A E Czeizel

Summary

Affiliation: Plant Protection Institute
Country: Hungary

Publications

  1. ncbi request reprint Use of antibiotics during pregnancy
    A E Czeizel
    WHO Collaborating Centre for the Community Control of Hereditary Diseases, Department of Human Genetics and Teratology National Institute of Public Health, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 81:1-8. 1998
  2. ncbi request reprint Orofacial clefts in Hungary. Epidemiological and genetic data, primary prevention
    A E Czeizel
    Department of Human Genetics and Teratology, National Institute of Public Health, Budapest, Hungary
    Folia Phoniatr Logop 49:111-6. 1997
  3. pmc Human germinal mutagenic effects in relation to intentional and accidental exposure to toxic agents
    A E Czeizel
    Department of Human Genetics and Teratology, National Institute of Hygiene WHO Collaborating Centre from the Community Control of Hereditary Diseases, Budapest, Hungary
    Environ Health Perspect 104:615-7. 1996
  4. ncbi request reprint Teratologic evaluation of 178 infants born to mothers who attempted suicide by drugs during pregnancy
    A E Czeizel
    Department of Human Genetics and Teratology, National Institute of Public Health WHO Collaborating Centre for the Community Control of Hereditary Diseases, Budapest, Hungary
    Obstet Gynecol 90:195-201. 1997
  5. ncbi request reprint A population-based case-control teratologic study of nalidixic acid
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases Department of Human Genetics and Teratology, National Center for Epidemiology, Budapest, Hungary
    Int J Gynaecol Obstet 73:221-8. 2001
  6. ncbi request reprint Maternal kidney stones during pregnancy and adverse birth outcomes, particularly congenital abnormalities in the offspring
    F Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Arch Gynecol Obstet 275:481-7. 2007
  7. doi request reprint A study of the teratogenic and fetotoxic effects of large doses of barbital, hexobarbital and butobarbital used for suicide attempts by pregnant women
    G Timmermann
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:109-19. 2008
  8. ncbi request reprint A population-based case-control teratologic study of ampicillin treatment during pregnancy
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Department of Human Genetics and Teratology, National Center for Epidemiology, 1026 Budapest, Hungary
    Am J Obstet Gynecol 185:140-7. 2001
  9. doi request reprint A study of the effects of large doses of medazepam used for self-poisoning in 10 pregnant women on fetal development
    J Gidai
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:61-8. 2008
  10. doi request reprint A study of the effects of large doses of glutethimide that were used for self-poisoning during pregnancy on human fetuses
    D Petik
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:69-78. 2008

Collaborators

Detail Information

Publications52

  1. ncbi request reprint Use of antibiotics during pregnancy
    A E Czeizel
    WHO Collaborating Centre for the Community Control of Hereditary Diseases, Department of Human Genetics and Teratology National Institute of Public Health, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 81:1-8. 1998
    ....
  2. ncbi request reprint Orofacial clefts in Hungary. Epidemiological and genetic data, primary prevention
    A E Czeizel
    Department of Human Genetics and Teratology, National Institute of Public Health, Budapest, Hungary
    Folia Phoniatr Logop 49:111-6. 1997
    ..Finally the recent controversial data concerning the primary prevention of isolated orofacial clefts by periconceptional folic acid-containing multivitamins are summarized...
  3. pmc Human germinal mutagenic effects in relation to intentional and accidental exposure to toxic agents
    A E Czeizel
    Department of Human Genetics and Teratology, National Institute of Hygiene WHO Collaborating Centre from the Community Control of Hereditary Diseases, Budapest, Hungary
    Environ Health Perspect 104:615-7. 1996
    ..Environmental investigations have pointed to the excessive use of trichlorfon at local fish farms as the cause...
  4. ncbi request reprint Teratologic evaluation of 178 infants born to mothers who attempted suicide by drugs during pregnancy
    A E Czeizel
    Department of Human Genetics and Teratology, National Institute of Public Health WHO Collaborating Centre for the Community Control of Hereditary Diseases, Budapest, Hungary
    Obstet Gynecol 90:195-201. 1997
    ..To identify the teratogenic risk of large doses of various drugs taken by women in attempting suicide...
