Laszlo Pajor

Summary

Country: Hungary

Publications

  1. ncbi request reprint Combined metaphase, interphase cytogenetic, and flow cytometric analysis of DNA content of pediatric acute lymphoblastic leukemia
    L Pajor
    Department of Pathology, University Medical School of Pecs, Hungary
    Cytometry 34:87-94. 1998
  2. ncbi request reprint Increased incidence of monoclonal B-cell infiltrate in chronic myeloproliferative disorders
    Laszlo Pajor
    Department of Pathology, Medical Faculty, University of Pecs, Pecs, Hungary
    Mod Pathol 17:1521-30. 2004
  3. ncbi request reprint Phenotypic and genotypic analyses of blastic cell population suggest that pure B-lymphoblastic leukemia may arise from myelodysplastic syndrome
    L Pajor
    Department of Pathology, University Medical School of Pecs, Hungary
    Leuk Res 22:13-7. 1998
  4. ncbi request reprint Philadelphia chromosome and/or bcr-abl mRNA-positive primary thrombocytosis: morphometric evidence for the transition from essential thrombocythaemia to chronic myeloid leukaemia type of myeloproliferation
    L Pajor
    Department of Pathology, Faculty of Medicine, University of Pecs, Pecs, and 3rd Department of Internal Medicine, Semmelweis Hospital, Miskolc, Hungary
    Histopathology 42:53-60. 2003
  5. ncbi request reprint Coexistence of chronic myeloid leukemia and hairy cell leukemia of common clonal origin
    Laszlo Pajor
    Department of Pathology, Medical Faculty, University of Pecs, Pecs, Hungary
    Cancer Genet Cytogenet 134:114-7. 2002
  6. doi request reprint A 7.5-year prospective study of longer than 18 months type-specific human papillomavirus persistence in a routine cytology-based cervical screening population of about 31,000 women in West Germany
    Krisztina Kovacs
    Department of Pathology, Faculty of Medicine, University of Pecs, Hungary
    Eur J Cancer Prev 18:307-15. 2009
  7. doi request reprint Multiplex ligation-dependent probe amplification and fluorescence in situ hybridization are complementary techniques to detect cytogenetic abnormalities in multiple myeloma
    Donat Alpar
    Department of Pathology, Medical School, University of Pecs, Pecs, Hungary
    Genes Chromosomes Cancer 52:785-93. 2013
  8. doi request reprint Automated FISH analysis using dual-fusion and break-apart probes on paraffin-embedded tissue sections
    Donat Alpar
    Department of Pathology, Faculty of Medicine, University of Pecs, Pecs, Hungary
    Cytometry A 73:651-7. 2008
  9. ncbi request reprint Correlation between BCR-ABL expression and tumor burden is restricted to the transition from minor to major cytogenetic response in interferon treated CML patients
    Laszlo Kereskai
    University of Pecs, Faculty of Medicine, Department of Pathology, Pecs, Hungary
    Pathol Oncol Res 9:174-9. 2003
  10. doi request reprint Urovysion: Considerations on modifying current evaluation scheme, including immunophenotypic targeting and locally set, statistically derived diagnostic criteria
    Gabor Pajor
    Department of Pathology, Faculty of Medicine, University of Pecs, Hungary
    Cytometry A 79:375-82. 2011

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Combined metaphase, interphase cytogenetic, and flow cytometric analysis of DNA content of pediatric acute lymphoblastic leukemia
    L Pajor
    Department of Pathology, University Medical School of Pecs, Hungary
    Cytometry 34:87-94. 1998
    ..Flow cytometric data showed aneuploidy in three of the six aneuploid leukemia patients. The results suggest that interphase cytogenetics might be more accurate compared with flow cytometry and metaphase analysis to reveal aneuploidy...
  2. ncbi request reprint Increased incidence of monoclonal B-cell infiltrate in chronic myeloproliferative disorders
    Laszlo Pajor
    Department of Pathology, Medical Faculty, University of Pecs, Pecs, Hungary
    Mod Pathol 17:1521-30. 2004
    ..Modern Pathology (2004) 17, 1521-1530, advance online publication, 16 July 2004; doi:10.1038/modpathol.3800225...
