sciences, 2nd Department of Medicine, Budapest, Hungary
    Dig Dis 28:604-8. 2010
    ..The possible role of host counter responses and interactions with gastric epithelia and immune cells are also detailed...
  43. ncbi request reprint [Stem cell theory of colorectal cancer and its connection with molecular-biological data]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika, Budapest
    Orv Hetil 148:779-85. 2007
    ..The spread of dysplastic cells (bottom-up, top-down hypothesis) is also ambiguous...
  44. doi request reprint Genome-wide screening for understanding the role of DNA methylation in colorectal cancer
    Ferenc Sipos
    2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    Epigenomics 5:569-81. 2013
    ..By introduction of genome-wide DNA methylation profiling into clinical practice not only the patients' risk stratification but development of targeted therapies will also be possible. ..
  45. ncbi request reprint [Changes in cell kinetics and clinical course in inflammatory bowel diseases]
    Ferenc Sipos
    Általános Orvostudományi Kar, II Belgyógyászati Klinika, Semmelweis Egyetem, Budapest
    Orv Hetil 143:1175-81. 2002
    ..Behind these disturbances which can lead to chronic remitting inflammatory processes the imbalance of apoptosis and proliferation plays a key role...
  46. ncbi request reprint [Necessity of chip technology in stomach cancer]
    Orsolya Galamb
    Semmelweis Egyetem Altalános Orvostudományi Kar, II Belgyógyászati Klinika, MTA Semmelweis Egyetem Gasztroenterológiai és Endokrinológiai Kutató Csoport, Budapest
    Orv Hetil 145:939-47. 2004
    ..All results show connection to and complete the already known molecular background of gastric cancer...
  47. ncbi request reprint [Isolation and therapeutic use of human stem cells]
    Ferenc Sipos
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, MTA SE, Gasztroenterológiai és Endokrinológiai Kutató Csoport
    Orv Hetil 146:1327-33. 2005
    ..The first therapeutic interventions have been already done in diseases such as myocardial infarction or diabetes mellitus, and led to promising results...
  48. pmc Changes of the cytokine profile in inflammatory bowel diseases
    Gyorgyi Muzes
    2nd Department of Internal Medicine, Semmelweis University, 1088 Budapest, Hungary
    World J Gastroenterol 18:5848-61. 2012
    ..The better understanding of their production and functional activity may lead to the development of new therapeutic modalities...
  49. ncbi request reprint Interaction of autophagy and toll-like receptors: a regulatory cross- talk - even in cancer cells?
    Gyorgyi Muzes
    2nd Department of Internal Medicine, Semmelweis University, H 1088 Budapest, Szentkiralyi street 46 Hungary
    Curr Drug Targets 15:743-52. 2014
    ..Upon translation of basic knowledge into practice it is reasonable to speculate that modulation of the TLR-autophagy regulatory loop might be relevant for cancer treatment by providing further possible therapeutic targets. ..
  50. doi request reprint Multicentric Castleman's disease: a challenging diagnosis
    Gyorgyi Muzes
    2nd Department of Medicine, Semmelweis University, 1088 Budapest, Szentkiralyi u 46, Hungary
    Pathol Oncol Res 19:345-51. 2013
    ..To date there are no direct therapeutic evidences, but having been translated to daily practice the main regulatory factors may serve as promising therapeutic targets. ..
  51. pmc Alterations of glutathione S-transferase and matrix metalloproteinase-9 expressions are early events in esophageal carcinogenesis
    Laszlo Herszenyi
    2nd Department of Medicine, Semmelweis University, H 1088 Budapest, Szentkiralyi u 46, Hungary
    World J Gastroenterol 13:676-82. 2007
    ..To investigate the role of glutathione S-transferase (GST) and matrix metalloproteinase-9 (MMP-9) expressions in the development and progression of reflux esophagitis-Barrett's metaplasia-dysplasia-adenocarcinoma sequence in the esophagus...
  52. ncbi request reprint Molecular detection of circulating cancer cells. Role in diagnosis, prognosis and follow-up of colon cancer patients
    Bela Molnar
    Clinical Gastroenterology and Endocrinology Unit, Semmelweis University, Hungarian Academy of Sciences, Budapest, Hungary
    Dig Dis 21:320-5. 2003
    ..The circulating tumor cells of solid tumors, especially in colorectal cancer has been of great interest in medical research in the last and new century...
  53. ncbi request reprint [Possibilities of investigation and clinical application of adult human stem cells]
    Orsolya Galamb
    Semmelweis Egyetem, Általános Orvostudományi Kar, II sz Belgyógyászati Klinika MTA Semmelweis Egyetem Gasztroenterológiai és Endokrinológiai Kutató Csoport, Budapest
    Orv Hetil 144:2263-70. 2003
    ....
  54. ncbi request reprint The half-and-half nail: a new sign of Crohn's disease? Report of four cases
    Tamas Zagoni
    Laboratory of Endoscopy, 2nd Dept of Medicine, Semmelweis University, Szentkiralyi u 46, Budapest 1088, Hungary
    Dis Colon Rectum 49:1071-3. 2006
    ..The relationship of this symptom to clinical activity cannot yet be assessed and has only been observed in four cases...