  5. ncbi request reprint A population-based case-control teratologic study of nalidixic acid
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases Department of Human Genetics and Teratology, National Center for Epidemiology, Budapest, Hungary
    Int J Gynaecol Obstet 73:221-8. 2001
    ....
  6. ncbi request reprint Maternal kidney stones during pregnancy and adverse birth outcomes, particularly congenital abnormalities in the offspring
    F Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Arch Gynecol Obstet 275:481-7. 2007
    ..The possible adverse birth outcomes, particularly congenital abnormalities (CAs) in pregnant women with kidney stones (KS) previously have not been evaluated; therefore, we decided to study this possible association...
  7. doi request reprint A study of the teratogenic and fetotoxic effects of large doses of barbital, hexobarbital and butobarbital used for suicide attempts by pregnant women
    G Timmermann
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:109-19. 2008
    ..The very large doses of barbital, hexobarbital and/or butobarbital used for self-poisoning during pregnancy were not teratogenic to the children, although it must be recognized that the number of exposed children was limited...
  8. ncbi request reprint A population-based case-control teratologic study of ampicillin treatment during pregnancy
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Department of Human Genetics and Teratology, National Center for Epidemiology, 1026 Budapest, Hungary
    Am J Obstet Gynecol 185:140-7. 2001
    ....
  9. doi request reprint A study of the effects of large doses of medazepam used for self-poisoning in 10 pregnant women on fetal development
    J Gidai
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:61-8. 2008
    ..Our experiences show the feasibility and benefits of use of the self-poisoning model in estimating human teratogenic and fetotoxic risks of drugs...
  10. doi request reprint A study of the effects of large doses of glutethimide that were used for self-poisoning during pregnancy on human fetuses
    D Petik
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:69-78. 2008
    ..Very large doses of glutethimide used for a suicide attempt by 16 pregnant women did not produce teratogenic or fetotoxic (including neurotoxic) effects in their children...
  11. doi request reprint A study of teratogenic and fetotoxic effects of large doses of meprobamate used for a suicide attempt by 42 pregnant women
    G Timmermann
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:97-107. 2008
    ..Very large doses of meprobamate that were used for self-poisoning during pregnancy did not result in teratogenic or fetotoxic, including neurotoxic, effects on fetal development...
  12. ncbi request reprint A population-based case-control teratologic study of oral chloramphenicol treatment during pregnancy
    A E Czeizel
    WHO Collaborating Centre for the Community Control of Hereditary Diseases Department of Human Genetics and Teratology, National Center for Epidemiology, Budapest, Hungary
    Eur J Epidemiol 16:323-7. 2000
    ..Thus, chloramphenicol treatment during early pregnancy presents little, if any, teratogenic risk to the fetus in humans...
  13. doi request reprint A study of the potential teratogenic effects of large doses of drugs rarely used for a suicide attempt during pregnancy
    G Timmermann
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:121-31. 2008
    ..Experience of the authors shows the feasibility and benefits of using the self-poisoning model in estimating human teratogenic/fetotoxic risks of exposure to drugs...
  14. doi request reprint A study of the teratogenic and fetotoxic effects of large doses of chlordiazepoxide used for self-poisoning by 35 pregnant women
    J Gidai
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:41-51. 2008
    ..Very large doses of chlordiazepoxide used for suicide attempts during pregnancy did not induce a higher rate of congenital abnormalities but were associated with dose-dependent intrauterine growth retardation...
  15. doi request reprint Self-poisoning during pregnancy as a model for teratogenic risk estimation of drugs
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:11-28. 2008
    ..g., dose-response estimation) in comparison with other methods. It is suggested that an international monitoring system of self-poisoned pregnant women should be established to provide a larger database...
  16. doi request reprint A study of the teratogenic and fetotoxic effects of large doses of amobarbital used for a suicide attempt by 14 pregnant women
    D Petik
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:79-85. 2008
    ..Exposure to very large doses of amobarbital that were used for self-poisoning during pregnancy did not produce teratogenic effects in this study...