  3. ncbi request reprint Phenotypic and genotypic analyses of blastic cell population suggest that pure B-lymphoblastic leukemia may arise from myelodysplastic syndrome
    L Pajor
    Department of Pathology, University Medical School of Pecs, Hungary
    Leuk Res 22:13-7. 1998
    ..These phenotypic and genotypic analyses of the blastic cell population suggest that myelodysplastic syndrome may transform to pure acute lymphoblastic leukemia of B-cell origin...
  4. ncbi request reprint Philadelphia chromosome and/or bcr-abl mRNA-positive primary thrombocytosis: morphometric evidence for the transition from essential thrombocythaemia to chronic myeloid leukaemia type of myeloproliferation
    L Pajor
    Department of Pathology, Faculty of Medicine, University of Pecs, Pecs, and 3rd Department of Internal Medicine, Semmelweis Hospital, Miskolc, Hungary
    Histopathology 42:53-60. 2003
    ..The incidence, bone marrow morphology and genetic features of bcr+ essential thrombocythaemia were investigated...
  5. ncbi request reprint Coexistence of chronic myeloid leukemia and hairy cell leukemia of common clonal origin
    Laszlo Pajor
    Department of Pathology, Medical Faculty, University of Pecs, Pecs, Hungary
    Cancer Genet Cytogenet 134:114-7. 2002
    ....
  6. doi request reprint A 7.5-year prospective study of longer than 18 months type-specific human papillomavirus persistence in a routine cytology-based cervical screening population of about 31,000 women in West Germany
    Krisztina Kovacs
    Department of Pathology, Faculty of Medicine, University of Pecs, Hungary
    Eur J Cancer Prev 18:307-15. 2009
    ..This may influence future screening strategies and therapy decisions...
  7. doi request reprint Multiplex ligation-dependent probe amplification and fluorescence in situ hybridization are complementary techniques to detect cytogenetic abnormalities in multiple myeloma
    Donat Alpar
    Department of Pathology, Medical School, University of Pecs, Pecs, Hungary
    Genes Chromosomes Cancer 52:785-93. 2013
    ..Since balanced aberrations are key to prognostic classification of this disease, MLPA and i-FISH should be applied as complementary techniques in diagnostic pathology...
  8. doi request reprint Automated FISH analysis using dual-fusion and break-apart probes on paraffin-embedded tissue sections
    Donat Alpar
    Department of Pathology, Faculty of Medicine, University of Pecs, Pecs, Hungary
    Cytometry A 73:651-7. 2008
    ..Using the DF probes resulted in lower false positivity, which was less affected by signal numbers per grid units...
  9. ncbi request reprint Correlation between BCR-ABL expression and tumor burden is restricted to the transition from minor to major cytogenetic response in interferon treated CML patients
    Laszlo Kereskai
    University of Pecs, Faculty of Medicine, Department of Pathology, Pecs, Hungary
    Pathol Oncol Res 9:174-9. 2003
    ..This indicates that the BCR-ABL expression and the tumor burden are largely independent variables...
  10. doi request reprint Urovysion: Considerations on modifying current evaluation scheme, including immunophenotypic targeting and locally set, statistically derived diagnostic criteria
    Gabor Pajor
    Department of Pathology, Faculty of Medicine, University of Pecs, Hungary
    Cytometry A 79:375-82. 2011
    ..Furthermore, by providing additional quantitative information about tumor characteristics, is likely to have therapy relevant value in the future...
  11. ncbi request reprint Lineage-specific clonality analysis of chronic myeloproliferative disorders and myelodysplastic syndrome by human androgen receptor assay
    Pál Jáksó
    Department of Pathology, Faculty of Medicine, University of Pecs, Pecs, H 7643, Hungary
    Pathol Oncol Res 13:114-22. 2007
    ..The results of HUMARA, available in 73% of the female patients, supported the clinicopathological data in 84% as well as proved pluripotent stem cell origin in 31-75% and 21% of CMPDs and MDS, respectively...
  12. doi request reprint Detection of early precursors of t(12;21) positive pediatric acute lymphoblastic leukemia during follow-up
    Renáta László
    Department of Pathology, University of Pécs Medical Center, Pecs, Hungary
    Pediatr Blood Cancer 54:158-60. 2010
    ..CD10+ ancestor cells with germline antigen receptors, but silent TEL/AML1 expression, may reside in the lymphoid stem cell compartment of treated t(12;21)-positive patients and might act as a potential source of cells for late relapses...
