Istvan Bitter

Summary

Affiliation: Semmelweis University
Country: Hungary

Publications

  1. ncbi request reprint Effectiveness of clozapine, olanzapine, quetiapine, risperidone, and haloperidol monotherapy in reducing hostile and aggressive behavior in outpatients treated for schizophrenia: a prospective naturalistic study (IC-SOHO)
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Balassa u 6, 1083 Budapest, Hungary
    Eur Psychiatry 20:403-8. 2005
  2. pmc Relating the shape of protein binding sites to binding affinity profiles: is there an association?
    Zoltán Simon
    Department of Biochemistry, Institute of Biology, Eotvos Lorand University, Pazmany Peter setany 1 C, H 1117 Budapest, Hungary
    BMC Struct Biol 10:32. 2010
  3. ncbi request reprint Olanzapine versus clozapine in treatment-resistant or treatment-intolerant schizophrenia
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Prog Neuropsychopharmacol Biol Psychiatry 28:173-80. 2004
  4. ncbi request reprint [Current pharmacotherapy of schizophrenia]
    Istvan Bitter
    Semmelweis Egyetem, Általános Orvostudományi Kar, Pszichiatriai es Pszichoterapias Klinika
    Orv Hetil 145:105-9. 2004
  5. ncbi request reprint [Treatment of schizophrenia]
    Istvan Bitter
    Semmelweis Egyetem, Általános Orvostudományi Kar, Pszichiatriai es Pszichoterapias Klinika, Budapest
    Orv Hetil 145:1281-3. 2004
  6. ncbi request reprint Antipsychotic treatment and sexual functioning in first-time neuroleptic-treated schizophrenic patients
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Int Clin Psychopharmacol 20:19-21. 2005
  7. ncbi request reprint [Antipsychotic treatment and metabolic syndrome. Consensus meeting of the Metabolic Working Group of the Hungarian Diabetes Society and the Hungarian Psychiatric Collegium]
    Istvan Bitter
    Semmelweis Egyetem, Pszichiatriai es Pszichoterapias Klinika Balassa u 6, Budapest 1083, Hungary
    Psychiatr Hung 20:312-5. 2005
  8. doi request reprint Adverse reactions to duloxetine in depression
    Istvan Bitter
    Semmelweis University, Department of Psychiatry and Psychotherapy, Budapest, Hungary
    Expert Opin Drug Saf 10:839-50. 2011
  9. ncbi request reprint [Learning cognitive skills in depression: the effect of context-change]
    Patrícia Polgár
    Semmelweis Egyetem, Pszichiatriai es Pszichoterapias Klinika, Budapest, Hungary
    Psychiatr Hung 22:271-5. 2007
  10. doi request reprint Associative learning in deficit and nondeficit schizophrenia
    Márta Farkas
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Neuroreport 19:55-8. 2008

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Effectiveness of clozapine, olanzapine, quetiapine, risperidone, and haloperidol monotherapy in reducing hostile and aggressive behavior in outpatients treated for schizophrenia: a prospective naturalistic study (IC-SOHO)
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Balassa u 6, 1083 Budapest, Hungary
    Eur Psychiatry 20:403-8. 2005
    ..Antipsychotic medications may reduce hostile and aggressive behavior in schizophrenia. This study compared the effectiveness of antipsychotics in the treatment of aggression...
  2. pmc Relating the shape of protein binding sites to binding affinity profiles: is there an association?
    Zoltán Simon
    Department of Biochemistry, Institute of Biology, Eotvos Lorand University, Pazmany Peter setany 1 C, H 1117 Budapest, Hungary
    BMC Struct Biol 10:32. 2010
    ....
  3. ncbi request reprint Olanzapine versus clozapine in treatment-resistant or treatment-intolerant schizophrenia
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Prog Neuropsychopharmacol Biol Psychiatry 28:173-80. 2004
    ..Olanzapine therefore presents a safe alternative in the treatment of refractory schizophrenia...
  4. ncbi request reprint [Current pharmacotherapy of schizophrenia]
    Istvan Bitter
    Semmelweis Egyetem, Általános Orvostudományi Kar, Pszichiatriai es Pszichoterapias Klinika
    Orv Hetil 145:105-9. 2004
    ..Their use is limited by the availability of different formulations, by the lack of experience of some physicians, however the main limitation is the economic barrier...
