B Novak

Summary

Country: Hungary

Publications

  1. ncbi request reprint Mathematical model of the fission yeast cell cycle with checkpoint controls at the G1/S, G2/M and metaphase/anaphase transitions
    B Novak
    Department of Agricultural Chemical Technology, Technical University of Budapest, Hungary
    Biophys Chem 72:185-200. 1998
  2. pmc Model scenarios for evolution of the eukaryotic cell cycle
    B Novak
    Department of Agricultural Chemical Technology, Technical University of Budapest, Hungary
    Philos Trans R Soc Lond B Biol Sci 353:2063-76. 1998
  3. ncbi request reprint Finishing the cell cycle
    B Novak
    Department of Agricultural Chemical Technology, Technical University of Budapest, Gellert ter 4, Budapest, 1521, Hungary
    J Theor Biol 199:223-33. 1999
  4. ncbi request reprint Mitotic control in the absence of cdc25 mitotic inducer in fission yeast
    A Sveiczer
    Department of Agricultural Chemical Technology, Technical University of Budapest, Szt Gellert ter 4, Hungary
    J Cell Sci 112:1085-92. 1999
  5. pmc Modeling the fission yeast cell cycle: quantized cycle times in wee1- cdc25Delta mutant cells
    A Sveiczer
    Department of Agricultural Chemical Technology, Budapest University of Technology and Economics, 1521 Budapest, Szt Gellert ter 4, Hungary
    Proc Natl Acad Sci U S A 97:7865-70. 2000
  6. ncbi request reprint Regularities and irregularities in the cell cycle of the fission yeast, Schizosaccharomyces pombe (a review)
    A Sveiczer
    Department of Agricultural Chemical Technology, Budapest University of Technology and Economics Szt Gellért tér 4, H 1111 Budapest, Hungary
    Acta Microbiol Immunol Hung 49:289-304. 2002
  7. ncbi request reprint A stochastic, molecular model of the fission yeast cell cycle: role of the nucleocytoplasmic ratio in cycle time regulation
    A Sveiczer
    Department of Agricultural Chemical Technology, Budapest University of Technology and Economics, 1521 Budapest, Szt Gellert ter 4, Hungary
    Biophys Chem 92:1-15. 2001
  8. ncbi request reprint The size control of fission yeast revisited
    A Sveiczer
    Department of Agricultural Chemical Technology, Technical University of Budapest, Hungary
    J Cell Sci 109:2947-57. 1996
  9. ncbi request reprint Modelling the controls of the eukaryotic cell cycle
    B Novak
    Molecular Network Dynamics Research Group of Hungarian Academy of Sciences and Budapest University of Technology and Economics, 1521 Budapest, Gellert ter 4, Hungary
    Biochem Soc Trans 31:1526-9. 2003

Detail Information

Publications9

  1. ncbi request reprint Mathematical model of the fission yeast cell cycle with checkpoint controls at the G1/S, G2/M and metaphase/anaphase transitions
    B Novak
    Department of Agricultural Chemical Technology, Technical University of Budapest, Hungary
    Biophys Chem 72:185-200. 1998
    ..By numerical simulations we show that the model is consistent with a broad selection of cell cycle mutants, and we predict the phenotypes of several multiple-mutant strains that have not yet been constructed...
  2. pmc Model scenarios for evolution of the eukaryotic cell cycle
    B Novak
    Department of Agricultural Chemical Technology, Technical University of Budapest, Hungary
    Philos Trans R Soc Lond B Biol Sci 353:2063-76. 1998
    ....
  3. ncbi request reprint Finishing the cell cycle
    B Novak
    Department of Agricultural Chemical Technology, Technical University of Budapest, Gellert ter 4, Budapest, 1521, Hungary
    J Theor Biol 199:223-33. 1999
    ..The phosphatase acts in parallel pathways; hence, cells can leave mitosis in the absence of cyclin degradation or in the absence of the CKI...
  4. ncbi request reprint Mitotic control in the absence of cdc25 mitotic inducer in fission yeast
    A Sveiczer
    Department of Agricultural Chemical Technology, Technical University of Budapest, Szt Gellert ter 4, Hungary
    J Cell Sci 112:1085-92. 1999
    ..The inability of these cells to start anaphase might be caused by the absence of the main mitotic regulators (wee1 and cdc25) and the improper regulation of their back-up copies (mik1 and pyp3, respectively)...
  5. pmc Modeling the fission yeast cell cycle: quantized cycle times in wee1- cdc25Delta mutant cells
    A Sveiczer
    Department of Agricultural Chemical Technology, Budapest University of Technology and Economics, 1521 Budapest, Szt Gellert ter 4, Hungary
    Proc Natl Acad Sci U S A 97:7865-70. 2000
    ..Our quantitative description of these quantized cycles demonstrates the utility of mathematical modeling, because these cycles cannot be understood by intuitive arguments alone...
  6. ncbi request reprint Regularities and irregularities in the cell cycle of the fission yeast, Schizosaccharomyces pombe (a review)
    A Sveiczer
    Department of Agricultural Chemical Technology, Budapest University of Technology and Economics Szt Gellért tér 4, H 1111 Budapest, Hungary
    Acta Microbiol Immunol Hung 49:289-304. 2002
    ....
  7. ncbi request reprint A stochastic, molecular model of the fission yeast cell cycle: role of the nucleocytoplasmic ratio in cycle time regulation
    A Sveiczer
    Department of Agricultural Chemical Technology, Budapest University of Technology and Economics, 1521 Budapest, Szt Gellert ter 4, Hungary
    Biophys Chem 92:1-15. 2001
    ..We have simulated the cell-cycle statistics of populations of wild-type cells and of wee1(-) mutant cells. Our results are consistent with well known experimental observations...
  8. ncbi request reprint The size control of fission yeast revisited
    A Sveiczer
    Department of Agricultural Chemical Technology, Technical University of Budapest, Hungary
    J Cell Sci 109:2947-57. 1996
    ..Third, in rum1 delta wee1-50 where the normal long G1 in wee1 is much reduced, there is probably no size control either in G1 or in G2 causing a continuous shortening of division length from cycle to cycle...
  9. ncbi request reprint Modelling the controls of the eukaryotic cell cycle
    B Novak
    Molecular Network Dynamics Research Group of Hungarian Academy of Sciences and Budapest University of Technology and Economics, 1521 Budapest, Gellert ter 4, Hungary
    Biochem Soc Trans 31:1526-9. 2003
    ..With this comprehensive model, we also discuss the mechanisms by which different checkpoint pathways stabilize different cell-cycle states and inhibit the transitions that drive cell-cycle progression...