Krisztina Hagymasi

Summary

Affiliation: Semmelweis University
Country: Hungary

Publications

  1. doi request reprint [Review of overlap syndromes in autoimmune liver diseases. Diagnostic and therapeutic difficulties]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 154:923-9. 2013
  2. ncbi request reprint [Stem cell theory of colorectal cancer and its connection with molecular-biological data]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika, Budapest
    Orv Hetil 148:779-85. 2007
  3. ncbi request reprint [Genetic background of multifactorial liver and bile duct diseases]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika Budapest Szentkirályi u 46
    Orv Hetil 148:147-53. 2007
  4. ncbi request reprint [Inflammatory bowel disease and colorectal cancer]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 147:1977-82. 2006
  5. ncbi request reprint [Genetic background of irritable bowel syndrome]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 147:1167-70. 2006
  6. ncbi request reprint [The genetics of obesity]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 147:107-13. 2006
  7. ncbi request reprint [The Human Genome Project, genetic viability and genetic epidemiology]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 146:2575-80. 2005
  8. doi request reprint [Role of the endocrine system in the pathogenesis of non-alcoholic fatty liver disease]
    Krisztina Hagymasi
    Belgyógyászati Klinika Budapest, Budapest
    Orv Hetil 150:2173-81. 2009
  9. doi request reprint [Risk factors for esophageal cancer, and possible genetic background]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika Budapest Szentkirályi u 46 1088 Magyar Tudományos Akadémia Molekuláris Medicina Kutatócsoport Budapest
    Orv Hetil 150:407-13. 2009
  10. doi request reprint [Peptic ulcer: facts and questions -- 2010]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika, Budapest
    Orv Hetil 151:1054-61. 2010