  5. ncbi request reprint [Treatment of schizophrenia]
    Istvan Bitter
    Semmelweis Egyetem, Általános Orvostudományi Kar, Pszichiatriai es Pszichoterapias Klinika, Budapest
    Orv Hetil 145:1281-3. 2004
  6. ncbi request reprint Antipsychotic treatment and sexual functioning in first-time neuroleptic-treated schizophrenic patients
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Int Clin Psychopharmacol 20:19-21. 2005
    ..There were no significant differences between males and females. Many recent onset patients appear to suffer from problems of sexual functioning. Olanzapine may offer an advantage in this area...
  7. ncbi request reprint [Antipsychotic treatment and metabolic syndrome. Consensus meeting of the Metabolic Working Group of the Hungarian Diabetes Society and the Hungarian Psychiatric Collegium]
    Istvan Bitter
    Semmelweis Egyetem, Pszichiatriai es Pszichoterapias Klinika Balassa u 6, Budapest 1083, Hungary
    Psychiatr Hung 20:312-5. 2005
  8. doi request reprint Adverse reactions to duloxetine in depression
    Istvan Bitter
    Semmelweis University, Department of Psychiatry and Psychotherapy, Budapest, Hungary
    Expert Opin Drug Saf 10:839-50. 2011
    ..This review summarizes the frequency and severity of adverse events observed during the treatment of depression with duloxetine and considers their relevance to clinical practice...
  9. ncbi request reprint [Learning cognitive skills in depression: the effect of context-change]
    Patrícia Polgár
    Semmelweis Egyetem, Pszichiatriai es Pszichoterapias Klinika, Budapest, Hungary
    Psychiatr Hung 22:271-5. 2007
    ..While cognitive functions have been widely studied, much less is known about implicit learning in depression...
  10. doi request reprint Associative learning in deficit and nondeficit schizophrenia
    Márta Farkas
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Neuroreport 19:55-8. 2008
    ..These results suggest that the enduring negative symptoms of deficit patients may be related to decreased response to cognitive feedback and deficient basal ganglia functioning...
  11. doi request reprint General and domain-specific neurocognitive impairments in deficit and non-deficit schizophrenia
    János M Réthelyi
    Department of Psychiatry and Psychotherapy, Semmelweis University, 1083, Budapest, Balassa u 6, Hungary
    Eur Arch Psychiatry Clin Neurosci 262:107-15. 2012
    ..However, our results indicate that cognitive flexibility is specifically impaired in deficit versus non-deficit patients and may therefore represent a core feature of this subtype...
  12. pmc Patients' preference for olanzapine orodispersible tablet compared with conventional oral tablet in a multinational, randomized, crossover study
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    World J Biol Psychiatry 11:894-903. 2010
    ..The aim of this study was to compare patients' preference for olanzapine orodispersible tablet (ODT) with oral conventional tablet (OCT)...
  13. doi request reprint How do different diagnostic criteria, age and gender affect the prevalence of attention deficit hyperactivity disorder in adults? An epidemiological study in a Hungarian community sample
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University Budapest, Balassa u 6, 1083, Budapest, Hungary
    Eur Arch Psychiatry Clin Neurosci 260:287-96. 2010
    ..02% in the < or =40 years age group and 0.70% in the >40 years age group, based on DSM-IV diagnostic criteria. Prevalence rates found in this study are somewhat lower, but still are in line with those reported in the literature...
  14. doi request reprint Prevalence and correlates of adult attention-deficit hyperactivity disorder: meta-analysis
    Viktoria Simon
    Semmelweis University Budapest, Department of Psychiatry and Psychotherapy, Balassa u 6, Budapest H 1083, Hungary
    Br J Psychiatry 194:204-11. 2009
    ..In spite of the growing literature about adult attention-deficit hyperactivity disorder (ADHD), relatively little is known about the prevalence and correlates of this disorder...