  17. ncbi request reprint Recall bias in a case-control surveillance system on the use of medicine during pregnancy
    M Rockenbauer
    Department of Human Genetics and Teratology, Center for Epidemiology, Foundation for Community Control and Hereditary Diseases, Budapest, Hungary
    Epidemiology 12:461-6. 2001
    ..A case-control surveillance system of this type may frequently cause spurious associations, with biased odds ratios up to a factor of 1.9...
  18. doi request reprint No association found between use of very large doses of diazepam by 112 pregnant women for a suicide attempt and congenital abnormalities in their offspring
    J Gidai
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:29-39. 2008
    ..The very large doses of diazepam used for self-poisoning during pregnancy did not increase the rate of congenital abnormalities in the offspring...
  19. ncbi request reprint Use of cephalosporins during pregnancy and in the presence of congenital abnormalities: a population-based, case-control study
    A E Czeizel
    Department of Human Genetics and Teratology, National Center for Epidemiology, World Health Organization Collaborating Center for the Community Control of Hereditary Diseases, Budapest, Hungary
    Am J Obstet Gynecol 184:1289-96. 2001
    ..However, further studies are needed to clarify the teratogenic and fetal toxic effects of different cephalosporins separately...
  20. ncbi request reprint Timing of suicide attempts by self-poisoning during pregnancy and pregnancy outcomes
    A E Czeizel
    Department of Human Genetics and Teratology, National Institute of Public Health WHO Collaborating Centre for the Community Control of Hereditary Diseases, Budapest, Hungary
    Int J Gynaecol Obstet 65:39-45. 1999
    ..The purpose of this study was to examine the timing and consequences of suicide attempts by self-poisoning during pregnancy...
  21. doi request reprint A study of the potential teratogenic effect of large doses of promethazine used for a suicide attempt by 32 pregnant women
    D Petik
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:87-96. 2008
    ..Our experience shows the feasibility and benefits of using the self-poisoning model in estimating human teratogenic/fetotoxic risks of exposure to drugs...
  22. doi request reprint An evaluation of data for 10 children born to mothers who attempted suicide by taking large doses of alprazolam during pregnancy
    J Gidai
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Toxicol Ind Health 24:53-60. 2008
    ..Our study shows that the self-poisoning model is feasible and provides beneficial information for use in estimating human teratogenic and fetotoxic risks of drugs...
  23. ncbi request reprint The teratogenic risk of trimethoprim-sulfonamides: a population based case-control study
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Reprod Toxicol 15:637-46. 2001
    ..These agents have antifolate effects and other antifolate agents can induce multiple congenital abnormalities, neural-tube defects, cardiovascular, and other malformations in animal experiments and in humans...
  24. ncbi request reprint Augmentin treatment during pregnancy and the prevalence of congenital abnormalities: a population-based case-control teratologic study
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Department of Human, Genetics and Teratology, National Center for Epidemiology, 1026 Budapest, Torokvesz Lejto 32, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 97:188-92. 2001
    ..To study the human teratogenic potential of augmentin (amoxicillin+clavulanic acid) treatment during pregnancy...
  25. ncbi request reprint A population-based case-control study of the safety of oral anti-tuberculosis drug treatment during pregnancy
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Department of Human Genetics and Teratology, National Center for Epidemiology, Budapest, Hungary
    Int J Tuberc Lung Dis 5:564-8. 2001
    ..To study the human teratogenic potential of isoniazid and other anti-tuberculosis drug treatment during pregnancy...
  26. ncbi request reprint Nitrofurantoin and congenital abnormalities
    A E Czeizel
    Department of Human Genetics and Teratology, Foundation for the Community Control of Hereditary Diseases, National Centre for Epidemiology, Torokvesz Lejto 32, 1026, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 95:119-26. 2001
    ..To study human teratogenic potential of oral nitrofurantoin treatment during pregnancy. MATERIALS and..
  27. doi request reprint Possible association of folic acid supplementation during pregnancy with reduction of preterm birth: a population-based study
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Eur J Obstet Gynecol Reprod Biol 148:135-40. 2010
    ..Thus the possible fetal growth promoting and/or preterm birth reducing effect of vitamin supplements in the second and mainly in the third trimester was studied...
