Zsofia Nemoda

Summary

Affiliation: Semmelweis University
Country: Hungary

Publications

  1. pmc Assessing genetic polymorphisms using DNA extracted from cells present in saliva samples
    Zsofia Nemoda
    Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Tuzolto utca, Budapest, Hungary
    BMC Med Res Methodol 11:170. 2011
  2. pmc Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood
    Zsofia Nemoda
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Neurosci Biobehav Rev 35:1665-86. 2011
  3. pmc Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients
    Zsofia Nemoda
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Behav Brain Funct 6:4. 2010
  4. doi request reprint Carboxylesterase 1 gene polymorphism and methylphenidate response in ADHD
    Zsofia Nemoda
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Neuropharmacology 57:731-3. 2009
  5. doi request reprint Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children
    Eva Kereszturi
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 147:1431-5. 2008
  6. ncbi request reprint Analysis of a polymorphic microRNA target site in the purinergic receptor P2RX7 gene
    Omar Abdul Rahman
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Electrophoresis 31:1790-5. 2010
  7. ncbi request reprint Dopaminergic candidate genes in Tourette syndrome: association between tic severity and 3' UTR polymorphism of the dopamine transporter gene
    Zsanett Tarnok
    Vadaskert Child and Adolescent Psychiatric Clinic, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 144:900-5. 2007
  8. ncbi request reprint Association between the 120-bp duplication of the dopamine D4 receptor gene and attention deficit hyperactivity disorder: genetic and molecular analyses
    Eva Kereszturi
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 144:231-6. 2007
  9. doi request reprint P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients
    Geza Nagy
    Semmelweis University, 2nd Department of Internal Medicine, Budapest, 1088, Szentkiralyi u 46, Hungary
    Prog Neuropsychopharmacol Biol Psychiatry 32:1884-8. 2008
  10. doi request reprint Associations between depression severity and purinergic receptor P2RX7 gene polymorphisms
    Zsuzsa Halmai
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
    J Affect Disord 150:104-9. 2013