  13. doi request reprint Sex chromosome changes after sex-mismatched allogeneic bone marrow transplantation can mislead the chimerism analysis
    Donat Alpar
    Department of Pathology, Faculty of Medicine, University of Pecs, Pecs, Hungary
    Pediatr Blood Cancer 55:1239-42. 2010
    ..Sex chromosome changes after allo-BMT can cause significant difficulties in chimerism analysis...
  14. ncbi request reprint Multiple constitutional chromosome translocations of familial nature in Philadelphia chromosome-positive chronic myeloid leukemia: a report on a unique case
    Bela Kajtar
    Department of Pathology, 1st Department of Internal Medicine, University of Pecs, Hungary
    Int J Hematol 82:347-50. 2005
    ..At present, no direct evidence exists to support a causative relationship between the familial translocations and leukemogenesis...
  15. doi request reprint Automated signal pattern evaluation of a bladder cancer specific multiprobe-fish assay applying a user-trainable workstation
    Gabor Pajor
    Department of Pathology, Faculty of Medicine, University of Pecs, Pecs, Hungary
    Microsc Res Tech 75:814-20. 2012
    ..Our aim was to eliminate human interaction by automating the process, using an adoptable, automated image acquisition, and analysis system...
  16. doi request reprint Evolutionary sequence of cytogenetic aberrations during the oncogenesis of plasma cell disorders. Direct evidence at single cell level
    Zsófia Nagy
    Department of Pathology, University of Pecs, Pecs, Hungary
    Leuk Res 35:1114-6. 2011
    ..In 22% of all cases with recurrent IGH translocation, this aberration was presented only in a subset of purified plasma cells questioning its initiating role...
  17. doi request reprint State-of-the-art FISHing: automated analysis of cytogenetic aberrations in interphase nuclei
    Gabor Pajor
    Department of Pathology, University of Pecs, Medical School, Pecs, Hungary
    Cytometry A 81:649-63. 2012
    ....
  18. doi request reprint Crystal-storing histiocytosis associated with only one of two consecutive, but genetically unrelated B-cell lymphomas
    Renáta László
    Department of Pathology, Faculty of Medicine, University of Pecs, 12 Szigeti Street, H 7624, Pecs, Hungary
    Pathol Res Pract 205:273-8. 2009
    ..This might indicate that the unique condition responsible for the crystal formation is likely to rely on the sequence of the first clonally rearranged heavy chain exhibiting much higher CDRIII pI value (6.0) than the average...
  19. ncbi request reprint Automated detection of residual leukemic cells by consecutive immunolabeling for CD10 and fluorescence in situ hybridization for ETV6/RUNX1 rearrangement in childhood acute lymphoblastic leukemia
    Donat Alpar
    Department of Pathology, Faculty of Medicine, University of Pecs, 12 Szigeti Str, H 7624, Pecs, Hungary
    Cancer Genet Cytogenet 173:23-30. 2007
    ..09%) allows detection of leukemic cells with high accuracy, even a bit below the tumor load dilution of 10(-3), a value reported to be critical in clinical decision making...
  20. doi request reprint Increased efficiency of detecting genetically aberrant cells by UroVysion test on voided urine specimens using automated immunophenotypical preselection of uroepithelial cells
    Gabor Pajor
    Department of Pathology, Faculty of Medicine, University of Pecs, Hungary
    Cytometry A 73:259-65. 2008
    ..FISH analysis of phenotypically preselected urothelial cells might represent a reliable asset in surveillance of low stage-low grade TCCs...
  21. ncbi request reprint Histopathologic abnormalities of the lymphoreticular tissues in organic cation transporter 2 deficiency: evidence for impaired B cell maturation
    Katalin Komlosi
    Department of Medical Genetics and Child Development, University of Pecs, Pecs, Hungary
    J Pediatr 150:109-111.e2. 2007
    ..This is indicative of impaired antigen driven B cell affinity maturation. Defective humoral immune response might explain the recurrent infections in untreated organic cation transporter 2 deficiency...
  22. doi request reprint Pheno- and genotypic features of Epstein-Barr virus associated B-cell lymphoproliferations in peripheral T-cell lymphomas
    Gábor Smuk
    Department of Pathology, University of Pécs Medical Center, 12 Szigeti St, Pecs, Hungary
    Pathol Oncol Res 16:377-83. 2010
    ....