Collaborators

Detail Information

Publications36

  1. doi request reprint [Review of overlap syndromes in autoimmune liver diseases. Diagnostic and therapeutic difficulties]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 154:923-9. 2013
    ..Treatment depends on the predominant feature of the overlap syndrome; ursodeoxycholic acid and/or immunsuppressive (corticosteroid) treatment are used, based on observations from retrospective, non-randomized studies...
  2. ncbi request reprint [Stem cell theory of colorectal cancer and its connection with molecular-biological data]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika, Budapest
    Orv Hetil 148:779-85. 2007
    ..The spread of dysplastic cells (bottom-up, top-down hypothesis) is also ambiguous...
  3. ncbi request reprint [Genetic background of multifactorial liver and bile duct diseases]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika Budapest Szentkirályi u 46
    Orv Hetil 148:147-53. 2007
    ..In the future, the genetic background may permit prevention, early, accurate diagnosis, prediction of disease course, complications, prognosis, as well as treatment response...
  4. ncbi request reprint [Inflammatory bowel disease and colorectal cancer]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 147:1977-82. 2006
    ..Meta-analysis showed efficacy of mesalamine in the reduction of risk of colorectal cancer, but prospective trials have been missed. Chemoprotective role of other immunomodulators has not been proven yet...
  5. ncbi request reprint [Genetic background of irritable bowel syndrome]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 147:1167-70. 2006
    ..Firm conclusions about the role of serotonin system, as well as other neuroreceptors, G-proteins, cytokine polymorphisms in the pathogenesis of IBS cannot be made...
  6. ncbi request reprint [The genetics of obesity]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 147:107-13. 2006
    ..Identification of the genetic background of the obesity will help to understand the exact molecular mechanism of the pathogenesis, make possible the prevention, as well as individual therapeutic interventions...
  7. ncbi request reprint [The Human Genome Project, genetic viability and genetic epidemiology]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 146:2575-80. 2005
    ..The knowledge of human genome and application of multiple biomarkers will improve our ability to identify individuals at risk, so that preventive interventions can be applied, earlier diagnosis can be made and treatment can be optimized...
  8. doi request reprint [Role of the endocrine system in the pathogenesis of non-alcoholic fatty liver disease]
    Krisztina Hagymasi
    Belgyógyászati Klinika Budapest, Budapest
    Orv Hetil 150:2173-81. 2009
    ..The alterations of endocrine system must be considered in the background of cryptogenic liver diseases. The endocrine perspective may help the therapeutic approaches in the future...
  9. doi request reprint [Risk factors for esophageal cancer, and possible genetic background]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika Budapest Szentkirályi u 46 1088 Magyar Tudományos Akadémia Molekuláris Medicina Kutatócsoport Budapest
    Orv Hetil 150:407-13. 2009
    ..Understanding the exact pathogenesis can help the prevention of this highly aggressive cancer, with the use of natural substances and nonsteroid inflammatory drugs...
  10. doi request reprint [Peptic ulcer: facts and questions -- 2010]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika, Budapest
    Orv Hetil 151:1054-61. 2010
    ..The number of Helicobacter pylori and NSAID negative ulcers is likely to increase, their therapy must be clarified. There's a fall in the eradication rate of Helicobacter pylori infection, the optimal treatment is missing...
  11. doi request reprint [Non-alcoholic steatosis/steatohepatitis -- 2010]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar II Belgyógyászati Klinika Budapest Szentkirályi u 46 1088
    Orv Hetil 151:1940-5. 2010
    ..There is no proven specific therapy; the aim is the elimination of provoking factors (weight loss), treatment of diabetes mellitus and hyperlipidemia. Besides, liver protection (antioxidants) is important, as well...
  12. doi request reprint [Tomato peel: rare cause of biliary tract obstruction]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar II Belgyógyászati Klinika Budapest Szentkirályi u 46 1088
    Orv Hetil 152:1907-10. 2011
    ..Authors summarize the medical history of a 91-year-old female patient, who developed vomiting and right subcostal pain due to the presence of tomato peel within the ductus choledochus...
  13. doi request reprint Update on the pharmacogenomics of proton pump inhibitors
    Krisztina Hagymasi
    Semmelweis University, II Department of Internal Medicine, 1088 Budapest, Szentkiralyi u 46, Hungary
    Pharmacogenomics 12:873-88. 2011
    ....
  14. doi request reprint Lymphoid aggregates may contribute to the migration and epithelial commitment of bone marrow-derived cells in colonic mucosa
    Gábor Valcz
    2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary
    J Clin Pathol 64:771-5. 2011
    ..The aim was to study the role of lymphoid aggregates in the migration and transition of BMDCs in both healthy colons and non-specific colitis (NSC)...
  15. ncbi request reprint [Redox homeostasis in inflammatory bowel diseases]
    Anna Blazovics
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 145:1459-66. 2004
    ..It seems that nutritional supplementation and adequate therapy restore the ion homeostasis, although, Zn overdose may cause disturbance in iron metabolism and consequently may influence erythrocyte functions...
  16. ncbi request reprint [Cytokines, prostaglandins, nutritive and non-nuitritive factors in inflammatory bowel diseases]
    Anna Blazovics
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 145:2523-9. 2004
    ..The moderate nutritional customs with natural antioxidants can help restore to normal function of gastrointestinal tract, but the immoderate consumption of vitamins and polyphenol type antioxidant molecules is contraindicated...
  17. ncbi request reprint [Alopecia areata caused by extreme solar abuse]
    Mária Cserhalmi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 147:1573-7. 2006
    ..The main forms and risk factors of UV-radiation, skin damages by UV-light as well as the pathogenesis of the alopecia areata are reviewed...
  18. ncbi request reprint [Investigation of redox homeostasis of liver in experimental and human studies]
    Krisztina Hagymasi
    Semmelweis Egyetem Budapest, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest, Szentkirályi u 46 1088
    Acta Pharm Hung 74:51-63. 2004