  28. ncbi request reprint A population-based case-control teratologic study of oral erythromycin treatment during pregnancy
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Department of Human Genetics and Teratology, National Center for Epidemiology, Budapest, Hungary
    Reprod Toxicol 13:531-6. 1999
    ..Thus, treatment with oral erythromycin during pregnancy did not present detectable teratogenic risk to the fetus...
  29. ncbi request reprint A population-based case-control teratologic study of furazidine, a nitrofuran-derivative treatment during pregnancy
    A E Czeizel
    Department of Human Genetics and Teratology, National Center for Epidemiology, Budapest, Hungary
    Clin Nephrol 53:257-63. 2000
    ..To study human teratogenic potential of furazidine treatment during pregnancy...
  30. ncbi request reprint Description and mission evaluation of the Hungarian case-control surveillance of congenital abnormalities, 1980-1996
    A E Czeizel
    Foundation for Community Control of Hereditary Diseases, Budapest, Hungary
    Teratology 63:176-85. 2001
    ....
  31. ncbi request reprint Maternal employment status and isolated orofacial clefts in Hungary
    E Puho
    National Centre for Epidemiology, Department of Human Genetics and Teratology, Budapest, Hungary
    Cent Eur J Public Health 13:144-8. 2005
    ..To study the role of maternal employment status as indicator of socioeconomic status in the origin of isolated orofacial clefts (OFC) and in the use of periconceptional folic acid/multivitamin supplementation...
  32. ncbi request reprint The higher rate of multiple births after periconceptional multivitamin supplementation: an analysis of causes
    A E Czeizel
    Department of Human Genetics and Teratology, National Institute of Hygiene, Budapest, Hungary
    Acta Genet Med Gemellol (Roma) 43:175-84. 1994
    ..anovulation. Nonetheless, our study showed that periconceptional multivitamin supplementation, with or without ovarian stimulation, increases the rate of multiple births...
  33. ncbi request reprint Oral tinidazole treatment during pregnancy and teratogenesis
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Int J Gynaecol Obstet 83:305-6. 2003
  34. ncbi request reprint Vaginal treatment with povidone--iodine suppositories during pregnancy
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Int J Gynaecol Obstet 84:83-5. 2004
  35. ncbi request reprint Maternal urinary tract infection and related drug treatments during pregnancy and risk of congenital abnormalities in the offspring
    F Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    BJOG 113:1465-71. 2006
    ..Only one study showed an association with atrial septal defect, thus we decided to check this possible association...
  36. ncbi request reprint Congenital abnormalities and indicators of germinal mutations in the vicinity of an acrylonitrile producing factory
    A E Czeizel
    WHO Collaborating Centre for the Community Control of Hereditary Diseases, Department of Human Genetics and Teratology, National Centre of Epidemiology, Budapest, Hungary
    Mutat Res 427:105-23. 1999
    ..The detailed analysis of congenital abnormalities in all settlements of a given territory may help to detect clusters of congenital abnormalities and their possible relation to the environmental hazards...
  37. ncbi request reprint Gestational age and prevalence of preterm birth after vaginal metronidazole treatment during pregnancy
    Z Kazy
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Int J Gynaecol Obstet 87:161-2. 2004
  38. ncbi request reprint Smoking and alcohol drinking during pregnancy. The reliability of retrospective maternal self-reported information
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Cent Eur J Public Health 12:179-83. 2004
    ..The reliability of retrospective maternal self-reported information regarding smoking and alcohol drinking during pregnancy seemed necessary to be checked...
  39. ncbi request reprint Ovarian cysts, clomiphene therapy, and the risk of neural tube defects
    F Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Int J Gynaecol Obstet 100:86-8. 2008
  40. ncbi request reprint Drug exposure in pregnant women
    A E Czeizel
    Foundation for the Communication Control of Hereditary Diseases, Budapest, Hungary
    Lupus 13:740-5. 2004
    ..Medical doctors and other experts therefore need more education to know the principles and findings of modern human teratology because it may help us to have a better balance between the risk and benefit of drug use during pregnancy...