  23. doi request reprint [Multidrug resistance in chronic lymphocytic leukemia]
    Tamás Szendrei
    Pecsi Tudomanyegyetem, Orvostudományi és Egészségtudományi Centrum I Belgyógyászati Klinika, Hematológiai Osztály, Pecs, Hungary
    Orv Hetil 149:161-7. 2008
    ....
  24. doi request reprint MLPA is a powerful tool for detecting lymphoblastic transformation in chronic myeloid leukemia and revealing the clonal origin of relapse in pediatric acute lymphoblastic leukemia
    Donat Alpar
    Department of Pathology, University of Pecs, Pecs, Hungary
    Cancer Genet 205:465-9. 2012
    ..In summary, we have demonstrated the versatility of MLPA by using this cost-effective technique for two new applications...
  25. ncbi request reprint Automated fluorescent in situ hybridization (FISH) analysis of t(9;22)(q34;q11) in interphase nuclei
    Bela Kajtar
    Department of Pathology, Faculty of Medicine, University of Pecs, Hungary
    Cytometry A 69:506-14. 2006
    ..In this article, the capabilities of a commercially available automated image acquisition and analysis system were determined by detecting t(9;22)(q34;q11) in interphase nuclei of peripheral leukocytes...
  26. ncbi request reprint [Chronic lymphocytic leukaemia: an autoimmune disorder? Prognostic factors and the current view of pathogenesis]
    Laszlo Pajor
    Pecsi Tudomanyegyetem, Általános Orvostudományi Kar, Patológiai Intézet, Pecs
    Orv Hetil 148:867-78. 2007
    ....
  27. doi request reprint [From the surgical field to the microscope. A new tool to identify the lymph node specimens in oncologic surgery]
    F Tamás Molnár
    Pécsi Tudományegyetem Klinikai Központ Sebészeti Klinika 7634 Pécs Ifjúság u 13
    Magy Seb 64:6-11. 2011
    ..An integrated sterile and disposable lymphnode tray system is presented here for applications in the different fields of cancer surgery of the upper GI tract, retroperitoneum (gynecology, urology) and ear-nose-throat surgery...
  28. ncbi request reprint [Molecular genetic methods in anaplastic large cell lymphoma]
    Arpad Szomor
    Pecsi Tudomanyegyetem, Általános Orvostudományi Kar, I Belgyógyászati Klinika, Pecs
    Orv Hetil 144:1815-7. 2003
    ..Anaplastic large cell lymphoma belongs to a relatively good prognostic group of high grade non-Hodgkin lymphomas. Molecular genetic methods can provide great help in the differential diagnosis of the disease...
  29. ncbi request reprint [Complex analysis of prognostic factors in chronic lymphocytic leukemia]
    Bela Kajtar
    Pecsi Tudomanyegyetem, Általános Orvostudományi Kar, Patológiai Intézet, Pecs
    Orv Hetil 148:737-43. 2007
    ..Many new prognostic factors established in recent years in chronic lymphocytic leukemia. May help predicting survival...
  30. ncbi request reprint [Cytogenetic and molecular monitoring of chronic myeloid leukemia]
    Bela Kajtar
    Pecsi Tudomanyegyetem, Általános Orvostudományi Kar, Patológiai Intézet, Pecs
    Orv Hetil 147:963-70. 2006
    ..The present study shows the most important characteristics of these methods based on the literature and data acquired from 1165 samples of 197 patients detected by the authors...
  31. ncbi request reprint Cytogenetic abnormalities of alveolar soft-part sarcomas using interphase fluorescent in situ hybridization: trisomy for chromosome 7 and monosomy for chromosomes 8 and 18 seem to be characteristic of the tumor
    T Tornoczky
    Department of Pathology, Faculty of General Medicine, Pécs University of Sciences, Hungary
    Virchows Arch 438:173-80. 2001
    ..Most frequent and repeated numerical changes, which seem to be characteristic of the neoplasm and may play an important part in its pathogenesis and/or progression, were trisomy 7, monosomy 8 and monosomy 18...
  32. ncbi request reprint High mitotic index associated with poor prognosis in gastrointestinal autonomic nerve tumour
    T Tornoczky
    Department of Pathology, University Medical School Pecs, Hungary
    Histopathology 35:121-8. 1999
    ....
  33. ncbi request reprint Cytogenetic profile of primary pituitary germinoma
    E Gomori
    Department of Pathology, Medical School, University of Pecs, Hungary
    J Neurooncol 50:251-5. 2000
    ..The child was treated postoperatively by radiation and now appears well with only minor neurological deficits. At 3-year follow-up no recurrent tumor mass could be demonstrated...