    ..The chemiluminometric measurements in erythrocytes is suitable for the estimation of progression of alcoholic liver disease and of efficacy of antioxidant therapy...
  19. ncbi request reprint [Genetics of primary biliary cirrhosis]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 146:2151-5. 2005
    ..Correlation the PBC with polymorphisms of HLA class I, II, III alleles, genes encoding for molecules influencing immune tolerance, apoptosis, cytokine expression, will require additional studies...
  20. ncbi request reprint Silymarin and vitamin E reduce amiodarone-induced lysosomal phospholipidosis in rats
    Márta Agoston
    School of Medicine, Semmelweis University, Szentkiralyi u 46, 1088 Budapest, Hungary
    Toxicology 190:231-41. 2003
    ..Thus, both antioxidant action and inhibition of tissue uptake of amiodarone might have an important role in the preventative effect of antioxidants against amiodarone toxicity...
  21. ncbi request reprint [Role of obesity in colorectal carcinogenesis]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika, Magyar Tudományos Akadémia Molekuláris Medicina Kutatócsoport Budapest Szentkirályi u 46 1088
    Orv Hetil 148:2411-6. 2007
    ..They summarize the role of inflammation, hyperinsulinemia, insulin-like growth factor-I and adipokines in the colorectal carcinogenesis...
  22. ncbi request reprint [Genotype-phenotype associations in inflammatory bowel disease]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 146:1767-73. 2005
    ..In the future, such sheme may permit early, accurate diagnosis, prediction of disease course, complications, prognosis, as well as treatment response...
  23. doi request reprint [Influence of weight reduction on the effectiveness of combined peginterferon and ribavirin treatment in chronic HCV hepatitis]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest, Szentkirályi u 46 1088
    Orv Hetil 149:2189-92. 2008
    ..The obesity is an independent negative predictive factor of inefficacy of antiviral treatment...
  24. doi request reprint [New possibilities of targeted therapy in the treatment of hepatocellular carcinoma with the help of molecular biology]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar II Belgyógyászati Klinika Budapest
    Orv Hetil 151:1763-8. 2010
    ..Alteration of Wnt pathway, retinoid compounds, inhibition of the cell cycle as well as the proteosome, and epigenetic therapy can be other potential promising targets in HCC...
  25. ncbi request reprint [Non-alcoholic steatosis/steatohepatitis]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 146:1494-5. 2005
  26. ncbi request reprint [Genetic background of esophageal squamous cell carcinoma]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar II Belgyógyászati Klinika Budapest Szentkirályi u 46 1088
    Orv Hetil 148:1795-800. 2007
    ..Different targets include complementary nucleic acid treatment (antisense therapy), gene-replacement and importance of small interfering RNA-s...
  27. doi request reprint [Epidemiology, risk factors and molecular pathogenesis of primary liver cancer]
    Krisztina Hagymasi
    Semmelweis Egyetem, Budapest
    Orv Hetil 149:541-8. 2008
    ..Understanding the molecular mechanisms could improve the screening of patients with chronic liver disease, or cirrhosis, and the prevention as well as treatment of hepatocellular carcinoma...
  28. doi request reprint [Data for the decrease of "voluntary childlessness" in inflammatory bowel disease]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar II Belgyógyászati Klinika Budapest
    Orv Hetil 153:1855-62. 2012
    ..Authors review the issues related to fertility, outcome of pregnancy, medical treatment options before and during pregnancy as well as during breastfeeding in inflammatory bowel disease...
  29. ncbi request reprint [Free radical scavenger and lipid peroxidation inhibiting effects of medicinal plants used in phytotherapy]
    Agnes Kery
    Semmelweis Egyetem, Farmakognózia Intézet, Budapest, Ulloi fit 26 1085
    Acta Pharm Hung 74:158-65. 2004
    ..With the use of these results planning and execution of in vivo examinations should be more precise, practical and essential...
  30. ncbi request reprint [Treatment of non-alcoholic steatohepatitis]
    Janos Feher
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 145:631-4. 2004
  31. doi request reprint [Appearing of bone marrow derived stem cells in healthy and regenerating colonic epithelium]
    Gábor Valcz
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 150:1852-7. 2009
    ..Samples from normal healthy individuals and from aspecific inflammation were used. The possible role of lymphoid aggregates in the epithelial regeneration was also studied...
  32. ncbi request reprint [Antioxidants in liver protection]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 145:1421-5. 2004
    ..Beside their antioxidant property they may also directly regulate many important processes, e.g. cell cycle. We have some favourable results with regard combined antioxidant therapy of liver disease of different etiology...
  33. doi request reprint [Idiopathic retroperitoneal fibrosis. Pitfalls and challenges--experience with two cases]
    Hajnal Székely
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest, Szentkirályi u 46 1088
    Orv Hetil 152:1818-26. 2011
    ..Predicting factors for treatment response, corticosteroid demand or relapse are not known. Authors review the medical history of two patients with retroperitoneal fibrosis and discuss diagnostic difficulties of this disorder...
  34. doi request reprint [The new aspects of the eradication of Helicobacter pylori and the importance of bacterial resistance]
    Krisztina Hagymasi
    Semmelweis Egyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika, Budapest
    Orv Hetil 149:2029-35. 2008
    ..A possible solution is the application of sequential therapy, or using newer antibiotics (levofloxacin). The importance of new natural substances (lactoferrin, probiotics, plant drugs) must be further investigated...
  35. doi request reprint [Stem cell transplantation in the treatment of gastrointestinal diseases]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar II Belgyógyászati Klinika Budapest
    Orv Hetil 149:1449-55. 2008
    ..Well-designed, multicentric, prospective studies are needed to confirm the results of case reports and clinical studies with small group of patients...
  36. ncbi request reprint [Gene therapy in pancreatic cancer]
    Krisztina Hagymasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
    Orv Hetil 145:211-5. 2004
    ..Different targets include antisense strategies, gene-replacement, gene-directed prodrug activation therapy, promoter gene strategies, as well as oncolytic viruses...