  55. ncbi request reprint [The importance and use of laser microdissection in clinical research and diagnostic method development]
    Ferenc Sipos
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, MTA Gasztroenterológiai és Endokrinológiai kutatócsoport
    Orv Hetil 145:1355-61. 2004
    ..The aims of this study are to summarize current practical experiences and to foreshow the application possibilities of this quite new technique in clinical practice...
  56. pmc Interplay of autophagy and innate immunity in Crohn's disease: a key immunobiologic feature
    Gyorgyi Muzes
    2nd Department of Internal Medicine, Semmelweis University, 1088 Budapest, Hungary
    World J Gastroenterol 19:4447-54. 2013
    ..In this review, recent advances in the exciting crosstalk of susceptibility coding variants-related autophagy and innate immunity are discussed. ..
  57. pmc Serrated pathway: Alternative route to colorectal cancer
    Arpád V Patai
    Árpád V Patai, Ferenc Sipos, 2 Department of Internal Medicine, Semmelweis University, 1088 Budapest, Hungary
    World J Gastroenterol 19:607-15. 2013
    ..In this review we would like to highlight morphological, molecular and clinical features of this emerging pathway that are essential for gastroenterologists and may influence their everyday practice...
  58. ncbi request reprint Carcinoma arising in enterocutan fistulae of Crohn's disease patients: description of two cases
    Tamas Zagoni
    2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    Int J Colorectal Dis 21:461-4. 2006
    ..We reported two cases of fistula cancers treated with infliximab. The short time-span between the administration of this drug and the diagnosis of cancer makes the correlation between the two unlikely...
  59. ncbi request reprint Scanning fluorescent microscopy is an alternative for quantitative fluorescent cell analysis
    Viktor Sebestyen Varga
    Hungarian Academy of Sciences, Clinical Gastroenterology Research Unit, Budapest, Hungary
    Cytometry A 60:53-62. 2004
    ....
  60. pmc Anti-tumor immunity, autophagy and chemotherapy
    Gyorgyi Muzes
    2nd Department of Internal Medicine, Semmelweis University, 1088 Budapest, Hungary
    World J Gastroenterol 18:6537-40. 2012
    ..Relation of autophagy to anticancer immune responses may indicate a novel aspect in cancer chemotherapy...
  61. doi request reprint Successful tocilizumab treatment in a patient with human herpesvirus 8-positive and human immunodeficiency virus-negative multicentric Castleman's disease of plasma cell type nonresponsive to rituximab-CVP therapy
    Gyorgyi Muzes
    2nd Department of Medicine, Semmelweis University, Budapest, Hungary
    APMIS 121:668-74. 2013
    ..The patient is still receiving tocilizumab. This case emphasizes the individual nature of MCD requiering more personalized disease management...
  62. pmc Effect of ageing on colonic mucosal regeneration
    Ferenc Sipos
    Ferenc Sipos, Katalin Leiszter, 2nd Department of Internal Medicine, Semmelweis University, 1088 Budapest, Hungary
    World J Gastroenterol 17:2981-6. 2011
    ..Here, we aim to summarize the age-related microscopic and molecular changes of the human colon, as well as their role in altered mucosal healing...
  63. ncbi request reprint [First attempts of detecting fetal cells in the maternal circulation]
    Gyula Richard Nagy
    Semmelweis Egyetem, Általános Orvostudományi Kar, I Szülészeti és Nogyógyászati Klinika, Budapest
    Orv Hetil 145:2231-6. 2004
    ..In prenatal diagnosis there is great interest for noninvasive diagnostic methods. Authors report their first results in detecting fetal cells in the maternal circulation during pregnancy...
  64. pmc Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon
    Ferenc Sipos
    Ferenc Sipos, Cell Analysis Laboratory, 2nd Department of Internal Medicine, Semmelweis University, 1088 Budapest, Hungary
    World J Gastroenterol 18:601-8. 2012
    ..The preliminary results of the current studies are promising, but more clinical investigations are needed to develop new and safe therapeutic strategies for diseases of the colon...
  65. ncbi request reprint [Identification of colorectal cancer, adenoma, and inflammatory bowel disease specific gene expression patterns using whole genomic oligonucleotide microarray system]
    Orsolya Galamb
    Semmelweis Egyetem, Általános Orvostudományi Kar II Belgyógyászati Klinika Budapest
    Orv Hetil 148:2067-79. 2007
    ....
  66. doi request reprint [Functional mRNA expression analysis and classification of colonic biopsy samples using overall cDNA microarray technique]
    Orsolya Galamb
    Semmelweis Egyetem, Általános Orvostudományi Kar II Belgyógyászati Klinika Budapest
    Orv Hetil 149:219-32. 2008
    ....
  67. ncbi request reprint [Theoretical foundations of protein chips and their possible use in medical research and diagnostics]
    Sandor Spisak
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika, MTA SE Molekuláris Medicina Kutatócsoport Budapest
    Orv Hetil 148:1511-20. 2007
    ....
  68. ncbi request reprint Identification and validation of colorectal neoplasia-specific methylation markers for accurate classification of disease
    Fabian Model
    Epigenomics, Inc, Suite 300, 1000 Seneca Street, Seattle, WA 98101, USA
    Mol Cancer Res 5:153-63. 2007
    ....