  15. doi request reprint The birth of convulsive therapy revisited: a reappraisal of László Meduna's first cohort of patients
    Brigitta Baran
    Department of Psychiatry and Psychotherapy, Faculty of Medicine, Semmelweis University, and Consultation Liaison Psychiatric Service, Szent István and Szent László Hospitals, Budapest, Hungary
    J Affect Disord 136:1179-82. 2012
    ..The introduction of convulsive therapy (COT) was undoubtedly one of the milestones in the history of psychiatry. Its originator, László Meduna, has become one of the founding fathers of biological psychiatry...
  16. ncbi request reprint [Switching patients with schizophrenia to ziprasidone from conventional or other atypical antipsychotics]
    György Bartkó
    Jahn Ferenc Dél pesti Psychiatric Hospital, Budapest, Hungary
    Neuropsychopharmacol Hung 8:201-9. 2006
    ....
  17. ncbi request reprint [Antipsychotic drug combinations in the treatment of schizophrenia. A review of the literature]
    Gabor Gazdag
    Egyesített Szent István es Szent László Kórház Rendelointézet, Addiktologiai es Pszichiatriai Ambulancia, Budapest, Hungary
    Neuropsychopharmacol Hung 14:189-95. 2012
    ..Authors, after reviewing existing scientific data, make attempt to give recommendations for combined antipsychotic therapy in everyday clinical practice...
  18. ncbi request reprint [Neuropsychological impairments in adult attention deficit hyperactivity disorder: a literature review]
    Sára Bálint
    Semmelweis Egyetem, Pszichiatriai es Pszichoterapias Klinika
    Psychiatr Hung 23:324-35. 2008
    ..Attention Deficit Hyperactivity Disorder (ADHD) is one of the most frequently diagnosed childhood psychiatric disorders. Based on various empirical estimates, symptoms of ADHD persist into adulthood in about 30-50% of the childhood cases...
  19. ncbi request reprint [Recent advances in the genetics of schizophrenia and the practical implications of the results]
    Janos Rethelyi
    Semmelweis Egyetem, Pszichiatriai es Pszichoterapias Klinika, Budapest
    Psychiatr Hung 23:152-65. 2008
    ..Synthesis of data from the different areas allows speculation about future research and practical implications...
  20. doi request reprint The beginnings of modern psychiatric treatment in Europe. Lessons from an early account of convulsive therapy
    Brigitta Baran
    Dept of Psychiatry and Psychotherapy, Faculty of Medicine, Semmelweis University, Budapest, Hungary
    Eur Arch Psychiatry Clin Neurosci 258:434-40. 2008
    ..This historical case is discussed from both the diagnostic and therapeutic points of view, and an attempt is made to explain the possible reasons for the discrepancies found between Meduna's account and ZL's case notes...
  21. ncbi request reprint [Pharmacotherapy of adult Attention Deficit/Hyperactivity Disorder (ADHD): a systematic review]
    Agnes Mészáros
    Semmelweis Egyetem, Pszichiatriai es Pszichoterapias Klinika, Budapest, Hungary
    Psychiatr Hung 22:259-70. 2007
    ..The aim of the article was to provide a systematic review of therapeutic efficacy observed in the pharmacological treatment of ADHD based on data from controlled clinical trials...
  22. ncbi request reprint Regressive and intensive methods of electroconvulsive therapy: a brief historical note
    Gabor Gazdag
    Consultation Liaison Psychiatric Service, Szt Laszlo Hospital, Budapest, Hungary
    J ECT 23:229-32. 2007
    ..An attempt is also made to evaluate the risks and benefits of these methods from a historical perspective...
  23. ncbi request reprint How to find the way out from four rooms? The learning of "chaining" associations may shed light on the neuropsychology of the deficit syndrome of schizophrenia
    Patrícia Polgár
    Semmelweis University, Department of Psychiatry and Psychotherapy, Budapest, H1083, Balassa u 6, Hungary
    Schizophr Res 99:200-7. 2008
    ..These results indicate that the deficit syndrome is associated with prominently impaired stimulus-response reinforcement learning, which may indicate abnormal functioning of basal ganglia circuits...
  24. ncbi request reprint [Evaluation of the psychometric properties of the Calgary Depression Scale for Schizophrenics (CDSS) in a Hungarian clinical population of patients with schizophrenia]
    Judit Nagy
    ESZSZK Merényi Kórháza, Pszichiátriai Osztály, Budapest, Hungary
    Neuropsychopharmacol Hung 13:33-40. 2011
    ..Evaluation of the reliability and validity of the Hungarian version of the Calgary Depression Scale for Schizophrenics (CDSS) in a Hungarian clinical population of patients with schizophrenia...