  41. ncbi request reprint A changing pattern in the association of oral contraceptives and the different groups of congenital limb deficiencies
    A E Czeizel
    Department of Human Genetics and Teratology, National Institute of Hygiene, Budapest, Hungary
    Contraception 51:19-24. 1995
    ..05 mg) used in the periconceptional period was found in the mothers of cases with terminal transverse defect (adjusted relative odds 1.9 with 95% confidence interval of 1.1-3.4). This risk is minimised by the use of recent low-dose pills...
  42. ncbi request reprint A case-control study of congenital abnormality and dimenhydrinate usage during pregnancy
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Arch Gynecol Obstet 271:113-8. 2005
    ..The objective was to determine the teratogenicity of dimenhydrinate, an anti-emetic drug...
  43. ncbi request reprint Tetanus toxoid and congenital abnormalities
    A E Czeizel
    Department of Human Genetics and Teratology, National Institute of Public Health WHO Collaborating Centre for the Community Control of Hereditary Diseases, Budapest, Hungary
    Int J Gynaecol Obstet 64:253-8. 1999
    ..To study the human teratogenic potential of tetanus vaccination during pregnancy...
  44. ncbi request reprint The possible preterm birth preventive effect of ampicillin during pregnancy
    Z Kazy
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Arch Gynecol Obstet 274:215-21. 2006
    ..To study the possible association between oral ampicillin treatment during pregnancy and pregnancy complications, in addition to birth outcomes, particularly preterm birth...
  45. ncbi request reprint Teratogenic effects of vaginal boric acid treatment during pregnancy
    N Acs
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, and Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Int J Gynaecol Obstet 93:55-6. 2006
  46. ncbi request reprint Case-control study of teratogenic potential of thiethylperazine, an anti-emetic drug
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    BJOG 110:497-9. 2003
    ..Thus, the aim of the study was to investigate the possible human teratogenic effect of thiethylperazine...
  47. ncbi request reprint Phenolphthalein treatment in pregnant women and congenital abnormalities in their offspring: A population-based case-control study
    F Banhidy
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Drug Discov Ther 2:357-67. 2008
    ..In conclusion phenolphthalein treatment in pregnant women associates with a higher risk for Hirschsprung's disease in their children, but this finding is only a signal which needs confirmation or rejection in other studies...
  48. ncbi request reprint Primary prevention of neural-tube defects and some other major congenital abnormalities: recommendations for the appropriate use of folic acid during pregnancy
    A E Czeizel
    Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary
    Paediatr Drugs 2:437-49. 2000
    ..This provides a practical means to ensure all women, especially those from lower socioeconomic backgrounds and/or with a low level of education who are more likely to have unplanned pregnancies, have an adequate folic acid intake...
  49. ncbi request reprint The check-up of reproductive health and genetic counseling
    A E Czeizel
    Department of Human Genetics and Teratology, WHO Collaborating Centre for the Community Control of Hereditary Diseases, National Institute of Hygiene, Budapest, Hungary
    Genet Couns 3:61-6. 1992
    ....
  50. ncbi request reprint Association of epilepsy with different groups of microcephaly
    G M Abdel-Salam
    Department of Human Genetics and Teratology, National Center for Epidemiology, Budapest, Hungary
    Dev Med Child Neurol 42:760-7. 2000
    ..The pathogenetic classification proposed is of value in delineating the prevalence of epilepsy and LD in the different varieties of MC as compared with the etiological classification...
  51. ncbi request reprint Validation studies of drug exposures in pregnant women
    A E Czeizel
    Foundation for Community Control of Hereditary Diseases, and Department of Obstetrics, Gynecology and Gynecological Oncology, St Stephen Hospital, Budapest, Hungary
    Pharmacoepidemiol Drug Saf 12:409-16. 2003
    ..Thus the evaluation of drug use on the basis of medically recorded prescribed drugs and/or usual recommendations produces a bias thus it is necessary to complete it with information from the patients...
  52. ncbi request reprint Frequency of the R3500Q mutation of the apolipoprotein B-100 gene in a sample screened clinically for familial hypercholesterolemia in Hungary
    A Kalina
    Cardiology Department, MAV Hospital, Táncsics M 20, 1014, Budapest, Hungary
    Atherosclerosis 154:247-51. 2001
    ..Because FDB is one of the independent causes of early onset CHD, the R3500Q mutation should be considered in families with a high frequency of cardiovascular diseases...