Collaborators

Detail Information

Publications17

  1. pmc Assessing genetic polymorphisms using DNA extracted from cells present in saliva samples
    Zsofia Nemoda
    Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Tuzolto utca, Budapest, Hungary
    BMC Med Res Methodol 11:170. 2011
    ..In five studies we document the effects of sample volume, handling and storage conditions, type of collection device, and oral sampling location, on quantity, quality, and genetic assessment of DNA extracted from cells present in saliva...
  2. pmc Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood
    Zsofia Nemoda
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Neurosci Biobehav Rev 35:1665-86. 2011
    ..The dopamine catabolizing enzyme genes, such as monoamine oxidase (MAO) A and catechol-O-methyltransferase (COMT) genes, have been linked to aggressive behaviors...
  3. pmc Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients
    Zsofia Nemoda
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Behav Brain Funct 6:4. 2010
    ..However, the efficacy of dopamine D2 receptor (DRD2) blocking antipsychotic drugs in BPD treatment also suggests involvement of the dopamine system in the neurobiology of BPD...
  4. doi request reprint Carboxylesterase 1 gene polymorphism and methylphenidate response in ADHD
    Zsofia Nemoda
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Neuropharmacology 57:731-3. 2009
    ..410 +/- 0.127 vs 0.572 +/- 0.153 mg/kg, t(1,88) = 2.33, p = 0.022). This result warrants for further investigations of the CES1 gene in larger ADHD samples...
  5. doi request reprint Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children
    Eva Kereszturi
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 147:1431-5. 2008
    ..015). This interaction might reflect the regulatory effect of COMT dominated prefrontal dopamine transmission on subcortical dopamine systems, which are the actual site of methylphenidate action...
  6. ncbi request reprint Analysis of a polymorphic microRNA target site in the purinergic receptor P2RX7 gene
    Omar Abdul Rahman
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Electrophoresis 31:1790-5. 2010
    ..The developed genotyping method was applied in our depression-related association study...
  7. ncbi request reprint Dopaminergic candidate genes in Tourette syndrome: association between tic severity and 3' UTR polymorphism of the dopamine transporter gene
    Zsanett Tarnok
    Vadaskert Child and Adolescent Psychiatric Clinic, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 144:900-5. 2007
    ..002). In summary, allele frequencies did not differ between cases and controls, but DAT1 genotype accounted for variations of tic severity within the TS group...
  8. ncbi request reprint Association between the 120-bp duplication of the dopamine D4 receptor gene and attention deficit hyperactivity disorder: genetic and molecular analyses
    Eva Kereszturi
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 144:231-6. 2007
    ..These results suggest that the 1-repeat form of the 120-bp dup might be a risk factor of ADHD, especially in the homozygous form and/or in the context of certain haplotypes...
  9. doi request reprint P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients
    Geza Nagy
    Semmelweis University, 2nd Department of Internal Medicine, Budapest, 1088, Szentkiralyi u 46, Hungary
    Prog Neuropsychopharmacol Biol Psychiatry 32:1884-8. 2008
    ..We assumed that genetic influence would be stronger on depressive symptoms in the "poor glycemic control" group (PC: HbA1C>7%) compared to the "good glycemic control" group (GC: HbA1C<or=7%)...
  10. doi request reprint Associations between depression severity and purinergic receptor P2RX7 gene polymorphisms
    Zsuzsa Halmai
    Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
    J Affect Disord 150:104-9. 2013
    ..In the current study the genetic effects of rs2230912 (Gln460Arg) and rs1653625 (located in the 3' untranslated region of the P2RX7 gene) were explored in mood disorders...
  11. ncbi request reprint Association between depression and the Gln460Arg polymorphism of P2RX7 gene: a dimensional approach
    Krisztina Hejjas
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 150:295-9. 2009
    ..In conclusion, case-control analysis did not reveal significant results, but using a symptom severity scale we could support the association between depressive disorder and the G-allele of the Gln460Arg polymorphism in the P2RX7 gene...
  12. doi request reprint Additive effects of serotonergic and dopaminergic polymorphisms on trait impulsivity
    Gabor Varga
    Institute of Psychology, Eotvos Lorand University, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 159:281-8. 2012
    ..These results clearly suggest an additive effect of dopaminergic and serotonergic polymorphisms on trait impulsivity...
  13. pmc Infant genotype may moderate sensitivity to maternal affective communications: attachment disorganization, quality of care, and the DRD4 polymorphism
    Judit Gervai
    Institute for Psychology, Hungarian Academy of Sciences, Budapest, Hungary
    Soc Neurosci 2:307-19. 2007
    ..Among carriers of the 7-repeat DRD4 allele, there was no relation between quality of maternal communication and infant disorganization. This interaction effect was independent of degree of social risk and maternal DRD4 genotype...
  14. ncbi request reprint Linkage analysis and molecular haplotyping of the dopamine D4 receptor gene promoter region
    Eszter Szantai
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, POB 260, Hungary 1444
    Psychiatr Genet 15:259-70. 2005
    ..Besides the accurate phenotype characterization, highly reliable genotyping methods are also of outstanding importance in these works...
  15. ncbi request reprint [Analysis of the dopamine D4 receptor gene variants in attention deficit hyperactivity disorder]
    Eva Kereszturi
    Semmelweis Egyetem, Orvosi Vegytani, Molekuláris Biológiai és Pathobiokémiai Intézet, Budapest
    Neuropsychopharmacol Hung 9:11-8. 2007
    ..01). These results of association and functional analyses suggest that the 1-repeat form of the 120 bp duplication might be a risk factor of ADHD...
  16. ncbi request reprint Direct haplotype detection of adjacent polymorphic sites in the regulatory region of the dopamine D4 receptor (DRD4) gene
    Zsolt Ronai
    Institute of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary
    Electrophoresis 23:1512-6. 2002
    ..We have also demonstrated that the haplotypes of double heterozygotes for -521 C/T and for the 120 bp duplication can be clearly distinguished, that has only been possible previously by extensive pedigree analysis...
  17. ncbi request reprint [Genetic factors in obsessive-compulsive disorder: summary of genetic studies]
    Eszter Kenézloi
    Vadaskert Gyermekpszichiátriai Kóház és Szakambulancia, Budapest, Hungary
    Psychiatr Hung 25:378-93. 2010
    ..After an overview of the applied genetic methods, we will summarize the genetic results of the OCD literature, especially candidate gene association studies. Finally, we will outline the possible future trends in psychiatric genetics...