  25. doi request reprint Association study of NRG1, DTNBP1, RGS4, G72/G30, and PIP5K2A with schizophrenia and symptom severity in a Hungarian sample
    János M Réthelyi
    Department of Psychiatry and Psychotherapy, Semmelweis University, 1083 Balassa u 6, Budapest, Hungary
    Am J Med Genet B Neuropsychiatr Genet 153:792-801. 2010
    ..Such studies have the potential to unravel the possible connection between genetic and clinical heterogeneity in schizophrenia...
  26. ncbi request reprint Antipsychotic prescription patterns in outpatient settings: 24-month results from the Intercontinental Schizophrenia Outpatient Health Outcomes (IC-SOHO) study
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Eur Neuropsychopharmacol 18:170-80. 2008
    ..001). However, treatment modification due to patient request was significantly greater for olanzapine-treated patients, compared to risperidone-, quetiapine- or haloperidol-treated patients (p<or=.001)...
  27. doi request reprint Pharmacotherapy of adult attention deficit hyperactivity disorder (ADHD): a meta-analysis
    Agnes Mészáros
    Semmelweis University, Department of Psychiatry and Psychotherapy, Budapest, Hungary
    Int J Neuropsychopharmacol 12:1137-47. 2009
    ..Nonetheless, results of this meta-analysis across all ADHD medications in adult subjects demonstrated statistically significant and clinically robust improvement in symptom severity compared to placebo treatment...
  28. pmc Károly Schaffer and his school: the birth of biological psychiatry in Hungary, 1890-1940
    Brigitta Baran
    Semmelweis University, Faculty of Medicine, Department of Psychiatry and Psychotherapy, Balassa u 6, 1083 Budapest, Hungary
    Eur Psychiatry 23:449-56. 2008
    ..The present biographical account of Károly Schaffer and his school seeks to bring this important story in the early history of biological psychiatry to a wider audience and explain why it has since been forgotten...
  29. doi request reprint Pharmacological treatment of adult ADHD
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Curr Opin Psychiatry 25:529-34. 2012
    ..This article reviews recent advances in the pharmacological treatment of adult attention deficit hyperactivity disorder (ADHD), focusing on the literature of the last 18 months...
  30. ncbi request reprint [The birth of biological therapy in Hungary: the story of László Meduna's first patient receiving convulsive therapy]
    Brigitta Baran
    Semmelweis Egyetem AOK Pszichiátriai és Pszichoterápiás Klinika
    Psychiatr Hung 23:366-75. 2008
    ..Zoltán never became symptom free again, could never be discharged and died in the institute in 1945. The authors attempt to explain possible reasons for the discrepancies found between Meduna's account and L. Zoltán's case notes...
  31. ncbi request reprint [The relationship between cognition and functional outcome in schizophrenia]
    Sarolta Komlósi
    Semmelweis Egyetem Pszichiatriai es Pszichoterapias Klinika, Budapest
    Psychiatr Hung 23:166-76. 2008
    ..Improvements in cognitive deficits are expected to lead to benefits in the everyday functioning of the patients...
  32. ncbi request reprint Prevalence and comorbidity of affective disorders in persons making suicide attempts in Hungary: importance of the first depressive episodes and of bipolar II diagnoses
    Judit Balazs
    Department of Psychiatry and Psychotherapy, Semmelweis University, Balassa str 6, 1083 Budapest, Hungary
    J Affect Disord 76:113-9. 2003
    ..The purpose of this study was to investigate the prevalence and comorbidity of affective disorders, especially current major depressive episode and bipolar disorder among suicide attempters in Hungary...
  33. doi request reprint Real-world effectiveness of antipsychotic monotherapy vs. polypharmacy in schizophrenia: To switch or to combine? A nationwide study in Hungary
    Lajos Katona
    National Health Insurance Fund Administration, Budapest, Hungary
    Schizophr Res 152:246-54. 2014
    ..We conducted a nationwide population-based study to investigate the comparative effectiveness of monotherapy versus polypharmacy in schizophrenia and other psychotic disorders...