  34. pmc Frequent occurrence of low grade cases among metastatic gastrointestinal stromal tumours
    T Tornoczky
    Department of Pathology, Medical School, University of Pecs, Szigeti ut 12, H 7643, Hungary
    J Clin Pathol 56:363-7. 2003
    ..This report analyses the characteristics of seven metastasising GISTs and compares clinicopathological parameters of the metastatic and non-metastatic groups...
  35. pmc Solid and papillary epithelial neoplasm arising in heterotopic pancreatic tissue of the mesocolon
    T Tornoczky
    Department of Pathology, University Medical School of Pecs, Hungary
    J Clin Pathol 54:241-5. 2001
    ..This report summarises all the published extrapancreatic SPENs and documents the sixth such case arising from heterotopic pancreatic tissue of the transverse mesocolon in a 15 year old girl...
  36. ncbi request reprint Characteristics of advanced- and non advanced sporadic polypoid colorectal adenomas: correlation to KRAS mutations
    Enkh Amar Yadamsuren
    Department of Pathology, Faculty of General Medicine, University of Pecs, Szigeti str 12, 7624, Pecs, Hungary
    Pathol Oncol Res 18:1077-84. 2012
    ..KRAS mutation is very strongly associated with a villous architecture and through villous component expansion, KRAS mutations may increase risk of tumor progression in sporadic colorectal polypoid adenomas...
  37. ncbi request reprint Nucleolin and fibrillarin expression in stimulated lymphocytes and differentiating HL-60 cells. A flow cytometric assay
    G Mehes
    Department of Pathology, University Medical School of Pecs, Hungary
    Cell Prolif 28:329-36. 1995
    ..The data support other observations that nucleolin is a stabile structural protein at the ribosomal genes while fibrillarin may have a more specific functional role in nucleologenesis and ribosome production...
  38. ncbi request reprint Rare sellar region tumors
    D J Halbauer
    Department of Pathology, Faculty of Medicine, Pecs, Hungary
    Pathol Oncol Res 9:134-7. 2003
    ..All tumors were resected and histologically analyzed. Their biological behaviour was favorable with a 10-year follow-up demonstrating no recurrent tumor mass...
  39. ncbi request reprint Genotypic analysis in primary systemic anaplastic large cell lymphoma
    Arpad Szomor
    First Department of Medicine, University of Pecs, 7624 Pecs, Hungary
    Pathol Oncol Res 9:104-6. 2003
    ..T(2;5) translocation was demonstrated in 2 cases, there was no t(1;2) translocation. In most cases the molecular genetic results were found to be in agreement with immunophenotypic data...
  40. doi request reprint Evidence of O-linked N-acetylglucosamine in diabetic nephropathy
    Peter Degrell
    2nd Department of Medicine and Nephrological Center, University of Pecs, Hungary
    Life Sci 84:389-93. 2009
    ....
  41. doi request reprint Prevalence and genotype distribution of multiple human papillomavirus infection in the uterine cervix: a 7.5-year longitudinal study in a routine cytology-based screening population in West Germany
    Krisztina Kovacs
    Department of Pathology, Faculty of Medicine, University of Pecs, Pecs, Hungary
    J Med Virol 80:1814-23. 2008
    ..Given the significance of HPV vaccination and its expected influence on immunized populations, it is essential to gain additional insights into the natural course and pathogenic effect of multiple HPV infection longitudinally...
  42. ncbi request reprint Phenotypic manifestations of the OCTN2 V295X mutation: sudden infant death and carnitine-responsive cardiomyopathy in Roma families
    Bela Melegh
    Department of Medical Genetics and Child Development, University of Pecs, Pecs, Hungary
    Am J Med Genet A 131:121-6. 2004
    ..The mutant gene derived from five non-consanguineous grandparents, each of them having 6-14 brothers and sisters. This alone suggests a wide ancestral spread of the mutation in certain Roma subpopulations...
  43. ncbi request reprint The role of androgen receptors in the dynamic process of prostate cancer: their analytical determination in biopsy material
    Oliver Pinter
    Department of Urology, Medical Faculty, University of Szeged, Szeged, Hungary
    In Vivo 18:809-12. 2004
    ..The investigation demonstrated that determination of the number of receptors itself is not of prognostic value, but it does provide information to supplement the other parameters relating to the state...