  34. doi request reprint Genes and environments in schizophrenia: The different pieces of a manifold puzzle
    János M Réthelyi
    Department of Psychiatry and Psychotherapy, Semmelweis University, Hungary Electronic address
    Neurosci Biobehav Rev 37:2424-37. 2013
    ..New approaches, including animal studies and in vitro disease modeling, as well as innovative real-world environment assessment methods, will help to understand the complex etiology of schizophrenia. ..
  35. doi request reprint Fearful face recognition in schizophrenia: an electrophysiological study
    Sarolta Komlósi
    Semmelweis University, Department of Psychiatry and Psychotherapy, Budapest, Hungary
    Schizophr Res 149:135-40. 2013
    ....
  36. ncbi request reprint [Detailed review of epidemiologic studies on adult Attention Deficit/Hyperactivity Disorder (ADHD)]
    Viktoria Simon
    Semmelweis Egyetem, Pszichiatriai es Pszichoterapias Klinika, Budapest, Hungary
    Psychiatr Hung 22:4-19. 2007
    ..Despite the fact that it also occurs in adults, ADHD represents a barely known and rarely recognized disorder in practice. The objective of this article is to provide a detailed review of epidemiological research into ADHD in adults...
  37. ncbi request reprint [Chapters from the history of biological psychiatry: efforts made to increase the efficacy of electroconvulsive therapy]
    Gabor Gazdag
    Szt Laszló Kórház, Addiktologiai es Pszichiatriai Ambulancia, Budapest, Hungary
    Psychiatr Hung 21:351-9. 2006
    ..Side effects and complications of these methods are also dealt with in detail. Finally, an attempt is made to critically evaluate these methods in the context of contemporary ethical standards...
  38. ncbi request reprint Validity of reliability: comparison of interrater reliabilities of psychopathological symptoms
    Bertalan Petho
    Society of Research of Endogenous Psychoses 2000, Budapest, Hungary
    J Nerv Ment Dis 195:606-13. 2007
    ..It is recommended for evaluation of results of rating scales in the context of psychiatric nosology...
  39. ncbi request reprint Deinstitutionalization in Europe: two recent examples from Germany and Hungary
    Gusztáv Stubnya
    Semmelweis University, Ullöi street 26 HUN 1085 Budapest, Hungary
    Psychiatr Danub 22:406-12. 2010
    ....
  40. doi request reprint Comparative effectiveness of depot and oral second generation antipsychotic drugs in schizophrenia: a nationwide study in Hungary
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Eur Neuropsychopharmacol 23:1383-90. 2013
    ..In terms of medication differences, our data support the superior effectiveness of the depot formulation regarding all-cause discontinuation, followed by olanzapine at the efficacy rank order. ..
  41. doi request reprint Functional impairment in adults positively screened for attention-deficit hyperactivity disorder: the role of symptom presentation and executive functioning
    Bálint Szuromi
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary Electronic address
    Compr Psychiatry 54:974-81. 2013
    ..Our objective was to investigate the specific roles of two potentially important predictors of this Fi: the clinical symptom presentation and the deficit in executive functions (EFs)...
  42. doi request reprint State of psychiatry in Hungary
    Istvan Bitter
    Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary
    Int Rev Psychiatry 24:307-13. 2012
    ..The profession, patients and their caregivers should use this opportunity to modernize psychiatry in Hungary...
  43. doi request reprint [SCHIZOBANK - The Hungarian national schizophrenia biobank and its role in schizophrenia research and in personalized medicine]
    Gabriella Inczédy-Farkas
    Semmelweis Egyetem, Általános Orvostudományi Kar, Molekuláris Neurológiai Klinikai és Kutatási Központ, Neurológiai Klinika, Budapest
    Orv Hetil 151:1403-8. 2010
    ..The collection of the SCHIZOBANK is available not only to consortial partners but to other national and international research groups as well...
  44. ncbi request reprint Atropine coma: a historical note
    Gabor Gazdag
    Consultation Liaison Psychiatric Service, Szt Laszlo Hospital, Budapest, Hungary
    J ECT 21:203-6. 2005
    ..Hypotheses concerning its mode of action are briefly mentioned. The reasons why ACT never gained wider acceptance are explored in the context of both contemporary psychiatric practice and the broader sociocultural climate of the era...